Titration device for drug analysis

Abstract

The utility model discloses a medicine analysis titration device, which relates to the technical field of analysis titration devices and comprises a base and a support rod in flange connection with one end of the top of the base, the outer arc wall of the support rod is sleeved with a support plate, the top of one end of the support plate is fixedly connected with a balancing weight, and one end, far away from the balancing weight, of the support plate is provided with an arc-shaped notch; according to the utility model, a plurality of burettes are placed in the channel I of the turntable, and an analysis bottle is placed at the center of the fixed seat, so that the burettes are prevented from being placed in a laboratory in a scattered manner, a working area is kept tidy and ordered, and the turntable is rotated during each titration, so that the burettes can be aligned to the bottleneck of the analysis bottle, and the titration accuracy is improved. At the moment, an operator only needs to control the burette without respectively controlling two different devices by two hands, so that the titration process is more convenient, and meanwhile, the eccentric motor at the bottom of the fixed seat can assist in slightly shaking the analysis bottle, so that an internal solution is more fully reacted, and the accuracy of an experiment is ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of analytical titration devices, in particular to a drug analytical titration device. Background Art

[0002] Pharmaceutical analysis titration is a method used in the pharmaceutical testing process to measure the content of a certain component in the drug through titration. The titration method specifically involves slowly and evenly adding a standard solution of known concentration to the sample solution, allowing the standard solution to chemically react with the component to be measured in the sample solution. The volume of the standard solution consumed is then visually observed and the analysis results are calculated.

[0003] Existing drug testing and analysis titration devices usually place an analysis bottle. Multiple drugs are titrated into the analysis bottle in sequence for reaction. During this period, the operator needs to shake the analysis bottle to allow the multiple solutions to fully react to ensure the accuracy of the final result. During this period, the experimenter needs to change the titration tube multiple times and drip the drug solution into the analysis bottle. In addition, the operator needs to operate the titration tube while holding the analysis bottle, which is relatively inconvenient.

[0004] In view of this, this application is hereby filed. Utility Model Content

[0005] The purpose of the present invention is to provide a drug analysis titration device to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the utility model provides a drug analysis titration device, including a base and a support rod with a flange connected to one end of the top of the base, a support plate is sleeved on the outer arc wall of the support rod, a counterweight block is fixedly connected to the top of one end of the support plate, an arc-shaped recess is provided at the end of the support plate away from the counterweight block, a turntable is rotatably connected in the recess at the end of the support plate away from the counterweight block, a plurality of channels 1 distributed in a circular array and passing through axially are provided on the top of the turntable, a clamping mechanism is provided in channel 1, a burette is provided in channel 1, a groove 1 is provided at the top of the base directly below one of the channels 1 away from the counterweight block, a fixing seat is provided in groove 1, and the fixing seat is coaxially arranged with one of the channels away from the counterweight block.

[0007] Furthermore, a circumferentially penetrating slide groove 1 is provided at the top and bottom ends of the inner arc wall of the recess on the support plate, and the longitudinal section of the slide groove 1 is in the shape of "丄". The top and bottom ends of the outer arc wall of the turntable are fixedly connected with a limiting ring, the limiting ring is adapted to the slide groove 1 and the limiting ring is slidably connected in the slide groove 1, and a plurality of grooves 2 distributed in a circular array are radially provided on the outer arc wall of the turntable, and a groove 3 is provided on the inner arc wall of the recess on the support plate at a position corresponding to the groove 2.

[0008] Furthermore, a limiting bead is embedded in the groove 2 on the outer arc wall of the turntable, and a reset spring 1 is fixedly connected to the side wall of the limiting bead close to the axis of the turntable. The elastic direction of the reset spring 1 is consistent with the radial direction of the turntable, and the end of the reset spring 1 away from the limiting bead is fixedly connected to the inner wall of the groove 2. The cross-sectional radius of the end of the inner arc wall of the groove 2 away from the axis of the turntable is smaller than the end of the inner arc wall of the groove 2 close to the axis of the turntable.

