Dry-wet separation reagent bottle and analyzer

By designing reagent bottles that separate wet and dry components, the automatic reconstitution of lyophilized reagents is achieved through the rotation of the push and puncture parts. This solves the problems of tedious reconstitution of lyophilized reagents and high labor costs, improves work efficiency, and reduces cleaning burden.

CN223467576UActive Publication Date: 2025-10-24SHENZHEN KEMAN BIOMEDICAL CO LTD
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Patent Information

Application Number
CN202422002521.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-16
Publication Date
2025-10-24
Estimated Expiration
2034-08-16

AI Technical Summary

Technical Problem

The existing reconstitution process for lyophilized reagents requires manual operation, which is cumbersome, time-consuming, and labor-intensive. Furthermore, it requires precise dosage of buffer solution, resulting in low work efficiency.

Method used

A reagent bottle with dry and wet separation was designed. The bottle body and the cap are rotatably connected. The cap has a cavity for holding the reconstitution buffer. A pressing component drives a piercing component to rotate and puncture the sealing component, allowing the buffer to flow into the lyophilized powder, so that reconstitution can be achieved with a single press and rotation.

Benefits of technology

It simplifies the reconstitution process of lyophilized reagents, reduces human error, improves work efficiency, reduces the use of experimental equipment, and reduces the cleaning burden.

✦ Generated by Eureka AI based on patent content.

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Abstract

The dry-wet separation reagent bottle comprises a bottle body, a bottle cap, a pressing piece, a puncturing piece and a sealing piece, the bottle body is rotatably connected with the bottle cap, the bottle body is provided with a placing cavity and a bottle opening communicated with the placing cavity, freeze-dried powder is placed in the placing cavity, the bottle cap is provided with an opening, and the opening is communicated with the bottle opening. The sealing part is installed at the opening, the sealing part and the bottle cap define a containing cavity, a redissolving buffer solution is placed in the containing cavity, the pressing part is installed on the bottle cap, the puncturing part is arranged in the containing cavity and connected with the pressing part, the pressing part is pressed to drive the puncturing part to move towards the sealing part, the bottle cap is rotated to drive the pressing part and the puncturing part to rotate, and the sealing part and the bottle cap are sealed. The pressing piece is arranged to drive the puncturing piece to move, and the bottle cap drives the puncturing piece to rotate, so that the sealing piece can be scratched, freeze-dried powder can be redissolved through the action of pressing and rotating, operation is easy and convenient, the problem of manual operation errors is solved, and therefore the working efficiency is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to test equipment technical field especially relates to a reagent bottle and analyzer of dry and wet separation. BACKGROUND

[0002] At present, the quality control / calibration product of the item detected by biochemical / luminous analyzer in the laboratory is mostly freeze-dried reagent, and the freeze-dried reagent needs to be reconstituted before use; ear bulb is used to suck the buffer solution of corresponding dose, the ear bulb is loosened, the top of the glass suction tube is pressed by fingers, the fingers are loosened, the excess buffer solution in the suction tube is discharged to be tangent to the scale line of the suction tube, the head of the suction tube is aligned with the reagent bottle mouth, the fingers are loosened, and the buffer solution is naturally flowed into the reagent bottle, one suction tube only sucks one reagent, and after use, the suction tube is immersed in water immediately.

[0003] However, the reconstitution process of the whole freeze-dried reagent is artificial, the operation is very tedious, the labor cost is too high, the dose of the buffer solution added for reconstitution is required to be accurate, the artificial experimental method is required to be too high, and therefore the working efficiency is low. UTILITY MODEL CONTENT

[0004] Therefore, it is necessary to provide a reagent bottle and analyzer of dry and wet separation, which aims to solve the technical problems that the reconstitution process of the whole freeze-dried reagent is artificial, the operation is very tedious, the labor cost is too high, the dose of the buffer solution added for reconstitution is required to be accurate, the artificial experimental method is required to be too high, and therefore the working efficiency is low.

