Implant for peri-implantitis experiment of animals

Abstract

The utility model relates to an implant for an animal peri-implantitis experiment, which is characterized in that along the height direction, the bottom surface of a cap body part is connected with the top surface of a neck part, and the area of the bottom surface of the cap body part is larger than that of the top surface of the neck part; in the height direction, the bottom surface of the neck part is connected with the top surface of the limiting part, and the area of the top surface of the limiting part is larger than that of the bottom surface of the neck part; a concave neck part is formed between the cap body part and the limiting part, and a silk thread can be wound on the neck part; the tail part is connected with the bottom surface of the limiting part, the area of the cross section of the limiting part in the horizontal direction is larger than that of the cross section of the tail part in the horizontal direction, and the tail part is used for being implanted into an alveolar bone of an animal. Compared with the prior art, the implant for the periodontitis experiment of the animal implant has the advantages that the probability of periodontitis of experimental animals can be increased, and the success rate of building a periodontitis experimental model is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of implant, especially to an implant for implant peri-implantitis experiment of animal. BACKGROUND

[0002] In recent years, the technology of implant tooth is widely used, and implant tooth refers to a kind of edentulous repair mode based on the lower structure implanted in bone tissue to support and retain upper dental prosthesis. It includes two parts of the lower support implant and the upper dental prosthesis. It is made of artificial materials (such as metal, ceramic, etc.) into implant (generally similar to the shape of tooth root), implanted into tissue (usually maxilla and mandible) by surgical method and obtains firm retention support of bone tissue, and connects the upper dental prosthesis through special device and mode.

[0003] However, in clinic, inflammation may occur around the implant due to the patient's failure to maintain or accompanied by periodontitis, leading to redness and bleeding of the gum around the implant tooth, bone resorption, and peri-implantitis. In order to study the clinical symptoms and treatment methods of peri-implantitis, researchers use animals in the laboratory to establish a peri-implantitis model to observe the clinical symptoms of peri-implantitis and explore the treatment methods of peri-implantitis.

[0004] As disclosed in the Chinese utility model patent with patent number 202222045255.2, a titanium implant for rat maxillary molar area implant tooth model, the implant can be implanted into the rat jaw bone, to simulate the actual clinical environment, to establish an initial stable bone bonding model. However, after the implant is implanted into the rat alveolar bone, the probability of causing peri-implantitis in the rat oral cavity is low, and the efficiency of establishing a peri-implantitis model in the experiment is low, and a large number of experimental samples are wasted. UTILITY MODEL CONTENT

[0005] In view of the above shortcomings of the prior art, in order to improve the success rate of constructing an experimental animal peri-implantitis model, the utility model constructs an implant for animal implant peri-implantitis experiment to achieve the purpose of improving the success rate of constructing an implant peri-implantitis model in animal experiment.

[0006] Based on the above purpose, the utility model provides an implant for animal implant peri-implantitis experiment, the implant comprises a cap body part, a neck part, a limiting part and a tail part arranged from top to bottom along the height direction.

[0007] Along the height direction, the bottom surface of the cap body part is connected with the top surface of the neck part, and the bottom surface area of the cap body part is larger than the top surface area of the neck part.

[0008] The bottom surface of the neck part is connected with the top surface of the limiting part in the height direction, and the area of the top surface of the limiting part is larger than that of the bottom surface of the neck part.

[0009] The neck part is formed between the cap part and the limiting part, and can be used for winding the silk thread.

[0010] The tail part is connected with the bottom surface of the limiting part, the cross-sectional area of the limiting part in the horizontal direction is larger than that of the tail part in the horizontal direction, and the tail part is used for implanting into the alveolar bone of the animal.

[0011] Further, the cap part, the neck part and the limiting part form a "H" shape structure in the height direction of the implant.

[0012] Further, the neck part is a smooth cylinder.

[0013] Further, the cap part is a prism, a D-shaped column or a star-shaped column.

