Heparin sodium concentration device

Abstract

The utility model discloses a heparin sodium concentration device, which relates to the technical field of heparin sodium production and comprises a filter box and a concentration box, a plurality of heating plates are fixed in the concentration box along the height direction of the concentration box, the concentration box is divided into a plurality of independent concentration cavities by the plurality of heating plates, and electric heating wires are arranged in the heating plates. A conveying pipe is arranged between the filtering box and the concentration box, one end of the conveying pipe is connected with the bottom of the filtering box, each concentration cavity is connected with a branch pipe, the branch pipe is connected with the other end of the conveying pipe, an impurity filtering plate is arranged in the filtering box, impurities in the heparin sodium eluent are filtered out through the filtering box, and the quality of the heparin sodium eluent is improved; the heparin sodium eluent is injected into the plurality of concentration cavities through the plurality of branch pipes, so that the concentration box is divided into the plurality of concentration cavities with smaller volumes, and the problem of uneven heating caused by overlarge heparin sodium eluent accumulation and submission is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of heparin sodium production, in particular to a heparin sodium concentration device. Background Art

[0002] Sodium heparin is widely used clinically for preventing thrombosis and embolism, treating disseminated intravascular coagulation (DIC) caused by various causes, and for in vitro and in vivo anticoagulation. Heparin sodium eluate is often concentrated by heating to separate water from the solution, facilitating subsequent freeze-drying. Currently, sodium heparin eluate is accumulated in a concentration tank for heating and concentration. Due to the large volume of the accumulated sodium heparin eluate, the heated solution is unevenly heated, resulting in slow concentration efficiency and poor quality after concentration. Utility Model Content

[0003] The purpose of the utility model is to overcome the deficiencies of the prior art and provide a heparin sodium concentration device to solve the deficiencies of the prior art.

[0004] The purpose of the utility model is achieved through the following technical solutions: a heparin sodium concentrator, comprising a filter box and a concentrating box, wherein a plurality of heating plates are fixed in the concentrating box along its own height direction, and the plurality of heating plates divide the concentrating box into a plurality of independent concentrating chambers, and an electric heating wire is provided in the heating plate, and a delivery pipe is provided between the filter box and the concentrating box, one end of the delivery pipe is connected to the bottom of the filter box, and each of the concentrating chambers is connected to a branch pipe, and the branch pipe is connected to the other end of the delivery pipe, and an impurity filter plate is provided in the filter box.

[0005] Furthermore, the mesh of the impurity filter plate is larger than the heparin sodium molecules and water molecules.

[0006] Furthermore, a collection net is laid on the impurity filtering plate.

[0007] Furthermore, the top of the filter box is open, a box cover is hinged on the top of the filter box, a hook is fixed to the bottom of the box cover, and both ends of the collection net are connected with a pull rope, and the pull rope is wrapped around the hook.

[0008] Furthermore, an annular mounting platform is fixed in the filter box, and the impurity filtering plate is mounted on the annular mounting platform by screws.

[0009] Furthermore, a disassembly window is provided on the side wall of the filter box, and a sealing plate is detachably connected to the disassembly window.

[0010] Furthermore, an annular sealing platform is fixed in the disassembly window, and a sealing ring is provided at one end of the annular sealing platform close to the sealing plate. The sealing plate squeezes the sealing ring to produce deformation, and the sealing plate is connected to the annular sealing platform by screws.

[0011] Furthermore, a plurality of vibrators are installed on the side wall of the concentration tank.

[0012] Furthermore, each of the concentration chambers is connected to an exhaust pipe, and a conical plug is provided at one end of the exhaust pipe away from the concentration tank. A mounting plate is fixed to the end of the conical plug away from the exhaust pipe. A shaft shoulder is fixed on the exhaust pipe, and a spring is provided on the exhaust pipe. Both ends of the spring are respectively connected to the mounting plate and the shaft shoulder. When the spring is in normal state, the conical plug blocks the exhaust pipe.

