Cylinder structure for continuous chromatography

Abstract

The utility model relates to the technical field of chromatography, and discloses a barrel structure for continuous chromatography, which comprises a barrel body, two ends of the barrel body are fixedly connected with first connecting ends, one side, far away from the barrel body, of each first connecting end is attached with a second connecting end, and one side, far away from the first connecting end, of each second connecting end is fixedly connected with a connector. A sealing assembly is fixedly connected into the first connecting end and comprises an inserting plate inserted into the first connecting end, a sealing gasket is fixedly connected to the end, away from the first connecting end, of the inserting plate, an inserting block is inserted into the end, away from the sealing gasket, of the inserting plate, and a bearing ring is fixedly connected to the outer side of the inserting block. The two ends of the bearing ring are rotationally connected into the first connecting end, the sealing effect of the sealing position of the connecting position of the first connecting end and the second connecting end is enhanced, the conditions of displacement and the like of the sealing gasket in the using process are avoided, accordingly, leakage of samples and mobile phases is reduced, and stability is improved.

Description

Technical Field

[0001] This utility model relates to the field of chromatography technology, specifically to a cylinder structure for continuous chromatography. Background Technology

[0002] Chromatography is a separation and analysis method based on the difference in the partition coefficients of different substances between the stationary phase and the mobile phase. For example, in liquid chromatography, the mobile phase is a liquid, and the stationary phase can be a solid adsorbent or a liquid chemically bonded to the surface of a support. When the sample mixture flows repeatedly between the two phases for partitioning, the different components move at different speeds, thereby achieving continuous separation. The cylindrical structure used for chromatographic separation is a device used to place the chromatogram and facilitate sample flow.

[0003] Chromatographic separation cylinders are generally designed as straight cylinders, while liquid chromatography is filled inside the cylinder. Sealing gaskets are inserted inside both ends of the cylinder, and bolts are used to fix the two ends of the cylinder to the connection ends of other equipment. The sealing gaskets are used to seal the connection to prevent the sample and liquid chromatography from flowing out of the cylinder.

[0004] Traditional chromatographic separation cylinders use a direct insertion method for the sealing gaskets at both ends. While this method allows for restriction via the connection points at both ends of the cylinder and other equipment, the sealing gaskets still have some room to rotate or shift. Therefore, when the sealing gaskets rotate due to external vibration or shaking, gaps can easily appear at the connection points, reducing the sealing effect and causing leakage of mobile phase and sample, resulting in material loss and affecting the operation of surrounding equipment. Utility Model Content

[0005] The purpose of this invention is to provide a cylinder structure for continuous chromatography, which solves the problem that in the existing continuous chromatography cylinder structure, the sealing gasket has poor limiting effect after installation and is easily displaced by external forces, resulting in leakage of sample and mobile phase.

[0006] This utility model provides the following technical solution: a cylinder structure for continuous chromatography, including a barrel body, with a first connecting end fixedly connected to both ends of the barrel body, and a second connecting end attached to the side of the first connecting end away from the barrel body, an interface fixedly connected to the side of the second connecting end away from the first connecting end, and a sealing component fixedly connected inside the first connecting end, and the sealing component including an insert plate inserted inside the first connecting end, and a sealing gasket fixedly connected to the end of the insert plate away from the first connecting end.

[0007] The above technical solution uses a insert plate and a sealing gasket to seal the connection between the first and second connecting ends.

[0008] As a preferred embodiment of the above technical solution, an insert block is inserted into the end of the insert plate away from the sealing gasket, and a bearing ring is fixedly connected to the outside of the insert block. The two ends of the bearing ring are rotatably connected to the first connecting end.

[0009] The above technical solution enhances the stability of the insertion plate by inserting multiple sets of insert blocks into it.

[0010] As a preferred embodiment of the above technical solution, a pressure plate is fixedly connected to the side of the bearing ring away from the insert block, and a spring is fixedly connected to the middle end of the pressure plate. A first baffle is fixedly connected to the end of the spring away from the pressure plate, and the end of the first baffle away from the bearing ring is fixedly connected to the first connecting end.

[0011] The above technical solution facilitates the return of the bearing ring and insert block by using a pressure plate, spring, and first baffle.

[0012] As a preferred embodiment of the above technical solution, a transmission plate is fixedly connected to one end of the bearing ring, and a push plate is fixedly connected to the end of the transmission plate away from the bearing ring through the first connection end.

