Vacuum drying equipment for cimetidine dicondensate production

Abstract

The utility model discloses vacuum drying equipment for cimetidine dicondensate production, which comprises a bottom frame, the upper surface of the bottom frame is fixedly connected with a rotary transmission device, the rotary transmission device comprises a motor, the output end of the motor is fixedly connected with a first rotating shaft, one end of the first rotating shaft is fixedly connected with a driving belt wheel, and the other end of the first rotating shaft is fixedly connected with a second belt wheel. The outer surface of the driving belt wheel is sleeved with a belt, one end of the belt is sleeved with a driven belt wheel, a second rotating shaft is connected into the driven belt wheel in a penetrating mode, and the two ends of the second rotating shaft are fixedly connected with a second bearing seat and a third bearing seat. A chain wheel is connected to the interior of the second rotating shaft in a penetrating mode, evaporation of water is accelerated by rolling over materials in the rotating cylinder, arranging the heating and drying device and making contact with the hot surface, and by arranging the rotary transmission device, the materials can be evenly heated, caked materials can be scattered, and the drying efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical production equipment technology, and in particular to a vacuum drying equipment for the production of cimetidine dimethyl ether. Background Technology

[0002] Cimetidine dimethyl ester is the main raw material for the production of cimetidine. Cimetidine is a first-generation histamine H2 receptor antagonist with strong inhibitory effects on gastric acid secretion and protective effects on the digestive tract mucosa. It has long been used for the prevention and treatment of peptic ulcers and upper gastrointestinal bleeding. Cimetidine also participates in the body's immune response, modulates the body's immune function, and has a certain broad-spectrum antiviral effect, thus being widely used as an adjunct treatment for various allergic diseases and viral infections. Cimetidine has definite clinical efficacy, a wide range of applications, and is very inexpensive, making it highly favored by the market and possessing a promising market prospect.

[0003] Existing vacuum drying equipment often only dries the surface of raw materials, leaving materials that have condensed into lumps due to moisture incompletely dried, affecting product quality. Furthermore, traditional dryers are slow, reducing productivity. For example, Chinese patent disclosure "A Rotary Vacuum Dryer for Pharmaceutical Production" (application number: CN202220891461.2) includes: a support frame made of channel steel and a cavity formed by an inner liner and a jacket. A rotary shaft is fixedly connected to both ends of the jacket, passing through a bearing seat and connected to a bearing. A drain outlet is located on one side of the jacket, connected to a water pipe inside the rotary shaft. A vacuum tube is located inside the rotary shaft on the side away from the drain outlet. This device often only dries the surface of raw materials, leaving materials that have condensed into lumps due to moisture incompletely dried, affecting product quality. Moreover, traditional dryers are slow, reducing productivity and limiting applicability. Utility Model Content

[0004] The purpose of this utility model is to at least solve one of the technical problems existing in the prior art, and to provide a vacuum drying equipment for the production of cimetidine dimethyl ether. This device accelerates the evaporation of moisture by tumbling the material in a rotating drum and by setting up a heating and drying device to contact the hot surface. By setting up a rotary transmission device, the material can be heated evenly and agglomerated materials can be broken up, thereby improving the drying efficiency.

[0005] This utility model also provides a vacuum drying device for the production of cimetidine dicondensate, comprising: a base frame, a rotary transmission device fixedly connected to the upper surface of the base frame, the rotary transmission device comprising: a motor, a first rotating shaft fixedly connected to the output end of the motor, a drive pulley fixedly connected to one end of the first rotating shaft, a belt sleeved on the outer surface of the drive pulley, a driven pulley sleeved at one end of the belt, a second rotating shaft penetrating through the interior of the driven pulley, and a second bearing seat and a third bearing seat fixedly connected to both ends of the second rotating shaft; through the cooperation between the above parts, the material can be heated evenly, and agglomerated materials can be broken up, thereby improving drying efficiency.