[0013] The beneficial effects of the utility model are:

[0014] Impurities in the sodium heparin eluate are filtered out by the filter box to improve the quality of the sodium heparin eluate. The sodium heparin eluate is injected into multiple concentration chambers through multiple branch pipes, thereby dividing the concentration box into multiple smaller concentration chambers to avoid the problem of uneven heating caused by excessive accumulation of sodium heparin eluate. At the same time, the sodium heparin eluate in the concentration chamber has two upper and lower heating surfaces, which increases the heating area and improves the concentration efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of the internal structure of a heparin sodium concentration device of the present utility model;

[0016] Figure 2 for Figure 1 Enlarged view of point A in the middle;

[0017] Figure 3 for Figure 1 Enlarged view of point B in the middle;

[0018] In the figure, 1-filter box, 2-concentration box, 3-heating plate, 4-concentration chamber, 5-electric heating wire, 6-delivery pipe, 7-branch pipe, 8-impurity filter plate, 10-collection net, 11-box cover, 12-hook, 13-pull rope, 14-annular mounting platform, 15-disassembly window, 16-sealing plate, 17-annular sealing platform, 18-sealing ring, 19-vibrator, 20-exhaust pipe, 21-conical plug, 22-mounting plate, 23-shaft shoulder, 24-spring. DETAILED DESCRIPTION

[0019] Example 1

[0020] like Figures 1 to 3As shown, a sodium heparin concentrator comprises a filter box 1 and a concentrator box 2. Multiple heating plates 3 are fixed along the height of the concentrator box 2. The multiple heating plates 3 divide the concentrator box 2 into multiple independent concentrating chambers 4. Electric heating wires 5 are installed in the heating plates 3. A delivery pipe 6 is provided between the filter box 1 and the concentrator box 2. One end of the delivery pipe 6 is connected to the bottom of the filter box 1. Each concentrating chamber 4 is connected to a branch pipe 7, which is connected to the other end of the delivery pipe 6. An impurity filter plate 8 is provided in the filter box 1. Impurities in the sodium heparin eluate are filtered through the filter box 1 to improve the quality of the sodium heparin eluate. The sodium heparin eluate is injected into the multiple concentrating chambers 4 through the multiple branch pipes 7, thereby dividing the concentrator box 2 into multiple smaller concentrating chambers 4 and preventing the problem of uneven heating caused by excessive accumulation of the sodium heparin eluate. Electric heating wires are installed in the top and bottom walls of the concentrator box 2, so that the sodium heparin eluate in each concentrating chamber 4 has two heating surfaces, upper and lower, increasing the heating area and improving the concentration efficiency.

[0021] Furthermore, a plurality of vibrators 19 are installed on the side wall of the concentration box 2, which vibrate the concentration box 2 to enhance the movement intensity of the sodium heparin eluate in the concentration chamber 4, making the heating more uniform and further improving the concentration effect.

[0022] Example 2

[0023] Based on the first embodiment, Figure 1 and Figure 3 As shown, each concentration chamber 4 is connected to an exhaust pipe 20, and a conical plug 21 is provided at one end of the exhaust pipe 20 away from the concentration tank 2. A mounting plate 22 is fixed to the end of the conical plug 21 away from the exhaust pipe 20. A shaft shoulder 23 is fixed on the exhaust pipe 20, and a spring 24 is provided on the exhaust pipe 20. The two ends of the spring 24 are respectively connected to the mounting plate 22 and the shaft shoulder 23. When the spring 24 is in normal state, the conical plug 21 blocks the exhaust pipe 20, and the water vapor generated by the concentration is discharged through the exhaust pipe 20 , so that the sodium heparin eluate is gradually concentrated and dried. In order to avoid heat dissipation, a conical plug 21 is provided. When the pressure in the concentrating chamber 4 is greater than the force of the spring 24, the conical plug 21 is pushed away from the exhaust pipe 20, so that the exhaust pipe 20 is separated from the conical plug 21, and the water vapor is discharged smoothly. When the pressure in the concentrating chamber 4 is less than the force of the spring 24, the exhaust pipe 20 is in a blocked state under the action of the spring 24, thereby reducing the temperature loss in the concentrating chamber 4 and improving the concentration efficiency.

[0024] Example 3

[0025] Based on the second embodiment, Figure 1As shown, the mesh of the impurity filter plate 8 is larger than the sodium heparin molecules and water molecules, and a collecting net 10 is laid on the impurity filter plate 8. The top of the filter box 1 is open, and a box cover 11 is hinged on the top of the filter box 1. A hook 12 is fixed to the bottom of the box cover 11. Both ends of the collecting net 10 are connected to a pull rope 13, and the pull rope 13 is wrapped around the hook 12. In order to facilitate the cleaning of impurities on the impurity filter plate 8, a collecting net 10 is laid on the impurity filter plate 8, and the sodium heparin eluate falls on the collecting net 10, and the filtered impurities remain on the collecting net 10. The box cover 11 is opened regularly, and the collecting net 10 is taken out of the filter box 1 by the pull rope 13. After cleaning the impurities in the collecting net 10, it is installed in the filter box 1, thereby facilitating the cleaning of impurities.

