Treatment device for pathological cell wax blocks

The pathological cell wax block processing device, which integrates metal bath and centrifugal functions on the same device, solves the problem of low efficiency in pathological cell wax block processing and achieves efficient reagent melting and cell enrichment.

CN223470860UActive Publication Date: 2025-10-24HAOMING MEDICAL SUPPLY CHAIN MANAGEMENT (GUANGDONG) CO LTD
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Patent Information

Application Number
CN202422874447.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-25
Publication Date
2025-10-24
Estimated Expiration
2034-11-25

AI Technical Summary

Technical Problem

In the prior art, the processing of pathological cell wax blocks needs to be carried out separately on a metal bath device and a centrifugal device, resulting in low experimental efficiency.

Method used

A processing device is designed, which includes a chassis and a tube rack. The chassis is equipped with two chambers: a metal bath and a centrifuge. The tube rack is used to achieve reagent melting and cell enrichment on the same machine. The tube rack can be transferred between different chambers and used in combination with the metal bath and centrifuge mechanism.

Benefits of technology

Reagent melting and cell enrichment are completed on the same device, which improves the experimental efficiency of pathological cell wax block preparation and reduces experimental costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a processing device for pathological cell wax blocks, which comprises a case and a tube carrying frame, a first cavity for accommodating a metal bath mechanism and a second cavity for accommodating a centrifugal mechanism are formed in the case, and a first cavity opening communicated with the first cavity and a second cavity opening communicated with the second cavity are formed in the case; the pipe carrying frame is arranged in the first cavity through the first cavity opening and connected with the metal bath mechanism in a heat conduction mode to complete metal bath, and then is arranged in the second cavity through the second cavity opening and connected with the centrifugal mechanism. According to the utility model, reagent melting and cell enrichment and cell tiling integration blocks can be realized on the same machine, so that pathological cell wax blocks are convenient to manufacture, and the experiment efficiency is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to biological tissue cell pretreatment equipment's technical field, in particular to a kind of processing device for pathological cell wax block. BACKGROUND

[0002] In the pathology department, biological tissue cells are often needed to be experimented, and corresponding pathological data is obtained;In order to meet the needs of long-term preservation, biological tissue cells are generally made into wax blocks;When experiment is needed, cell wax block needs to be melted in metal bath equipment, and after melting, it is transferred to centrifugal equipment to complete cell enrichment. Since the above two biological tissue cell processing processes are completed by different equipment, the experimental efficiency is obviously reduced. UTILITY MODEL CONTENT

[0003] The utility model discloses a kind of processing device for pathological cell wax block, which can realize reagent melting, cell enrichment cell flatly laid enrichment block on the same machine, facilitate pathological cell wax block manufacturing, improve experimental efficiency.

[0004] The utility model discloses a kind of processing device for pathological cell wax block, which can realize reagent melting, cell enrichment cell flatly laid enrichment block on the same machine, facilitate pathological cell wax block manufacturing, improve experimental efficiency.

[0005] A kind of processing device for pathological cell wax block, including cabinet and carrier tube frame, the first chamber that the cabinet interior forms and contains metal bath mechanism, and the second chamber that contains centrifugal mechanism, first cavity mouth that is connected with the first chamber is provided on the cabinet, and second cavity mouth that is connected with second chamber;The carrier tube frame is placed in the first chamber by the first cavity mouth and is connected with the metal bath mechanism to complete metal bath by heat conduction, and is connected with the centrifugal mechanism by the second cavity mouth and is placed in the second chamber.

[0006] Based on the above technical scheme, the utility model can be improved as follows:

[0007] Further, the top of the carrier tube frame is provided with flanges on opposite sides, and the top plate of the cabinet is provided with a stepped groove at the first cavity mouth. The flanges on the carrier tube frame cooperate with the stepped groove of the first cavity mouth to enable the carrier tube frame to be installed in the first chamber.

[0008] Further, the carrier tube frame is provided with multiple pieces, and the multiple pieces of carrier tube frame are installed side by side in the first chamber.

[0009] Further, the first cavity mouth is provided with a pressing plate at the stepped groove, and the pressing plate abuts against the top surface of the carrier tube frame to limit the carrier tube frame in the first chamber.

[0010] Further, the centrifugal mechanism comprises a hanger capable of rotating around an axis, and a driving member for driving the hanger to rotate; the hanger is provided with at least two hanging positions, and the carrier tube frame is hung at the hanging positions of the hanger.

[0011] Further, the hanger comprises a hanger body and hanging parts extending from the hanger body, and the end of each hanging part is a hanging position and forms a hanging groove, and the carrier tube frame is swingably hung in the hanging groove through a hooking structure.

