Collecting and extracting device

Abstract

The utility model relates to the technical field of cell collection, in particular to a collection and extraction device which comprises a centrifugal extraction module and a collection module, a centrifugal turntable and a motor for driving the centrifugal turntable to rotate are arranged in the centrifugal extraction module, and a fixing hole is formed in the upper side of the centrifugal turntable; a vacuum pump is arranged in the collecting module and connected with a collecting needle through an exhaust pipe, the interior of the collecting needle is divided into an exhaust cavity and a collecting cavity through an elastic diaphragm, the exhaust pipe is communicated with the exhaust cavity, and a collecting nozzle communicated with the collecting cavity is arranged at the end of the collecting needle. By arranging the centrifugal rotating disc and the motor, after cell samples are collected, the cell samples are put into the fixing holes to be centrifuged, so that separation and extraction of the cell samples are achieved, and the problems that in the prior art, some devices can only conduct simple cell collection, but do not have effective separation and purification functions are solved.

Description

Technical Field

[0001] The utility model relates to the technical field of cell collection, in particular to a collection and extraction device. Background Art

[0002] In today's biomedical field, cell research is becoming increasingly important. As the fundamental unit of life, the study of cells is crucial for understanding physiological and pathological processes, disease diagnosis and treatment, drug development, and regenerative medicine. Among the many steps in cell research and application, cell collection and extraction are fundamental and crucial steps.

[0003] Many existing cell collection and extraction devices have a single function and cannot meet the needs of complex experiments. For example, some devices can only perform simple cell collection but lack effective separation and purification functions.

[0004] At the same time, existing devices need to be improved in terms of operational convenience and automation. The complex operating procedures not only increase the workload of experimenters, but also easily introduce human errors, affecting the accuracy and reliability of experimental results.

[0005] In view of the above situation, in order to meet the demand for high-quality cell collection and extraction in the biomedical field and promote the development of cell research and related applications, it is urgent to develop a cell collection and extraction device with complete functions and easy operation. Utility Model Content

[0006] The purpose of the utility model is to provide a collection and extraction device to solve the problem in the prior art that some devices can only perform simple cell collection but lack effective separation and purification functions.

[0007] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0008] A collection and extraction device includes a centrifugal extraction module and a collection module. The centrifugal extraction module is provided with a centrifugal turntable and a motor for driving the centrifugal turntable to rotate, and a fixing hole is provided on the upper side of the centrifugal turntable; a vacuum pump is provided in the collection module, and the vacuum pump is connected to a collection needle through an exhaust pipe. The collection needle is separated by an elastic diaphragm to form an exhaust chamber and a collection chamber, the exhaust pipe is connected to the exhaust chamber, and the end of the collection needle is provided with a collection nozzle connected to the collection chamber.

[0009] A further technical solution is that the collection needle includes an air extraction section, a diaphragm section and a collection section which are connected in sequence, and the air extraction section, the diaphragm section and the collection section are all tubular; the upper end of the air extraction section is closed, and the end is connected to the air extraction pipe, the lower end of the air extraction section and the upper end of the diaphragm section are detachably connected, the edge of the elastic diaphragm is connected to the inner wall of the diaphragm section, and the lower end of the diaphragm section and the upper end of the collection section are detachably connected; the collection nozzle is placed at the lower end of the collection section.

[0010] A further technical solution is that a switch for controlling the start and stop of the vacuum pump is installed on the outer wall of the air extraction section.

[0011] A further technical solution is that the collection nozzle is detachably connected to a needle or a sealing cover.

[0012] A further technical solution is that a first thread is provided on the outer wall surrounding the lower end of the exhaust section, a second thread is provided on the inner wall surrounding the upper end of the diaphragm section, and the first thread is thread-matched and connected to the second thread; a third thread is provided on the outer wall surrounding the lower end of the diaphragm section, a fourth thread is provided on the inner wall surrounding the upper end of the collection section, and the third thread and the fourth thread are thread-matched and connected to each other.