[0009] Furthermore, the clamping mechanism in channel 1 on the turntable includes a rotating rod rotatably connected to the top ends of both sides of the inner arc wall of channel 1, the two rotating rods are symmetrically arranged about the axis of channel 1, and the middle part of the rotating rod and the end of the rotating rod away from the inner arc wall of channel 1 are both rotatably connected to rollers.

[0010] Furthermore, a return spring 2 is fixedly connected to a side wall of the inner arc wall of the channel 1 at one end of the rotating rod away from the rotating connection between the rotating rod and the channel 1, and a slider is fixedly connected to the end of the return spring 2 away from the rotating rod. A sliding groove 3 is provided at the position of the slider at the bottom end of the inner arc wall of the channel 1, and the slider is slidably connected to the sliding groove 3.

[0011] Furthermore, the top of the fixed seat is flush with the top opening of the groove, and the top of the fixed seat is provided with a plurality of slide grooves four distributed in a ring array and arranged along the radial direction of the fixed seat. The end of the slide groove four close to the axis of the fixed seat is slidably connected to the limit block, and the top of the limit block is higher than the top of the fixed seat. A return spring three is fixedly connected to the side wall of the limit block away from the axis of the fixed seat, and the end of the return spring three away from the limit block is fixedly connected to the side wall of the slide groove four.

[0012] Furthermore, the side walls of several of the limit blocks that are close to each other are all inclined surfaces, an eccentric shaft is installed at the bottom of the fixed seat, and the end of the eccentric shaft away from the fixed seat is fixedly connected to a motor, and the motor is located inside the base. When the eccentric shaft drives the fixed seat to rotate, one side of the outer arc wall of the fixed seat is always in contact with the groove.

[0013] Furthermore, two slide grooves are provided on both sides of the top of the outer arc wall of the support rod. The two slide grooves are set through the top of the support rod. A ring is fixedly connected to the bottom of the support plate. A limit strip is fixedly connected to the inner arc wall of the ring, and the limit strip is slidably connected to the second slide groove.

[0014] Compared with the prior art, the beneficial effects of the present invention are:

[0015] Multiple burettes are placed in channel 1 of the turntable, and the analysis bottle is placed in the center of the fixed base, avoiding the burettes from being scattered in the laboratory, thus keeping the work area clean and orderly. During each titration, the turntable is rotated so that the burette can be aligned with the bottle mouth of the analysis bottle. At this time, the operator only needs to operate the burette without having to use both hands to operate two different devices separately, making the titration process more convenient. At the same time, the eccentric motor at the bottom of the fixed base can assist in slightly shaking the analysis bottle, so that the internal solution reacts more fully, ensuring the accuracy of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the overall structure of a drug analysis titration device;

[0017] Figure 2 This is a schematic diagram of the structure of a turntable in a drug analysis titration device;

[0018] Figure 3 for Figure 2 Cross-sectional view of the internal structure at point A;

[0019] Figure 4 This is a schematic diagram of the structure of a fixed seat in a drug analysis titration device.

[0020] In the picture:

[0021] 10. Base; 11. Support rod; 12. Support plate; 13. Counterweight; 14. Burette;

[0022] 20. Turntable; 21. Limiting ring; 22. Limiting bead; 23. Return spring 1;

[0023] 30. Rotating rod; 31. Roller; 32. Slider; 33. Return spring 2;

[0024] 40. Fixed seat; 41. Limit block; 42. Return spring 3. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0026] See also Figure 1-4The utility model provides a technical solution: it includes a base 10 and a support rod 11 connected to one end of the top of the base 10 by a flange, a support plate 12 is sleeved on the outer arc wall of the support rod 11, and a counterweight 13 is fixedly connected to the top of one end of the support plate 12, and an arc-shaped recess is provided at the end of the support plate 12 away from the counterweight 13, and a turntable 20 is rotatably connected in the recess at the end of the support plate 12 away from the counterweight 13, and a plurality of channels 1 distributed in an annular array and passing through the axial direction are opened on the top of the turntable 20, a clamping mechanism is provided in the channel 1, and a burette 14 is provided in the channel 1, and a groove 1 is provided at the top of the base 10 directly below one of the channels 1 away from the counterweight 13, and a fixing seat 40 is provided in the groove 1, and the fixing seat 40 is coaxially arranged with one of the channels away from the counterweight 13;

[0027] The top and bottom ends of the inner arc wall of the recess on the support plate 12 are both provided with a circumferentially penetrating slide groove 1, and the longitudinal section of the slide groove 1 is "丄"-shaped. The top and bottom ends of the outer arc wall of the turntable 20 are fixedly connected to the limit ring 21, which is adapted to the slide groove 1 and slidably connected to the slide groove 1. The outer arc wall of the turntable 20 is provided with a plurality of grooves 2 distributed in a circular array along the radial direction, and a groove 3 is provided on the inner arc wall of the recess on the support plate 12 at a position corresponding to the groove 2.

