Portable antibody adding device
By introducing a light-shielding cover, an adjustment component and a cover into the antibody adding device, the problems of insufficient light protection and portability of the antibody adding device are solved, and effective protection of the antibodies and safety and convenience of operation are achieved.
Patent Information
- Application Number
- CN202422662732.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-01
- Publication Date
- 2025-09-09
- Estimated Expiration
- 2034-11-01
AI Technical Summary
Existing antibody addition devices have deficiencies in light protection and portability, which may lead to antibody inactivation or inconvenience in operation, affecting the accuracy of experimental results and posing safety risks.
A convenient antibody addition device was designed, which includes a light shield, an adjustment component and a cover. The light shield prevents light from damaging the antibody, the adjustment component facilitates the storage and use of the needle, and the cover prevents the needle from accidentally injuring the operator.
It effectively prevents antibodies from being inactivated by light, improves the accuracy of experimental results, and reduces the number of operating steps through its convenient design, thereby improving portability and ease of operation.
Smart Images

Figure CN223312091U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of antibody adding devices, in particular to a portable antibody adding device. Background Art
[0002] A portable antibody addition device is a device used to quickly and conveniently add antibodies to samples or reactions. It is typically used in laboratory research, diagnostic testing, or treatment processes, improving work efficiency and reducing operational steps.
[0003] For example, the patent publication number CN213000063 U describes a device suitable for adding antibodies to the production process of an immunoaffinity column. The solution described therein is as follows: through the combined use of accessories, a controller carrying a control panel can be assembled on the top of the air pump, and an air pipe carrying an inner tube can be assembled at the output end of the air pump. The air pipe has a porous nail with an inner groove, which can be assembled with the outer protrusion on the combination cap to allow the porous nail to pierce the sealing film on the nail hole. After removing the hole plug, the antibody in the antibody column is added to the production process of the immunoaffinity column, thereby avoiding the oxidation probability of the antibody during the transfer process before addition, having good sealing performance, and eliminating the disadvantages of cleaning the inside of the device when the adding device is not in direct contact with the antibody, thereby reducing the difficulty of work and ensuring the cleanliness of the antibody addition process.
[0004] In the above case, when adding antibodies that need to be protected from light, it is difficult to protect the antibodies from light, which may cause some antibodies to become inactivated, thereby affecting the accuracy of the experimental results. At the same time, the above case is not convenient to carry, and the antibody column is exposed to the outside when carried, which may cause it to break or accidentally injure the operator. Utility Model Content
[0005] The purpose of the present invention is to provide a convenient antibody adding device to solve the problems in the background technology.
[0006] To achieve the above objectives, the present invention provides the following technical solutions:
[0007] Convenient antibody addition device, including:
[0008] column shaft;
[0009] A storage block, the storage block being installed at the bottom of the column body;
[0010] A fixed block, the fixed block being installed on the top of the column body;
[0011] It also includes a needle, which is arranged inside the storage block, a telescopic tube is provided between the needle and the column body, an electromagnetic valve is provided on the telescopic tube, a piston is slidably connected to the inside of the column body, a connecting rod is installed on the top of the piston, and the connecting rod is slidably connected to the top of the column body, and an adjustment component for adjusting the position of the needle is provided on the storage block.
[0012] On the basis of the above technical solutions, the present invention also provides the following optional technical solutions:
[0013] In an optional scheme: the adjustment component includes a connecting block, the connecting block is installed on the top of the needle, sliders are provided on both sides of the connecting block, and sliding grooves corresponding to the positions of the sliders are provided on the inner wall of the storage block. The two ends of one side of the connecting block are fixedly connected with connecting rods, and the storage block is provided with sliding grooves corresponding to the positions of the connecting rods. The two connecting rods are passed through one end of the storage block and a sliding block is installed. The interior of the sliding block is slidably connected with a card column, and the card column is movably connected to the interior of the connecting block. The storage block is provided with a number of through grooves corresponding to the positions of the card columns.
[0014] In an optional solution, a protection component for protecting the column body is provided on the fixing block.
[0015] In an optional solution: the protective component includes a light-shielding cover, which is movably connected to the bottom of the fixed block, and sliding grooves are provided on both sides of the top of the light-shielding cover. The inside of the sliding groove is slidably connected to a snap-in block, and a spring is installed between the snap-in block and the sliding groove. The bottom of the fixed block is provided with a snap-in groove corresponding to the position of the snap-in block.
[0016] In an optional solution, the bottom of the storage block is movably connected to a cover.
[0017] In an optional solution, a pressing plate is installed on the top of the connecting rod.
[0018] In an optional solution, the top of the clamping block is hook-shaped.
[0019] In an optional solution: the light-shielding cover is sleeved on the outer wall of the column body.
