Ice bucket device for chromosome dropping
By designing an ice bucket device for chromosome drop slices, the problems of inconvenient operation and high cost in the prior art are solved, and the operation process is simplified and the drop slice efficiency is improved.
Patent Information
- Application Number
- CN202422149183.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-03
- Publication Date
- 2025-09-09
- Estimated Expiration
- 2034-09-03
AI Technical Summary
The existing technology lacks a dedicated manual chromosome drop device, which is inconvenient to operate and expensive, and cannot meet the needs of some laboratories with small specimen quantities.
An ice bucket device for chromosome slides was designed, which includes an ice bucket and a basket. The basket is provided with a ring platform and a fixing buckle, which can stably place the slide in the ice-water mixture, simplify the operation process and ensure a low-temperature environment.
It improves the operational efficiency of chromosome droplets, reduces operation time and cost, ensures that the slides are stably placed in a low-temperature environment, and improves the droplet speed and quality.
Smart Images
Figure CN223315598U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of chromosome analysis, in particular to an ice bucket device for chromosome droplets. Background Art
[0002] Chromosome karyotype analysis is a method used to observe and analyze the number and structure of chromosomes in cells. It is an important tool in genetic research and auxiliary clinical diagnosis. It is a key indicator for analyzing chromosome translocations and deletions and diagnosing various genetic diseases. It also provides an important basis for the study of cell genetic classification, interspecies relationships, and chromosome number and structural variation. Chromosome karyotype analysis is mainly divided into peripheral blood chromosome karyotype analysis and chorionic villus, amniotic fluid, and umbilical cord blood karyotype analysis. Peripheral blood karyotype analysis is generally used for patients with infertility, tumors, etc.; chorionic villus, amniotic fluid, and umbilical cord blood karyotype analysis is the gold standard for prenatal diagnosis. By detecting fetal chromosomes, it can prevent congenital abnormalities and plays a vital role in prenatal diagnosis.
[0003] The slide is a crucial step in karyotyping analysis. Its quality determines the subsequent level of chromosome resolution. Structural abnormalities in some small fragments require high-resolution karyotypes for diagnosis. The slide must be kept cold in an ice-water mixture during the slide process. This ensures that the karyotypes are dispersed, preventing them from overlapping or clumping together, facilitating counting and observation. Pre-cooling the slide forms a uniform film of water on the surface. When the cell suspension is dropped onto the slide, the droplet disperses immediately. Immediately exposing the slide to a high temperature allows for better dispersion of the karyotypes.
[0004] At present, there is no dedicated manual chromosome drop device to hold the ice-water mixture. Operators place the slides directly in the basin. The ice cubes will float on the water surface, and the slides will sink to the bottom of the basin, which is extremely inconvenient to retrieve. It increases the operation time and reduces the drop speed. Long-term operation requires repeated addition of ice cubes.
[0005] Although there are mechanical drop-slide devices on the market, they are expensive and cumbersome to operate. For laboratories with small specimen quantities or situations where repeated drop-slides are temporarily required, the instrument operation takes longer and is more expensive than manual operation, which is not applicable from the perspective of health economics. Utility Model Content
[0006] The purpose of the utility model is to provide an ice bucket device for chromosome droplets.
[0007] An ice bucket device for chromosome drop slices, comprising an ice bucket and a basket;
[0008] An outer edge of the ice bucket is provided at the upper edge;
[0009] The basket is placed in the ice bucket, and a ring-shaped platform is provided on the upper part of the basket. The ring-shaped platform is placed above the outer edge, the inner diameter of the ring-shaped platform is smaller than the inner diameter of the ice bucket, and the outer diameter of the ring-shaped platform is larger than the outer diameter of the outer edge. A small hole is opened on the ring-shaped platform, and the upper end of the fixing buckle is placed in the small hole;
[0010] There is a water leakage hole at the bottom of the basket.
