Efficient freeze-drying freeze dryer sterile transfer tray for penicillin bottles

Abstract

The utility model discloses an efficient freeze-drying sterile transfer tray of a freeze dryer for penicillin bottles, and aims to solve the problem of low heat exchange efficiency due to a small gap between the plane of the conventional tray and a heat conducting plate of the freeze dryer. In order to solve the problem that a penicillin bottle in a semi-plugged state is not completely closed and has the risk of sample pollution in the transfer process, the following scheme is provided: the penicillin bottle packaging device comprises a mold, a base and a cover, a placement cavity is formed in the mold, the cover is arranged at the top of the mold, strip-shaped grooves are formed in the inner walls of the two sides of the placement cavity, and the strip-shaped grooves are arranged in the mold. The sample transfer device is composed of the cover, the mold and the base, the three parts are of a mutually detachable embedded structure, it is ensured that a sample does not make contact with the external environment in the transfer process, and it is ensured that the sample is sterile. All the devices can be completely withdrawn after transfer is completed, so that the penicillin bottles can be completely contacted with the heat conducting plate, the heat exchange efficiency is high, the vacuum drying efficiency is improved, and meanwhile, observation on samples in the freeze drying process is not influenced.

Description

TECHNICAL FIELD

[0001] The utility model relates to tray technical field especially relates to a high -efficient freeze -drying's sterile transfer tray for freeze -drying machine of westlin bottle. BACKGROUND

[0002] Westlin bottle is a kind of small bottle with rubber plug and aluminium plastic combined cover sealing.The early penicillin is mostly filled in it, so it is named westlin bottle, and brown, transparent and borosilicate westlin bottle are the mainstream products in market.

[0003] Vacuum freeze-drying technology is especially suitable for the preparation of heat-sensitive materials due to its low process temperature and high drying efficiency, and the appearance, color, flavor and active nutrients of the freeze-dried products remain basically unchanged, and the rehydration is rapid, the shelf life is long, and the transportation and storage are very convenient, so it is widely used in the fields of medicine, biological products, blood products, etc.

[0004] However, its temperature transfer is poor in vacuum state, which hinders its development. At present, most of the freeze-drying machines use stainless steel transfer trays, which are directly placed on the heat transfer plate of the freeze-drying machine for freeze-drying. However, due to the small gap between the tray plane and the heat transfer plate, heat transfer can only be transferred through the contact between the westlin bottle and the tray plane under the extremely high vacuum condition in the vacuum freeze-drying process, and the heat transfer is poor in the gap, which greatly affects the freezing efficiency.

[0005] The freeze-drying process of westlin bottle filled with medicine is usually carried out in a sterile operation table. After the medicine is divided and filled in the westlin bottle, the westlin bottle is semi-closed, and then the westlin bottle is transferred to the vacuum freeze-drying machine for freeze-drying. Since the westlin bottle is semi-closed, the sample solution is exposed to the external environment during the transfer process, which has a high risk of contamination. UTILITY MODEL CONTENTS

[0006] The utility model discloses a kind of sterile transfer trays for freeze-drying machine of westlin bottle to solve the problem that the tray plane and the heat transfer plate exist small gap in prior art, under the extremely high vacuum condition in the vacuum freeze-drying process, heat transfer can only be transferred through the contact between the tray plane and the heat transfer plate, westlin bottle is contacted with the tray plane again to transfer, and the heat transfer is poor in the gap, which greatly affects the freezing efficiency. Since the westlin bottle is semi-closed, the sample solution is exposed to the external environment during the transfer process, which has a high risk of contamination.

[0007] To achieve the above object, the utility model adopts the following technical scheme:

[0008] The utility model provides a high -efficient freeze -drying vial freeze dryer sterile transfer tray, including mould, base and lid, the inside of mould is provided with the cavity, the lid sets up in the top of mould, both side inner walls of cavity are provided with strip groove, the base is inserted in the inside of strip groove and slides, the inside of cavity is fixedly connected with a plurality of longitudinal partition and a plurality of horizontal partition, a plurality of horizontal partition and a plurality of longitudinal partition are vertically arranged, the space between horizontal partition and longitudinal partition is placed with vial.

[0009] In a possible design, one side of the mold is provided with a handle, and one side of the base is provided with a rectangular plate.

[0010] In a possible design, the top of the base is integrally formed with a protrusion, and the side of the cavity is provided with a recess in communication. The recess is used in cooperation with the protrusion.