[0013] A further technical solution is that a placement hole for placing the collection needle is provided on the upper side of the collection module.

[0014] A further technical solution is that a first drawer and a second drawer arranged up and down are provided on the side of the collection module.

[0015] A further technical solution is that a rotating groove is provided in the upper side depression of the centrifugal extraction module, and a driving cavity is provided correspondingly below the rotating groove of the centrifugal extraction module. A driving hole connected to the driving cavity is provided at the bottom of the rotating groove, and a driving rod is rotatably provided in the driving hole. The upper end of the driving rod is connected to the lower side of the centrifugal turntable, the motor is provided in the driving cavity, and the output shaft and the lower end of the driving rod are coaxially connected.

[0016] Compared with the prior art, the present invention has at least one of the following beneficial effects: 1. When collecting cell samples, the air in the suction chamber of the collection needle is extracted by a vacuum pump, the air pressure in the suction chamber is reduced, and the elastic diaphragm is bulged toward the suction chamber, thereby generating negative pressure in the collection chamber, and then the cell sample is collected with the help of the collection nozzle. In this way, when collecting cell samples, electric operation is adopted to improve the traditional manual syringe extraction, and the operation is more convenient; 2. By setting a centrifugal turntable and a motor, after the cell sample is collected, it is placed in the fixed hole for centrifugation to achieve separation and extraction of the cell sample, solving the problem in the prior art that some devices can only perform simple cell collection but lack effective separation and purification functions. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1It is an overall schematic diagram of a collection and extraction device of the present utility model.

[0018] Figure 2 This is a schematic diagram of a driving chamber of a collection and extraction device of the present utility model.

[0019] Figure 3 This is a schematic diagram of the cooperation between a collection needle and a sealing cover of a collection and extraction device of the present invention.

[0020] Figure 4 This is a schematic diagram of the cooperation between a collection needle and a needle head of a collection and extraction device of the present invention.

[0021] Icon: 1- centrifugal extraction module, 2- collection module, 3- centrifugal turntable, 4- motor, 5- exhaust tube, 6- collection needle, 7- elastic diaphragm, 8- exhaust chamber, 9- collection chamber, 10- collection nozzle, 11- exhaust section, 12- diaphragm section, 13- collection section, 14- switch, 15- needle, 16- sealing cover, 17- placement hole, 18- first drawer, 19- second drawer, 20- rotating slot, 21- driving chamber. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0023] Figures 1 to 4 Shown is an embodiment of the present utility model.

[0024] Example:

[0025] A collection and extraction device includes a centrifugal extraction module 1 and a collection module 2. The centrifugal extraction module 1 is provided with a centrifugal turntable 3 and a motor 4 for driving the centrifugal turntable 3 to rotate. The centrifugal turntable 3 has a fixing hole on its upper side. The collection module 2 is provided with a vacuum pump, which is connected to a collection needle 6 via an exhaust pipe 5. The collection needle 6 is separated into an exhaust chamber 8 and a collection chamber 9 by an elastic diaphragm 7. The exhaust pipe 5 is connected to the exhaust chamber 8. The end of the collection needle 6 is provided with a collection nozzle 10 connected to the collection chamber 9. When collecting a cell sample, the vacuum pump extracts air from the exhaust chamber 8 of the collection needle 6, reducing the air pressure in the exhaust chamber 8 and causing the elastic diaphragm 7 to bulge toward the exhaust chamber 8, thereby generating a negative pressure in the collection chamber 9. The cell sample is then collected using the collection nozzle 10. In this way, when collecting the cell sample, electric operation is adopted, improving the traditional manual syringe extraction and making the operation more convenient. By providing a centrifugal turntable 3 and a motor 4, after the cell sample is collected, it is placed in the fixed hole for centrifugation to achieve separation and extraction of the cell sample, thereby resolving the problem in the prior art that some devices can only perform simple cell collection but lack effective separation and purification functions. The elastic diaphragm 7 can be made of medical grade silicone.