[0014] Further, the cap part and the limiting part are prisms, D-shaped columns or star-shaped columns with the same shape, size and angular orientation.

[0015] Further, the prism is a four-prism or a six-prism.

[0016] Further, the height of the neck part is 200-400 microns.

[0017] Further, the height from the top surface of the cap part to the bottom surface of the limiting part is 400-600 microns.

[0018] Further, the implant is an integral structure.

[0019] Further, the free end of the tail part is a sharp blade, and the surface of the implant is provided with a self-tapping thread.

[0020] Different from the prior art, the implant is additionally provided with an implant neck part and an implant limiting part under the cap part, the tail part is implanted into the alveolar bone, the limiting part abuts against the alveolar bone, the limiting part, the neck part and the cap part are exposed above the alveolar bone, the implant neck part forms a groove between the cap part and the implant limiting part, and the groove structure can be used for winding the silk thread. In use, the implant is screwed into the alveolar bone in the oral cavity of the experimental animal, the silk thread is wound on the implant neck part to make the bacteria in the oral cavity accumulate and further invade the soft tissue and the bone, so that the periodontitis is more easily generated. Compared with the animal periodontitis experiment implant of the prior art, the implant can increase the probability of periodontitis generation of the experimental animal and improve the success rate of constructing the periodontitis experiment model. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 is a perspective view of a kind to be used for the implant of the peri-implantitis experiment of animal of this embodiment implant;

[0022] Figure 2 is a front view of a kind to be used for the implant of the peri-implantitis experiment of animal of this embodiment implant;

[0023] Figure 3 is a top view of a kind to be used for the implant of the peri-implantitis experiment of animal of this embodiment implant;

[0024] Figure 4 is a front view of the cap body, neck and limiting part of this embodiment;

[0025] Figure 5 is a three-dimensional perspective view of the coordinate axis of the cap body, neck and limiting part of this embodiment.

[0026] Marking of drawing:

[0027] 1, cap body; 2, neck; 3, limiting part; 4, tail; 41, outer screw thread; 42, sharp blade part. DETAILED DESCRIPTION

[0028] In order to make possible application scene, technical principle, specific scheme that can be implemented, purpose and effect that can be achieved of the present application more clear, the following will be combined with the specific embodiments listed and cooperate with the drawings detailed description.The embodiments recorded in this paper are only used to more clearly illustrate the technical scheme of the present application, therefore only as an example, and can not limit the protection scope of the present application.

[0029] In this paper, "embodiment" means that the specific features, structures or characteristics described in conjunction with the embodiment can be included in at least one embodiment of the present application.The word "embodiment" appearing in various places in the specification does not necessarily refer to the same embodiment, and does not particularly limit the independence or association between other embodiments.In principle, in the present application, as long as there is no technical contradiction or conflict, the technical features mentioned in each embodiment can be combined in any way to form a corresponding implementable technical scheme.

[0030] Unless otherwise defined, the meaning of the technical terms used in this paper is the same as that generally understood by the person skilled in the art to which the present application belongs;The use of related terms in this paper is only for the description of specific embodiments, and is not intended to limit the present application.

[0031] In the description of the present application, the word "and / or" is a description of the logical relationship between the objects, which means that there are three kinds of relationships, for example, A and / or B, which means that there are three kinds of situations, that is, A exists, B exists, and A and B exist at the same time.In addition, the character " / " in this paper generally represents that the associated objects before and after are a kind of "or" logical relationship.

[0032] In the present application, the terms such as "first" and "second" are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual number, primary or secondary, or order relationship between the entities or operations.

[0033] In the present application, the "includes", "contains", "has", or other similar expressions used in the statements are intended to cover non-exclusive inclusion, and do not exclude the presence of additional elements in the process, method or product comprising the elements, so that the process, method or product comprising a series of elements can not only include those defined elements, but also include other elements not explicitly listed, or also include elements inherent to such process, method or product.