[0012] Further, the hooking structure comprises hooks arranged on two opposite inner groove walls of the hanging groove, and guide grooves arranged on the outer side of the flange of the carrier tube frame, and the carrier tube frame is moved along a preset movement track relative to the hanger to complete the hanging through cooperation of the guide grooves and the hooks.

[0013] Further, the guide groove is a vertical straight groove, the bottom end of the guide groove is communicated with the bottom side of the flange and forms a guide inlet, and the top end of the guide groove is closed; the hook enters the guide groove through the guide inlet and slides along the guide groove to the top end groove wall of the guide groove to complete the hanging.

[0014] Further, the metal bath mechanism comprises a heating member for heating the carrier tube frame, and the heating member is fixedly installed in the first cavity and is in close contact with the carrier tube frame.

[0015] Further, the case is provided with openable and closable first and second case covers at the top, respectively; the first case cover is arranged at the top first cavity opening of the case, and the second case cover is arranged at the top second cavity opening of the case.

[0016] Compared with the prior art, the present application has the following advantages:

[0017] The case and the carrier tube frame are provided, two cavities are formed in the case to accommodate the metal bath mechanism and the centrifugal mechanism, respectively, two cavity openings are arranged on the case to communicate with the two cavities, respectively, the carrier tube frame is in heat-conducting connection with the metal bath mechanism in one of the cavities to complete the metal bath, and the carrier tube frame is connected with the centrifugal mechanism in the other cavity to complete the centrifugation, so that the reagent melting and the cell flatly enriched into a block can be realized on the same machine, the pathological cell wax block manufacturing is facilitated, and the experimental efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS

[0018] The present application will be further described in detail below in combination with the drawings and specific embodiments

[0019] Fig. 1 It is a structure schematic view of the processing device for the pathological cell wax block in the embodiments;

[0020] Fig. 2Structure schematic diagram of the tube carrier in the embodiment;

[0021] Fig. 3 Structure schematic diagram of the inside of the first chamber of the cabinet in the embodiment;

[0022] Fig. 4 Structure schematic diagram of the hanger in the embodiment.

[0023] Reference signs on the drawing: 1-cabinet, 2-baffle, 3-first chamber, 4-second chamber, 5-first chamber opening, 6-second chamber opening, 7-first cabinet cover, 8-second cabinet cover, 9-tube carrier, 10-jack, 11-flange, 12-step groove, 13-pressing plate, 14-electric heating plate, 15-hanger, 15a-hanger body, 15b-hanging part, 16-hanging groove, 17-hook, 17a-connection part, 17b-hook part, 18-guide groove, 19-motor, 20-isolation cover. DETAILED DESCRIPTION

[0024] The specific embodiments of the utility model will be further described below in combination with the drawings. The description of these embodiments is used to help understand the utility model, but does not constitute the limitation of the utility model. In addition, the technical features involved in each embodiment of the utility model described below can be combined with each other as long as they do not conflict with each other.

[0025] Reference Figs. 1 to 4 , the embodiment relates to a kind of processing device for pathological cell wax block, including cabinet 1, and metal bath mechanism and centrifugal mechanism are arranged in cabinet 1, metal bath mechanism is used to melt cell wax block, centrifugal mechanism is used to centrifugal enrichment cell.

[0026] Cabinet 1 is rectangular box structure, cabinet 1 includes mutually spliced panel, back plate, top plate, bottom plate and two side plates;Baffle 2 is arranged in cabinet 1, baffle 2 divides the first chamber 3 and the second chamber 4 into the space in cabinet 1, first chamber 3 is accommodated metal bath mechanism, and centrifugal mechanism is accommodated in the second chamber 4;First chamber opening 5 corresponding to first chamber 3 is respectively provided with first chamber opening 5 and second chamber opening 6 corresponding to second chamber 4 on the top plate of cabinet 1;The test tube loaded with to-be-melted cell wax block is placed in first chamber 3 from first chamber opening 5 by heat-conducting tube carrier 9 to carry out metal bath to melt reagent, and the test tube after completing metal bath is taken out from first chamber opening 5 and is placed in second chamber 4 from second chamber opening 6 to carry out centrifugal to enrich cell, so as to realize reagent melting and cell flat laying enrichment block on the same machine, improve experimental efficiency.

[0027] The cabinet 1 is provided with a first box cover 7 and a second box cover 8 at the top, respectively; the first box cover 7 is arranged at the first cavity opening 5 of the top of the cabinet 1 to seal the first chamber 3 when the reagent is melted; the second box cover 8 is arranged at the second cavity opening 6 of the top of the cabinet 1 to seal the second chamber 4 when the cells are enriched by centrifugation; since the two chambers are independent of each other and do not interfere with each other, the reagent melting and cell spreading enrichment can be carried out at the same time.