[0026] The collection needle 6 includes an air extraction section 11, a diaphragm section 12 and a collection section 13 connected in sequence, and the air extraction section 11, the diaphragm section 12 and the collection section 13 are all tubular; the upper end of the air extraction section 11 is closed, and the end is connected to the air extraction pipe 5, the lower end of the air extraction section 11 and the upper end of the diaphragm section 12 are detachably connected, the edge of the elastic diaphragm 7 is connected to the inner wall of the diaphragm section 12, and the lower end of the diaphragm section 12 and the upper end of the collection section 13 are detachably connected; the collection nozzle 10 is placed at the lower end of the collection section 13.

[0027] A switch 14 for controlling the start and stop of the vacuum pump is installed on the outer wall of the vacuum section 11.

[0028] The collection nozzle 10 is detachably connected to a needle 15 or a sealing cover 16 .

[0029] A first thread is provided on the outer wall surrounding the lower end of the vacuum section 11, and a second thread is provided on the inner wall surrounding the upper end of the diaphragm section 12, wherein the first thread and the second thread are threadedly connected. A third thread is provided on the outer wall surrounding the lower end of the diaphragm section 12, and a fourth thread is provided on the inner wall surrounding the upper end of the collection section 13, wherein the third thread and the fourth thread are threadedly connected. With this arrangement, when collecting a cell sample, by installing the needle 15 on the collection nozzle 10 and aligning it with the cell sample, the vacuum pump is started by the switch 14. The vacuum pump starts to draw the cell sample into the collection section 13 through the needle 15. After the extraction is completed, the needle 15 is removed, the sealing cap 16 is closed on the collection nozzle 10, and then the switch 14 is turned off to stop the vacuum pump. This can prevent the elastic diaphragm 7 from elastically recovering when the vacuum pump is turned off and pushing out the cell sample. After turning off the vacuum pump, grip the diaphragm section 12 and the vacuum section 11 and rotate them to remove the diaphragm section 12 from the vacuum section 11. At this point, loosen the connection between the diaphragm section 12 and the collection section 13 to release excess gas within the collection section 13, and then tighten the collection section 13 and the diaphragm section 12 again. The collection section 13 and the diaphragm section 12 are then placed together in the fixed hole of the centrifugal turntable 3 and centrifuged. After centrifugation, the cell fluid within the collection section 13 needs to be filtered through a filtration device. During filtration, align the filter screen, first remove the sealing cap 16, and then loosen the connection between the diaphragm section 12 and the collection section 13. The separated cell sample within the collection section 13 will flow through the collection nozzle 10 onto the filter screen. This arrangement utilizes the collection section 13 and the diaphragm section 12 in conjunction with each other to replace the test tube for centrifugation, eliminating the need to place the cell sample within the collection needle 6 into a test tube before centrifugation, as is conventional practice.

[0030] The upper side of the collection module 2 is provided with a placement hole 17 for placing the collection needle 6. The placement hole 17 is provided to facilitate the fixing of the collection needle 6 in normal times.

[0031] The side of the collection module 2 is provided with a first drawer 18 and a second drawer 19 arranged in an upper and lower arrangement. The first drawer 18 can store clean collection segments 13, diaphragm segments 12, needles 15, and sealing caps 16. The second drawer 19 is used to store used collection segments 13, diaphragm segments 12, needles 15, and sealing caps 16. The collection segments 13 and diaphragm segments 12 can be recycled, disinfected, and reused, or they can be used once.

