Constant temperature device for glucose forceps clip test

Abstract

The utility model discloses a constant-temperature device for a glucose forceps clip test, which comprises a box body, a constant-temperature device body and a temperature control device, the box body is provided with a containing cavity, one end of the box body is provided with an opening, and the opening is used for allowing an arm to extend into the containing cavity; the heating assembly is arranged in the box body, and the heating assembly is used for heating air in the box body; the fan is arranged in the box body, and the fan is used for enabling air in the box body to circularly flow; and the temperature control assembly is respectively connected with the heating assembly and the fan, and the temperature control assembly is used for monitoring and controlling the temperature in the box body. The constant temperature device for the glucose clamp test has the advantages that the temperature can be preset, regulated and controlled, and can be monitored in real time, so that the heating temperature is more accurate and can be kept constant.

Description

Technical Field

[0001] The utility model relates to the technical field of glucose clamp test, and further relates to a constant temperature device used for glucose clamp test. Background Art

[0002] The glucose clamp technique, first proposed by Andres et al. in 1966, is a quantitative method for measuring insulin secretion and insulin resistance. It has become the gold standard for assessing and characterizing beta-cell sensitivity to insulin. In recent years, the glucose clamp has also been widely used in studies of insulin pharmacokinetics (PK) and pharmacodynamics (PD).

[0003] During the glucose clamp test, blood samples need to be collected frequently to test blood glucose and insulin. The upper limb of the subject on the blood collection side needs to be kept at a constant temperature of about 50-60℃ using a heating device, which is conducive to fully opening the communicating branches between arteries and veins to obtain arterialized venous blood samples, making blood glucose and insulin testing more accurate.

[0004] Currently, most research centers conducting glucose clamp tests in China use electric heating sleeves to heat the subjects' upper limbs. However, these heating sleeves cannot precisely control the temperature and come into direct contact with the subjects' limbs, which can easily cause skin burns. Some research centers have developed their own thermostats, but these require a blanket to cover the device after heating to maintain a constant temperature. These devices cannot maintain a constant temperature on their own, and there are no preset temperatures or real-time temperature monitoring options.

[0005] Therefore, it is necessary to design a constant temperature device for glucose clamp test to solve the above problems. Utility Model Content

[0006] In response to the above technical problems, the purpose of the present invention is to provide a constant temperature device for glucose clamp test, which has the advantages of preset temperature, adjustable temperature and real-time monitoring, so that the heating temperature is more accurate and can be kept constant.

[0007] In order to achieve the above-mentioned object, the present invention provides a constant temperature device for glucose clamp test, comprising:

[0008] A box body, the box body having a receiving cavity, one end of the box body being provided with an opening, the opening being used for allowing the arm to extend into the receiving cavity;

[0009] A heating component is disposed in the box, and is used to heat the air in the box;

[0010] A fan is provided in the box, and is used to circulate air in the box;

[0011] A temperature control component is connected to the heating component and the fan respectively, and the temperature control component is used to monitor and control the temperature inside the box.

[0012] In some embodiments, a guide plate is provided in the box body, which divides the accommodating cavity into a first accommodating cavity and a second accommodating cavity. The guide plate is provided with a plurality of guide holes arranged at intervals, and the plurality of guide holes connect the first accommodating cavity with the second accommodating cavity.

[0013] In some embodiments, the guide plate is provided with a mounting hole, the fan is mounted on the mounting hole, the mounting hole is located at an end of the guide plate away from the opening, and a plurality of the guide holes are located at an end of the guide plate close to the opening;

[0014] The first accommodating cavity is used to accommodate the arm so that the arm can be placed on the guide plate, and the heating component is arranged in the second accommodating cavity.

[0015] In some embodiments, a support plate is provided in the box body, the support plate is located between the mounting hole and the plurality of the diversion holes, the top of the support plate is connected to the top wall of the box body, the bottom of the support plate is connected to the bottom wall of the box body, and both sides of the support plate are respectively connected to the two side walls of the box body;

[0016] The support plate is connected to the guide plate, and the guide plate divides the support plate into a first support plate and a second support plate. The first support plate is located in the first accommodating cavity, and the second support plate is located in the second accommodating cavity. A first connecting port is provided on the first support plate, and the first connecting port connects the two ends of the first accommodating cavity. A second connecting port is provided on the second support plate, and the first connecting port connects the two ends of the second accommodating cavity. The heating component is provided at the second connecting port.

