Photodynamic balloon catheter

Abstract

The utility model relates to the technical field of medical apparatus and instruments, in particular to a photodynamic balloon catheter which comprises a catheter body, a balloon sleeve and a balloon sleeve. The optical fibers are arranged in the containing space, the optical fibers surround a circle to form a hollow annular structure, the annular structure is used for forming a guide wire containing structure, and the interior of the annular structure is suitable for the guide wire to penetrate through. The annular structure is arranged in the catheter body to replace a guide wire catheter for guiding the guide wire in the prior art, the structure of the photodynamic balloon catheter is simplified, the production cost is reduced, illumination borne by the surface of the balloon is more uniform, the annular structure is used for replacing a single optical fiber in the prior art, and therefore the light emitting efficiency is improved. The optical power of each optical fiber is reduced, the requirement for the quality of the optical fibers is reduced, the production cost of the photodynamic balloon catheter is reduced, or under the condition that the power of each optical fiber is not changed, the total power is greatly improved, and then the treatment effect is improved.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a photodynamic balloon catheter. Background Technology

[0002] Percutaneous interventional therapy has become one of the commonly used treatment techniques worldwide. For endovascular stenosis, balloon dilation or stent implantation is usually used for treatment. However, both methods have their own shortcomings: after balloon dilation, the endothelium of the dilated arterial segment is damaged and elastic fibers are broken, leading to thrombosis and intimal hyperplasia; the balloon has a short inflation time during use and lacks long-term support, resulting in elastic recoil and remodeling of the vessel wall; and long-term placement of vascular stents can also cause proliferative reactions in the body as foreign bodies, leading to in-stent restenosis.

[0003] To address the aforementioned technical challenges, a new vascular treatment technology has emerged in recent years: Natural Vascular Scaffolding (NVS). This technology involves coating a small-molecule compound onto the surface of a balloon. After the balloon is delivered to the target location in the blood vessel, it expands, spreading the small-molecule compound to the vascular proteins. A specific wavelength of light emitted from an optical fiber activates the small molecules, causing them to bind to the vascular proteins and provide support for the blood vessel.

[0004] Existing photodynamic balloon catheters employ natural vascular stent technology, with a balloon connected to one end of the catheter body, an inner tube inside the catheter containing a guidewire, and an optical fiber placed between the inner tube and the catheter wall, making the overall structure of the photodynamic balloon catheter relatively complex. Utility Model Content

[0005] In view of this, the present invention provides a photodynamic balloon catheter to solve the problem of the complex overall structure of the photodynamic balloon catheter.

[0006] This utility model provides a photodynamic balloon catheter, comprising:

[0007] The catheter body has a receiving space inside it;

[0008] Multiple optical fibers are disposed within the accommodating space, and the multiple optical fibers are arranged in a hollow ring structure. The ring structure is used to form the accommodating structure for the guide wire, and the guide wire is suitable for passing through the ring structure.

[0009] Beneficial effects: By arranging multiple optical fibers around the catheter body to form a hollow ring structure, the ring structure replaces the guidewire catheter used in the prior art, simplifying the structure of the photodynamic balloon catheter and reducing production costs. At the same time, the multiple optical fibers make the light received on the balloon surface more uniform. Furthermore, replacing the single optical fiber in the prior art with multiple optical fibers reduces the optical power of each optical fiber, lowering the requirements for fiber quality, thereby reducing the production cost of the photodynamic balloon catheter. Alternatively, while keeping the power of each optical fiber unchanged, the total power can be greatly increased, thereby improving the treatment effect.

[0010] In one alternative embodiment, the plurality of optical fibers are fixed together by adhesive bonding.

[0011] Beneficial effects: By bonding and fixing multiple optical fibers together, it is easy to form a stable ring structure to accommodate the guide wire. The structure is relatively simple and makes the illumination more stable.

[0012] In one alternative embodiment, the optical fiber has a circular cross-section and a diameter of 0.1 mm to 1 mm.

[0013] Beneficial effects: The smaller the diameter of the optical fiber, the better the effect. Considering strength, flexibility, light distribution, and production cost, optical fibers with a diameter between 0.1mm and 1mm are more suitable.