[0011] In a possible design, the top of the mold is provided with a mounting frame, which is used in cooperation with the lid.

[0012] In a possible design, two legs are symmetrically arranged, and the two legs are fixedly connected to the two sides of the mold, respectively. A limiting rod is slidably penetrated into the inside of the leg, and a limiting block is fixedly connected to the top of the limiting rod.

[0013] In a possible design, the bottom of the limiting rod is fixedly connected with a circular plate, and the bottom of the circular plate is provided with a suction cup.

[0014] In this application,

[0015] 1. The components of the high -efficient freeze -drying vial freeze dryer sterile transfer tray, including the lid, the mold, and the base, are cleaned, high-temperature high-pressure or irradiation sterilized to ensure that the sterile process requirements are met when used;

[0016] 2. In a sterile operation table, the base and the mold of the high -efficient freeze -drying vial freeze dryer sterile transfer tray are combined, and the vials are placed in the fixed position in the mold. The sample is sterilely divided and distributed, and the vial is half-capped;

[0017] 3. After the sample is distributed, the lid is covered, and the sterile tray containing the sample is transferred to the appropriate position on the heat conduction plate in the cleaned freeze dryer. The base of the transfer tray is carefully pulled out;

[0018] 4. After the vials are stable, the mold is slowly lifted vertically together with the lid until the mold is completely separated from the vials. The mold can be moved in a vertical state by cooperating with the leg and the limiting rod. The suction cup is arranged to fix the leg. After the mold is removed, the device is removed as a whole;

[0019] 5. Close the freeze dryer door, set the freeze drying program, and start the freeze drying.

[0020] Advantages:

[0021] In the utility model, the lid and the base are set, sealing is realized, the external environment is isolated during the transfer of the westlin bottle, and the pollution risk effect is reduced.

[0022] In the utility model, after the transfer is completed, all the devices can be completely removed, the westlin bottle is completely in contact with the drying heat conduction plate, the heat exchange efficiency is high, and the vacuum drying efficiency is improved.

[0023] In the utility model, the lid, the mold and the base are three parts, the three parts are detachably embedded structures, the sample is prevented from contacting the external environment during the transfer, the sterility of the sample is ensured, after the transfer is completed, all the devices can be completely removed, the westlin bottle can be completely in contact with the drying heat conduction plate, the heat exchange efficiency is high, the vacuum drying efficiency is improved, the observation of the sample during the freeze drying process is not affected, the distance between the multiple westlin bottles is well ensured, the drying process is facilitated, the westlin bottle is prevented from contacting the external environment, and the sterile environment of the westlin bottle is ensured. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 A three-dimensional structure schematic view of the utility model is provided.

[0025] Figure 2 An explosion structure schematic view of the utility model is provided.

[0026] Figure 3 An explosion structure schematic view of the mold and the partition plate in the utility model is provided.

[0027] Figure 4 A three-dimensional structure schematic view of the utility model is provided.

[0028] In the drawing: 1, mold; 2, protrusion; 3, rectangular plate; 4, handle; 5, lid; 6, mounting frame; 7, base; 8, strip-shaped groove; 9, recess; 10, transverse partition plate; 11, longitudinal partition plate; 12, placing cavity; 13, limiting block; 14, limiting rod; 15, supporting leg; 16, round plate; 17, suction cup. DETAILED DESCRIPTION

[0029] Clearly, the described embodiments are merely a part of the embodiments of the present application, rather than all the embodiments.