[0006] A sprocket is internally connected to the second rotating shaft, a rotating cylinder is fixedly connected to the upper surface of the base frame, and a chain is fixedly connected to the outer surface of the rotating cylinder. The chain meshes with the sprocket. The cooperation between these components facilitates the rotation of the material inside the rotating cylinder.

[0007] According to the present invention, a vacuum drying device for the production of cimetidine dicondensate includes a convex strip fixedly connected to the outer surface of the rotating cylinder, and a rotating roller fixedly connected to the upper surface of the base frame, the rotating roller engaging with the convex strip. This interlocking of the components reduces friction in the transmission device and extends its service life.

[0008] According to the vacuum drying equipment for producing cimetidine dimethyl ether, one end of the first rotating shaft is fixedly connected to a first bearing seat, and a ball bearing is fixedly connected to the inner surface of the first bearing seat. The cooperation between these parts facilitates the rotation of the rotating drum, ensuring uniform drying of the material.

[0009] According to the vacuum drying equipment for the production of cimetidine dicondensate described in this utility model, a feed funnel is fixedly connected to the top of the side surface of the rotating cylinder, and the inner surface of the feed funnel is inclined. Through the cooperation between the above-mentioned parts, the material can be moved by gravity.

[0010] According to the present invention, a vacuum drying device for the production of cimetidine dicondensate includes a heating and drying device fixedly connected to the side surface of the rotating drum. The heating and drying device comprises a heating rod, and a blower is fixedly connected to the end away from the heating rod. Through the cooperation of these components, moisture evaporation is accelerated by contact with the heated surface.

[0011] According to the vacuum drying equipment for the production of cimetidine dicondensate described in this utility model, a cover plate is fixedly connected to the side surface of the blower, and a heat dissipation groove is formed on the side surface of the cover plate. Through the cooperation between the above-mentioned parts, the drying efficiency of the material is accelerated, and the heat dissipation groove facilitates the dissipation of heat generated during the operation of the blower.

[0012] According to the vacuum drying equipment for the production of cimetidine dimethyl ether, a spiral separator is fixedly connected to the inner surface of the rotating cylinder, and a discharge port is provided at the bottom end of the side surface of the rotating cylinder. The cooperation between these components facilitates the breaking up of agglomerated materials.

[0013] According to the present invention, a vacuum drying device for the production of cimetidine dimethyl ether (CME) comprises a vacuum unit fixedly connected to the upper surface of the base frame, and a vacuum tube fixedly connected to the output end of the vacuum unit. Through the cooperation of these components, the vacuum tube facilitates the creation of a vacuum state inside the rotating drum, thereby accelerating the evaporation of moisture from the material.

[0014] Beneficial effects

[0015] Compared with the prior art, this utility model accelerates the evaporation of moisture by tumbling the material in a rotating drum, setting up a heating and drying device, and setting up a rotary transmission device to ensure that the material is heated evenly and can break up clumps of material, thereby improving drying efficiency. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments;

[0017] Figure 1 This is an overall structural diagram of the vacuum drying equipment for the production of cimetidine dicondensate according to this utility model;

[0018] Figure 2 This is a structural diagram of the rotary transmission device of the vacuum drying equipment for the production of cimetidine dicondensate according to this utility model;

[0019] Figure 3 This utility model relates to a vacuum drying device for the production of cimetidine dicondensate. Figure 1 Enlarged view of point A in the middle;

[0020] Figure 4 This utility model relates to a vacuum drying device for the production of cimetidine dicondensate. Figure 1 Enlarged view at point B in the middle;

[0021] Figure 5 This is a structural diagram of the heating and drying device of the vacuum drying equipment for the production of cimetidine dicondensate according to this utility model.

[0022] Figure 6This is a diagram showing the internal structure of the rotating cylinder of the vacuum drying equipment for the production of cimetidine dimethyl ...