[0017] In some embodiments, a protective member is provided at the first communication port, and the protective member is a hollow structure.

[0018] In some embodiments, the box body includes a top plate, a bottom plate, two side plates and two end plates, the top plate is parallel to and spaced apart from the bottom plate, the two side plates are parallel to and spaced apart from each other, and the two end plates are parallel to and spaced apart from each other;

[0019] The two sides of the top plate are respectively fixedly connected to the two side plates, the two ends of the top plate are respectively fixedly connected to the two end plates, the two sides of the bottom plate are respectively fixedly connected to the two side plates, the two ends of the bottom plate are respectively fixedly connected to the two end plates, and the opening is provided on one of the end plates.

[0020] In some embodiments, the top plate is an acrylic plate, or the top plate is a composite plate formed by a hard plate and an insulation layer;

[0021] The bottom plate is an acrylic plate, or the bottom plate is a composite plate formed by a hard plate and a thermal insulation layer;

[0022] The side panels are acrylic panels, or are composite panels formed by a hard panel and a thermal insulation layer;

[0023] The end plate is an acrylic plate, or the end plate is a composite plate formed by a hard plate and a thermal insulation layer.

[0024] In some embodiments, the opening is a circular structure or a circular-like structure, and a soft cushion is provided on the bottom side of the opening.

[0025] In some embodiments, the heating component includes a heating plate, and the temperature control component includes a temperature controller and a probe. The temperature controller is arranged on the outside of the box, and the probe is arranged on the inside of the box, and the temperature controller is connected to the probe.

[0026] In some embodiments, the length of the box is 45 cm-55 cm;

[0027] The width of the box is 15cm-25cm;

[0028] The height of the box is 18cm-28cm.

[0029] Compared with the prior art, the thermostat for glucose clamp test provided by the present invention has one of the following beneficial effects:

[0030] In the utility model, the constant temperature device used for the glucose clamp test has the advantages that the temperature can be preset, adjusted, and monitored in real time, so that the heating temperature is more accurate and can be kept constant; by arranging a fan, there is sufficient air circulation space in the box, avoiding direct contact of the heating component with the subject's limbs, and good safety; by setting the box to transparent acrylic material, it is convenient for researchers to observe the skin condition of the subject's upper limbs; by arranging a soft pad at the opening, there will be no discomfort when the arm is extended into the box, which increases the comfort of the subject. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] The preferred embodiments will be described below in a clear and understandable manner with reference to the accompanying drawings to further illustrate the above-mentioned characteristics, technical features, advantages and implementation methods of the present invention.

[0032] Figure 1 This is a schematic structural diagram of a thermostatic device for a glucose clamp test according to a preferred embodiment of the present invention;

[0033] Figure 2 It is a structural diagram of a box body according to a preferred embodiment of the present invention.

[0034] Description of Figure Numbers:

[0035] Box body 1, top plate 11, bottom plate 12, side plate 13, end plate 14, opening 141, guide plate 15, guide hole 151, mounting hole 152, support plate 16, first support plate 161, first connecting port 1611, second support plate 162, second connecting port 1621, heating component 2, fan 3, temperature control component 4, temperature controller 41, probe 42. DETAILED DESCRIPTION

[0036] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the specific implementation methods of the present invention will be described below with reference to the accompanying drawings. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings and other implementation methods can be obtained based on these drawings without inventive work.

[0037] To simplify the drawings, only the parts relevant to the utility model are schematically shown in each figure; they do not represent the actual structure of the product. Furthermore, to simplify the drawings and facilitate understanding, in some figures, only one of the components with the same structure or function is schematically depicted or labeled. In this document, "one" not only means "only one" but also "more than one."

[0038] It should be further understood that the term "and / or" used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0039] It should be noted that, unless otherwise specified or limited, the terms "mounted," "connected," and "connected" should be understood broadly. For example, they can refer to fixed, detachable, or integral connections; mechanical or electrical connections; direct or indirect connections through an intermediary; and internal communication between two components. Those skilled in the art will understand the specific meanings of these terms in this utility model based on the specific circumstances.