[0030] Embodiment 1

[0031] With reference to Figure 1-4 A tray, comprising: a mold 1, a base 7 and a cover 5, the sterile transfer tray for high-efficiency freeze-dried penicillin bottles is used to clean, high-temperature high-pressure or irradiation sterilization of each component, including the cover 5, the mold 1, the base 7, to ensure that the sterile process requirements are met when used, the inside of the mold 1 is provided with a placing cavity 12, the cover 5 is arranged on the top of the mold 1, strip grooves 8 are arranged on the inner walls of both sides of the placing cavity 12, the base 7 is slidingly inserted into the inside of the strip groove 8, a plurality of longitudinal partitions 11 and a plurality of transverse partitions 10 are fixedly connected in the inside of the placing cavity 12, the plurality of transverse partitions 10 and the plurality of longitudinal partitions 11 are arranged vertically, the space between the transverse partitions 10 and the longitudinal partitions 11 is arranged with penicillin bottles, in the sterile operation table, the base 7 and the mold 1 of the sterile transfer tray for high-efficiency freeze-dried penicillin bottles are combined, and the penicillin bottles are placed in the fixed position in the mold 1, sample sterile dispensing and half-closing of the penicillin bottles are carried out, one side of the mold 1 is provided with a handle 4, one side of the base 7 is provided with a rectangular plate 3, after the sample dispensing is completed, the cover 5 is closed, the sterile tray containing the sample is transferred to a proper position on the heat-conducting plate in the cleaned freeze-dryer, the base 7 of the transfer tray is carefully pulled out, the top of the base 7 is integrally formed with a protrusion 2, a recess 9 is arranged on one side of the placing cavity 12, the recess 9 is used in cooperation with the protrusion 2, and the top of the mold 1 is provided with a mounting frame 6. The mounting frame 6 is used in cooperation with the cover 5.

[0032] The present application can be used in the field of penicillin bottles, and can also be applied to other fields of the present application.

[0033] Embodiment 2

[0034] With reference to Figure 1-4On the basis of embodiment 1, improve: a kind of high-efficiency freeze-drying freeze-drying machine sterile transfer tray for vial, it is applied in vial field, it further includes two symmetrical legs 15, two symmetrical legs 15 are respectively fixedly connected in the two sides of mould 1, the inside of leg 15 is slidably penetrated by limiting rod 14, the top of limiting rod 14 is fixedly connected with limiting block 13, the bottom of limiting rod 14 is fixedly connected with round plate 16, the bottom of round plate 16 is provided with suction cup 17, after vial is stable, mould 1 is slowly vertically taken together with cover 5, until mould 1 is completely separated from vial, it can be cooperated with leg 15 and limiting rod 14, ensure that mould 1 is in vertical state when moving, the setting of suction cup 17 is used to fix leg 15, after mould 1 is removed, the device is removed as a whole, freeze-drying machine hatch is closed, freeze-drying program is set, and freeze-drying is started.

[0035] The above is only the preferred embodiment of the present application, but the protection scope of the present application is not limited to this, any person skilled in the art can replace or change the technical scheme and the inventive concept of the present application according to the technical range disclosed in the present application, which should be covered in the protection scope of the present application.

Claims

1. A sterile transport tray for a freeze dryer for efficient freeze-drying of vials, characterized in that: The invention comprises a mold (1), a base (7) and a cover (5); a placement cavity (12) is provided inside the mold (1); the cover (5) is arranged on the top of the mold (1); strip grooves (8) are provided on both inner walls of the placement cavity (12); the base (7) is slidably inserted into the strip grooves (8); a plurality of longitudinal partitions (11) and a plurality of transverse partitions (10) are fixedly connected inside the placement cavity (12); the plurality of transverse partitions (10) and the plurality of longitudinal partitions (11) are vertically arranged; and a vial is placed in the space between the transverse partitions (10) and the longitudinal partitions (11).

2. The sterile transport tray for a freeze dryer for efficiently freeze-dried vials according to claim 1, characterized in that: A handle (4) is provided on one side of the mold (1), and a rectangular plate (3) is provided on one side of the base (7).

3. The sterile transport tray for a freeze dryer for efficiently freeze-dried vials according to claim 1, characterized in that: A protrusion (2) is integrally formed on the top of the base (7), and a communicating groove (9) is provided on one side of the placement cavity (12), and the groove (9) is used in conjunction with the protrusion (2).

4. The sterile transport tray for a freeze dryer for efficiently freeze-dried vials according to claim 1, characterized in that: A mounting frame (6) is provided on the top of the mold (1), and the mounting frame (6) is used in conjunction with the cover (5).

5. The sterile transport tray for a freeze dryer for efficiently freeze-dried vials according to claim 1, characterized in that: It also includes two symmetrically arranged supporting legs (15), the two supporting legs (15) are respectively fixedly connected to the two sides of the mold (1), the interior of the supporting legs (15) slides through the limiting rod (14), and the top of the limiting rod (14) is fixedly connected to the limiting block (13).

6. The sterile transport tray for a freeze dryer for efficiently freeze-dried vials according to claim 5, characterized in that: The bottom of the limiting rod (14) is fixedly connected to a circular plate (16), and the bottom of the circular plate (16) is provided with a suction cup (17).

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