[0011] Furthermore, the height of the basket is 5cm-8cm; the width of the annular platform is 2cm-2.5cm; the height of the annular platform is 2cm-2.5cm; and the lower edge of the annular platform is rolled inward and has a smooth edge.
[0012] Furthermore, there are two small holes on each side of the annular platform. The small holes on both sides are symmetrical with the center of the ice bucket, and the distance between the centers of the two small holes on the same side is 1 cm.
[0013] Furthermore, the number of the water leakage holes is 2, 4, 6 or 8.
[0014] Furthermore, a handle is provided on the upper side of the basket.
[0015] Furthermore, the fixing buckle is an S-shaped buckle, which can be rotated 90 degrees with the upper end of the fixing buckle in the small hole as the rotation axis. The outer side of the upper end of the fixing buckle can be fixed to the outside of the annular platform, and the outer edge of the lower corner of the fixing buckle is fixed to the lower side of the ice bucket.
[0016] The beneficial effects of the utility model are:
[0017] 1. The ice bucket device for chromosome droplets is easy to install, flexible and quick to operate, and saves time. The ice bucket of the device can directly freeze ice cubes, and the ice content is large, which fully ensures that the slides are always in a low-temperature environment, while reducing the link of adding ice cubes and simplifying the operation steps; there is a basket inside the ice bucket to ensure that the slides are completely immersed in ice water. At the same time, the height of the basket is appropriate, which makes it convenient for the operator to pick up the slides and speed up the droplet. An annular platform is set above the basket. The annular platform has a certain width and can be adapted to ice buckets of different inner diameters. The laboratory can adjust it in time according to its actual situation. In addition, the lower edge of the annular platform is rolled inward and the surface is smooth to prevent the operator from scratching his hands due to the sharp outer edge when picking up the slides.
[0018] 2. The ice bucket device for chromosome slides features a rotatable retaining buckle on the basket. When the buckle is parallel to the outer wall of the ice bucket, the basket can be lifted directly out of the bucket, facilitating the recovery of remaining slides. When the buckle is perpendicular to the outer wall of the ice bucket, the basket is secured, preventing it from floating out of the water due to ice cubes. This would prevent the slides from being fully immersed in the ice bucket, affecting the formation of an ice film on the slides, and thus affecting the slide drop quality. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 This is a front view of an ice bucket device for chromosome droplets.
[0020] Figure 2 This is the main view of the ice bucket.
[0021] Figure 3 This is the main view of the basket.
[0022] Figure 4 This is a top view of the basket.
[0023] Figure 5 A cross-sectional view of an ice bucket device used for chromosome droplets.
[0024] Figure 6 This is a diagram of the fixing buckle.
[0025] In the picture: 1. Ice bucket, 2. Handle, 3. Outer edge, 4. Ring platform, 5. Small hole, 6. Fixing buckle, 7. Drain hole, 8. Handle. DETAILED DESCRIPTION
[0026] The present invention will be further described below with reference to the embodiments and the accompanying drawings, but is not limited thereto.
[0027] Example 1
[0028] like Figure 1 As shown, an ice bucket device for chromosome droplets includes an ice bucket 1 and a basket 2; Figure 2 、 Figure 3 and Figure 4 As shown, an outward-rolled outer edge 3 is provided at the upper edge of the ice bucket 1; the handle 2 is placed in the ice bucket 1, and a circle of annular platforms 4 are provided on the upper part of the handle 2, and the annular platform 4 is placed on the outer edge 3. The inner diameter of the annular platform 4 is smaller than the inner diameter of the ice bucket 1, and the outer diameter of the annular platform 4 is larger than the outer diameter of the outer edge 3. A small hole 5 is provided on the annular platform 4, and the upper end of the fixing buckle 6 is placed in the small hole 5; a drainage hole 7 is provided at the bottom of the handle 2. The height of the handle 2 is 6 cm; the width of the annular platform 4 is 2 cm; the height of the annular platform 4 is 2 cm; the lower edge of the annular platform 4 is rolled inward, and the edge is smooth. There are two small holes 5 on each side of the annular platform 4, and the small holes 5 on both sides are symmetrical with the center of the ice bucket 1, and the distance between the centers of the two small holes 5 on the same side is 1 cm. There are 4 drainage holes 7. A handle 8 is provided on the upper side of the handle 2. As shown Figure 6 As shown, the fixing buckle 6 is an S-shaped buckle, which can be rotated 90 degrees with the upper end of the fixing buckle 6 in the small hole 5 as the rotation axis; the outer side of the upper end of the fixing buckle 6 can be fixed to the outside of the annular platform 4, and the outer edge of the lower corner of the fixing buckle 6 is fixed to the lower side of the ice bucket 1.
