Gas flow control device of bioreactor

By designing an L-shaped outlet pipe and a turntable valve body structure in the bioreactor, combined with an internal threaded cylinder and a knob, convenient control of gas flow and foreign matter filtration are achieved, solving the problem of inconvenient flow control in the existing technology and improving the regulation efficiency and emission stability.

CN223422682UActive Publication Date: 2025-10-10BEIJING HUAFANG TIANSHI BIOPHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202422750937.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-10-10
Estimated Expiration
2034-11-12

AI Technical Summary

Technical Problem

Gas flow control in existing bioreactors is inconvenient, especially in large-scale reaction vessels, where it is difficult to adjust the flow controller conveniently.

Method used

A gas flow control device was designed. By installing an L-shaped outlet pipe and a control box on the top of the reactor vessel, a turntable valve body and a gear rack structure were used in combination with an internal threaded cylinder and a knob to achieve bottom adjustment of the gas flow rate. A filter was also equipped to filter out foreign matter.

Benefits of technology

It improves the convenience of adjusting the gas flow, ensures the stability of gas emissions, and can effectively filter foreign matter, making subsequent processing easier.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a gas flow control device of a bioreactor, which belongs to the field of bioreactors, and comprises an end cover arranged at the top of a reactor container, a gas outlet pipe is fixed on one side above the end cover, the gas outlet pipe is of an L-shaped structure, the gas outlet pipe is communicated with the inside of the reactor container, and the end cover is fixed on the end cover. A vertical plate is arranged on one side of the reactor container and extends upwards, a control box is fixed to the top of the vertical plate, the control box and the air outlet pipe are equal in height, a connecting pipe is connected between the control box and the air outlet pipe, a butt joint is fixed to the end, away from the connecting pipe, of the control box, and a rotary disc valve body is rotationally installed in the control box. The rotary disc valve body is arranged between the butt joint and the connecting pipe, a through groove is transversely formed in the surface of the rotary disc valve body, the gas emission flow is controlled by adjusting the angle of the valve body, the valve body can be adjusted by rotating an inner threaded cylinder at the bottom, the purpose of adjusting the high-position air valve at the bottom is achieved, and the convenience during adjustment is improved.
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Description

Technical Field

[0001] The utility model relates to the field of bioreactors, and more particularly to a gas flow control device for a bioreactor. Background Art

[0002] A bioreactor is a device system that utilizes the biological functions of enzymes or organisms (such as microorganisms, plant cells, animal cells, etc.) to obtain target products through biochemical reactions or the metabolism of the organism itself in vitro or in vivo. A bioreactor is a closed container with a stirring function that can meet the functions of stirring, temperature control, feeding, and exhausting the internal substances.

[0003] During the biological reaction process, a certain amount of gas is generated. This gas needs to be discharged from the container. However, due to the excessive pressure inside the container, the gas flow rate is relatively fast when it is discharged. Therefore, in order to effectively control the exhaust gas flow rate in existing equipment, a flow controller is installed in the exhaust pipe. However, the reaction container is often large in size and the gas is placed at the top, which makes it extremely inconvenient to adjust the flow controller. Utility Model Content

[0004] 1. Technical problems to be solved

[0005] In view of the problems existing in the prior art, the purpose of the present invention is to provide a gas flow control device for a bioreactor, which can control the flow at the bottom and improve the convenience of adjustment.

[0006] 2. Technical solution

[0007] In order to solve the above problems, the present invention adopts the following technical solutions.

[0008] A gas flow control device for a bioreactor comprises an end cover installed on the top of the reactor container, an air outlet pipe is fixed on one side above the end cover, the air outlet pipe is in an L-shaped structure, the air outlet pipe passes through the interior of the reactor container, a vertical plate is provided on one side of the reactor container, the vertical plate extends upward, a control box is fixed on the top of the vertical plate, the control box is at the same height as the air outlet pipe, a connecting pipe is connected between the control box and the air outlet pipe, a docking joint is fixed on one end of the control box facing away from the connecting pipe, a turntable valve body is rotatably installed inside the control box, the turntable valve body is placed between the docking joint and the connecting pipe, a through groove is horizontally opened on the surface of the turntable valve body, the two ends of the through groove correspond to the docking joint and the connecting pipe respectively, a gear is concentrically fixed to one side of the turntable valve body, the gear is placed on the outside of the control box, a gear rod is vertically slidably installed on one side of the control box, and the gear rod is meshed with the gear.

[0009] Furthermore, a plurality of support plates are evenly arranged on one side of the vertical plate, a sliding rod is arranged at the bottom of the gear rod, and the sliding rod passes through the plurality of support plates.

[0010] Furthermore, an internal threaded barrel is rotatably installed between the two support plates at the bottom, a knob is provided at the bottom of the internal threaded barrel, and the bottom end of the slide rod is screwed into the interior of the lower internal threaded barrel.