[0028] A limiting bead 22 is embedded in the groove 2 on the outer arc wall of the turntable 20. A return spring 1 23 is fixedly connected to the side wall of the limiting bead 22 close to the axis of the turntable 20. The elastic direction of the return spring 1 23 is consistent with the radial direction of the turntable 20. The end of the return spring 1 23 away from the limiting bead 22 is fixedly connected to the inner wall of the groove 2. The cross-sectional radius of the end of the inner arc wall of the groove 2 away from the axis of the turntable 20 is smaller than that of the end of the inner arc wall of the groove 2 close to the axis of the turntable 20.

[0029] The support rod 11 has two sliding grooves on both sides of the top of the outer arc wall. The second sliding groove runs through the top of the support rod 11. A ring is fixedly connected to the bottom of the support plate 12. A limit strip is fixedly connected to the inner arc wall of the ring, and the limit strip is slidably connected to the second sliding groove.

[0030] It should be noted that since the burette 14 has a valve for controlling liquid discharge, the cross-section of channel 1 is shaped to match the burette 14. In one possible embodiment, the cross-section of channel 1 is circular at one end near the axis of the turntable 20, and rectangular at one end away from the axis of the turntable 20. That is, the end of channel 1 near the axis of the turntable 20 allows the burette 14 to pass through, while the end of channel 1 away from the axis of the turntable 20 is rectangular to allow the valve assembly to pass through. The clamping mechanism is located on the inner arc wall of the end of channel 1 near the axis of the turntable 20.

[0031] In order to prevent the turntable 20 from falling out of the notch, the longitudinal section of the limiting ring 21 can be "丄"-shaped or "L"-shaped. During installation, the support plate 12 itself is composed of two parts, upper and lower, which are fastened together by multiple bolts. The limiting ring 21 at the bottom end of the turntable 20 can be pre-slid into the slide groove of the lower half of the support plate 12, and then the slide groove of the upper half of the support plate 12 is set on the limiting ring 21 at the top of the turntable 20, and then the two halves of the support plate 12 are fixed with fixing bolts;

[0032] In the initial state, the outer arc wall of the limiting bead 22 is generally located outside the groove 2, and the limiting bead 22 is adapted to the groove 3. The groove 2 can limit the limiting bead 22 to prevent it from being exposed too much and thus unable to reset. In a possible embodiment, there are six grooves 2, and there are three grooves 3 on the inner arc wall of the recess, and the grooves 3 and 2 can correspond to each other. That is, each time the turntable 20 is rotated, the force applied to the turntable 20 is greater than the friction force between the limiting beads 22 and the grooves 3, and the limiting bead 22 will be forced to leave the groove 3. When the limiting bead 22 moves to the next groove 3, the limiting bead 22 will push the reset spring 1 23 to pop out immediately and get stuck in the groove 3.

[0033] At this time, the next burette 14 will move to the center of the fixed seat 40, and so on. Each rotation can accurately rotate the next one to the top of the analysis bottle, which is convenient for the operator to titrate.

[0034] See also Figure 1-4 The present invention provides a technical solution: the clamping mechanism in channel 1 on the turntable 20 includes a rotating rod 30 rotatably connected to the top ends of the inner arc wall of channel 1 on both sides. The two rotating rods 30 are symmetrically arranged about the axis of channel 1. The middle part of the rotating rod 30 and the end of the rotating rod 30 away from the inner arc wall of channel 1 are both rotatably connected to the roller 31;

[0035] The rotating rod 30 is fixedly connected to a side wall of the inner arc wall of the channel 1 at one end away from the rotating connection between the rotating rod 30 and the channel 1, and a reset spring 2 33 is fixedly connected to the slider 32 at one end of the reset spring 2 33 away from the rotating rod 30. A sliding groove 3 is provided at the bottom end of the inner arc wall of the channel 1 corresponding to the position of the slider 32, and the slider 32 is slidably connected to the sliding groove 3.

