Stirring device

Abstract

The utility model relates to a stirring device which comprises a ventilation pipe, a ventilation structure and a stirring paddle, and the upper end of the ventilation pipe is used for ventilation and is used for being in driving connection with a driving piece; the ventilation structure is connected to the lower end of the ventilation pipe and comprises a connecting pipe connected to the lower end of the ventilation pipe and a ventilation ring pipe communicated with the connecting pipe, and a plurality of through holes distributed at intervals are formed in the ventilation ring pipe; the stirring paddle comprises a shaft sleeve and a plurality of blades, the shaft sleeve surrounds the periphery of the ventilation pipe and is arranged close to the ventilation ring pipe, and the blades are distributed on the periphery of the shaft sleeve at intervals in the circumferential direction of the shaft sleeve. The ventilation pipe and the stirring paddle are integrated, so that the occupied space of the stirring device is reduced, and the weight is reduced. The ventilation ring pipe rotates along with the stirring paddle, bubbles are distributed more uniformly in the culture solution, and mixing and mass transfer of the culture solution can be better carried out.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a stirring device. Background Art

[0002] Currently, glass jars on the market are equipped with stirring paddles, but ventilation is achieved through a separate fixed ventilation ring tube. The position of the vent holes remains unchanged, which cannot effectively mix the culture medium and transfer mass (such as oxygen). In addition, the independent ventilation tube takes up additional space in the tank. Utility Model Content

[0003] Based on the above description, the present invention provides a stirring device to solve the problem that the existing stirring paddle has a general mixing function and the ventilation pipe used in conjunction with it occupies space in the tank.

[0004] The technical solution of the utility model to solve the above technical problems is as follows:

[0005] A stirring device comprising:

[0006] A vent pipe, the upper end of which is used for ventilation and is connected to the driving member;

[0007] a ventilation structure connected to the lower end of the ventilation pipe, the ventilation structure comprising a connecting pipe connected to the lower end of the ventilation pipe and a ventilation ring pipe communicating with the connecting pipe, the ventilation ring pipe being provided with a plurality of through holes distributed at intervals; and

[0008] The stirring paddle comprises a shaft sleeve and a plurality of blades. The shaft sleeve surrounds the periphery of the ventilation pipe and is arranged close to the ventilation ring pipe. The plurality of blades are distributed at intervals along the circumference of the shaft sleeve on the periphery thereof.

[0009] Optionally, the stirring device also includes a stirring shaft head, the inner hole of the stirring shaft head is divided into a first hole portion, a second hole portion and a third hole portion which are connected in sequence along its axial direction, the first hole portion is used for installing the driving shaft of the driving member, the aperture of the second hole portion is smaller than the first hole portion and the third hole portion, and the third mounting hole is used for the upper end of the ventilation pipe to be inserted and welded.

[0010] Optionally, the stirring shaft head is further provided with a first top screw hole extending in its radial direction, and the first top screw hole is connected to the first hole portion;

[0011] The stirring device further includes a first jackscrew, which passes through the first jackscrew hole to abut against the driving shaft.

[0012] Optionally, the connecting tube is bent, and one end of the connecting tube is connected to the lower end of the ventilation pipe, and the other end is welded to the inner side of the ventilation ring tube, so that the ventilation ring tube and the ventilation pipe form a passage and are coaxially arranged.

[0013] Optionally, a threaded hole is formed at the lower portion of the inner hole of the vent pipe;

[0014] The ventilation structure further includes a sleeve-shaped connecting piece, the connecting piece including a screw and a protrusion connected to each other, the screw being screwed into the threaded hole, and the end surface of the protrusion facing the screw being a stepped surface;

[0015] The connecting pipe is welded in the inner hole of the connecting piece.

[0016] Optionally, the stirring device further comprises a sealing ring, which is provided at the lower part of the inner hole of the vent hole and abuts against the step surface;

[0017] The connecting pipe is passed through the inner hole of the sealing ring.

[0018] Optionally, each of the blades is arranged in a fan shape, and the arc of the fan is away from the shaft sleeve.

[0019] Optionally, the plurality of blades are arranged to be tilted clockwise or counterclockwise along the shaft sleeve, and the angle between each blade and the axis of the shaft sleeve is ∠A, 40°≤∠A≤50°.

