Cell preparation preparation device
By introducing cold plates, extrusion modules and refrigeration modules into the cell preparation device, the problem of uncontrollable temperature is solved, precise temperature control is achieved, and the effectiveness and stability of cell preparations are ensured.
Patent Information
- Application Number
- CN202421144221.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-23
- Publication Date
- 2025-10-03
- Estimated Expiration
- 2034-05-23
AI Technical Summary
Existing cell preparation mixing devices operating at room temperature cannot meet the temperature requirements of special cell fluids, resulting in uncontrollable temperature and affecting the efficacy of the preparation.
A cell preparation preparation device consisting of a cold plate, an extrusion module and a refrigeration module was designed. Through the combination of air ducts and heat dissipation modules, precise control of the temperature inside the preparation box was achieved to ensure that the temperature was within the specified range.
The temperature of cell preparations can be controlled, ensuring the effectiveness and stability of the preparations and avoiding failure problems caused by uncontrollable temperature.
Smart Images

Figure CN223404859U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of medical equipment, and in particular to a cell preparation device. Background Art
[0002] Currently, in the field of medical devices, especially in cell preparations, extrusion mixing is generally used for mixing. Existing mixing devices are generally operated at room temperature. However, for some special cell fluid preparations, mixing must be carried out within a specified temperature range, otherwise the preparation will become ineffective. Moreover, the above temperature requirements are generally low, and room temperature cannot meet the above requirements, resulting in uncontrollable temperature during the cell fluid mixing process. Utility Model Content
[0003] The main purpose of this application is to provide a cell preparation preparation device, aiming to solve the defect of uncontrollable temperature in the prior art.
[0004] This application achieves the above objectives through the following technical solutions:
[0005] A cell preparation device comprises a preparation box;
[0006] a cold plate, the cold plate being disposed in the preparation box;
[0007] An extrusion module, the extrusion module is arranged on the preparation box, and the extrusion module is used to extrude the mixed bag placed in the preparation box;
[0008] An air duct is provided on the preparation box, a refrigeration module connected to the cold plate is further provided in the air duct, and a heat dissipation module is provided at the outlet end of the air duct.
[0009] Optionally, the extrusion module includes a mounting plate, a push plate and an extrusion plate, and the mounting plate is connected to the preparation box; a number of guide rods are slidably arranged on the mounting plate, one end of each guide rod is respectively connected to the push plate, and the other end thereof is respectively connected to the extrusion plate; a driving module for driving the push plate to reciprocate is also provided on the mounting plate.
[0010] Optionally, a linear motion bearing is further provided between each guide rod and the mounting plate.
[0011] Optionally, at least four guide rods are slidably provided on the mounting plate, one end of each guide rod is connected to the push plate, and the other end thereof is connected to the extrusion plate.
[0012] Optionally, along the length direction of the extrusion plate, one side of the extrusion plate is hingedly connected to each of the guide rods on the same side through a hinge seat; the other side of the extrusion plate is connected to each of the guide rods on the same side through a door buckle and a lock buckle seat that cooperate with each other.
[0013] Optionally, the drive module includes a drive motor and a support plate, the support plate is connected to the mounting plate, and the drive motor is arranged on the support plate; the drive module also includes a ball screw, the two ends of the ball screw are respectively rotatably connected to the mounting plate and the support plate; the ball screw is connected to the drive motor power, and the push plate is connected to the ball screw.
[0014] Optionally, two photoelectric sensors are provided on the support plate, and the two photoelectric sensors are provided at two end points of the push plate stroke.
[0015] Optionally, the refrigeration module includes a semiconductor refrigeration plate, a hot end of the semiconductor refrigeration plate is connected to a radiator, and a cold end of the semiconductor refrigeration plate is connected to the cold plate via a heat conducting plate.
[0016] Optionally, the refrigeration module further includes a bakelite board and sealing cotton, the semiconductor refrigeration sheet is embedded in the bakelite board; the heat conducting plate is connected to the bakelite board, and sealing cotton is further provided between the heat conducting plate and the bakelite board.
[0017] Optionally, the heat sink includes a base, one side of which is connected to the bakelite board and affixed to the hot end of the semiconductor refrigeration plate; the other side of the base is integrally connected to a plurality of heat dissipation fins.