[0032] A rotating groove 20 is recessed on the upper side of the centrifugal extraction module 1. A drive cavity 21 is correspondingly provided below the rotating groove 20. A drive hole is provided at the bottom of the rotating groove 20 and is connected to the drive cavity 21. A drive rod is rotatably provided in the drive hole. The upper end of the drive rod is connected to the lower side of the centrifugal turntable 3. The motor 4 is disposed in the drive cavity 21, and the output shaft is coaxially connected to the lower end of the drive rod. When the motor 4 is started, the output shaft of the motor 4 drives the drive rod to rotate, and the drive rod drives the centrifugal turntable 3 to rotate, thereby centrifugally extracting the cell sample in the collection section 13 fixed to the centrifugal turntable 3.

[0033] Although the present invention has been described herein with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and implementations may be devised by those skilled in the art that fall within the scope and spirit of the principles disclosed herein. More specifically, within the scope of the present disclosure, the drawings, and the claims, various variations and modifications may be made to the components and / or layout of the subject combination arrangement. In addition to variations and modifications to the components and / or layout, other uses will also be apparent to those skilled in the art.

Claims

1. A collection and extraction device, comprising a centrifugal extraction module (1) and a collection module (2), characterized in that: The centrifugal extraction module (1) is provided with a centrifugal turntable (3) and a motor (4) for driving the centrifugal turntable (3) to rotate, and a fixing hole is provided on the upper side of the centrifugal turntable (3); the collection module (2) is provided with a vacuum pump, and the vacuum pump is connected to a collection needle (6) via an air extraction pipe (5); the collection needle (6) is separated by an elastic diaphragm (7) to form an air extraction chamber (8) and a collection chamber (9); the air extraction pipe (5) is connected to the air extraction chamber (8), and the end of the collection needle (6) is provided with a collection nozzle (10) connected to the collection chamber (9).

2. A collection and extraction device according to claim 1, characterized in that: The collecting needle (6) comprises an air extraction section (11), a diaphragm section (12) and a collecting section (13) which are connected in sequence, and the air extraction section (11), the diaphragm section (12) and the collecting section (13) are all tubular; the upper end of the air extraction section (11) is closed, and the end is connected to the air extraction pipe (5); the lower end of the air extraction section (11) and the upper end of the diaphragm section (12) are detachably connected; the edge of the elastic diaphragm (7) is connected to the inner wall of the diaphragm section (12); the lower end of the diaphragm section (12) and the upper end of the collecting section (13) are detachably connected; the collecting nozzle (10) is placed at the lower end of the collecting section (13).

3. A collection and extraction device according to claim 2, characterized in that: A switch (14) for controlling the start and stop of the vacuum pump is installed on the outer wall of the air extraction section (11).

4. A collection and extraction device according to claim 2, characterized in that: The collection nozzle (10) is detachably connected to a needle (15) or a sealing cover (16).

5. The collection and extraction device according to claim 2, characterized in that: A first thread is provided on the outer wall surrounding the lower end of the exhaust section (11), a second thread is provided on the inner wall surrounding the upper end of the diaphragm section (12), and the first thread is thread-matched and connected to the second thread; a third thread is provided on the outer wall surrounding the lower end of the diaphragm section (12), a fourth thread is provided on the inner wall surrounding the upper end of the collection section (13), and the third thread is thread-matched and connected to the fourth thread.

6. The collection and extraction device according to claim 1, characterized in that: The upper side of the collection module (2) is provided with a placement hole (17) for placing a collection needle (6).

7. The collection and extraction device according to claim 1, characterized in that: A first drawer (18) and a second drawer (19) arranged up and down are provided on the side of the collection module (2).

8. The collection and extraction device according to claim 1, characterized in that: The upper side of the centrifugal extraction module (1) is recessed with a rotation groove (20), and the centrifugal extraction module (1) is correspondingly provided with a drive cavity (21) below the rotation groove (20). The bottom of the rotation groove (20) is provided with a drive hole connected to the drive cavity (21), and a drive rod is rotatably provided in the drive hole. The upper end of the drive rod is connected to the lower side of the centrifugal turntable (3), and the motor (4) is provided in the drive cavity (21), and the output shaft and the lower end of the drive rod are coaxially connected.

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