Tumor cell separation and collection device

Through the design of centrifugal rotation and gear system, tumor cells can be quickly captured and filtered, solving the problems of slow collection speed and poor separation effect of traditional devices, and achieving fast and efficient tumor cell separation and data acquisition.

CN223304429UActive Publication Date: 2025-09-05CHUANGMO BIOTECHNOLOGY (BEIJING) CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202422543269.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-21
Publication Date
2025-09-05
Estimated Expiration
2034-10-21

AI Technical Summary

Technical Problem

Traditional tumor cell separation and collection devices have a slow collection speed, resulting in a long collection process and possible deviations in the separation effect, which affects medical workers' rapid judgment and data accuracy.

Method used

It adopts centrifugal rotation, drives the separation shaft and gear system through the separation motor, combines the capture rod and filter membrane, realizes the rapid capture and filtration of tumor cells, and improves the separation efficiency.

Benefits of technology

It shortens the time for collecting tumor cells and improves the separation effect, ensuring that medical workers can quickly obtain accurate data to make judgments and reduce the impact of errors.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223304429U_ABST
    Figure CN223304429U_ABST
Patent Text Reader

Abstract

The utility model relates to the technical field of tumor cell separation and collection, in particular to a tumor cell separation and collection device which comprises a table body, a supporting assembly, a circulating assembly, a flowing assembly, a separation bin, a separation motor, a separation shaft, a first gear, a second gear, a catching rod and a filtering membrane. A supporting assembly playing a supporting role is arranged at the lower end of the table body, a circulating assembly playing a circulating role is arranged on the inner side of the table body, and a flowing assembly playing a flowing role is arranged on one side of the table body. The tumor cells are rapidly and efficiently separated and collected in a centrifugal rotation, filter membrane filtration and fixed capture mode, so that the time spent on collecting the tumor cells by the device is shortened, the tumor cell separation and collection effect of the device is improved, medical workers can obtain data more rapidly and make judgment, and the efficiency of collecting the tumor cells is improved. And misjudgment caused by data deviation due to poor tumor cell separation effect of the device is reduced.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of tumor cell separation and collection, in particular to a tumor cell separation and collection device. Background Art

[0002] Tumor cell separation and collection devices are technical equipment used to separate tumor cells from biological samples. These devices play an important role in the early diagnosis, treatment monitoring, and research of tumors. Physical property enrichment method: This method separates cells based on their physical properties, such as size, density, mechanical and dielectric properties. It is simple to operate, has high capture efficiency, can achieve high-throughput enrichment, and is independent of the expression of cell surface antigens, so tumor cells with better morphology can be collected.

[0003] Traditional tumor cell separation and collection devices are slow to collect tumor cells, making the collection process time-consuming and potentially biased. Consequently, medical professionals have to wait a long time to obtain data, hindering their ability to quickly prescribe the right medicine and making a diagnosis, potentially worsening the patient's condition. Furthermore, potential errors in the separation effect can lead to inaccurate data, impacting medical professionals' judgments.

[0004] Therefore, for the above-mentioned traditional tumor cell separation and collection device, the speed of collecting tumor cells is relatively slow during the process of separating and collecting tumor cells, which makes the collection process take a long time and the separation effect may be deviated. A method can be designed to use centrifugal rotation to quickly and efficiently separate and collect tumor cells, so that the time spent on collecting tumor cells is reduced and the separation effect is improved, so that medical workers can obtain data more quickly and make judgments, reducing the judgment of data due to poor separation effect. Utility Model Content

[0005] In order to overcome the problem that traditional tumor cell separation and collection devices have a relatively slow speed in the process of separating and collecting tumor cells, the collection process takes a long time and the separation effect may be deviated.