[0020] Compared with the prior art, the beneficial effects of the present invention are as follows:
[0021] The utility model adopts a light-shield to effectively prevent the inactivation of antibodies due to light, thereby ensuring the accuracy of the experimental results. The light-shield is detachable, which is convenient for the operator to extract different antibodies. The adjustment component is provided to effectively store and use the needle, avoiding the operator having nowhere to store the needle when carrying it and easily injuring the operator by mistake. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 It is a structural diagram of the present utility model.
[0023] Figure 2 It is a schematic diagram of the cutaway structure of the present utility model.
[0024] Figure 3 It is a schematic diagram of the enlarged structure of A in the utility model 2.
[0025] Figure 4 For this utility model Figure 2 Schematic diagram of the enlarged structure of B.
[0026] Among them: 100, column body; 200, storage block; 300, fixed block; 401, needle; 403, piston; 404, connecting rod; 501, connecting block; 502, slider; 503, slide groove; 504, connecting rod; 505, sliding block; 506, clamping column; 507, through groove; 601, light shield; 602, sliding groove; 603, clamping block; 604, spring; 605, clamping groove; 701, sealing cover; 702, pressing plate. DETAILED DESCRIPTION
[0027] In order to make the purpose, technical solutions and advantages of the present invention more clear, the present invention is further described in detail below with reference to the accompanying drawings and embodiments.
[0028] In one embodiment, Figure 1-Figure 3 As shown, the portable antibody adding device comprises: a column 100, a storage block 200, a fixing block 300 and a needle 401, wherein the storage block 200 is installed at the bottom of the column 100, the fixing block 300 is installed at the top of the column 100, the needle 401 is arranged inside the storage block 200, a telescopic tube is provided between the needle 401 and the column 100, the telescopic tube is provided with a solenoid valve, a piston 403 is slidably connected to the interior of the column 100, a connecting rod 404 is installed on the top of the piston 403, the connecting rod 404 is slidably connected to the top of the column 100, and an adjustment component for adjusting the position of the needle 401 is provided on the storage block 200; by first opening the solenoid valve, the needle 401 is aligned with the antibody to be added, and then the connecting rod 404 is pulled up and down to drive the piston 403 to move up and down, so that a negative pressure state is formed inside the column 100, so that the needle 401 draws the antibody into the column 100.
[0029] In one embodiment, Figure 2 and Figure 4As shown, the adjustment component includes a connecting block 501, which is installed on the top of the needle 401, and sliders 502 are provided on both sides of the connecting block 501. A sliding groove 503 corresponding to the position of the slider 502 is provided on the inner wall of the storage block 200, and the two ends of one side of the connecting block 501 are fixedly connected to a connecting rod 504, and the storage block 200 is provided with a sliding groove corresponding to the position of the connecting rod 504. The two connecting rods 504 are passed through one end of the storage block 200 and a sliding block 505 is installed. The interior of the sliding block 505 is slidably connected to a card column 506, and the card column 506 is movably connected to the interior of the connecting block 501. 0 is provided with several through slots 507 corresponding to the positions of the card columns 506; first, the card column 506 is pulled out of the storage block 200, and then the sliding block 505 is moved up and down, so that the sliding block 505 drives the connecting rod 504 and the connecting block 501 to move, and the sliding block 502 and the sliding slot 503 are used to move up and down to prevent the connecting block 501 from deviating from the position during the displacement process. After the connecting block 501 moves, it drives the needle 401 to move up and down. When the needle 401 moves to the appropriate position, the card column 506 is aligned with the through slot 507, clamped into the storage block 200, and then clamped into the interior of the connecting block 501 to fix the position of the needle 401, which is convenient for extracting the antibody.
[0030] In one embodiment, Figure 2 and Figure 3 As shown, the protective assembly includes a light shield 601, which is movably connected to the bottom of the fixed block 300. Sliding grooves 602 are provided on both sides of the top of the light shield 601. A clamping block 603 is slidably connected to the inside of the sliding groove 602. A spring 604 is installed between the clamping block 603 and the sliding groove 602. A clamping groove 605 corresponding to the position of the clamping block 603 is provided at the bottom of the fixed block 300. By putting the light shield 601 on the column body 1 from bottom to top 00 outside, and then press the clamping block 603 toward the column body 100 at the same time. The clamping block 603 squeezes the spring 604 to move closer to the column body 100. At this time, the light shield 601 is close to the bottom of the fixing block 300, and the clamping block 603 is aligned with the clamping groove 605. Then the clamping block 603 is released. At this time, the spring 604 is no longer squeezed, and the spring 604 drives the clamping block 603 to move toward the light shield 601. The clamping block 603 and the clamping groove 605 abut against each other, and the light shield 601 can be fixed.
[0031] In one embodiment, Figure 2 As shown, a cover 701 is movably connected to the bottom of the storage block 200; the cover 701 can prevent the needle 401 from accidentally injuring the operator when carrying the adding device.
[0032] In one embodiment, Figure 1 and Figure 2 As shown, a pressing plate 702 is installed on the top of the connecting rod 404; the pressing plate 702 can be used to press the connecting rod 404 downward and pull it upward.