[0034] As the same understanding as in the "Guidelines for Examination", in the present application, the expressions such as "greater than", "less than", "exceed" are understood as not including the number; the expressions such as "above", "below", "within" are understood as including the number. In addition, in the description of the embodiments of the present application, the meaning of "multiple" is more than two (including two), and similar expressions related to "multiple" are also understood in this way, for example, "multiple groups", "multiple times", etc., unless otherwise explicitly specified.

[0035] In the description of the embodiments of the present application, the spatial-related expressions used, such as "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "perpendicular", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. The indicated orientation or position relationship is based on the orientation or position relationship shown in the specific embodiment or the drawing, and is only for the convenience of describing the specific embodiments of the present application or for the reader to understand, and does not indicate or imply that the indicated device or component must have a specific position, a specific orientation, or be constructed or operated in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present application.

[0036] Unless otherwise explicitly specified or limited, in the description of the embodiments of the present application, the terms "mount", "connect", "connect", "fix", "set", etc. should be understood in a broad sense. For example, the "connection" can be a fixed connection, or a detachable connection, or an integral setting; it can be directly connected, or indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art to which the present application belongs, the specific meaning of the above terms in the embodiments of the present application can be understood according to the specific circumstances.

[0037] Clearly, the described embodiments are merely a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the present application.

[0038] The prior art implant is implanted into the jaw bone of a rat or other experimental animal to simulate a clinical actual environment to establish an initial stable bone bonding model, but the existing implant has a low probability of causing peri-implantitis in the oral cavity of a rat after being implanted into the alveolar bone of the rat. The inventor believes through observation and thinking that the reason is that the surface of the existing implant is difficult to attach and breed bacterial contaminants, and thus it is difficult to cause peri-implantitis. The inventor conceives to set a structure capable of winding a silk thread on the implant structure, the silk thread can cause bacteria in the oral cavity to accumulate and further invade soft tissue and bone, thereby more easily causing periodontitis to occur. Based on this, the inventor designs the following embodiments related to the present application.

[0039] Please refer to Figure 1 The present embodiment provides an implant for peri-implantitis experiment of an animal, the implant comprises a cap body part 1, a neck part 2, a limiting part 3, and a tail part 4 arranged from top to bottom;

[0040] In the height direction, the bottom surface of the cap body part is connected with the top surface of the neck part, and the bottom surface area of the cap body part is greater than the top surface area of the neck part;

[0041] In the height direction, the bottom surface of the neck part is connected with the top surface of the limiting part, and the top surface area of the limiting part is greater than the bottom surface area of the neck part;

[0042] The cap body part and the limiting part form a recessed neck part therebetween for winding a silk thread;

[0043] The tail part is connected with the bottom surface of the limiting part, the cross-sectional area of the limiting part in the horizontal direction is greater than the cross-sectional area of the tail part in the horizontal direction, and the tail part is used for implanting into the alveolar bone of the animal.

[0044] The bottom surface of the cap body part 1 in the vertical direction is connected with the top surface of the neck part 2 in the vertical direction, the bottom surface area of the cap body part 1 is greater than the top surface area of the neck part 2, the bottom surface of the neck part 2 in the vertical direction is connected with the top surface of the limiting part 3 in the vertical direction, the top surface area of the limiting part 3 is greater than the bottom surface area of the neck part 2, the cap body part 1 and the limiting part 2 form a recessed neck part 2 therebetween for winding a silk thread, and the tail part 4 is connected with the bottom surface of the limiting part 3 for implanting into the alveolar bone of the animal.

[0045] In some embodiments, the material of the implant is titanium metal, and in other embodiments, the material of the implant can also be cobalt-chromium alloy, tantalum, bioceramics, etc.

[0046] The neck 2 is formed between the cap body 1 and the limiting portion 3. In the experiment of constructing the peri-implantitis model, after the implant is implanted into the alveolar bone in the oral cavity for about six weeks and the implant and the alveolar bone complete the bone integration, the silk thread can be wound in the recessed neck 2. Since the two ends of the neck 2 are the cap body 1 and the limiting portion 3 which are larger than the neck, the silk thread wound in the neck 2 is not easy to be pulled out from the cap body 1 above the neck 2, and the silk thread can accumulate bacteria in the oral cavity, thereby infecting the soft tissue and the bone and causing peri-implantitis.