[0006] The technical solution of the utility model is: a tumor cell separation and collection device, including a platform body, a support component, a circulation component, a flow component, a separation chamber, a separation motor, a separation shaft, a first gear, a second gear, a capture rod and a filter membrane; a support component that plays a supporting role is provided at the lower end of the platform body, a circulation component that plays a circulation role is provided on the inner side of the platform body, a flow component that plays a flow role is provided on one side of the platform body, a separation motor is provided on the inner side of the platform body, a separation shaft is provided at the output end of the separation motor, a first gear is provided on the outer side of the separation shaft, a second gear is provided on one side of the first gear, a separation chamber is provided on the inner side of the second gear, a capture rod is provided on the inner side of the separation chamber, a plurality of capture rods are provided, and a filter membrane is provided on the inner side of the separation chamber.

[0007] Preferably, the support component plays a supporting role, thereby supporting the device, the circulation component plays a circulation role, thereby improving the separation effect, the flow component plays a flow role, thereby driving the blood flow, the separation motor drives the separation shaft to rotate, the rotation of the separation shaft drives the first gear to rotate, the rotation of the first gear drives the second gear to rotate, the rotation of the second gear drives the separation chamber to rotate, the rotation of the separation chamber drives the capture rod to move, the tumor cells are captured by the capture rod, and the tumor cells are filtered through the filter membrane, so that the time spent on collecting tumor cells is reduced and the separation effect is improved, so that medical workers can obtain data more quickly and make judgments, reducing the judgment of data due to poor separation effect.

[0008] Preferably, the support assembly includes a support platform and support columns; the support platform is provided at the lower end of the platform body, and the support columns are provided at the lower end of the support platform, and multiple groups of support columns are provided.

[0009] Preferably, the support assembly further includes a reinforcement column; a reinforcement column is provided on one side of the support column, and multiple groups of reinforcement columns are provided.

[0010] Preferably, the circulation component includes a first pipeline, a pump, a collecting chamber and a through port; a collecting chamber is provided at the upper end of the platform, a through port is opened on one side of the collecting chamber, a first pipeline is provided on the other side of the collecting chamber, and a pump is provided at the upper end of the first pipeline.

[0011] Preferably, the circulation component further includes a second pipeline and a circulation chamber; the second pipeline is provided at the upper end of the pump, and the circulation chamber is provided on one side of the second pipeline.

[0012] Preferably, the separation component includes a funnel and a fixed pipe; the funnel is provided at the upper end of the circulation bin, and the fixed pipe is provided at the lower end of the circulation bin.

[0013] Preferably, the separation component further includes a nut and a valve; a nut is provided on the outside of the fixed pipe, the nut is located above the separation chamber, and a valve is provided on one side of the separation chamber.

[0014] Beneficial effects of the utility model:

[0015] 1. The separation motor drives the separation shaft to rotate, the rotation of the separation shaft drives the first gear to rotate, the rotation of the first gear drives the second gear to rotate, the rotation of the second gear drives the separation chamber to rotate, the rotation of the separation chamber drives the capture rod to move, the capture rod is used to capture tumor cells, and the tumor cells are filtered through the filter membrane, so that the time spent on collecting tumor cells is reduced and the separation effect is improved, so that medical workers can obtain data more quickly and make judgments, reducing the judgment of data due to poor separation effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 Shown is a schematic diagram of the first three-dimensional structure of a tumor cell separation and collection device of the present invention;

[0017] Figure 2 Shown is a schematic diagram of the second three-dimensional structure of a tumor cell separation and collection device of the present invention;

[0018] Figure 3 Shown is a schematic diagram of the cross-sectional three-dimensional structure of a tumor cell separation and collection device of the present invention;

[0019] Figure 4 Shown is a schematic diagram of the partial three-dimensional structure of a tumor cell separation and collection device of the present invention.