[0005] In a first aspect, the utility model provides a reagent bottle of dry and wet separation, which comprises:

[0006] A bottle body is provided with a placing cavity and a bottle mouth in communication with the placing cavity, and the freeze-dried powder is placed in the placing cavity;

[0007] A bottle cap is provided with an opening and is rotationally connected with the bottle body;

[0008] A pressing member is installed on the bottle cap;

[0009] A closing member is installed at the opening and forms a containing cavity with the bottle cap, and the reconstitution buffer solution is placed in the containing cavity;

[0010] A piercing member is arranged in the containing cavity and connected with the pressing member;

[0011] The pressing member is pressed to drive the piercing member to move towards the closing member, and the bottle cap is rotated to drive the pressing member and the piercing member to rotate, the piercing member pierces the closing member, so that the reconstitution buffer solution flows into the placing cavity from the opening through the bottle mouth.

[0012] In one embodiment, the push member is installed at the edge of the bottle cap.

[0013] In one embodiment, the push member is a structural member made of elastic rubber.

[0014] In one embodiment, the push member protrudes from the bottle cap.

[0015] In one embodiment, the piercing member and the pressing member are arranged at an angle.

[0016] In one embodiment, the piercing member includes an extension portion and a piercing portion connected to the extension portion, and the piercing portion is provided with an inclined surface.

[0017] In one embodiment, the plane where the inclined surface is located is perpendicular to the closing member.

[0018] In one embodiment, the bottle body is provided with an external thread or an internal thread, the bottle cap is provided with an external thread or an internal thread, and the bottle body and the bottle cap are threadedly connected.

[0019] In one embodiment, the piercing member is a structural member made of plastic material.

[0020] In a second aspect, the present invention also provides an analyzer, which includes a reagent rack, an analysis module, a transfer module, and dry-wet separation reagent bottles of any of the above embodiments, wherein the reagent bottles are placed on the reagent rack, the transfer module is used to transfer the reagent rack to the analysis module, and the analysis module is used to analyze the reagents in the reagent bottles.

[0021] The implementation of the present invention will have the following beneficial effects:

[0022] The bottle cap is provided with an opening, and the sealing member is installed at the opening and is surrounded by the bottle cap to form a receiving chamber, wherein a reconstitution buffer is placed in the receiving chamber, and the pressing member is installed in the bottle cap, and the piercing member is arranged in the receiving chamber and is connected with the pressing member. When the pressing member is pressed, the piercing member moves toward the piercing member, and the bottle cap is rotated to drive the pressing member and the piercing member to rotate, and the piercing member cuts the piercing member to allow the reconstitution buffer to flow from the opening through the bottle mouth into the receiving chamber, so that the reconstitution buffer is mixed with the freeze-dried powder. The pressing member drives the piercing member to move, and the bottle cap drives the piercing member to rotate, so that the piercing member can be cut, and the freeze-dried powder can be reconstituted by a one-press-one-turn action, which is simple to operate and solves the human error in operation, thereby improving work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings described below are only some of the embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0024] Among them:

[0025] Figure 1 It is a shaft measurement schematic diagram of the reagent bottle for dry-wet separation in an embodiment.

[0026] Reference signs:

[0027] 1, bottle body; 11, placement cavity; 12, bottle mouth;

[0028] 2, bottle cap; 21, opening; 22, containing cavity;

[0029] 3, pressing member;

[0030] 4, puncture member; 41, extension; 42, puncture part; 421, inclined surface;

[0031] 5, closure; 100, freeze-dried powder. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the present application will be described clearly and completely below in combination with the drawings of the embodiments of the present application. Obviously, the described embodiments are only some of the embodiments of the present application, not all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0033] It should be noted that: similar reference numbers and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings.

[0034] In the description of the present application, it should be noted that if the terms "upper", "lower", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship of the product of the present application when it is usually placed, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as a limitation on the present application.

[0035] In addition, if the terms "first", "second" or the like are used herein, they are used only for distinguishing the description and cannot be understood as indicating or implying relative importance.

[0036] It should be noted that the features in the embodiments of the present application can be combined with each other without conflict.

[0037] Please combine Figure 1 The dry and wet separation reagent bottle provided by the present application will be described, which is used in an analyzer.