[0014] In one alternative embodiment, the photodynamic balloon catheter includes:

[0015] A catheter seat is connected to the proximal end of the catheter body. The catheter seat has a hollow structure and a first outlet is provided on the catheter seat. The hollow cavity of the annular structure is connected to the first outlet (301). The guide wire is connected to the outside through the first outlet (301). One end of the optical fiber is used to connect to an external laser generator through the first outlet.

[0016] Beneficial effects: By connecting both the guidewire and the optical fiber to the outside through the first outlet, an outlet structure is reduced, thus lowering production costs. At the same time, this design eliminates the need for an opening on the annular structure for the guidewire to enter, simplifying the annular structure. The guidewire also does not need to bend when entering the annular structure, resulting in smoother conduction of the guidewire.

[0017] In one optional embodiment, the catheter hub is provided with a balloon inflation port;

[0018] The photodynamic balloon catheter includes a balloon connected to the distal end of the catheter body;

[0019] A balloon inflation cavity is formed between the catheter body and the annular structure. One end of the balloon inflation cavity is connected to the balloon inflation interface, and the other end is connected to the balloon.

[0020] Beneficial effects: The balloon inflation cavity formed by the annular structure and the catheter body allows for the inflation and deflation of the balloon, causing it to expand or contract, which simplifies the structure of the catheter body and reduces the production cost of the photodynamic balloon catheter.

[0021] In one alternative embodiment, the annular structure is covered with a thin film, and the balloon filling cavity is formed between the catheter body and the thin film.

[0022] Beneficial effects: The film is used to protect the annular structure, thereby improving the strength of the annular structure and increasing the service life of the photodynamic balloon catheter.

[0023] In one alternative embodiment, the annular structure is fixedly connected to the thin film.

[0024] Beneficial effects: The fixed connection between the ring structure and the film further enhances the strength of the ring structure and improves its service life.

[0025] In one alternative embodiment, the outer surface of the balloon is coated with a vascular repair coating, the vascular repair coating comprising a vascular repair material.

[0026] Beneficial effects: The vascular repair coating is suitable for inducing cross-linking of proteins in the blood vessel wall, forming a natural vascular scaffold, which enables the dilated blood vessels to be maintained.

[0027] In one alternative embodiment, the outer surface of the balloon is provided with a restenosis-inhibiting drug coating, which is used to treat vascular stenosis and occlusion. Attached Figure Description

[0028] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0029] Figure 1 This is a partially cross-sectional structural diagram of one embodiment of the photodynamic balloon catheter of this utility model;

[0030] Figure 2 for Figure 1 The front view of the embodiment shown;

[0031] Figure 3 for Figure 1 Side view of the embodiment shown;

[0032] Figure 4 for Figure 2 Sectional view of BB;

[0033] Figure 5 for Figure 3 Sectional view of AA;

[0034] Figure 6 for Figure 1 The enlarged view of part I shown;

[0035] Explanation of reference numerals in the attached figures:

[0036] 1. Balloon; 2. Catheter body; 3. Catheter hub; 301. First outlet; 302. Balloon inflation interface; 4. Optical fiber; 5. Membrane; 6. Balloon inflation cavity. Detailed Implementation

[0037] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0038] The following is combined Figures 1 to 6 The following describes embodiments of the present invention.

[0039] According to an embodiment of the present invention, a photodynamic balloon catheter is provided, comprising: a catheter body 2, wherein the catheter body 2 has an accommodating space; a plurality of optical fibers 4, disposed within the accommodating space, wherein the plurality of optical fibers 4 surround a hollow annular structure, the annular structure being used to constitute an accommodating structure for a guidewire, and the annular structure being suitable for the guidewire to pass through.