[0020] Explanation of the accompanying drawings: 1. Platform body; 201. Support platform; 202. Support column; 203. Strengthening column; 301. First pipeline; 302. Pump; 303. Second pipeline; 304. Circulation chamber; 305. Collection chamber; 306. Port; 401. Funnel; 402. Fixed pipeline; 403. Nut; 404. Valve; 501. Separation chamber; 502. Separation motor; 503. Separation shaft; 504. First gear; 505. Second gear; 506. Capture rod; 507. Filter membrane. DETAILED DESCRIPTION

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] See also Figure 1-Figure 4The utility model provides an embodiment: a tumor cell separation and collection device, including a platform 1, a support component, a circulation component, a flow component, a separation chamber 501, a separation motor 502, a separation shaft 503, a first gear 504, a second gear 505, a capture rod 506 and a filter membrane 507; a support component that plays a supporting role is provided at the lower end of the platform body 1, a circulation component that plays a circulation role is provided on the inner side of the platform body 1, a flow component that plays a flow role is provided on one side of the platform body 1, a separation motor 502 is provided on the inner side of the platform body 1, a separation shaft 503 is provided at the output end of the separation motor 502, a first gear 504 is provided on the outer side of the separation shaft 503, a second gear 505 is provided on one side of the first gear 504, a separation chamber 501 is provided inside the second gear 505, a capture rod 506 is provided inside the separation chamber 501, a plurality of capture rods 506 are provided, and a filter membrane 507 is provided inside the separation chamber 501.

[0023] See also Figure 1-Figure 4 In this embodiment, the support assembly includes a support platform 201 and a support column 202; the support platform 201 is provided at the lower end of the platform body 1, and the support column 202 is provided at the lower end of the support platform 201. There are multiple groups of support columns 202. When in use, the force of the device is dispersed through the support platform 201, and the device is supported by the support column 202 to prevent the device from collapsing; the support assembly also includes a reinforcement column 203; a reinforcement column 203 is provided on one side of the support column 202, and there are multiple groups of reinforcement columns 203. When in use, the force of the support column 202 is dispersed through the reinforcement column 203, so as to prevent the device from collapsing. To prevent the device from shaking; the circulation component includes a first pipe 301, a pump 302, a collection chamber 305 and a through port 306; the upper end of the platform body 1 is provided with a collection chamber 305, one side of the collection chamber 305 is provided with a through port 306, the other side of the collection chamber 305 is provided with a first pipe 301, and the upper end of the first pipe 301 is provided with a pump 302. When in use, the separated blood is collected through the collection chamber 305, the blood is discharged through the through port 306, the blood is transported through the first pipe 301, and the blood is circulated by the pump 302, thereby facilitating blood circulation;

[0024] The circulation component also includes a second pipe 303 and a circulation chamber 304; a second pipe 303 is provided at the upper end of the pump 302, and a circulation chamber 304 is provided on one side of the second pipe 303. When in use, blood is transported through the second pipe 303 and concentrated through the circulation chamber 304, thereby assisting blood circulation; the separation component includes a funnel 401 and a fixed pipe 402; a funnel 401 is provided at the upper end of the circulation chamber 304, and a fixed pipe 402 is provided at the lower end of the circulation chamber 304. When in use, blood is added through the funnel 401 and transported through the fixed pipe 402, thereby facilitating blood separation; the separation component also includes a nut 403 and a valve 404; a nut 403 is provided on the outside of the fixed pipe 402, the nut 403 is located above the separation chamber 501, and a valve 404 is provided on one side of the separation chamber 501. When in use, the separation chamber 501 is fixed by the nut 403, and the opening and closing of the separation chamber 501 is controlled by the valve 404, thereby preventing the separated material from falling off.

[0025] During operation, the support platform 201 first disperses the force on the device, and the support column 202 supports the device to prevent it from collapsing. The reinforcement column 203 disperses the force on the support column 202 to prevent the device from shaking. Then, blood is added through the funnel 401 and transported through the fixed pipe 402 to facilitate blood separation.

[0026] Secondly, the separation motor 502 drives the separation shaft 503 to rotate, which in turn drives the first gear 504 to rotate, which in turn drives the second gear 505 to rotate, which in turn drives the separation chamber 501 to rotate, which in turn drives the capture rod 506 to move, and the capture rod 506 captures the tumor cells, which are then filtered through the filter membrane 507, thereby reducing the time spent on collecting the tumor cells.