[0029] like Figure 5As shown, during use: fill ice bucket 1 with an ice-water mixture, place basket 2 inside, and rotate retaining buckle 6 so that it is perpendicular to the outer wall of ice bucket 1 to secure it. Place a glass slide in basket 2, and ice water will soak the slide through drain hole 7, ensuring it remains at a low temperature. This allows an ice film to form on the slide during the dripping process. After the dripping process is complete, rotate retaining buckle 6 so that it is parallel to the outer wall of ice bucket 1. Then, remove basket 2, filter out the water, and facilitate the recovery of the remaining glass slides.
[0030] Matters not covered in this utility model are known technologies.
[0031] The above embodiments are intended only to illustrate the technical concepts and features of the present invention. Their purpose is to enable those familiar with the art to understand the contents of the present invention and implement them accordingly. They are not intended to limit the scope of protection of the present invention. Any equivalent changes or modifications based on the spirit of the present invention are intended to be included in the scope of protection of the present invention.
Claims
1. An ice bucket device for chromosome droplets, characterized by: The ice bucket device for chromosome droplets comprises an ice bucket (1) and a basket (2); An outer edge (3) with an outward curl is provided at the upper edge of the ice bucket (1); The handle basket (2) is placed in the ice bucket (1), and a ring-shaped platform (4) is provided on the upper part of the handle basket (2). The ring-shaped platform (4) is placed on the outer edge (3). The inner diameter of the ring-shaped platform (4) is smaller than the inner diameter of the ice bucket (1), and the outer diameter of the ring-shaped platform (4) is larger than the outer diameter of the outer edge (3). A small hole (5) is opened on the ring-shaped platform (4), and the upper end of the fixing buckle (6) is placed in the small hole (5); The bottom of the basket (2) is provided with a water leakage hole (7).
2. The chromosome dropper ice bucket device according to claim 1, characterized in that: The height of the basket (2) is 5cm-8cm; the width of the annular platform (4) is 2cm-2.5cm; the height of the annular platform (4) is 2cm-2.5cm; the lower edge of the annular platform (4) is rolled inward and has a smooth edge.
3. The chromosome dropper ice bucket device according to claim 1, characterized in that: There are two small holes (5) on both sides of the annular platform (4), and the small holes (5) on both sides are symmetrical with respect to the center of the ice bucket (1). The distance between the centers of the two small holes (5) on the same side is 1 cm.
4. The chromosome dropper ice bucket device according to claim 1, characterized in that: The number of the water leakage holes (7) is 2, 4, 6 or 8.
5. The chromosome dropper ice bucket device according to claim 1, characterized in that: A handle (8) is provided on the upper side of the basket (2).
6. The chromosome dropper ice bucket device according to claim 1, characterized in that: The fixing buckle (6) is an S-shaped buckle, which can be rotated 90 degrees with the upper end of the fixing buckle (6) in the small hole (5) as the rotation axis. The outer side of the upper end of the fixing buckle (6) can be fixed to the outer side of the annular platform (4), and the outer edge of the lower corner of the fixing buckle (6) is fixed to the lower side of the ice bucket (1).