[0040] In addition, in the description of the present application, the terms "first", "second", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

[0041] In one embodiment, the reference Figure 1 、 Figure 2The utility model provides a constant temperature device for a glucose clamp test, comprising: a box 1, a heating component 2, a fan 3 and a temperature control component 4. The box 1 has a receiving cavity, and an opening 141 is provided at one end of the box 1. The opening 141 is used for allowing the arm to extend into the receiving cavity; the heating component 2 is arranged in the box 1, and the heating component 2 is used to heat the air in the box 2; the fan 3 is arranged in the box 1, and the fan 3 is used to circulate the air in the box 2; the temperature control component 4 is connected to the heating component 2 and the fan 3 respectively, and the temperature control component 4 is used to monitor and control the temperature in the box 1.

[0042] In this embodiment, the constant temperature device used for the glucose clamp test has the advantages of presettable, adjustable, and real-time temperature monitoring, making the heating temperature more accurate and able to remain constant; by providing a fan 3, there is sufficient air circulation space in the box 1, avoiding direct contact between the heating component 2 and the subject's limbs, thereby improving safety.

[0043] In one embodiment, the reference Figure 1 、 Figure 2 The box body 1 includes a top plate 11, a bottom plate 12, two side plates 13 and two end plates 14. The top plate 11 is arranged parallel to the bottom plate, the two side plates 13 are arranged parallel to each other, and the two end plates 14 are arranged parallel to each other. The two sides of the top plate 11 are fixedly connected to the two side plates 13, the two ends of the top plate 11 are fixedly connected to the two end plates 14, the two sides of the bottom plate 12 are fixedly connected to the two side plates 13, the two ends of the bottom plate 12 are fixedly connected to the two end plates 14, and the opening 141 is provided on one end plate 14. That is, the top plate 11, the bottom plate 12, the two side plates 13 and the two end plates 14 are arranged to form a rectangular parallelepiped structure. Setting the box body 1 as a rectangular parallelepiped structure has the advantages of structural stability and stable placement. Of course, the box body 1 can also be set as a structure of other shapes, such as a trapezoidal structure, a cylindrical structure or a special-shaped structure.

[0044] Specifically, the top panel 11 is an acrylic panel, or a composite panel formed by a hard panel and a thermal insulation layer; the bottom panel 12 is an acrylic panel, or a composite panel formed by a hard panel and a thermal insulation layer; the side panels 13 are acrylic panels, or a composite panel formed by a hard panel and a thermal insulation layer; and the end panels 14 are acrylic panels, or a composite panel formed by a hard panel and a thermal insulation layer. In other words, the box body 1 is a rectangular parallelepiped structure made of acrylic material, or a rectangular parallelepiped structure made of a composite panel formed by a hard panel and a thermal insulation layer.

[0045] In this embodiment, by making the box 1 from acrylic, the entire box 1 is transparent, facilitating observation of the subject's upper limb skin condition and improving experimental safety. By making the box 1 from a composite panel, such as a stainless steel hard panel, the box 1 is formed into a stainless steel box. The interior of the box 1 is coated with a layer of thermal insulation, resulting in a lightweight and durable box. Of course, the box 1 can also be made of other materials, as long as they can provide thermal insulation.

[0046] In one embodiment, the reference Figure 1 、 Figure 2 A deflector 15 is provided within the housing 1, dividing the housing chamber into a first housing chamber and a second housing chamber. The deflector 15 is provided with a plurality of spaced-apart guide holes 151, which connect the first housing chamber with the second housing chamber. Preferably, the guide holes 151 on the deflector 15 are evenly distributed, allowing air circulation between the upper and lower layers, thereby achieving a more uniform temperature within the housing 1.

[0047] A mounting hole 152 is provided on the guide plate 15, and the fan 3 is installed on the mounting hole 152. The mounting hole 152 is located at the end of the guide plate 15 away from the opening 141, and several guide holes 151 are located at the end of the guide plate 15 close to the opening 141; the first accommodating cavity is used to accommodate the arm so that the arm can be placed on the guide plate 15, and the heating component 2 is arranged in the second accommodating cavity.

[0048] Furthermore, a support plate 16 is provided in the box body 1, and the support plate 16 is located between the mounting hole 152 and the several guide holes 151. The top of the support plate 16 is connected to the top wall of the box body 1, the bottom of the support plate 16 is connected to the bottom wall of the box body 1, and the two sides of the support plate 16 are respectively connected to the two side walls of the box body 1; the support plate 16 is connected to the guide plate 15, and the guide plate 15 divides the support plate 16 into a first support plate 161 and a second support plate 162. The first support plate 161 is located in the first accommodating cavity, and the second support plate 162 is located in the second accommodating cavity. A first connecting port 1611 is provided on the first support plate 161, and the first connecting port 1611 connects the two ends of the first accommodating cavity. A second connecting port 1621 is provided on the second support plate 162, and the first connecting port 1611 connects the two ends of the second accommodating cavity. The heating component 2 is arranged at the second connecting port 1621.