[0047] In order to more accurately control the implantation depth of the implant, in some embodiments, the cross-sectional area of the bottom surface of the limiting portion is larger than the cross-sectional area of the tail portion; therefore, during the implantation of the tail portion 4 into the alveolar bone, since the area of the bottom surface of the limiting portion 2 is larger than the area of the tail portion, when the implantation depth of the implant reaches the position where the limiting portion 3 abuts against the upper surface of the alveolar bone, the implant cannot be implanted any further downward, and in this process, the limiting portion 3 plays a role of abutment, which facilitates the operator to observe whether the screwing is in place, so as to accurately control the implantation depth of the implant and improve the accuracy and consistency of the experiment.

[0048] In some embodiments, as shown in Figure 1 , the cap body 1, the neck 2 and the limiting portion 3 form a “H-shaped” structure in the height direction of the implant. That is, in the longitudinal cross-section passing through the central axis of the implant, the cap body 1, the neck 2 and the limiting portion 3 of the implant form a “H-shaped” structure. The “H-shaped” structure is more stable and convenient to process compared with other structures, and in other embodiments, as shown in Figure 4 , the upper surface and the lower surface of the neck can also be connected to any position of the lower surface of the cap body and the upper surface of the limiting portion respectively, that is, the central axis of the neck 2 can not need to be aligned with the geometric center axis of the cap body 1, and the central axis of the neck 2 can also not need to be aligned with the geometric center axis of the limiting portion 3, as long as the neck 2 forms a groove between the cap body 1 and the limiting portion 3.

[0049] In some embodiments, as shown in Figures 1 to 3 , the neck 2 of the implant is a smooth cylinder. The smooth cylindrical surface has no edges, and the silk thread is not easy to be cut by the edges, so that the winding of the silk thread has stability. In other embodiments, the neck 2 of the implant can also be a smooth circular truncated cone.

[0050] In some embodiments, the cap portion 1 is a prism, a D-shaped column or a star-shaped column. The cap portion 1 is used to implant the implant into the alveolar bone by screwing the cap portion, and the prism, the D-shaped column or the star-shaped column can be screwed by using a corresponding internal recessed wrench, which can provide a torque force with less effort and can be more convenient to screw than a traditional one-word or cross-shaped opening. In other embodiments, the cap portion 1 can also be a prism, a D-shaped column or a star-shaped column, which can be screwed by using a corresponding internal recessed wrench.

[0051] In some embodiments, as shown in FIG. 1, the cap portion 1 and the limiting portion 3 are prisms, D-shaped columns or star-shaped columns with the same shape, size and angular orientation. Figure 5 In some embodiments, as shown in FIG. 1, the cap portion 1 and the limiting portion 3 are prisms, D-shaped columns or star-shaped columns with the same shape, size and angular orientation.

[0052] In some embodiments, as shown in FIG. 1, the cap portion 1 and the limiting portion 3 are prisms, D-shaped columns or star-shaped columns with the same shape, size and angular orientation. Figure 1 In some embodiments, as shown in FIG. 1, the cap portion 1 and the limiting portion 3 are prisms, D-shaped columns or star-shaped columns with the same shape, size and angular orientation.

[0053] In some embodiments, the height of the neck portion 2 is 200-400 microns. In actual experimental operations, rats are selected as experimental animals, and an implant peri-implantitis model is constructed in the oral cavity of the rats. According to the size of the oral cavity of the rats and the size of the teeth of the rats, the height of the neck portion 2 of the selected implant is 200-400 microns, which is suitable for experiments. In other embodiments, other animals are selected as experimental animals for implant peri-implantitis model culture experiments, and the size of the neck portion 2 of the implant is determined according to the size of the oral cavity and the teeth of the selected animals.