[0013] The above technical solution can drive the push plate to rotate and move the transmission plate and bearing ring.

[0014] As a preferred embodiment of the above technical solution, a fixing component is provided at the outer ends of the first connecting end and the second connecting end, and the fixing component includes a second baffle provided at the outer end of the second connecting end, and a threaded rod is fixedly connected to the side of the second baffle near the second connecting end.

[0015] The above technical solution utilizes a second baffle and a threaded rod to position and restrict the connection between the first and second connecting ends.

[0016] As a preferred embodiment of the above technical solution, an anti-slip pad is provided on the outer side of the end of the threaded rod away from the second baffle, and a bolt is attached to the side of the anti-slip pad away from the first connecting end, with the inner side of the bolt engaging the outer side of the threaded rod.

[0017] The threaded rod is fixed by bolts using the above technical solution.

[0018] Compared with the prior art, the beneficial effects of this utility model are:

[0019] This continuous chromatography cylinder structure enhances the sealing effect at the connection between the first and second connecting ends through the cooperation of sealing and fixing components, preventing displacement of the sealing gasket during use, thereby reducing leakage of sample and mobile phase and improving stability. Attached Figure Description

[0020] Figure 1A schematic diagram of the overall structure of a cylindrical body for continuous chromatography;

[0021] Figure 2 This is a schematic diagram of a partial cross-sectional structure of a cylinder for continuous chromatography from a first-view perspective.

[0022] Figure 3 for Figure 2 Enlarged schematic diagram of the structure at point A in the middle;

[0023] Figure 4 This is a schematic diagram of a partial cross-sectional structure of a cylinder for continuous chromatography from a second perspective.

[0024] In the diagram: 1. Barrel body; 11. First connecting end; 12. Second connecting end; 13. Interface; 2. Sealing assembly; 21. Insert plate; 22. Sealing gasket; 23. Insert block; 24. Bearing ring; 25. Pressure plate; 26. Spring; 27. First baffle; 28. Transmission plate; 29. ​​Push plate; 3. Fixing assembly; 31. Second baffle; 32. Threaded rod; 33. Anti-slip pad; 34. Bolt. Detailed Implementation

[0025] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0026] like Figure 1 - Figure 4 As shown, this utility model provides a technical solution: a cylinder structure for continuous chromatography, including a cylinder body 1, with a first connecting end 11 fixedly connected to both ends of the cylinder body 1, and a second connecting end 12 attached to the side of the first connecting end 11 away from the cylinder body 1. An interface 13 is fixedly connected to the side of the second connecting end 12 away from the first connecting end 11, and a sealing component 2 is fixedly connected inside the first connecting end 11. The sealing component 2 includes an insert plate 21 inserted inside the first connecting end 11, and a sealing gasket 22 is fixedly connected to the end of the insert plate 21 away from the first connecting end 11. This enhances the sealing effect at the connection point of the first connecting end 11 and the second connecting end 12, prevents the sealing gasket 22 from shifting during use, thereby reducing leakage of the sample and mobile phase and improving stability.

[0027] like Figure 3 As shown, a plug block 23 is inserted into the end of the insert plate 21 away from the sealing gasket 22, and a bearing ring 24 is fixedly connected to the outside of the plug block 23. The two ends of the bearing ring 24 are rotatably connected in the first connecting end 11. The bearing ring 24 pushes the plug block 23 to move, so that the plug block 23 is inserted into the insert plate 21 for restriction.

[0028] like Figure 3As shown, a pressure plate 25 is fixedly connected to the side of the bearing ring 24 away from the insert block 23, and a spring 26 is fixedly connected to the middle of the pressure plate 25. A first baffle 27 is fixedly connected to the end of the spring 26 away from the pressure plate 25, and the end of the first baffle 27 away from the bearing ring 24 is fixedly connected to the first connecting end 11. The spring 26 is squeezed by the movement of the pressure plate 25 with the assistance of the first baffle 27. Subsequently, the elastic potential energy of the spring 26 is used to push the bearing ring 24 and the insert block 23 back to their original positions.

[0029] like Figure 3 As shown, a transmission plate 28 is fixedly connected to one end of the bearing ring 24, and a push plate 29 is fixedly connected to the end of the transmission plate 28 away from the bearing ring 24 through the first connection end 11. The transmission plate 28 can be moved by pushing the push plate 29, thereby moving the insert plate 21 through the transmission plate 28.