[0049] Furthermore, a protective member is provided at the first connecting port 1611, and the protective member is a hollow structure. By providing the protective member at the first connecting port 1611, the subject's hand can be prevented from reaching into the fan 3, thereby improving the safety of the detection; at the same time, the protective member is set as a hollow structure without affecting the air circulation in the box 1.

[0050] Furthermore, the opening 141 is a circular structure or a similar circular structure, and the diameter of the opening 141 is 10cm-16cm, for example, the diameter of the opening 141 is 11cm, 12cm, 13cm, 14cm, 15cm, etc. A soft pad is provided on the bottom side of the opening 141, and the soft pad can be made of a material such as sponge to increase comfort.

[0051] Furthermore, the heating component 2 includes a heating plate. Of course, the heating component 2 can also use a heating rod, etc. The heating component 2 can be an existing heating device, as long as it can heat the box 1. The temperature control component 4 includes a temperature controller 41 and a probe 42. The temperature controller 41 is arranged on the outside of the box 1. For example, the temperature controller 41 can be fixed on the top plate 11, the bottom plate 12, the side plate 13 or the end plate 14. The probe 42 is arranged on the inside of the box 1. The temperature controller 41 is connected to the probe 42 to monitor the temperature inside the box 1 in real time. The heating component 2 and the fan 3 are located at the rear end of the box. The fan 3 can push the heat generated by the heating component 2 to form an air circulation in the box 1, so as to achieve a uniform and constant temperature in the box 1. The heating component 2 and the fan 3 are connected to the temperature controller 41. The power of the heating component 2 and the fan 3 is controlled by the temperature controller 41 to achieve temperature regulation in the box 1.

[0052] Furthermore, the length of the box 1 is 45 cm to 55 cm; for example, the length of the box 1 is 46 cm, 47 cm, 48 cm, 49 cm, 50 cm, 51 cm, 52 cm, 53 cm, 54 cm, etc. The width of the box 1 is 15 cm to 25 cm; for example, the width of the box 1 is 16 cm, 17 cm, 18 cm, 19 cm, 20 cm, 21 cm, 22 cm, 23 cm, 24 cm, etc. The height of the box 1 is 18 cm to 28 cm; for example, the height of the box 1 is 19 cm, 20 cm, 21 cm, 22 cm, 23 cm, 24 cm, 25 cm, 26 cm, 27 cm, etc. Of course, the box 1 can also be set to other sizes, and its specific size can be set according to actual needs.

[0053] For example, the thermostat for glucose clamp test is made of transparent acrylic material as a whole. The specific length of the box 1 is 50 cm, the width is 20 cm, and the height is 23 cm; the weight is about 7500 g, and the diameter of the opening 141 is 13 cm.

[0054] In this embodiment, the constant temperature device used for the glucose clamp test can solve the problem of maintaining a constant temperature of 50-60°C on the upper limb of the subject on the blood collection side during the glucose clamp test. The device is lightweight and portable, has adjustable and controllable temperature, and is safe and comfortable to use.

[0055] Lightweight and portable: Existing incubators on the market are usually used for breeding, biological cultivation or preservation. They are large in size and their structure is not suitable for heating the upper limbs of the human body. This incubator is lightweight, weighing only about 7500g, and is 50cm long, 20cm wide and 23cm high. It can be placed on the side of the bed for easy use and transportation.

[0056] Adjustable and controllable temperature: The thermostats used in other research centers only have a heating function. After heating, a quilt must be placed over the device to achieve a constant temperature. They cannot maintain a constant temperature on their own, and there is no way to preset or monitor the temperature in real time. This thermostat has the advantages of preset, adjustable, and real-time monitoring of the temperature, ensuring accurate and constant heating temperature.

[0057] Safe and comfortable to use: This constant temperature device has sufficient air circulation space to prevent the heater from directly contacting the subject's limbs, which is safe. The entire device is made of transparent acrylic material, which makes it convenient for researchers to observe the skin condition of the subject's upper limbs. The sponge pad is designed at the arm extension port to increase the comfort of the subject.