[0038] The dry and wet separation reagent bottle comprises a bottle body 1, a bottle cap 2, a pressing member 3, a piercing member 4 and a sealing member 5. The bottle body 1 and the bottle cap 2 are rotatably connected. The bottle body 1 is provided with a placing cavity 11 and a bottle mouth 12 in communication with the placing cavity 11. The freeze-dried powder 100 is placed in the placing cavity 11. The bottle cap 2 is provided with an opening 21. The sealing member 5 is installed at the opening 21 and forms a containing cavity 22 together with the bottle cap 2. The containing cavity 22 is placed with a reconstitution buffer. The pressing member 3 is installed on the bottle cap 2. The piercing member 4 is arranged in the containing cavity 22 and connected with the pressing member 3.

[0039] In the present embodiment, the pressing member 3 drives the piercing member 4 to move towards the sealing member 5, and the bottle cap 2 drives the pressing member 3 and the piercing member 4 to rotate. The piercing member 4 cuts the sealing member 5, so that the reconstitution buffer flows from the opening 21 into the placing cavity 11 through the bottle mouth 12.

[0040] It can be understood that the bottle body 1 and the bottle cap 2 of the dry and wet separation reagent bottle are rotatably connected, so that the bottle body 1 and the bottle cap 2 can rotate relative to each other. The bottle body 1 is provided with a placing cavity 11 and a bottle mouth 12 in communication with the placing cavity 11. The freeze-dried powder 100 is placed in the placing cavity 11. The bottle cap 2 is provided with an opening 21. The sealing member 5 is installed at the opening 21 and forms a containing cavity 22 together with the bottle cap 2. The containing cavity 22 is placed with a reconstitution buffer. The pressing member 3 is installed on the bottle cap 2. The piercing member 4 is arranged in the containing cavity 22 and connected with the pressing member 3. The pressing member 3 drives the piercing member 4 to move towards the sealing member 5, and the bottle cap 2 drives the pressing member 3 and the piercing member 4 to rotate. The piercing member 4 cuts the sealing member 5, so that the reconstitution buffer flows from the opening 21 into the placing cavity 11 through the bottle mouth 12. The reconstitution buffer is mixed with the freeze-dried powder 100. By driving the piercing member 4 to move and the bottle cap 2 to rotate the piercing member 4, the sealing member 5 can be cut, so that the freeze-dried powder 100 can be reconstituted by one press and one rotation. The operation is simple, the human operation error is solved, and the work efficiency is improved.

[0041] In addition, since the reconstitution buffer is directly installed in the bottle cap 2, it is not necessary to use a pipette to adsorb the reconstitution buffer, which can reduce the experimental instruments used in the existing reconstitution method, thereby reducing the burden of soaking and cleaning.

[0042] It should be noted that the pressing member 3 can be provided with an anti-misoperation assembly. In this way, the pressing member 3 will not move the piercing member 4 due to misoperation, thereby avoiding the closure 5 from being scratched. Specifically, the anti-misoperation assembly can be a locking member, which is installed on the bottle cap 2 and penetrates through the pressing member 3.

[0043] It should be noted that the connection between the pressing member 3 and the bottle cap 2 is provided with a sealing member. In this way, the reconstitution buffer will not leak from the connection between the pressing member 3 and the bottle cap 2.

[0044] Further, the pressing member 3 is installed at the edge of the bottle cap 2. When the piercing member 4 is connected to the pressing member 3, the piercing member 4 is arranged close to the cavity wall of the accommodating cavity 22, so that during the pressing process, the pressing member 3 drives the piercing member 4 to move towards the edge of the closure 5, and during the rotation of the bottle cap 2, the bottle cap 2 drives the pressing member 3 and the piercing member 4 to scratch along the edge of the closure 5, so that the reconstitution buffer can flow into the placement cavity 11 from the bottle opening 12 through the opening 21. Since the piercing member 4 scratches along the edge of the closure 5, the reconstitution buffer will not be left on the closure 5, thereby enabling precise metering of the reconstitution buffer.

