Urethra sling

Abstract

The utility model provides a urethra sling, and relates to the technical field of biomedical materials. The urethra sling comprises a polymer woven mesh and biological material sheets, and the biological material sheets are fixed to the two opposite side faces of the polymer woven mesh. The composite material not only has relatively good biocompatibility, but also has relatively good mechanical properties.

Description

Technical Field

[0001] The present application relates to the technical field of biomedical materials, and in particular to a urethral sling. Background Art

[0002] Stress urinary incontinence (SUI) is the involuntary leakage of urine from the urethra when abdominal pressure is increased, such as during coughing or sneezing. Symptoms include involuntary urine leakage during coughing, sneezing, laughing, and other events that increase abdominal pressure. Currently, a sling made of a woven polymer mesh implanted in the mid-urethra is a common surgical treatment for moderate to severe SUI.

[0003] However, the polymer woven mesh used as the suspension sling has a rough surface, poor conformity to the implantation site, and poor biocompatibility of the polymer material. Utility Model Content

[0004] The present application provides a urethral sling, which not only has good biocompatibility but also has good mechanical properties.

[0005] This application is implemented as follows:

[0006] The present application provides a urethral sling, which includes: a polymer woven mesh and a biomaterial sheet, wherein the biomaterial sheet is fixed to two opposite sides of the polymer woven mesh.

[0007] In a possible embodiment, the biomaterial sheet is fixed to the polymer woven mesh by bonding or suturing.

[0008] In a possible embodiment, the biomaterial sheet is sutured and fixed to the polymer woven mesh, and the edge of the polymer woven mesh is sutured to the biomaterial sheet.

[0009] In one possible embodiment, the biomaterial sheet includes a first area that completely covers the polymer woven mesh and a second area extending along the edge of the polymer woven mesh. The edge of the polymer woven mesh and the first area of ​​the biomaterial sheet are sutured with a first suture line, and the second areas of the biomaterial sheet on opposite sides of the polymer woven mesh are sutured with a second suture line.

[0010] In one possible embodiment, the second suture line surrounds the first suture line, and the distance between the second suture line and the first suture line is 0.1-3 mm.

[0011] In one possible embodiment, the biomaterial sheet has a plurality of through holes.

[0012] In a possible embodiment, the polymer woven mesh has a plurality of meshes, and one of the meshes is connected to at least one of the through holes of the biomaterial sheet.

[0013] In a possible implementation manner, the through hole has a diameter of 0.1-1 mm.

[0014] In one possible embodiment, the biomaterial sheet is acellular small intestinal submucosa or acellular dermal matrix.

[0015] In one possible embodiment, the polymer woven mesh is a polypropylene woven mesh or a polyethylene woven mesh.

[0016] This application has at least the following beneficial effects:

[0017] In the urethral sling of this application, biomaterial sheets are fixed to opposite sides of a polymer woven mesh. This prevents direct contact between the biomaterial sheets and the tissue at the implantation site, improving the biocompatibility of the urethral sling. The presence of the polymer woven mesh also ensures the mechanical properties of the urethral sling compared to a single biomaterial sheet. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 This is a schematic structural diagram of a urethral sling according to an embodiment of the present application;

[0020] Figure 2 A cross-sectional view of a urethral sling according to an embodiment of the present application;

[0021] Figure 3 A schematic diagram of a biomaterial sheet according to an embodiment of the present application;

[0022] Figure 4 Schematic diagram of a polymer woven mesh according to an embodiment of the present application.

[0023] Icons: 10 - urethral sling; 11 - polymer woven mesh; 111 - mesh; 12 - biomaterial sheet; 121 - first region; 122 - second region; 123 - through hole; 131 - first suture line; 132 - second suture line. DETAILED DESCRIPTION

[0024] To make the objectives, technical solutions, and advantages of the embodiments of the present application more clear, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Generally, the components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations.