[0020] Optionally, the shaft sleeve is provided with at least two second top screw holes, both of which extend in the radial direction of the shaft sleeve and are spaced apart in the radial direction of the shaft sleeve;

[0021] The stirring device further includes at least two second top screws, and the two second top screws are respectively installed in the two second top screw holes and are both in contact with the vent pipe.

[0022] Compared with the prior art, the technical solution of this application has the following beneficial technical effects:

[0023] As the stirring paddle rotates, gas flows from the vent tube through the connecting tube into the vent ring, ultimately entering the culture medium in the cell tank through the multiple through-holes. The vent ring rotates along with the stirring paddle, distributing bubbles more evenly throughout the culture medium, enabling better mixing and mass transfer. By integrating the vent tube with the stirring paddle, the stirring device occupies less space and is lighter. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 A schematic front view of a stirring device provided in an embodiment of the present invention;

[0025] Figure 2 for Figure 1 Schematic cross-sectional view along AA;

[0026] Figure 3 for Figure 2 An enlarged schematic diagram of the local A in the middle;

[0027] Figure 4 for Figure 2 An enlarged schematic diagram of the part B in the middle;

[0028] Figure 5 A schematic structural diagram of the stirring device provided by an embodiment of the present invention from another perspective;

[0029] Figure 6 A schematic structural diagram of the stirring device provided by an embodiment of the present invention from another perspective;

[0030] Figure 7 This is a bottom view schematic diagram of the stirring device provided in an embodiment of the present utility model.

[0031] In the accompanying drawings, the components represented by the reference numerals are as follows:

[0032] 1. Ventilation pipe; 11. Threaded hole; 2. Ventilation structure; 21. Connecting pipe; 22. Ventilation ring pipe; 221. Through hole; 23. Connecting piece; 231. Screw; 232. Bump; 2321. Step surface; 3. Agitator; 31. Bushing; 311. Second top screw hole; 32. Paddle; 4. Agitator shaft head; 41. First hole portion; 42. Second hole portion; 43. Third hole portion; 44. First top screw hole; 5. First top screw; 6. Sealing ring. DETAILED DESCRIPTION

[0033] To facilitate understanding of the present application, the present application will be described more fully below with reference to the accompanying drawings. The accompanying drawings provide embodiments of the present application. However, the present application may be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to make the disclosure of the present application more thorough and comprehensive.

[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application pertains. The terms used herein in the specification of this application are for the purpose of describing specific embodiments only and are not intended to limit this application.

[0035] It will be understood that spatial relational terms such as "under," "beneath," "below," "under," "above," "above," etc., may be used herein to describe the relationship of an element or feature shown in the figures to other elements or features. It will be understood that in addition to the orientations shown in the figures, spatial relational terms also include different orientations of the device in use and operation. For example, if the device in the drawings is turned over, the element or feature described as "under" or "beneath" or "beneath" the other elements will be oriented as "above" the other elements or features. Thus, the exemplary terms "under" and "under" may include both upper and lower orientations. In addition, the device may also include alternative orientations (e.g., rotated 90 degrees or other orientations), and the spatial descriptors used herein are interpreted accordingly.

[0036] It should be noted that when an element is considered to be "connected" to another element, it can be directly connected to the other element or connected to the other element through an intermediate element. In the following embodiments, "connection" should be understood as "electrical connection", "communication connection", etc., if the connected circuits, modules, units, etc. can transmit electrical signals or data to each other.

[0037] When used herein, the singular forms "a", "an", and "the" may also include the plural forms, unless the context clearly indicates otherwise. It should also be understood that the terms "include / comprise" or "have" and the like specify the presence of stated features, integers, steps, operations, components, parts, or combinations thereof, but do not preclude the possibility of the presence or addition of one or more other features, integers, steps, operations, components, parts, or combinations thereof.

[0038] Please refer to Figure 1 、 Figure 2 and Figure 6 The utility model proposes a stirring device, comprising: a ventilation pipe 1, a ventilation structure 2 and a stirring paddle 3, the upper end of the ventilation pipe 1 is used for ventilation and is used to be connected to a driving member; the ventilation structure 2 is connected to the lower end of the ventilation pipe 1, the ventilation structure 2 comprises a connecting pipe 21 connected to the lower end of the ventilation pipe 1 and a ventilation ring pipe 22 communicated with the connecting pipe 21, and the ventilation ring pipe 22 is provided with a plurality of through holes 221 distributed at intervals; the stirring paddle 3 comprises a shaft sleeve 31 and a plurality of blades 32, the shaft sleeve 31 surrounds the periphery of the ventilation pipe 1 and is arranged close to the ventilation ring pipe 22, and the plurality of blades 32 are distributed at intervals along the circumference of the shaft sleeve 31.