[0011] Furthermore, a convex strip is provided on one side of the surface of the sliding rod, and the convex strip passes through one of the support plates.

[0012] Furthermore, a filter screen is installed at one end of the through groove away from the connecting pipe, and grooves are symmetrically provided on both sides of one end of the through groove.

[0013] Furthermore, extension plates are provided on both sides of the filter screen, and the extension plates are placed inside the groove. The extension plates are screwed and fixed by locking bolts, and the locking bolts are placed inside the groove.

[0014] 3. Beneficial effects

[0015] Compared with the existing technology, the advantages of the present invention are: the present invention provides a gas flow control device for a bioreactor, which controls the flow of gas emissions by adjusting the angle of the valve body, and the adjustment of the valve body can be achieved by rotating the internal threaded cylinder at the bottom, thereby achieving the purpose of adjusting the high air valve at the bottom and improving the convenience during adjustment.

[0016] When the gas flows through the valve body, it passes through the filter to filter out foreign matter in the gas to prevent foreign matter from flowing out. At the same time, the filtered foreign matter will remain inside the valve body for subsequent centralized processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the installation three-dimensional structure of the utility model;

[0018] Figure 2 For the utility model Figure 1 Schematic diagram of the enlarged structure of area A;

[0019] Figure 3 This is a schematic diagram of the three-dimensional structure of the rotary disc valve body of the present utility model.

[0020] Explanation of the numbers in the figure: 1. Reactor container; 2. End cover; 7. Air outlet pipe; 8. Vertical plate; 9. Control box; 10. Connector; 11. Connecting pipe; 12. Turntable valve body; 13. Gear; 14. Through groove; 15. Recess; 16. Filter screen; 17. Extension plate; 18. Locking bolt; 19. Support plate; 20. Slide rod; 21. Gear rod; 22. Raised strip; 23. Internally threaded barrel; 24. Knob. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention; it is obvious that the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0022] Example:

[0023] See also Figure 1 and Figure 2 As shown, a gas flow control device for a bioreactor comprises an end cover 2 mounted on the top of a reactor container 1, an air outlet pipe 7 is fixed to one side above the end cover 2, the air outlet pipe 7 is in an L-shaped structure so that the air is discharged in a horizontal direction, the air outlet pipe 7 is communicated with the interior of the reactor container 1, and the gas generated by the reaction of the internal substances can only be discharged through the air outlet pipe 7, a vertical plate 8 is provided on one side of the reactor container 1, the vertical plate 8 extends upward, a control box 9 is fixed on the top of the vertical plate 8, the control box 9 is circular, the control box 9 is at the same height as the air outlet pipe 7, a connecting pipe 11 is connected between the control box 9 and the air outlet pipe 7, a docking joint 10 is fixed to the end of the control box 9 facing away from the connecting pipe 11, and a rotary valve is rotatably installed inside the control box 9 Body 12, the turntable valve body 12 is placed between the docking joint 10 and the connecting pipe 11, and a through groove 14 is horizontally opened on the surface of the turntable valve body 12. The two ends of the through groove 14 correspond to the docking joint 10 and the connecting pipe 11 respectively. When the through groove 14 is in a horizontal state, its internal flow is the largest. At this time, the flow rate of the gas flowing through can be controlled by controlling the overlapping area of ​​the through groove 14 and the flow channels at both ends inside the control box 9. A gear 13 is concentrically fixed on one side of the turntable valve body 12, and the gear 13 is placed on the outside of the control box 9. A gear rod 21 is vertically slidably installed on one side of the control box 9. The gear rod 21 is engaged with the gear 13. By moving the gear rod 21 to drive the gear 13 to rotate, the turntable valve body 12 is driven to rotate.

[0024] Among them, multiple support plates 19 are evenly arranged on one side of the vertical plate 8, and a sliding rod 20 is arranged at the bottom of the gear rod 21. The sliding rod 20 passes through multiple support plates 19. The support plates 19 can ensure that the sliding rod 20 can only move in the vertical direction, and then drive the gear rod 21 to move only in the vertical direction.

[0025] Please refer to Figure 1 As shown, an internal threaded barrel 23 is rotatably installed between the two support plates 19 at the bottom, and a knob 24 is provided at the bottom of the internal threaded barrel 23. The internal threaded barrel 23 can be easily controlled by rotating the bottom knob 24. The bottom end of the slide rod 20 is screwed into the interior of the lower internal threaded barrel 23. At this time, the height of the slide rod 20 can be controlled by screwing the internal threaded barrel 23, and then the height of the gear rod 21 can be controlled.

[0026] Please refer to Figure 1 and Figure 2 As shown, a ridge 22 is provided on one side of the surface of the slide bar 20 , and the ridge 22 passes through one of the support plates 19 . The ridge 22 can prevent the slide bar 20 from rotating, so that the slide bar 20 can only move vertically.