[0036] It should be noted that when the burette 14 is inserted into the first channel, the wall of the burette 14 abuts against the roller 31. The outer surface of the roller 31 is paved with a flexible material. A torsion spring is provided at the connection between the rotating rod 30 and the inner arc wall of the first channel. The insertion of the burette 14 will squeeze the rotating rod 30 and the roller 31 apart. At the same time, the return spring 2 33 and the slider 32 at the end of the rotating rod 30 will also be pushed, causing them to slide in the third slide groove.

[0037] When the cross-sectional radius of the burette 14 is small, the slider 32 will not abut against the inner wall of the chute 3. When the cross-sectional radius of the burette 14 is large, the slider 32 abuts against the chute 3, and at this time the return spring 2 33 is in an energy storage state, so that the end of the rotating rod 30 also has sufficient force to clamp the burette 14, making the clamping more secure.

[0038] See also Figure 1-4 The present invention provides a technical solution: the top of the fixing seat 40 is flush with the top opening of the groove 1, and the top of the fixing seat 40 is provided with a plurality of slide grooves 4 distributed in an annular array and arranged along the radial direction of the fixing seat 40. The end of the slide groove 4 close to the axis of the fixing seat 40 is slidably connected to the limit block 41, and the top of the limit block 41 is higher than the top of the fixing seat 40. A return spring 3 42 is fixedly connected to the side wall of the limit block 41 away from the axis of the fixing seat 40, and the end of the return spring 3 42 away from the limit block 41 is fixedly connected to the side wall of the slide groove 4;

[0039] The side walls of several of the limit blocks 41 that are close to each other are all inclined surfaces. An eccentric shaft is installed at the bottom of the fixed seat 40. The end of the eccentric shaft away from the fixed seat 40 is fixedly connected to a motor. The motor is located inside the base 10. When the eccentric shaft drives the fixed seat 40 to rotate, one side of the outer arc wall of the fixed seat 40 is always in contact with the groove.

[0040] It should be noted that: when the analysis bottle is placed between the plurality of limit blocks 41, after the bottom of the bottle abuts against the inclined surface of the limit block 41, the limit block 41 will be forced to slide along the slide groove 4, and at the same time, the return spring 3 42 accumulates force, and under the action of the reaction force, the analysis bottle will be pressed tightly, and the eccentric shaft at the bottom of the fixing seat 40 can drive the fixing seat 40 and the analysis bottle thereon to perform eccentric rotation, thereby accelerating the mixing of the solution.

[0041] Working principle:

[0042] First, insert the burette 14 into channel 1. The clamping mechanism can fix the burette 14. Then place the analysis bottle between several limit blocks 41 on the top of the fixing seat 40. Under the action of the inclined surface, the limit block 41 moves outward, but under the action of the return spring 3 42, the limit block 41 will be pushed to move in the opposite direction to fix the analysis bottle. Then manually rotate the turntable 20. Under the action of the limit bead 22 and the return spring 1 23, the turntable 20 will not rotate on its own, but the turntable 20 can be rotated by applying a force from the outside. When the next burette 14 rotates to the top of the analysis bottle, the return spring 1 23 will pop out and get stuck again. In addition, the motor can also drive the fixing seat 40 to do eccentric movement to imitate the shaking action to mix the liquid in the analysis bottle evenly.

Claims

1. A drug analysis titration device, comprising a base (10) and a support rod (11) flange-connected to one end of the top of the base (10), a support plate (12) sleeved on the outer arc wall of the support rod (11), a counterweight (13) fixedly connected to the top of one end of the support plate (12), and an arc-shaped notch provided at the end of the support plate (12) away from the counterweight (13), characterized in that: A turntable (20) is rotatably connected to the notch at one end of the support plate (12) away from the counterweight (13). A plurality of axially penetrating first channels are formed at the top of the turntable (20) and are distributed in an annular array. A clamping mechanism is provided in the first channels, and a burette (14) is provided in the first channels. A first groove is provided at the top of the base (10) directly below one of the first channels away from the counterweight (13). A fixing base (40) is provided in the first groove, and the fixing base (40) is coaxially arranged with one of the first channels away from the counterweight (13).