[0025] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for protection, but merely represents selected embodiments of the present application. All other embodiments obtained by persons of ordinary skill in the art based on the embodiments in the present application without creative work are within the scope of protection of the present application.

[0026] In the description of this application, it should be noted that the terms "upper," "lower," "inner," and "outer" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships in which the product of this application is typically placed when in use. These terms are intended solely to facilitate the description of this application and simplify the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," and "third," etc., are used solely to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0027] It should also be noted that, in the description of this application, unless otherwise expressly specified or limited, the terms "disposed," "installed," and "connected" should be understood broadly. For example, they may refer to fixed connections, detachable connections, or integral connections; they may refer to direct connections, indirect connections through an intermediate medium, or internal connections between two components. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances. Example

[0028] The present application embodiment provides a urethral sling 10, please refer to Figure 1 and Figure 2 , which includes a polymer woven mesh 11 and a biomaterial sheet 12 , wherein the biomaterial sheet 12 is fixed to two opposite sides of the polymer woven mesh 11 , that is, two opposite sides of the polymer woven mesh 11 are provided with biomaterial sheets 12 .

[0029] In the urethral sling 10 of the present embodiment, the biomaterial sheet 12 is fixed to opposite sides of the polymer woven mesh 11. Direct contact between the biomaterial sheet 12 and the tissue at the implantation site is avoided, thereby improving the biocompatibility of the urethral sling 10. Furthermore, compared to a single biomaterial sheet 12, the urethral sling 10 of the present embodiment is able to maintain its mechanical properties due to the presence of the polymer woven mesh 11.

[0030] Biomaterial sheet 12 is a decellularized intestinal submucosa or acellular dermal matrix. Because the decellularization process removes cells and other antigenic molecules in the tissue that could cause rejection, it exhibits improved biocompatibility. Furthermore, the surface of biomaterial sheet 12 is smoother than that of polymer woven mesh 11, and its inherent extracellular matrix structure provides a favorable microenvironment for cell growth and climbing. Alternatively, polymer woven mesh 11 may be a polypropylene or polyethylene woven mesh.

[0031] The biomaterial sheet 12 and the polymer woven mesh 11 are fixed by bonding or suturing. When the biomaterial sheet 12 and the polymer woven mesh 11 are fixed by suturing, the edge of the polymer woven mesh 11 is sutured with the biomaterial sheet 12, that is, the suture is formed along the edge of the polymer woven mesh 11, and a ring is formed. This method can make the polymer woven mesh 11 and the biomaterial sheet 12 have more connection points, so that the connection between the polymer woven mesh 11 and the biomaterial sheet 12 is more stable. In other embodiments, the middle area of ​​the polymer woven mesh 11 can also be sutured with the biomaterial sheet 12. The suture line can be a collagen line, the main component of which is collagen and has high biocompatibility. The suture line can also be a medical polymer suture line, such as a polyester line, a polyamide line or a polyamide silk line.

[0032] Exemplarily, the biomaterial sheet 12 includes a first region 121 that completely covers the polymer woven mesh 11 and a second region 122 that extends along the edge of the polymer woven mesh 11. That is, within the first region 121 of the biomaterial sheet 12, there is a polymer woven mesh 11 between the two biomaterial sheets 12, while within the second region 122 of the biomaterial sheet 12, there is no polymer woven mesh 11 between the two biomaterial sheets 12, and the two biomaterial sheets 12 are tightly attached to each other.

[0033] The edges of the polymer woven mesh 11 are sutured to the first region 121 of the biomaterial sheet 12 by first sutures 131, and the second regions 122 of the biomaterial sheet 12 on opposite sides of the polymer woven mesh 11 are sutured by second sutures 132. The second sutures 132 sew the second regions 122 of the biomaterial sheet 12 together, so that the polymer woven mesh 11 can be better enclosed between the biomaterial sheets 12, making it less likely to come into direct contact with the tissue at the implantation site, thereby improving safety.