[0027] Finally, the separated blood is collected through the collection chamber 305, discharged through the port 306, transported through the first pipe 301, circulated through the pump 302, transported through the second pipe 303, and concentrated through the circulation chamber 304, thereby assisting blood circulation; the separation chamber 501 is then fixed by the nut 403, and the opening and closing of the separation chamber 501 is controlled by the valve 404, thereby preventing the separated material from falling off.

[0028] Through the above steps, the support component plays a supporting role, thereby supporting the device, the circulation component plays a circulation role, thereby improving the separation effect, the flow component plays a flow role, thereby driving blood flow, the separation motor 502 is used to drive the separation shaft 503 to rotate, the separation shaft 503 is used to drive the first gear 504 to rotate, the first gear 504 is used to drive the second gear 505 to rotate, the second gear 505 is used to drive the separation chamber 501 to rotate, the separation chamber 501 is used to drive the capture rod 506 to move, the capture rod 506 is used to capture tumor cells, and the filter membrane 507 is used to filter the tumor cells, so that the time spent on collecting tumor cells is reduced and the separation effect is improved, so that medical workers can obtain data more quickly and make judgments, reducing the judgment of data due to poor separation effect.

[0029] The embodiments of the present invention are described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the purpose of the present invention.

Claims

1. A tumor cell separation and collection device, comprising a body (1); characterized in that: The apparatus further comprises a support assembly, a circulation assembly, a flow assembly, a separation chamber (501), a separation motor (502), a separation shaft (503), a first gear (504), a second gear (505), a capture rod (506) and a filter membrane (507); a support assembly for supporting is provided at the lower end of the platform body (1); a circulation assembly for circulating is provided on the inner side of the platform body (1); a flow assembly for flowing is provided on one side of the platform body (1); and a filter is provided on the inner side of the platform body (1). A separation motor (502) is provided at the output end of the separation motor (502), a separation shaft (503) is provided on the outside of the separation shaft (503), a second gear (505) is provided on one side of the first gear (504), a separation chamber (501) is provided on the inside of the second gear (505), a capture rod (506) is provided on the inside of the separation chamber (501), a plurality of capture rods (506) are provided, and a filter membrane (507) is provided on the inside of the separation chamber (501).

2. The device for separating and collecting tumor cells according to claim 1, characterized in that: The support assembly comprises a support platform (201) and support columns (202); the support platform (201) is provided at the lower end of the platform body (1), and the support columns (202) are provided at the lower end of the support platform (201), and the support columns (202) are provided in multiple groups.

3. The device for separating and collecting tumor cells according to claim 2, characterized in that: The support assembly further comprises a reinforcement column (203); a reinforcement column (203) is provided on one side of the support column (202), and the reinforcement column (203) is provided in multiple groups.

4. The device for separating and collecting tumor cells according to claim 1, characterized in that: The circulation component comprises a first pipeline (301), a pump (302), a collection chamber (305) and a through-port (306); the collection chamber (305) is provided at the upper end of the platform body (1); a through-port (306) is provided on one side of the collection chamber (305); the first pipeline (301) is provided on the other side of the collection chamber (305); and the pump (302) is provided at the upper end of the first pipeline (301).

5. The device for separating and collecting tumor cells according to claim 4, characterized in that: The circulation component further comprises a second pipeline (303) and a circulation chamber (304); the second pipeline (303) is provided at the upper end of the pump (302), and the circulation chamber (304) is provided on one side of the second pipeline (303).

6. The device for separating and collecting tumor cells according to claim 4, characterized in that: The separation component comprises a funnel (401) and a fixed pipe (402); the funnel (401) is provided at the upper end of the circulation chamber (304), and the fixed pipe (402) is provided at the lower end of the circulation chamber (304).

7. The device for separating and collecting tumor cells according to claim 6, characterized in that: The separation assembly further comprises a nut (403) and a valve (404); a nut (403) is provided on the outside of the fixed pipe (402), the nut (403) is located above the separation chamber (501), and a valve (404) is provided on one side of the separation chamber (501).