[0054] In some embodiments, the height of the neck portion 2 is 200-400 microns. In actual experimental operations, rats are selected as experimental animals, and an implant peri-implantitis model is constructed in the oral cavity of the rats. According to the size of the oral cavity of the rats and the size of the teeth of the rats, the height of the neck portion 2 of the selected implant is 200-400 microns, which is suitable for experiments. In other embodiments, other animals are selected as experimental animals for implant peri-implantitis model culture experiments, and the size of the neck portion 2 of the implant is determined according to the size of the oral cavity and the teeth of the selected animals.

[0055] In some embodiments, the implant is a one-piece structure, which is more stable during implantation. In other embodiments, the implant is a cast-welded structure.

[0056] In some embodiments, the free end of the tail 4 is a sharp blade, and the implant surface is provided with self-tapping external threads 41. The free end of the tail 4 refers to the end thereof away from the neck. By screwing the implant cap 1, the tail 4 is implanted into the alveolar bone, and the sharp blade 42 of the tail end of the implant pierces the alveolar bone, and the implant is implanted into the alveolar bone by the self-tapping external threads 41 under the action of screwing, so that the implant can be implanted into the alveolar bone to obtain firm retention support of the bone tissue.

[0057] Finally, it should be noted that although the above embodiments have been described in the specification and drawings of the present application, the patent protection scope of the present application should not be limited thereby. Any technical solutions obtained by replacing or modifying the equivalent structures or equivalent processes based on the essential concept of the present application, using the contents described in the specification and drawings of the present application, and directly or indirectly implementing the technical solutions of the above embodiments in other related technical fields, etc., are all included in the patent protection scope of the present application.

Claims

1. An implant for use in an animal peri-implantitis experiment, characterized in that: The implant comprises a cap portion, a neck portion, a limiting portion, and a tail portion which are arranged from top to bottom along the height direction; In the height direction, the bottom surface of the cap body is connected to the top surface of the neck, and the bottom surface area of ​​the cap body is larger than the top surface area of ​​the neck; In the height direction, the bottom surface of the neck is connected to the top surface of the limiting portion, and the area of ​​the top surface of the limiting portion is larger than the area of ​​the bottom surface of the neck; A concave neck is formed between the cap body and the limiting portion for winding of the thread; The tail is connected to the bottom surface of the limiting portion, the cross-sectional area of ​​the limiting portion along the horizontal direction is larger than the cross-sectional area of ​​the tail along the horizontal direction, and the tail is used to be implanted in the alveolar bone of an animal.

2. The implant for animal peri-implantitis experiments according to claim 1, characterized in that: The cap body, neck and limiting portion form an "I-shaped" structure in the height direction of the implant.

3. The implant for animal peri-implantitis experiments according to claim 2, characterized in that: The neck is a smooth cylinder.

4. The implant for animal peri-implantitis experiments according to claim 1, characterized in that: The cap body is in the shape of a prism, a D-shaped column or a star-shaped column.

5. The implant for animal peri-implantitis experiments according to claim 4, characterized in that: The cap body and the limiting portion are prism-shaped, D-shaped or star-shaped columns with the same shape, size and angle orientation.

6. The implant for animal peri-implantitis experiments according to claim 4 or 5, characterized in that: The prism shape is a quadrangular prism or a hexagonal prism.

7. The implant for animal peri-implantitis experiments according to claim 1, characterized in that: The height of the neck is 200-400 microns.

8. The implant for animal peri-implantitis experiments according to claim 7, characterized in that: The height from the top surface of the cap body to the bottom surface of the limiting portion is 400-600 microns.

9. The implant for animal peri-implantitis experiments according to claim 1, characterized in that: The implant is an integrally formed structure.

10. The implant for animal peri-implantitis experiments according to claim 1, characterized in that: The free end of the tail is in the shape of a sharp blade, and the surface of the implant is provided with a self-tapping thread.

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