[0023] Legend:

[0024] 1. Base frame; 2. Rotating cylinder; 3. Convex strip; 4. Rotating roller; 5. Motor; 6. First rotating shaft; 7. First bearing housing; 8. Driving pulley; 9. Belt; 10. Driven pulley; 11. Second bearing housing; 12. Third bearing housing; 13. Second rotating shaft; 14. Sprocket; 15. Chain; 16. Feed hopper; 17. Blower; 18. Heating rod; 19. Cover plate; 20. Discharge port; 21. Vacuum machine; 22. Vacuum tube; 23. Spiral separator. Detailed Implementation

[0025] This section will describe in detail the specific embodiments of the present utility model. The preferred embodiments of the present utility model are shown in the accompanying drawings. The purpose of the drawings is to supplement the textual description with graphics, so that people can intuitively and vividly understand each technical feature and the overall technical solution of the present utility model, but they should not be construed as limiting the scope of protection of the present utility model.

[0026] Reference Figure 1-6 This utility model discloses a vacuum drying device for the production of cimetidine dimethyl ether, comprising: a base frame 1, a vacuum machine 21 fixedly connected to the upper surface of the base frame 1, and a vacuum tube 22 fixedly connected to the output end of the vacuum machine 21, so as to facilitate the vacuum tube 22 to create a vacuum inside the rotating cylinder 2, thereby accelerating the evaporation of moisture from the material; a rotary transmission device fixedly connected to the upper surface of the base frame 1, the rotary transmission device comprising: a motor 5, a first rotating shaft 6 fixedly connected to the output end of the motor 5, and a first shaft fixedly connected to one end of the first rotating shaft 6. The inner surface of the bearing seat 7 and the first bearing seat 7 is fixedly connected with a ball bearing, which facilitates the rotation of the rotating drum 2 and makes the material dry evenly. One end of the first rotating shaft 6 is fixedly connected with a drive pulley 8. The outer surface of the drive pulley 8 is fitted with a belt 9. One end of the belt 9 is fitted with a driven pulley 10. The interior of the driven pulley 10 is connected to a second rotating shaft 13. The two ends of the second rotating shaft 13 are fixedly connected with a second bearing seat 11 and a third bearing seat 12, which allows the material to be heated evenly and can break up agglomerated materials, thereby improving drying efficiency.

[0027] A sprocket 14 is internally connected to the second rotating shaft 13. A rotating cylinder 2 is fixedly connected to the upper surface of the base frame 1. A spiral separator 23 is fixedly connected to the inner surface of the rotating cylinder 2. A discharge port 20 is opened at the bottom of the side surface of the rotating cylinder 2 to facilitate the breaking up of agglomerated materials. A heating and drying device is fixedly connected to the side surface of the rotating cylinder 2. The heating and drying device includes a heating rod 18, and a blower 17 is fixedly connected to the end away from the heating rod 18. The blower 17 accelerates the evaporation of moisture by contacting the hot surface. A cover plate 19 is fixedly connected to the side surface of the blower 17, and heat dissipation grooves are opened on the side surface of the cover plate 19. To accelerate the drying efficiency of materials, the heat dissipation groove facilitates the dissipation of heat generated by the blower 17 during operation. The top of the side surface of the rotating cylinder 2 is fixedly connected to the feed funnel 16. The inner surface of the feed funnel 16 is inclined, which facilitates the movement of materials by gravity. The outer surface of the rotating cylinder 2 is fixedly connected to the protrusion 3. The upper surface of the base frame 1 is fixedly connected to the rotating roller 4. The rotating roller 4 is engaged with the protrusion 3 to reduce the friction of the transmission device and extend its service life. The outer surface of the rotating cylinder 2 is fixedly connected to the chain 15. The chain 15 is engaged with the sprocket 14 to facilitate the rotation of the materials inside the rotating cylinder 2.