[0028] The metal bath mechanism includes a heating element for heating the carrier tube frame 9, which is detachably installed in the first chamber 3 through the first cavity opening 5, and the heating element is fixedly installed in the first chamber 3 and is in close contact with the carrier tube frame 9. The heat generated by the heating element is conducted to the test tube through the carrier tube frame 9 to melt the reagent.

[0029] The carrier tube frame 9 in this embodiment is a rectangular block made of aluminum, and other heat-conducting materials such as copper can also be used instead according to actual conditions; the carrier tube frame 9 is provided with a jack 10 for inserting the test tube; the top of the carrier tube frame 9 is provided with flanges 11 on opposite sides; the top plate of the cabinet 1 is provided with a rectangular stepped groove 12 at the first cavity opening 5, which cooperates with the flanges 11 on the carrier tube frame 9 and the stepped groove 12 of the first cavity opening 5 to enable the carrier tube frame 9 to be installed in the first chamber 3.

[0030] The jacks 10 on the carrier tube frame 9 can be provided in multiple numbers to facilitate loading of multiple test tubes and simultaneous melting of multiple reagents.

[0031] The carrier tube frame 9 can be provided in multiple pieces, and the multiple carrier tube frames 9 are installed side by side in the first chamber 3.

[0032] The first cavity opening 5 is provided with a pressing plate 13 at the stepped groove 12, which abuts against the top surface of the carrier tube frame 9 to limit the carrier tube frame 9 in the first chamber 3; when the pressing plate 13 abuts against the carrier tube frame 9, the top surface of the pressing plate 13 is flush with the top surface of the top plate of the cabinet 1; when the first box cover 7 is closed, the bottom surface of the first box cover 7 abuts against the top plate and the pressing plate 13 of the cabinet 1.

[0033] The heating element in this embodiment is an electric heating plate 14 in the prior art, which is fixedly arranged in the first chamber 3 through a support frame and is in close contact with the bottom surface of the carrier tube frame 9. The heat generated by the electric heating plate 14 is conducted from the bottom to the top of the carrier tube frame 9 to complete the melting of the reagent.

[0034] In order to improve the melting efficiency, the electric heating plate 14 can also be provided in multiple numbers, which are in close contact with the outer peripheral surface of the carrier tube frame 9, and the heat generated by the electric heating plate 14 is conducted from the outer peripheral side to the center of the carrier tube frame 9.

[0035] The centrifugal mechanism comprises a hanger 15 rotatable around an axis and a driving member for driving the hanger 15 to rotate; the hanger 15 is provided with at least two hanging positions, and the loaded tube rack 9 after the metal bath can be hung at the hanging positions of the hanger 15, and the driving member drives the hanger 15 to rotate to form a centrifugal force to carry out cell enrichment.

[0036] In the embodiment, the hanger 15 is a cross-shaped frame structure, which comprises a hanger body 15a and hanging parts 15b extending from the hanger body 15a to all directions, the end of each hanging part 15b serves as a hanging position and forms a hanging groove 16, and the loaded tube rack 9 is swingably hung in the hanging groove 16 of the hanger 15 through a hook structure.

[0037] The hanging groove 16 is a U-shaped groove body, the hook structure comprises hooks 17 arranged on two opposite inner groove walls of the hanging groove 16 and guide grooves 18 arranged on the outer side of the flange 11 of the loaded tube rack 9, the loaded tube rack 9 moves along a preset movement track relative to the hanger 15 to complete the hanging through cooperation of the guide grooves 18 and the hooks 17; the guide groove 18 is a vertical linear groove body, the bottom end of the guide groove 18 is connected to the bottom side of the flange 11 and forms a guide inlet, and the top end of the guide groove 18 is closed; the hook 17 enters the guide groove 18 through the guide inlet and slides along the guide groove 18 to abut against the top end groove wall of the guide groove 18, thereby completing the hanging of the loaded tube rack 9.

[0038] The hook 17 comprises a connecting part 17a and a hook part 17b at the free end of the connecting part 17a, the connecting part 17a is arranged on the groove side wall surface of the guide groove 18, and the connecting part 17a and the hook part 17b are both columnar structures, wherein the diameter of the hook part 17b is greater than the diameter of the connecting part 17a, and the diameter and thickness of the hook part 17b are opposite to the width and depth of the guide groove 18, so that when the hook part 17b of the hook 17 abuts against the top end groove wall of the guide groove 18, the loaded tube rack 9 can swing around the axis of the hook 17 relative to the hanger 15 under the action of the centrifugal force generated when the hanger 15 rotates, thereby realizing cell enrichment; in the embodiment, the loaded tube rack 9 with the above structure can be used for reagent melting and cell spreading and enrichment into a block, and a hanger for loading test tubes is not required to be additionally and separately configured, the test tubes can be transferred from the first chamber 3 to the second chamber 4 for cell enrichment after reagent melting, the experimental efficiency can be improved, and the experimental cost can be reduced.