[0039] As the stirring paddle 3 rotates, gas flows from the vent tube 1 through the connecting tube 21 into the vent ring 22, and finally into the culture medium in the cell tank through the multiple through-holes 221. The vent ring 22 rotates along with the stirring paddle 3, distributing bubbles more evenly throughout the culture medium and improving mixing and mass transfer. By integrating the vent tube 1 with the stirring paddle 3, the space occupied by the stirring device is reduced, and its weight is reduced.

[0040] Specifically, the stirring device also includes a stirring shaft head 4, the inner hole of the stirring shaft head 4 is divided into a first hole portion 41, a second hole portion 42 and a third hole portion 43 which are connected in sequence along its axial direction. The first hole portion 41 is used for installing the driving shaft of the driving member, and the aperture of the second hole portion 42 is smaller than the second hole portion 42 and the third hole portion 43. The third mounting hole is used for the upper end of the ventilation pipe 1 to be inserted and then welded.

[0041] In this embodiment, referring to Figures 2 to 4 The drive shaft is set as a hollow shaft, the drive shaft is installed in the first hole portion 41, and the upper end of the ventilation pipe 1 is welded to the third hole portion 42, thereby connecting the drive shaft to the ventilation pipe 1, and the second hole portion 42 is connected to the inner hole of the drive shaft and the inner hole of the ventilation pipe 1, ensuring that the gas can flow smoothly from the drive shaft to the ventilation pipe 1.

[0042] In order to fix the driving shaft and the stirring shaft head 4, in this embodiment, refer to Figure 2 and Figure 3 The stirring shaft head 4 is further provided with a first jackscrew hole 44 extending radially therethrough, the first jackscrew hole 44 being connected to the first hole portion 41. The stirring device further includes a first jackscrew 5 which passes through the first jackscrew hole 44 to abut against the drive shaft. This provides a simple structure, easy installation, and a stable connection.

[0043] Furthermore, in this embodiment, referring to Figure 2 、 Figure 5 and Figure 7 The connecting tube 21 is curved, with one end connected to the lower end of the ventilation tube 1 and the other end welded to the inner side of the ventilation ring tube 22. This allows the ventilation ring tube 22 to form a passage with the ventilation tube 1, and the axis corresponding to the ring shape of the ventilation ring tube 22 coincides with the axis of the ventilation tube 1. As a result, the ventilation ring tube 22 rotates along its axis, making the bubbles emitted from the multiple through holes 221 more evenly distributed in the culture medium, thereby improving the efficiency of mixing and mass transfer.

[0044] In the present invention, the locations of the plurality of through holes 221 are not limited, as long as they are located on the ventilation ring tube 22. In this embodiment, the plurality of through holes 221 are located on the side of the ventilation ring tube 22 facing away from the ventilation tube 1. In another embodiment, the plurality of through holes 221 may also be located on the outer circumferential side or the inner circumferential side of the ventilation ring tube 22.

[0045] In order to connect the ventilation structure 2 and the ventilation pipe 1, in this embodiment, refer to Figure 2 、 Figure 4 and Figure 5 The lower portion of the inner hole of the vent pipe 1 is formed with a threaded hole 11. The vent structure 2 also includes a sleeve-shaped connector 23 comprising a screw 231 and a protrusion 232. The screw 231 is threaded into the threaded hole 11, and the end surface of the protrusion 232 facing the screw 231 is provided with a stepped surface 2321. The connecting pipe 21 is welded to the inner hole of the connector 23. The screw 231 is threaded into the threaded hole 11, thereby attaching the vent structure 2 to the vent pipe 1. This structure is simple and easy to disassemble and install for maintenance or replacement. The stepped surface 2321 abuts against the vent pipe 1, improving the sealing performance.

[0046] In order to ensure the airtightness of the ventilation structure 2 and the ventilation pipe 1, in this embodiment, Figure 2 and Figure 4 The stirring device further includes a sealing ring 6, which is disposed at the lower portion of the inner hole of the vent hole and abuts against the step surface 2321; the connecting pipe 21 is passed through the inner hole of the sealing ring 6.