[0028] Working Principle: When using this device, the material first enters the equipment through the feed hopper 16 at one end of the rotary dryer. The inlet is inclined so that the material can move by gravity. By starting the motor 5, the first rotating shaft 6 is driven to rotate the drive pulley 8. The belt 9 is sleeved on the outer surface of the drive pulley 8, which in turn drives the driven pulley 10 to rotate. The second bearing seat 11 and the third bearing seat 12 are fixedly connected to the upper surface of the base frame 1, which drives the second rotating shaft 13 to rotate, which in turn drives the sprocket 14 to rotate. The engagement of the sprocket 14 and the chain 15 drives the rotating drum 2 to rotate, so that the material can be heated evenly. The spiral separator 23 fixedly connected to the inner surface of the rotating drum 2 can break up the clumps of material and improve the drying efficiency. A heating device is fixedly connected to one end of the side surface of the rotating drum 2. Starting the heating rod 18 and the blower 17 can accelerate the evaporation of moisture. As the material tumbles inside the rotating drum 2, the vacuum machine 21 is started, and the vacuum tube 22 creates a vacuum inside the rotating drum 2, thereby accelerating the evaporation of moisture from the material.

[0029] The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present utility model.

Claims

1. A vacuum drying apparatus for the production of cimetidine dicondensate, characterized in that, include: A base frame (1) is fixedly connected to a rotary transmission device on its upper surface. The rotary transmission device includes a motor (5), a first rotating shaft (6) is fixedly connected to the output end of the motor (5), a drive pulley (8) is fixedly connected to one end of the first rotating shaft (6), a belt (9) is sleeved on the outer surface of the drive pulley (8), a driven pulley (10) is sleeved on one end of the belt (9), a second rotating shaft (13) is connected through the interior of the driven pulley (10), and a second bearing seat (11) and a third bearing seat (12) are fixedly connected to both ends of the second rotating shaft (13). A sprocket (14) is connected through the interior of the second rotating shaft (13). A rotating cylinder (2) is fixedly connected to the upper surface of the base frame (1). A chain (15) is fixedly connected to the outer surface of the rotating cylinder (2). The chain (15) is engaged with the sprocket (14).

2. The vacuum drying equipment for producing cimetidine dimethyl ether as described in claim 1, characterized in that, The outer surface of the rotating cylinder (2) is fixedly connected with a protrusion (3), and the upper surface of the base frame (1) is fixedly connected with a rotating roller (4), which is engaged with the protrusion (3).

3. The vacuum drying equipment for the production of cimetidine dimethyl ether as described in claim 1, characterized in that, One end of the first rotating shaft (6) is fixedly connected to a first bearing seat (7), and a ball bearing is fixedly connected to the inner surface of the first bearing seat (7).

4. The vacuum drying equipment for the production of cimetidine dicondensate according to claim 1, characterized in that, The top of the side surface of the rotating cylinder (2) is fixedly connected to a feed funnel (16), and the inner surface of the feed funnel (16) is inclined.

5. The vacuum drying equipment for the production of cimetidine dimethyl ether as described in claim 1, characterized in that, A heating and drying device is fixedly connected to the side surface of the rotating cylinder (2). The heating and drying device includes a heating rod (18) and a blower (17) is fixedly connected to the end away from the heating rod (18).

6. The vacuum drying equipment for the production of cimetidine dimethyl ether as described in claim 5, characterized in that, A cover plate (19) is fixedly connected to the side surface of the blower (17), and a heat dissipation groove is provided on the side surface of the cover plate (19).

7. The vacuum drying equipment for the production of cimetidine dimethyl ether as described in claim 1, characterized in that, The inner surface of the rotating cylinder (2) is fixedly connected to a spiral separator (23), and the bottom end of the side surface of the rotating cylinder (2) is provided with a discharge port (20).

8. The vacuum drying equipment for the production of cimetidine dimethyl ether as described in claim 1, characterized in that, A vacuum machine (21) is fixedly connected to the upper surface of the base frame (1), and a vacuum tube (22) is fixedly connected to the output end of the vacuum machine (21).

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