[0040] By setting multiple optical fibers 4 around the catheter body 2, forming a hollow ring structure, the ring structure replaces the guidewire catheter in the prior art, simplifying the structure of the photodynamic balloon catheter and reducing production costs. At the same time, the multiple optical fibers 4 make the light received on the surface of the balloon 1 more uniform. In addition, replacing the single optical fiber 4 in the prior art with multiple optical fibers 4 reduces the optical power of each optical fiber 4 and reduces the requirements for the quality of the optical fiber 4, thereby reducing the production cost of the photodynamic balloon catheter. Alternatively, while keeping the power of each optical fiber 4 unchanged, the total power can be greatly increased, thereby improving the treatment effect.

[0041] like Figures 4-6 As shown, in this embodiment, optical fiber 4 is a low-power optical fiber with a circular cross-section and a diameter of 0.1mm-1mm. Multiple optical fibers 4 arranged in a circle provide a more uniform light distribution. As a possible alternative implementation, optical fiber 4 can also be a high-power optical fiber. As another possible implementation, optical fiber 4 can be a silica optical fiber or a plastic optical fiber; the material of optical fiber 4 is not strictly limited here.

[0042] The smaller the diameter of fiber 4, the better the effect. Considering strength, flexibility, light distribution effect and production cost, fiber 4 with a diameter between 0.1mm and 1mm is more suitable. This embodiment only provides a relatively suitable diameter range. In other embodiments, the diameter of fiber 4 can also be set to other numerical ranges. Here, we do not impose too many restrictions on the diameter of fiber 4.

[0043] In this embodiment, optical fiber 4 is suitable for conducting light with a wavelength of 400nm-500nm. In other embodiments, optical fiber 4 can also conduct light of other wavelengths; no further limitations are imposed here.

[0044] In this embodiment, multiple optical fibers 4 are fixed together by bonding, which facilitates the formation of a stable ring structure for accommodating the guide wire. The structure is relatively simple and at the same time, it makes the illumination more stable.

[0045] In this embodiment, the catheter seat 3 is connected to the proximal end of the catheter body 2. The catheter seat 3 is a hollow structure and has a first outlet 301. The annular hollow cavity is connected to the first outlet 301. The guide wire is connected to the outside through the first outlet 301. One end of the optical fiber 4 is used to connect to an external laser generator through the first outlet 301.

[0046] By connecting both the guidewire and optical fiber to the outside through the first outlet, an outlet structure is reduced, thus lowering production costs. At the same time, this design eliminates the need for an opening in the ring structure for the guidewire to enter, simplifying the ring structure. The guidewire also enters the ring structure without bending, resulting in smoother conduction of the guidewire.

[0047] like Figure 4 , Figure 5 As shown, in this embodiment, the catheter seat 3 is provided with a balloon inflation interface 302; the photodynamic balloon catheter includes a balloon 1, which is connected to the distal end of the catheter body 2; a balloon inflation cavity 6 is formed between the catheter body 2 and the annular structure, with one end of the balloon inflation cavity 6 communicating with the balloon inflation interface 302 and the other end communicating with the balloon 1. The balloon inflation cavity 6 formed by the annular structure and the catheter body 2 allows for the inflation and deflation of the balloon 1, causing it to expand or contract, simplifying the structure of the catheter body 2 and reducing the production cost of the photodynamic balloon catheter.

[0048] In this embodiment, a thin film 5 covers the outer side of the annular structure, and a balloon filling cavity 6 is formed between the catheter body 2 and the thin film 5. The thin film 5 protects the annular structure, thereby improving its strength and extending the service life of the photodynamic balloon catheter. Alternatively, the thin film 5 may not be provided on the outside of the annular structure.

[0049] In this embodiment, as Figure 4 As shown, the annular structure is fixedly connected to the film 5. Fixing the annular structure to the film 5 further increases the strength of the annular structure and improves the service life of the photodynamic balloon catheter. Alternatively, multiple optical fibers 4 can be fixedly connected solely by mutual bonding, without being fixedly connected to the film 5. In other alternative embodiments where the film 5 covers the outside of the annular structure, the optical fibers 4 can also be fixed by a ring-shaped cable management frame. All methods of fixing multiple optical fibers 4 into an annular structure are optional solutions, and no further limitations are imposed here.