[0058] In the above embodiments, the description of each embodiment has its own focus. For parts that are not described or recorded in detail in a certain embodiment, reference can be made to the relevant description of other embodiments.

[0059] It should be noted that the above embodiments can be freely combined as needed. The above are only preferred embodiments of the present invention. It should be noted that those skilled in the art can make several improvements and modifications without departing from the principles of the present invention, and such improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A constant temperature device for glucose clamp test, characterized in that: include: A box body, the box body having a receiving cavity, one end of the box body being provided with an opening, the opening being used for allowing the arm to extend into the receiving cavity; A heating component is disposed in the box, and is used to heat the air in the box; A fan is provided in the box, and is used to circulate air in the box; A temperature control component is connected to the heating component and the fan respectively, and the temperature control component is used to monitor and control the temperature inside the box.

2. The constant temperature device for glucose clamp test according to claim 1, characterized in that: A guide plate is provided in the box body, and the guide plate divides the accommodating chamber into a first accommodating chamber and a second accommodating chamber. The guide plate is provided with a plurality of guide holes arranged at intervals, and the plurality of guide holes connect the first accommodating chamber with the second accommodating chamber.

3. The constant temperature device for glucose clamp test according to claim 2, characterized in that: The guide plate is provided with a mounting hole, and the fan is mounted on the mounting hole. The mounting hole is located at an end of the guide plate away from the opening, and a plurality of the guide holes are located at an end of the guide plate close to the opening. The first accommodating cavity is used to accommodate the arm so that the arm can be placed on the guide plate, and the heating component is arranged in the second accommodating cavity.

4. The constant temperature device for glucose clamp test according to claim 3, characterized in that: A support plate is provided in the box body, the support plate is located between the mounting hole and the plurality of guide holes, the top of the support plate is connected to the top wall of the box body, the bottom of the support plate is connected to the bottom wall of the box body, and both sides of the support plate are respectively connected to the two side walls of the box body; The support plate is connected to the guide plate, and the guide plate divides the support plate into a first support plate and a second support plate. The first support plate is located in the first accommodating cavity, and the second support plate is located in the second accommodating cavity. A first connecting port is provided on the first support plate, and the first connecting port connects the two ends of the first accommodating cavity. A second connecting port is provided on the second support plate, and the first connecting port connects the two ends of the second accommodating cavity. The heating component is provided at the second connecting port.

5. The constant temperature device for glucose clamp test according to claim 4, characterized in that: A protective member is provided at the first communication port, and the protective member is a hollow structure.

6. The constant temperature device for glucose clamp test according to any one of claims 1 to 5, characterized in that: The box body includes a top plate, a bottom plate, two side plates and two end plates, the top plate and the bottom plate are arranged parallel and spaced apart, the two side plates are arranged parallel and spaced apart, and the two end plates are arranged parallel and spaced apart; The two sides of the top plate are respectively fixedly connected to the two side plates, the two ends of the top plate are respectively fixedly connected to the two end plates, the two sides of the bottom plate are respectively fixedly connected to the two side plates, the two ends of the bottom plate are respectively fixedly connected to the two end plates, and the opening is provided on one of the end plates.

7. The constant temperature device for glucose clamp test according to claim 6, characterized in that: The top plate is an acrylic plate, or the top plate is a composite plate formed by a hard plate and a thermal insulation layer; The bottom plate is an acrylic plate, or the bottom plate is a composite plate formed by a hard plate and a thermal insulation layer; The side panels are acrylic panels, or are composite panels formed by a hard panel and a thermal insulation layer; The end plate is an acrylic plate, or the end plate is a composite plate formed by a hard plate and a thermal insulation layer.

8. The constant temperature device for glucose clamp test according to claim 6, characterized in that: The opening is a circular structure or a similar circular structure, and a soft cushion is provided on the bottom side of the opening.

9. The constant temperature device for glucose clamp test according to claim 6, characterized in that: The heating component includes a heating plate, and the temperature control component includes a temperature controller and a probe. The temperature controller is arranged on the outside of the box, and the probe is arranged on the inside of the box. The temperature controller is connected to the probe.

10. The constant temperature device for glucose clamp test according to claim 6, characterized in that: The length of the box is 45cm-55cm; The width of the box is 15cm-25cm; The height of the box is 18cm-28cm.

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