[0047] Specifically, in this embodiment, referring to Figure 1 、 Figure 5 and Figure 6 , each of the blades 32 is arranged in a fan shape, and the arc of the fan is away from the shaft sleeve 31. In this way, the contact area between the blade 32 and the culture solution is large, and the stirring function is good.

[0048] Furthermore, the plurality of blades 32 are arranged counterclockwise along the shaft sleeve from top to bottom, and the angle between each blade 32 and the axis of the shaft sleeve 31 is ∠A, 40°≤∠A≤50°, thereby enhancing the stirring function and improving the stirring efficiency.

[0049] Specifically, continue to refer to Figure 1 、 Figure 5 and Figure 6 , in this embodiment, ∠A=45°.

[0050] In order to fix the stirring blade 3 to the vent hole, in this embodiment, refer to Figure 2 The shaft sleeve 31 is provided with at least two second jackscrew holes 311 extending radially from the shaft sleeve 31 and spaced apart along the radial direction of the shaft sleeve 31. The stirring device further includes at least two second jackscrews, each mounted in the second jackscrew holes 311 and abutting against the vent pipe 1. This provides a simple structure, a stable connection, and ease of installation.

[0051] The present invention further provides a cell culture reactor, comprising the stirring device. The stirring device is as described above, so the cell culture reactor includes all the technical features of the stirring device, which will not be described in detail here.

[0052] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A stirring device, characterized in that: include: A vent pipe, the upper end of which is used for ventilation and is connected to the driving member; a ventilation structure connected to the lower end of the ventilation pipe, the ventilation structure comprising a connecting pipe connected to the lower end of the ventilation pipe and a ventilation ring pipe communicating with the connecting pipe, the ventilation ring pipe being provided with a plurality of through holes distributed at intervals; and The stirring paddle comprises a shaft sleeve and a plurality of blades. The shaft sleeve surrounds the periphery of the ventilation pipe and is arranged close to the ventilation ring pipe. The plurality of blades are distributed at intervals along the circumference of the shaft sleeve on the periphery thereof.

2. The stirring device according to claim 1, characterized in that The stirring device also includes a stirring shaft head, the inner hole of the stirring shaft head is divided into a first hole portion, a second hole portion and a third hole portion which are connected in sequence along its axial direction, the first hole portion is used for installing the driving shaft of the driving member, the aperture of the second hole portion is smaller than the first hole portion and the third hole portion, and the third mounting hole is used for the upper end of the ventilation pipe to be inserted and then welded.

3. The stirring device according to claim 2, characterized in that The stirring shaft head is further provided with a first top screw hole extending in its radial direction, the first top screw hole being connected to the first hole portion; The stirring device further includes a first jackscrew, which passes through the first jackscrew hole to abut against the driving shaft.

4. The stirring device according to claim 1, characterized in that The connecting pipe is bent, and one end of the connecting pipe is connected to the lower end of the ventilation pipe, and the other end is welded to the inner side of the ventilation ring pipe, so that the ventilation ring pipe and the ventilation pipe form a passage and are coaxially arranged.

5. The stirring device according to claim 1, characterized in that A threaded hole is formed at the lower portion of the inner hole of the vent pipe; The ventilation structure further includes a sleeve-shaped connecting piece, the connecting piece including a screw and a protrusion connected to each other, the screw being screwed into the threaded hole, and the end surface of the protrusion facing the screw being a stepped surface; The connecting pipe is welded in the inner hole of the connecting piece.

6. The stirring device according to claim 5, characterized in that The stirring device further includes a sealing ring, which is provided at the lower portion of the inner hole of the vent hole and abuts against the step surface; The connecting pipe is passed through the inner hole of the sealing ring.

7. The stirring device according to claim 1, characterized in that Each of the blades is arranged in a fan shape, and the arc of the fan is away from the shaft sleeve.

8. The stirring device according to claim 1, characterized in that The plurality of blades are arranged to be tilted clockwise or counterclockwise along the shaft sleeve, and the angle between each blade and the axis of the shaft sleeve is ∠A, 40°≤∠A≤50°.

9. The stirring device according to claim 1, characterized in that The shaft sleeve is provided with at least two second top screw holes, both of which extend in the radial direction of the shaft sleeve and are spaced apart in the radial direction of the shaft sleeve; The stirring device further includes at least two second top screws, and the two second top screws are respectively installed in the two second top screw holes and are both in contact with the vent pipe.

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