[0045] Further, the pressing member 3 is a structure made of elastic rubber. Since the pressing member 3 is a structure made of elastic rubber, the pressing member 3 can be pressed towards the closure 5, so that the pressing member 3 can drive the piercing member 4 to move towards the closure 5, and after the external force on the pressing member 3 is removed, the pressing member 3 restores to the original position by its own elasticity, so that the pressing member 3 drives the piercing member 4 to restore to the original position.

[0046] Of course, in other embodiments, the bottle cap 2 includes a cap body and a cap cover, the cap cover is connected to the cap body and connected to the pressing member 3, and the cap cover is a structure made of elastic rubber. During the pressing process of the pressing member 3, the pressing member 3 drives the cap cover to elastically deform, the pressing member 3 drives the piercing member 4 to move towards the closure 5, and after the external force on the pressing member 3 is removed, the elastic deformation of the cap cover is restored, and the cap cover drives the pressing member 3 and the piercing member 4 to restore to the original position.

[0047] Further, the pressing member 3 protrudes from the bottle cap 2. Since the pressing member 3 protrudes from the bottle cap 2, the pressing member 3 can be more easily pressed, so that the piercing member 4 can smoothly move towards the closure 5 under the driving of the pressing member 3.

[0048] Specifically, the surface of the pressing member 3 has an anti-slip pattern. In this way, the friction between the pressing member 3 and the pressing member 3 can be increased. In implementation, the anti-slip pattern can be a groove or a protrusion.

[0049] In an embodiment, as shown in FIG. 1, the bottle cap 2 includes a cap body and a cap cover, the cap cover is connected to the cap body and connected to the pressing member 3, and the cap cover is a structure made of elastic rubber. Figure 1As shown, the piercing member 4 is arranged at an angle with the pressing member 3. In this way, the piercing member 4 can be closer to the edge of the accommodating cavity 22, so that the piercing member 4 avoids leaving too much of the closure 5 on the cavity wall of the accommodating cavity 22 during the process of breaking the closure 5. In some embodiments, the piercing member 4 is arranged at an angle of 20 degrees, 30 degrees, 40 degrees, 50 degrees or 60 degrees with the pressing member 3. In practice, the piercing member 4 can be close to the cavity wall of the accommodating cavity 22, and the angle between the piercing member 4 and the pressing member 3 is not specifically limited.

[0050] In the present embodiment, the piercing member 4 comprises an extension 41 and a piercing portion 42 connected to the extension 41, and the piercing portion 42 is provided with an inclined surface 421. By providing the inclined surface 421, the piercing portion 42 can more easily break the closure 5, so that the reconstitution buffer solution can smoothly flow into the placement cavity 11.

[0051] Further, the plane of the inclined surface 421 is perpendicular to the closure 5. In this way, the piercing portion 42 can more easily break the closure 5.

[0052] In an embodiment, as shown in Figure 1 As shown, the bottle body 1 is provided with external threads or internal threads, and the bottle cap 2 is provided with external threads or internal threads, and the bottle body 1 and the bottle cap 2 are threadedly connected. In this way, the bottle cap 2 and the bottle body 1 can be relatively rotated, so that the bottle cap 2 can drive the piercing member 4 to rotate, so that the piercing member 4 breaks the closure 5. Since the bottle cap 2 and the bottle body 1 are threadedly connected, the bottle cap 2 and the bottle body 1 can be disassembled, so that the freeze-dried reconstitution solution in the bottle body 1 can be poured out.

[0053] In an embodiment, as shown in Figure 1 As shown, the piercing member 4 is a structural member made of plastic material. In this way, the overall weight of the bottle cap 2 can be reduced, and the manufacturing cost can be saved.

[0054] The utility model further provides an analyzer, the analyzer includes reagent rack, analysis module, transfer module and the reagent bottle of any one embodiment of dry and wet separation, the reagent bottle is placed on the reagent rack, and the transfer module is used for transferring the reagent rack to the analysis module, and the analysis module is used for analyzing the reagent in the reagent bottle.