[0034] The second suture 132 surrounds the first suture 131, and the distance between the second suture 132 and the first suture 131 is 0.1-3 mm. For example, the distance between the second suture 132 and the first suture 131 is any one of 0.1 mm, 0.5 mm, 1 mm, 1.5 mm, 2 mm, 2.5 mm, and 3 mm, or a value between any two of them.

[0035] In some embodiments, the biomaterial sheet 12 has a plurality of through holes 123 (see Figure 3 The biomaterial sheet 12 is in direct contact with the tissue at the implant site. The through-holes 123 of the biomaterial sheet 12 facilitate tissue and cell growth into the urethral sling 10, playing an important role in repair. Optionally, the through-holes 123 have a diameter of 0.1 to 1 mm, such as any one of 0.3 mm, 0.5 mm, 0.7 mm, 0.8 mm, and 1 mm, or any value in between.

[0036] In addition, the polymer woven mesh 11 has a plurality of meshes 111 (see Figure 4 ), one mesh 111 of the biomaterial sheet 12 is connected to at least one through-hole 123. Since the through-hole 123 is connected to the mesh 111 of the polymer woven mesh 11, it is conducive to the growth of tissues and cells through the through-hole 123 of the biomaterial sheet 12 into the mesh 111 of the polymer woven mesh 11, and then through the mesh 111 into the through-hole 123 of the biomaterial sheet 12 on the other side of the polymer woven mesh 11, thereby allowing tissues and cells to grow better into the urethral sling 10, achieving a better repair effect.

[0037] In summary, in the urethral sling 10 of the present application, the biomaterial sheet 12 is fixed to two opposite sides of the polymer woven mesh 11. The biomaterial sheet 12 is in direct contact with the tissue at the implantation site, thereby preventing direct contact between the polymer woven mesh 11 and the implantation site tissue, thereby improving the biocompatibility of the urethral sling 10. Furthermore, the presence of the polymer woven mesh 11, compared to a single biomaterial sheet 12, can ensure the mechanical properties of the urethral sling 10.

[0038] The above are merely preferred embodiments of the present application and are not intended to limit the present application. Those skilled in the art will readily appreciate that various modifications and variations are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.

Claims

1. A urethral sling, characterized in that: It includes: Polymer woven mesh, and Biomaterial sheets are fixed to two opposite sides of the polymer woven mesh.

2. The urethral sling according to claim 1, characterized in that The biomaterial sheet and the polymer woven mesh are fixed by bonding or suturing.

3. The urethral sling according to claim 2, characterized in that The biomaterial sheet is sutured and fixed to the polymer woven mesh, and the edge of the polymer woven mesh is sutured to the biomaterial sheet.

4. The urethral sling according to claim 3, characterized in that The biomaterial sheet includes a first area that completely covers the polymer woven mesh and a second area extending along the edge of the polymer woven mesh. The edge of the polymer woven mesh and the first area of ​​the biomaterial sheet are sutured with a first suture line, and the second areas of the biomaterial sheet on opposite sides of the polymer woven mesh are sutured with a second suture line.

5. The urethral sling according to claim 4, characterized in that The second suture line surrounds the first suture line, and a distance between the second suture line and the first suture line is 0.1-3 mm.

6. The urethral sling according to any one of claims 1 to 5, characterized in that: The biomaterial sheet has a plurality of through holes.

7. The urethral sling according to claim 6, characterized in that The polymer woven mesh has a plurality of meshes, and one of the meshes is connected to at least one through-hole of the biomaterial sheet.

8. The urethral sling according to claim 6, characterized in that The through hole has a diameter of 0.1-1 mm.

9. The urethral sling according to any one of claims 1 to 5, characterized in that: The biomaterial sheet is acellular intestinal submucosa or acellular dermal matrix.

10. The urethral sling according to any one of claims 1 to 5, characterized in that: The polymer woven mesh is a polypropylene woven mesh or a polyethylene woven mesh.

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