2. A drug analysis titration device as claimed in claim 1, characterized in that: Circumferentially penetrating first chutes are formed at the top and bottom of the inner arc wall of the notch on the support plate (12). The longitudinal section of the first chute is "丄”-shaped. Limit rings (21) are fixedly connected to the top and bottom of the outer arc wall of the turntable (20). The limit rings (21) are adapted to the first chutes and the limit rings (21) are slidably connected in the first chutes. A plurality of second grooves are formed on the outer arc wall of the turntable (20) in an annular array along the radial direction. Third grooves are formed at the positions corresponding to the second grooves on the inner arc wall of the notch on the support plate (12).

3. A drug analysis titration device as claimed in claim 2, characterized in that: Limit beads (22) are embedded in the second grooves on the outer arc wall of the turntable (20). A first return spring (23) is fixedly connected to one side wall of the limit bead (22) close to the axis of the turntable (20). The elastic direction of the first return spring (23) is consistent with the radial direction of the turntable (20). The end of the first return spring (23) away from the limit bead (22) is fixedly connected to the inner wall of the second groove. The cross-sectional radius of the end of the inner arc wall of the second groove away from the axis of the turntable (r20) is smaller than the end of the inner arc wall of the second groove close to the axis of the turntable (20).

4. A drug analysis titration device as claimed in claim 1, characterized in that: The clamping mechanism in the first channels on the turntable (20) includes rotating rods (30) rotatably connected to the top ends of both sides of the inner arc wall of the first channels. The two rotating rods (30) are symmetrically arranged about the axis of the first channels. Rollers (31) are rotatably connected to the middle of the rotating rods (30) and the ends of the rotating rods (3) away from the inner arc wall of the first channels.

5. A drug analysis titration device as claimed in claim 4, characterized in that: A second return spring (33) is fixedly connected to one side wall of the end of the rotating rod (30) away from its rotating connection with the first channel close to the inner arc wall of the first channel. The end of the second return spring (远离转动杆(30)的一端固定连接有滑块(32),通道一内弧壁底端对应滑块(32)的位置处开设有滑槽三,滑块(32)滑动连接于滑槽三内。) away from the rotating rod (30) is fixedly connected to a slider (32). A third chute is formed at the position corresponding to the slider (32) at the bottom end of the inner arc wall of the first channel. The slider (32) is slidably connected in the third chute.

6. A drug analysis titration device according to claim 1, characterized in that: The top of the fixing base (40) is flush with the top opening of the first groove. A plurality of fourth chutes are formed on the top of the fixing base (40) and are arranged in an annular array along the radial direction of the fixing base (40). A limit block (41) is slidably connected to one end close to the axis of the fixing base (40) in the fourth chute. The top of the limit block (41) is higher than the top of the fixing base (40). A third return spring (42) is fixedly connected to one side wall of the limit block (41) away from the axis of the fixing base (40). The end of the third return spring (42) away from the limit block (41) is fixedly connected to the side wall of the fourth chute.

7. A drug analysis titration device according to claim 6, characterized in that: The side walls of the plurality of limit blocks (41) close to each other are all inclined surfaces, an eccentric shaft is installed at the bottom of the fixed seat (40), and an end of the eccentric shaft away from the fixed seat (40) is fixedly connected to a motor, and the motor is located in the base (10). When the eccentric shaft drives the fixed seat (40) to rotate, one side of the outer arc wall of the fixed seat (40) is always in contact with the groove.

8. A drug analysis titration device as claimed in claim 1, characterized in that: Two slide grooves are provided on both sides of the top of the outer arc wall of the support rod (11). The two slide grooves are set through the top of the support rod (11). A ring is fixedly connected to the bottom of the support plate (12). A limit strip is fixedly connected to the inner arc wall of the ring. The limit strip is slidably connected to the second slide groove.

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