[0055] In the embodiment, it can be understood that the dry-wet separation reagent bottle is used, the bottle body 1 and the bottle cap 2 of the dry-wet separation reagent bottle are rotationally connected, the bottle body 1 and the bottle cap 2 can relatively rotate, the bottle body 1 is provided with a placing cavity 11 and a bottle mouth 12 communicated with the placing cavity 11, the freeze-dried powder 100 is placed in the placing cavity 11, the bottle cap 2 is provided with an opening 21, the sealing element 5 is installed at the opening 21 and forms a containing cavity 22 with the bottle cap 2, the containing cavity 22 is placed with the reconstitution buffer, the pressing element 3 is installed on the bottle cap 2, the piercing element 4 is arranged in the containing cavity 22 and connected with the pressing element 3, the pressing element 3 is pressed to drive the piercing element 4 to move to the direction of the sealing element 5, and the bottle cap 2 is rotated to drive the pressing element 3 and the piercing element 4 to rotate, the piercing element 4 cuts the sealing element 5, so that the reconstitution buffer flows into the placing cavity 11 from the opening 21 through the bottle mouth 12, the reconstitution buffer is mixed with the freeze-dried powder 100, the pressing element 3 is arranged to drive the piercing element 4 to move, and the bottle cap 2 drives the piercing element 4 to rotate, so that the sealing element 5 can be cut, the freeze-dried powder 100 can be reconstituted by one pressing and one rotating, the operation is simple, the manual operation error is solved, and the work efficiency is improved.

[0056] In addition, since the reconstitution buffer is directly arranged in the bottle cap 2, the reconstitution buffer does not need to be adsorbed by using a suction tube, the experimental instruments used in the existing reconstitution mode can be reduced, and the soaking and cleaning burden is reduced.

[0057] The technical features of the above-described embodiments can be combined arbitrarily, and in order to make the description simple, all possible combinations of the technical features in the above-described embodiments are not described, however, as long as the combination of the technical features does not exist contradictory, it should be considered that the combination is within the scope of the present application.

[0058] The above disclosure is only the preferred embodiment of the present application, and of course cannot limit the scope of the present application, therefore, the equivalent changes made according to the present application claims still belong to the scope of the present application.

Claims

1. A desiccated reagent bottle characterized in that, The dry-wet separation reagent bottle comprises: a bottle body provided with a placing cavity and a bottle mouth connected with the placing cavity, and a freeze-dried powder is placed in the placing cavity; a bottle cap provided with an opening and rotationally connected with the bottle body; a pressing member installed on the bottle cap; a closure installed at the opening and surrounding the bottle cap to form a containing cavity, and a reconstitution buffer is placed in the containing cavity; a piercing member arranged in the containing cavity and connected with the pressing member; pressing the pressing member to drive the piercing member to move towards the closure, and rotating the bottle cap to drive the pressing member and the piercing member to rotate, the piercing member cuts the closure to allow the reconstitution buffer to flow from the opening into the placing cavity through the bottle mouth.

2. The drier-wetter separated reagent bottle of claim 1, wherein, The pressing member is installed at the edge of the bottle cap.

3. The drier-wetter separated reagent bottle of claim 2, wherein, The pressing member is a structural member made of elastic rubber.

4. The drier-wetter separated reagent bottle of claim 2, wherein, The pressing member protrudes from the bottle cap.

5. The drier-wetter separated reagent bottle of claim 2, wherein, The piercing member is arranged at an angle with the pressing member.

6. The drier-wetter separated reagent bottle of claim 5, wherein, The piercing member comprises an extension and a piercing part connected with the extension, and the piercing part is provided with an inclined surface.

7. The drier-wetter separated reagent bottle of claim 6, wherein, The plane of the inclined surface is perpendicular to the closure.

8. The drier-wetter separated reagent bottle of claim 1, wherein, The bottle body is provided with external threads or internal threads, the bottle cap is provided with external threads or internal threads, and the bottle body and the bottle cap are threadedly connected.

9. The drier-wetter separated reagent bottle of claim 1, wherein, The piercing member is a structural member made of plastic.

10. An analyzer characterized by, The analyzer comprises a reagent rack, an analysis module, a transfer module and the dry-wet separation reagent bottle according to any one of claims 1-9, the reagent bottle is placed on the reagent rack, the transfer module is used to transfer the reagent rack to the analysis module, and the analysis module is used to analyze the reagent in the reagent bottle.