[0039] In the embodiment, the driving member is an electric motor 19 in the prior art, the electric motor 19 is fixedly installed in the cabinet 1, the rotating shaft of the electric motor 19 is connected with the hanger body 15a of the hanger 15, and when the electric motor 19 is started, the rotating shaft of the electric motor 19 rotates to drive the hanger 15 to rotate to form a centrifugal force.

[0040] In the second chamber 4 is further provided with the isolation cover 20, the top of isolation cover 20 is open and is connected with the second chamber 6, the bottom of isolation cover 20 is closed, the hanger 15 is located in the isolation cover, the motor 19 is located outside the isolation cover 20, the rotating shaft of motor 19 extends vertically upward, passes through the bottom of isolation cover 20 and enters the isolation cover to be connected with the hanger main body 15a of hanger 15;The isolation cover 20 is used to block the liquid accidentally splashed from the test tube nozzle to fall in the second chamber 4, so as to avoid the short circuit fault of motor 19, and facilitate cleaning.

[0041] The above embodiments of the utility model are not the limitation of the protection scope of the utility model, the implementation mode of the utility model is not limited to this, and other various forms of modification, replacement or change of the above structure of the utility model are made according to the ordinary technical knowledge and conventional means in the art under the premise of not departing from the above basic technical thought of the utility model, which should be within the protection scope of the utility model.

Claims

1. A processing device for pathological cell wax blocks, characterized in that, The metal bath device comprises a cabinet and a carrier tube frame, the cabinet is internally formed with a first chamber for accommodating a metal bath mechanism and a second chamber for accommodating a centrifugal mechanism, the cabinet is provided with a first chamber opening communicating with the first chamber and a second chamber opening communicating with the second chamber; the carrier tube frame is placed in the first chamber through the first chamber opening to be in thermal connection with the metal bath mechanism after the metal bath is completed, and is placed in the second chamber through the second chamber opening to be connected with the centrifugal mechanism.

2. The apparatus for processing of pathological cell wax blocks according to claim 1, characterized in that, The top of the carrier tube frame is provided with flanges on opposite sides, and the top plate of the cabinet is provided with stepped grooves at the first chamber opening, the flanges on the carrier tube frame are matched with the stepped grooves of the first chamber opening to enable the carrier tube frame to be installed in the first chamber.

3. The apparatus for processing of pathological cell wax blocks according to claim 2, characterized in that, The carrier tube frame is provided with multiple pieces, and the multiple pieces of carrier tube frames are installed side by side in the first chamber.

4. The apparatus for processing of pathological cell wax blocks according to claim 2, characterized in that, The first chamber opening is provided with a pressing plate at the stepped groove, the pressing plate abuts against the top surface of the carrier tube frame to limit the carrier tube frame in the first chamber.

5. The apparatus for processing of pathological cell wax blocks according to claim 2, characterized in that, The centrifugal mechanism comprises a hanger capable of rotating around an axis and a driving member for driving the hanger to rotate, and the hanger is provided with at least two hanging positions, and the carrier tube frame is hung at the hanging position on the hanger.

6. The device for processing pathological cell wax blocks according to claim 5, characterized in that, The hanger comprises a hanger body and a hanging part extending from the hanger body in all directions, the end of each hanging part serves as a hanging position and forms a hanging groove, and the carrier tube frame is swingably hung in the hanging groove through a hooking structure.

7. The device for processing pathological cell wax blocks according to claim 6, characterized in that, The hooking structure comprises a hook provided on two opposite inner groove walls of the hanging groove and a guide groove provided on the outer side surface of the flange of the carrier tube frame, the guide groove and the hook are matched to enable the carrier tube frame to move along a preset movement track relative to the hanger to complete the hanging.

8. The device for processing pathological cell wax blocks according to claim 7, characterized in that, The guide groove is a vertical linear groove body, the bottom end of the guide groove communicates with the bottom side of the flange and forms a guide inlet, and the top end of the guide groove is closed; the hook enters the guide groove through the guide inlet and slides along the guide groove to abut against the top end groove wall of the guide groove to complete the hanging.

9. The device for processing pathological cell wax blocks according to any one of claims 1-8, characterized in that, The metal bath mechanism comprises a heating member for heating the carrier tube frame, and the heating member is fixedly installed in the first chamber and is in close contact with the carrier tube frame.

10. The device for processing pathological cell wax blocks according to claims 1-8, characterized in that, The cabinet is respectively provided with a first cabinet cover and a second cabinet cover which can be opened and closed at the top; the first cabinet cover is arranged at the top of the cabinet at the first chamber opening, and the second cabinet cover is arranged at the top of the cabinet at the second chamber opening.