[0030] like Figure 4 As shown, a fixing component 3 is provided at the outer ends of the first connecting end 11 and the second connecting end 12, and the fixing component 3 includes a second baffle 31 provided at the outer end of the second connecting end 12. A threaded rod 32 is fixedly connected to the side of the second baffle 31 near the second connecting end 12. The threaded rod 32 is driven by the second baffle 31 to pass through the first connecting end 11 and the second connecting end 12, which facilitates the positioning and restriction of the first connecting end 11 and the second connecting end 12.

[0031] like Figure 4 As shown, an anti-slip pad 33 is fitted on the outer side of the threaded rod 32 away from the second baffle 31, and a bolt 34 is attached to the side of the anti-slip pad 33 away from the first connecting end 11. The inner side of the bolt 34 is engaged with the outer side of the threaded rod 32. The threaded rod 32 can be fixed by using the anti-slip pad 33 and the bolt 34.

[0032] Working principle: When installing the barrel body 1 and the second connecting end 12, first insert the insert plate 21, which drives the sealing gasket 22, into the first connecting end 11. Before inserting the insert plate 21, press the push plate 29 to rotate the transmission plate 28 and the bearing ring 24. After the bearing ring 24 rotates, it drives the pressure plate 25 to compress the spring 26 with the assistance of the first baffle 27. At the same time, the rotation of the bearing ring 24 drives the insert block 23 to move. Then, after the insert plate 21 is inserted, it is fitted onto the outside of the insert block 23. After the insert plate 21 is inserted, it is released. Push plate 29, at this time, with the elastic potential energy of spring 26, push bearing ring 24 back to its original position, so that insert block 23 is inserted into insert plate 21 for locking. Then, release the pressed insert plate 21 and sealing washer 22, and then put second connecting end 12 on the outside of sealing washer 22. Then, the second baffle 31 drives threaded rod 32 through the second connecting end 12 and the first connecting end 11. Then, put anti-slip pad 33 on the outside of threaded rod 32. Finally, screw bolt 34 on the outside of threaded rod 32 for fixation.

[0033] The above embodiments are only used to illustrate the technical solution of this utility model, and are not intended to limit it.

Claims

1. A cylindrical structure for continuous chromatography, comprising a barrel body (1), characterized in that: The barrel body (1) is fixedly connected to two ends of a first connecting end (11), and a second connecting end (12) is attached to the side of the first connecting end (11) away from the barrel body (1). An interface (13) is fixedly connected to the side of the second connecting end (12) away from the first connecting end (11). A sealing component (2) is fixedly connected inside the first connecting end (11), and the sealing component (2) includes an insert plate (21) inserted inside the first connecting end (11). A sealing gasket (22) is fixedly connected to the end of the insert plate (21) away from the first connecting end (11).

2. The cylindrical structure for continuous chromatography according to claim 1, characterized in that: The insert plate (21) has an insert block (23) inserted inside the end away from the sealing gasket (22), and a bearing ring (24) is fixedly connected to the outside of the insert block (23). The two ends of the bearing ring (24) are rotatably connected inside the first connecting end (11).

3. The cylindrical structure for continuous chromatography according to claim 2, characterized in that: A pressure plate (25) is fixedly connected to the side of the bearing ring (24) away from the insert block (23), and a spring (26) is fixedly connected to the middle end of the pressure plate (25). A first baffle (27) is fixedly connected to the end of the spring (26) away from the pressure plate (25), and the end of the first baffle (27) away from the bearing ring (24) is fixedly connected to the first connecting end (11).

4. The cylindrical structure for continuous chromatography according to claim 3, characterized in that: One end of the bearing ring (24) is fixedly connected to a transmission plate (28), and the end of the transmission plate (28) away from the bearing ring (24) passes through the first connecting end (11) and is fixedly connected to a push plate (29).

5. The cylindrical structure for continuous chromatography according to claim 1, characterized in that: The first connecting end (11) and the second connecting end (12) are provided with a fixing component (3), and the fixing component (3) includes a second baffle (31) provided at the outer end of the second connecting end (12), and a threaded rod (32) is fixedly connected to the side of the second baffle (31) near the second connecting end (12).

6. The cylindrical structure for continuous chromatography according to claim 5, characterized in that: An anti-slip pad (33) is fitted on the outer side of the threaded rod (32) away from the second baffle (31), and a bolt (34) is attached to the side of the anti-slip pad (33) away from the first connecting end (11), with the inner side of the bolt (34) meshing with the outer side of the threaded rod (32).

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