[0026] Example 4

[0027] Based on the third embodiment, Figure 1 and Figure 2 As shown, an annular mounting platform 14 is fixed in the filter box 1, and the impurity filter plate 8 is installed on the annular mounting platform 14 by screws. A disassembly window 15 is opened on the side wall of the filter box 1, and a sealing plate 16 is detachably connected to the disassembly window 15. After long-term operation, the impurity filter plate 8 will be blocked. In order to facilitate the cleaning or replacement of the impurity filter plate 8, the impurity filter plate 8 is set to a detachable structure. By removing the sealing plate 16, the impurity filter plate 8 can be installed and disassembled through the disassembly window 15, and the operation is simple and quick.

[0028] Furthermore, an annular sealing platform 17 is fixed in the disassembly window 15, and a sealing ring 18 is provided at one end of the annular sealing platform 17 close to the sealing plate 16. The sealing plate 16 squeezes the sealing ring 18 to cause deformation, and the sealing plate 16 is connected to the annular sealing platform 17 by screws. The sealing ring 18 eliminates the gap between the sealing plate 16 and the annular sealing platform 17, thereby improving the sealing performance and preventing liquid in the filter box 1 from leaking.

Claims

1. A heparin sodium concentration device, characterized in that: The invention comprises a filter box (1) and a concentration box (2), wherein a plurality of heating plates (3) are fixed in the concentration box (2) along its own height direction, and the plurality of heating plates (3) divide the concentration box (2) into a plurality of independent concentration chambers (4), and an electric heating wire (5) is provided in the heating plate (3). A delivery pipe (6) is provided between the filter box (1) and the concentration box (2), and one end of the delivery pipe (6) is connected to the bottom of the filter box (1), and each of the concentration chambers (4) is connected to a branch pipe (7), and the branch pipe (7) is connected to the other end of the delivery pipe (6). An impurity filter plate (8) is provided in the filter box (1).

2. A heparin sodium concentration device according to claim 1, characterized in that: The mesh of the impurity filter plate (8) is larger than the heparin sodium molecules and water molecules.

3. A heparin sodium concentration device according to claim 2, characterized in that: A collection net (10) is laid on the impurity filter plate (8).

4. A heparin sodium concentration device according to claim 3, characterized in that: The top of the filter box (1) is open, a box cover (11) is hinged on the top of the filter box (1), a hook (12) is fixed to the bottom of the box cover (11), and both ends of the collection net (10) are connected to a drawstring (13), and the drawstring (13) is wrapped around the hook (12).

5. The heparin sodium concentration device according to claim 1, characterized in that: An annular mounting platform (14) is fixed in the filter box (1), and the impurity filter plate (8) is mounted on the annular mounting platform (14) by means of screws.

6. A heparin sodium concentration device according to claim 5, characterized in that: A disassembly window (15) is provided on the side wall of the filter box (1), and a sealing plate (16) is detachably connected to the disassembly window (15).

7. A heparin sodium concentration device according to claim 6, characterized in that: An annular sealing platform (17) is fixed in the disassembly window (15), and a sealing ring (18) is provided at one end of the annular sealing platform (17) close to the sealing plate (16). The sealing plate (16) squeezes the sealing ring (18) to produce deformation, and the sealing plate (16) is connected to the annular sealing platform (17) by screws.

8. The heparin sodium concentration device according to claim 1, characterized in that: A plurality of vibrators (19) are installed on the side wall of the concentration tank (2).

9. The heparin sodium concentration device according to claim 1, characterized in that: Each of the concentration chambers (4) is connected to an exhaust pipe (20), and a conical plug (21) is provided at one end of the exhaust pipe (20) away from the concentration tank (2), and a mounting plate (22) is fixed to the end of the conical plug (21) away from the exhaust pipe (20), and a shaft shoulder (23) is fixedly provided on the exhaust pipe (20), and a spring (24) is provided on the exhaust pipe (20), and two ends of the spring (24) are respectively connected to the mounting plate (22) and the shaft shoulder (23), and when the spring (24) is in a normal state, the conical plug (21) blocks the exhaust pipe (20).

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