[0050] In this embodiment, the outer surface of the balloon 1 is coated with a vascular repair-promoting coating, which includes vascular repair-promoting materials. This coating induces cross-linking of proteins within the blood vessel wall, forming a natural vascular scaffold, thereby maintaining the dilated blood vessel.

[0051] Specifically, angiogenic repair materials include naphthalimide dimers and their derivatives.

[0052] In this embodiment, the outer surface of the balloon 1 is further coated with a drug coating that inhibits restenosis, which is used to treat vascular stenosis and occlusion. As an alternative implementation, the outer surface of the balloon 1 may only be coated with a vascular repair-promoting coating, without the drug coating that inhibits restenosis.

[0053] Specifically, the restenosis-inhibiting drug coating includes macrolide immunosuppressants, macrolide antibiotics, rapamycin, structural derivatives and functional analogs of rapamycin, everolimus, structural derivatives and functional analogs of everolimus, paclitaxel, taxanes, zoromolimus, everolimus, sirolimus, biolimus, tacrolimus, tamsulosin, and tamsulosin compounds. Alternatively, the restenosis-inhibiting drug coating may include at least one of the above-mentioned drugs.

[0054] In use, the photodynamic balloon catheter is guided by a guidewire to the lesion site in the blood vessel. Then, balloon 1 is delivered to the lesion site. Balloon 1 can be inflated through the balloon inflation chamber 6, allowing it to expand and contact the lesion tissue, thus enabling the vascular repair material to reach the lesion tissue. Then, optical fiber 4 is connected to an external laser generator, causing optical fiber 4 to emit light with a wavelength of 400-500nm, which activates the vascular repair material and triggers cross-linking of proteins in the blood vessel wall, forming a natural vascular scaffold, which allows the dilated blood vessel to be maintained. Finally, the balloon 1 is depressurized and withdrawn from the body.

[0055] Although embodiments of the present invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the present invention, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. A photodynamic balloon catheter, characterized in that, include: The catheter body (2) has a receiving space inside; Multiple optical fibers (4) are disposed within the accommodating space. The multiple optical fibers (4) form a hollow ring structure around a circle. The ring structure is used to constitute the accommodating structure of the guide wire. The ring structure is suitable for the guide wire to pass through.

2. The photodynamic balloon catheter according to claim 1, characterized in that, The multiple optical fibers (4) are fixed together by adhesive bonding.

3. The photodynamic balloon catheter according to claim 1, characterized in that, The cross-section of the optical fiber (4) is circular, and the diameter of the optical fiber (4) is 0.1 mm to 1 mm. 。 4. The photodynamic balloon catheter according to claim 1, characterized in that, The photodynamic balloon catheter includes: The catheter seat (3) is connected to the proximal end of the catheter body (2). The catheter seat (3) is a hollow structure. The catheter seat (3) is provided with a first outlet (301). The hollow cavity of the annular structure is connected to the first outlet (301). The guide wire is connected to the outside through the first outlet (301). One end of the optical fiber (4) is used to connect to an external laser generator through the first outlet (301).

5. The photodynamic balloon catheter according to claim 4, characterized in that, The catheter seat (3) is provided with a balloon inflation port (302); The photodynamic balloon catheter includes a balloon (1) which is connected to the distal end of the catheter body (2); A balloon filling cavity (6) is formed between the catheter body (2) and the annular structure. One end of the balloon filling cavity (6) is connected to the balloon filling interface (302), and the other end is connected to the balloon (1).

6. The photodynamic balloon catheter according to claim 5, characterized in that, The annular structure is covered by a thin film (5), and the balloon filling cavity (6) is formed between the catheter body (2) and the thin film (5).

7. The photodynamic balloon catheter according to claim 6, characterized in that, The annular structure is fixedly connected to the thin film (5).

8. The photodynamic balloon catheter according to any one of claims 1-7, characterized in that, The outer surface of the balloon (1) is coated with a vascular repair coating, which includes vascular repair materials.

9. The photodynamic balloon catheter according to any one of claims 1-7, characterized in that, The outer surface of the balloon (1) is provided with a drug coating that inhibits restenosis, which is used to treat vascular stenosis and occlusion.

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