[0018] Compared with the prior art, this application has the following beneficial effects:
[0019] The present application includes a preparation box, wherein a cold plate is provided in the preparation box, and an extrusion module for extruding a mixed bag is also provided in the preparation box; an air duct is provided on the preparation box, and a refrigeration module is further provided in the air duct, the refrigeration module is connected to the cold plate, and a heat dissipation module is further provided at the outlet end of the air duct;
[0020] When in use, the mixed bag is hung in the preparation box, and the temperature of the cold plate is lowered by the refrigeration module. The cold plate ensures that the temperature in the preparation box meets the requirements, thereby improving the temperature control capability;
[0021] At the same time, the refrigeration module and the heat dissipation module are placed outside the preparation box through the air duct to ensure the relative closure of the preparation box, avoid excessive interference from the outside world, and improve the temperature stability in the preparation box. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 This is a schematic structural diagram of a cell preparation preparation device provided in embodiment 1 of the present application;
[0023] Figure 2 A cross-sectional view of a cell preparation preparation device provided in embodiment 1 of the present application;
[0024] Figure 3 A top view of the extrusion die;
[0025] Figure 4 It is a bottom view of the extrusion die;
[0026] Figure 5 It is a structural diagram of the refrigeration module;
[0027] Figure 6 This is the exploded view of the refrigeration module;
[0028] Figure markings: 1-preparation box, 2-cold plate, 3-air duct, 4-mounting plate, 5-push plate, 6-extrusion plate, 7-guide rod, 8-linear motion bearing, 9-hinge seat, 10-door buckle, 11-lock seat, 12-drive motor, 13-support plate, 14-ball screw, 15-photoelectric sensor, 16-semiconductor refrigeration plate, 17-radiator, 18-bakelite board, 19-sealing cotton, 20-cooling fan, 1701-base, 1702-heat sink fin.
[0029] The purpose, features and advantages of this application will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0031] It should be noted that all directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.
[0032] In this utility model, unless otherwise specified or limited, the terms "connection" and "fixation" should be understood in a broad sense. For example, "fixation" can mean fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two elements or interaction between two elements, unless otherwise specified. For those skilled in the art, the specific meanings of the above terms in this utility model can be understood according to specific circumstances.
[0033] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "and / or" appearing throughout the text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
[0034] Implementation Method 1
[0035] Reference Figures 1 to 6 This embodiment is an optional embodiment of the present application, which discloses a cell preparation preparation device, including a preparation box 1, a cold plate 2 is arranged in the preparation box 1, and an extrusion module is also arranged on the preparation box 1, the extrusion module includes a mounting plate 4, a push plate 5 and an extrusion plate 6, wherein the mounting plate 4 is connected to the preparation box 1 through a screw, and a plurality of guide rods 7 are further arranged on the mounting plate 4, wherein the guide rods 7 are preferably 4, and the guide rods 7 are respectively arranged at the four corners of the mounting plate 4, and each of the guide rods 7 is slidably connected to the mounting plate 4 through a linear motion bearing 8;
[0036] The extrusion plate 6 is arranged in the preparation box 1 and is located on the upper side of the cold plate 2. The mixing bag is placed between the cold plate 2 and the extrusion plate 6. Along the length direction of the extrusion plate 6, the guide rods 7 located on the left side of the extrusion plate 6 are connected to the same hinge seat 9. The hinge seat 9 is hingedly connected to the left side of the extrusion plate 6 through a pin, and the guide rods 7 located on the right side of the extrusion plate 6 are connected to the same lock seat 11. A door buckle 10 adapted to the lock seat 11 is provided on the right side of the extrusion plate 6.
[0037] It should be noted that, in the above technical solution, the positions of the hinge seat 9 and the lock seat 11 can be swapped;
[0038] In the above structure, when the door buckle 10 and the lock seat 11 are separated from each other, the extrusion plate 6 and the guide rod 7 are in a completely unlocked state. Therefore, the extrusion plate 6 can be fully opened through the hinge seat 9, avoiding the extrusion plate 6 from causing obstacles to the placement of the mixed liquid bag, thereby improving the convenience of using the device;
[0039] At the same time, the four guide rods 7 can also effectively improve the stability of the push plate 5 and the extrusion plate 6;
[0040] A drive module is also provided on the mounting plate 4, and the drive module includes a drive motor 12, a support plate 13 and a ball screw 14, wherein the support plate 13 is a U-shaped structure, and its open end is connected to the mounting plate 4, and the drive motor 12 is provided on the support plate 13; the ball screw 14 is arranged along a sliding direction parallel to the guide rod 7, and the two ends of the ball screw 14 are respectively connected to the mounting plate 4 and the support plate 13 for rotation; the ball screw 14 is connected to the drive motor 12 through a synchronous belt and a synchronous wheel, and the push plate 5 is connected to the ball screw 14;
[0041] Two photoelectric sensors 15 are also provided on the support plate 13. The two photoelectric sensors 15 are provided at the two end points of the travel of the push plate 5.
[0042] The above structure can realize the reciprocating motion of the extrusion module, and the operation is stable and the structure is simple; at the same time, the position of the push plate 5 can be monitored by the two photoelectric sensors 15 to avoid adverse working conditions such as excessive extrusion.