[0027] Please refer to Figure 3 As shown, a filter screen 16 is installed at one end of the through groove 14 away from the connecting pipe 11, and grooves 15 are symmetrically opened on both sides of one end of the through groove 14. Extension plates 17 are provided on both sides of the filter screen 16, and the extension plates 17 are placed inside the groove 15. The extension plates 17 are screwed and fixed by locking bolts 18, and the locking bolts 18 are placed inside the groove 15 to ensure that the surface of the rotary valve body 12 is flat to prevent obstruction caused by protrusions during rotation.

[0028] When closing the valve, the gear rod 21 needs to be controlled to move downward so that the rotary valve body 12 rotates counterclockwise. At this time, the end of the through groove 14 close to the connecting pipe 11 is tilted upward to prevent the internal filtered foreign matter from flowing back and blocking the connecting pipe 11. The foreign matter inside is always placed inside the through groove 14, so that the internal foreign matter can be cleaned when the rotary valve body 12 is removed.

[0029] Working principle: When in use, first keep the reactor container 1 in a vertical state and keep the reactor container 1 sealed by the end cover 2 so that the internal gas can only be discharged through the outlet pipe 7. Since the bottom of the slide rod 20 is screwed into the inner threaded tube 23, and the ridge 22 can prevent the slide rod 20 from rotating, when the inner threaded tube 23 is rotated by the knob 24, the slide rod 20 can be controlled to adjust its height, and then the height of the gear rod 21 is controlled. The cooperation between the gear rod 21 and the gear 13 drives the turntable valve body 12 to rotate to adjust the angle of the through groove 14. When the through groove 14 is in a horizontal state, the gas flowing out of the outlet pipe 7 flows through the through groove 14 to the docking head 10 and is discharged through the pipeline. At this time, the angle of the turntable valve body 12 is controlled to control the overlapping area of ​​the through groove 14 and the internal channel of the control box 9 to control the flow of the gas. When the gas flows through the turntable valve body 12, the gas will pass through the filter 16, and the foreign matter in the gas will be filtered out by the filter 16 and retained in the turntable valve body 12 for centralized treatment.

[0030] The above description is merely a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto. Any person skilled in the art who, within the technical scope disclosed in the present invention, makes equivalent substitutions or modifications based on the technical solutions and improved concepts of the present invention shall be covered by the scope of protection of the present invention.

Claims

1. A gas flow control device for a bioreactor, comprising an end cap (2) mounted on the top of a reactor container (1), wherein an air outlet pipe (7) is fixed to one side above the end cap (2), and characterized in that: The outlet pipe (7) is in an L-shaped structure. The outlet pipe (7) is connected to the interior of the reactor container (1). A vertical plate (8) is provided on one side of the reactor container (1). The vertical plate (8) extends upward. A control box (9) is fixed on the top of the vertical plate (8). The control box (9) is at the same height as the outlet pipe (7). A connecting pipe (11) is connected between the control box (9) and the outlet pipe (7). A docking joint (10) is fixed to the end of the control box (9) facing away from the connecting pipe (11). A rotating joint (11) is installed inside the control box (9). A rotary valve body (12) is provided between the butt joint (10) and the connecting pipe (11). A through groove (14) is transversely provided on the surface of the rotary valve body (12). The two ends of the through groove (14) correspond to the butt joint (10) and the connecting pipe (11) respectively. A gear (13) is concentrically fixed to one side of the rotary valve body (12). The gear (13) is provided outside the control box (9). A gear rod (21) is vertically slidably installed on one side of the control box (9). The gear rod (21) is meshed with the gear (13).

2. The gas flow control device for a bioreactor according to claim 1, characterized in that: A plurality of support plates (19) are evenly arranged on one side of the vertical plate (8), a sliding rod (20) is arranged at the bottom of the gear rod (21), and the sliding rod (20) passes through the plurality of support plates (19).

3. The gas flow control device for a bioreactor according to claim 2, characterized in that: An internal threaded barrel (23) is rotatably mounted between the two lower support plates (19), a knob (24) is provided at the bottom of the internal threaded barrel (23), and the bottom end of the slide rod (20) is screwed into the interior of the lower internal threaded barrel (23).

4. The gas flow control device for a bioreactor according to claim 3, characterized in that: A convex strip (22) is provided on one side of the surface of the slide rod (20), and the convex strip (22) passes through one of the support plates (19).

5. The gas flow control device for a bioreactor according to claim 1, characterized in that: A filter screen (16) is installed at one end of the through groove (14) away from the connecting pipe (11), and grooves (15) are symmetrically formed on both sides of one end of the through groove (14).

6. The gas flow control device for a bioreactor according to claim 5, characterized in that: Extension plates (17) are provided on both sides of the filter screen (16), and the extension plates (17) are placed inside the groove (15). The extension plates (17) are screwed and fixed by locking bolts (18), and the locking bolts (18) are placed inside the groove (15).