[0033] In one embodiment, Figure 3 As shown, the top of the clamping block 603 is hook-shaped, which is convenient for cooperating with and abutting against the clamping slot 605 .
[0034] In one embodiment, Figure 1 and Figure 2 As shown, the light shield 601 is sleeved on the outer wall of the column body 100; the light shield 601 can be used when some light-shielding antibodies need to be added, and can effectively avoid direct light.
[0035] The above embodiment discloses a convenient antibody adding device, wherein, first, it is determined whether the antibody needs to be protected from light. When it needs to be protected from light, the light shield 601 is put on the outside of the column body 100 from bottom to top, and then the clamping block 603 is pressed toward the column body 100 at the same time. The clamping block 603 squeezes the spring 604 to move closer to the column body 100. At this time, the light shield 601 is close to the bottom of the fixing block 300, and the clamping block 603 is aligned with the clamping groove 605. Then the clamping block 603 is released. At this time, the spring 604 is no longer squeezed, and the spring 604 drives the clamping block 603 to move toward the light shield 601. The clamping block 603 and the clamping groove 605 abut against each other, and the light shield 601 can be fixed. Then the card column 506 is pulled out of the storage block 200, and then the sliding block 505 is moved up and down. The sliding block 505 drives the connecting rod 504 and the connecting block 501 to move, and moves up and down with the assistance of the slider 502 and the slide groove 503 to prevent the connecting block 501 from deviating from its position during the displacement process. After the connecting block 501 moves, it drives the needle 401 to move up and down. When the needle 401 moves to the appropriate position, the card column 506 is aligned with the through groove 507, clamped into the storage block 200, and then clamped into the interior of the connecting block 501 to fix the position of the needle 401, which is convenient for extracting the antibody. Then, the solenoid valve is opened, and the needle 401 is aligned with the antibody to be added. Then, the pressing plate 702 and the connecting rod 404 are pulled up and down to drive the piston 403 to move up and down, so that a negative pressure state is formed inside the column body 100, so that the needle 401 extracts the antibody into the column body 100.
[0036] The above description is merely a specific embodiment of the present application, but the scope of protection of the present application is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in this application should be included in the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.
Claims
1. Convenient antibody addition device, including: Column body (100); A storage block (200), the storage block (200) being installed at the bottom of the column body (100); A fixing block (300), the fixing block (300) being installed on the top of the column body (100); The invention is characterized in that it further comprises a needle (401), the needle (401) being arranged inside the storage block (200), a telescopic tube being arranged between the needle (401) and the column body (100), a solenoid valve being arranged on the telescopic tube, a piston (403) being slidably connected inside the column body (100), a connecting rod (404) being installed on the top of the piston (403), the connecting rod (404) being slidably connected to the top of the column body (100), and an adjusting component for adjusting the position of the needle (401) being arranged on the storage block (200).
2. The portable antibody adding device according to claim 1, characterized in that: The adjusting component includes a connecting block (501), the connecting block (501) is installed on the top of the needle (401), sliders (502) are provided on both sides of the connecting block (501), and a sliding groove (503) corresponding to the position of the slider (502) is provided on the inner wall of the storage block (200), and the two ends of one side of the connecting block (501) are fixedly connected with a connecting rod (504), and the storage block (200) is provided with a sliding groove corresponding to the position of the connecting rod (504), and the two connecting rods (504) are passed through one end of the storage block (200) and are installed with a sliding block (505), and the interior of the sliding block (505) is slidably connected to a card column (506), and the card column (506) is movably connected to the interior of the connecting block (501), and the storage block (200) is provided with a plurality of through grooves (507) corresponding to the position of the card column (506).
3. The portable antibody adding device according to claim 1, characterized in that: The fixing block (300) is provided with a protection component for protecting the column body (100).
4. The portable antibody adding device according to claim 3, characterized in that: The protective component includes a light shield (601), which is movably connected to the bottom of the fixed block (300), and sliding grooves (602) are provided on both sides of the top of the light shield (601). The interior of the sliding groove (602) is slidably connected to a clamping block (603), and a spring (604) is installed between the clamping block (603) and the sliding groove (602). The bottom of the fixed block (300) is provided with a clamping groove (605) corresponding to the position of the clamping block (603).
5. The portable antibody adding device according to claim 1, characterized in that: The bottom of the storage block (200) is movably connected to a cover (701).
6. The portable antibody adding device according to claim 1, characterized in that: A pressing plate (702) is installed on the top of the connecting rod (404).
7. The portable antibody adding device according to claim 4, characterized in that: The top of the clamping block (603) is hook-shaped.
8. The portable antibody adding device according to claim 4, characterized in that: The light shield (601) is sleeved on the outer wall of the column body (100).
Citation Information
Patent Citations
Antibody adding device suitable for immunoaffinity column production process
CN213000063U