[0043] The preparation box 1 is further provided with an air duct 3, one end of the air duct 3 is an inlet end, and the other end is an outlet end, wherein a refrigeration module is provided in the inlet end of the air duct 3, and the refrigeration module includes a semiconductor refrigeration sheet 16, a bakelite board 18 and a sealing cotton 19. A plurality of mounting grooves are provided on the bakelite board 18, and each of the semiconductor refrigeration sheets 16 is respectively embedded in each of the mounting grooves. The sealing cotton 19 has an annular structure, which encloses each of the semiconductor refrigeration sheets 16. At the same time, the sealing cotton 19 is provided on the side of the bakelite board 18 that is in contact with the preparation box 1;
[0044] The cold end of the semiconductor refrigeration sheet 16 is connected to the cold plate 2. In order to improve the cooling effect and accelerate the heat flow, a heat conducting plate is further provided between the cold end of the semiconductor refrigeration sheet 16 and the cold plate 2.
[0045] The cold end of the semiconductor refrigeration plate 16 can be sealed by the sealing cotton 19 to reduce heat loss;
[0046] A heat sink 17 is provided at the hot end of the semiconductor. The heat sink 17 includes a base 1701. One side of the base 1701 is connected to the bakelite 18 and is in contact with the hot end of the semiconductor refrigeration plate 16. The other side of the base 1701 is integrally connected to a plurality of heat dissipation fins 1702.
[0047] A heat dissipation module is further provided at the outlet end of the air duct 3 , and the heat dissipation module includes a heat dissipation fan 20 .
[0048] When in use, the mixed bag is hung in the preparation box, and the temperature of the cold plate is lowered by the refrigeration module. The cold plate ensures that the temperature in the preparation box meets the requirements, thereby improving the temperature control capability;
[0049] At the same time, the refrigeration module and the heat dissipation module are placed outside the preparation box through the air duct to ensure the relative closure of the preparation box, avoid excessive interference from the outside world, and improve the temperature stability in the preparation box.
[0050] The above are only preferred embodiments of the present application and do not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present application.
Claims
1. A cell preparation device, characterized in that: It includes a preparation box (1); a cold plate (2), the cold plate (2) being arranged in the preparation box (1); An extrusion module, the extrusion module being arranged on the preparation box (1), and the extrusion module being used for extruding the mixed bag placed in the preparation box (1); An air duct (3) is provided on the preparation box (1), a refrigeration module connected to the cold plate (2) is further provided in the air duct (3), and a heat dissipation module is provided at the outlet end of the air duct (3).
2. A cell preparation preparation device according to claim 1, characterized in that: The extrusion module comprises a mounting plate (4), a push plate (5) and an extrusion plate (6); the mounting plate (4) is connected to the preparation box (1); a plurality of guide rods (7) are slidably provided on the mounting plate (4), one end of each guide rod (7) is respectively connected to the push plate (5), and the other end thereof is respectively connected to the extrusion plate (6); the mounting plate (4) is also provided with a driving module for driving the push plate (5) to reciprocate.
3. A cell preparation preparation device according to claim 2, characterized in that: A linear motion bearing (8) is also provided between each of the guide rods (7) and the mounting plate (4).
4. A cell preparation preparation device according to claim 2, characterized in that: At least four guide rods (7) are slidably arranged on the mounting plate (4).
5. A cell preparation preparation device according to claim 2, characterized in that: Along the length direction of the extrusion plate (6), one side of the extrusion plate (6) is hingedly connected to each of the guide rods (7) on the same side through a hinge seat (9); the other side of the extrusion plate (6) is connected to each of the guide rods (7) on the same side through a door catch (10) and a lock catch seat (11) that cooperate with each other.
6. A cell preparation preparation device according to claim 2, characterized in that: The driving module comprises a driving motor (12) and a support plate (13), wherein the support plate (13) is connected to the mounting plate (4), and the driving motor (12) is arranged on the support plate (13); the driving module also comprises a ball screw (14), wherein both ends of the ball screw (14) are respectively connected to the mounting plate (4) and the support plate (13) for rotation; the ball screw (14) is connected to the driving motor (12) in terms of power, and the push plate (5) is connected to the ball screw (14).
7. A cell preparation preparation device according to claim 6, characterized in that: Two photoelectric sensors (15) are provided on the support plate (13), and the two photoelectric sensors (15) are arranged at two end points of the travel of the push plate (5).
8. The cell preparation preparation device according to claim 1, characterized in that: The refrigeration module comprises a semiconductor refrigeration plate (16), the hot end of the semiconductor refrigeration plate (16) is connected to a radiator (17), and the cold end of the semiconductor refrigeration plate (16) is connected to the cold plate (2) via a heat conduction plate.
9. A cell preparation preparation device according to claim 8, characterized in that: The refrigeration module further comprises an electric board (18) and sealing cotton (19), wherein the semiconductor refrigeration sheet (16) is embedded in the electric board (18); the heat conducting plate is connected to the electric board (18), and sealing cotton (19) is further provided between the heat conducting plate and the electric board (18).
10. The cell preparation preparation device according to claim 9, characterized in that: The heat sink (17) includes a base (1701), one side of which is connected to the bakelite board (18) and affixed to the hot end of the semiconductor refrigeration plate (16); and the other side of the base (1701) is integrally connected with a plurality of heat dissipation fins (1702).