Minimally invasive device for bone tissue biopsy

Abstract

The utility model discloses a bone tissue biopsy minimally invasive device, including sampling subassembly, cutting subassembly and cannula subassembly, sampling subassembly includes sampling piece and install the sampling handle on the sampling piece, cannula subassembly includes along the vertical direction set sleeve and along the horizontal direction set handle, the handle is installed on the top of sleeve, and the cutting subassembly is installed on the top of sleeve. The sampling piece extends into the sleeve, and the cutting assembly is installed at the bottom of the sleeve and connected with the sampling piece. The bone taking device can remarkably shorten the bone taking time, reduce trauma of the bone taking part and improve the efficiency and the curative effect of an autologous bone grafting operation at the same time.

Description

TECHNICAL FIELD

[0001] The utility model relates to orthopedics medical instrument technical field, concretely relates to a kind of bone tissue biopsy minimally invasive device. BACKGROUND

[0002] Pathological diagnosis has intuitiveness and objectivity, and is the "gold standard" in clinical medical diagnosis. Biopsy, which is short for living tissue examination, refers to the need for diagnosis and / or treatment, using cutting, pinching, suction or puncture to take the diseased tissue from the patient's body, and conducting pathological examination to provide important basis for disease diagnosis and subsequent treatment, prognosis evaluation and efficacy evaluation. Among them, living tissue examination includes autologous iliac bone tissue biopsy, vertebral body bone tissue biopsy, tumor bone metastasis biopsy, etc.

[0003] Autologous bone grafting is a common auxiliary operation in orthopedic surgery. In spinal surgery, autologous bone grafting can be used as a filler for intervertebral fusion, or can be transplanted alone around the vertebral body to promote the fusion of adjacent segments. In trauma surgery, autologous bone grafting can fill the bone defect of the transplantation site, treat bone nonunion and delayed fracture healing, such as common tibial and fibular bone nonunion, clavicular bone nonunion, etc., and can also treat fractures with cancellous bone compression and joint surface collapse, such as calcaneal fracture, tibial plateau fracture, distal radius fracture, etc. Although there are many autologous bone substitutes available for bone grafting in clinical applications, such as allogeneic bone, xenogeneic bone, artificial bone, etc., autologous bone has unparalleled biocompatibility and osteogenic activity because it comes from the recipient's own body and contains osteoblasts. It is not prone to rejection and can help restore the normal morphology and function of the graft area in a short period of time. It is recognized as the best bone grafting material and is most widely used in clinical applications. However, although autologous bone transplantation is widely used in orthopedic surgery, there is no specialized surgical tool for autologous bone harvesting in clinical practice. Taking the most commonly used iliac bone harvesting surgery as an example, bone knives and spatulas are often used to harvest bone during surgery. The operator usually hits the bone knife with a hammer near the anterior superior iliac spine, chisels through the bone cortex and marks the bone harvesting area according to the volume of bone needed, removes or lifts the cortical bone, and then uses a spatula to scrape the required amount of cancellous bone. This bone harvesting method has many drawbacks. First, the window area, bone volume and shape are often difficult to control accurately. Second, there is a risk of slipping, damaging or pressing the peritoneum when the bone knife is chiseled, and there is a risk of hanging the opposite bone cortex and damaging the organs when the spatula is scraped, resulting in a high incidence of bone harvesting-related complications. Accordingly, in order to harvest the appropriate size, quantity and shape of autologous bone and reduce complications, bone harvesting needs to be done carefully, in small quantities and multiple times, which consumes a lot of time. In addition, in order to expose enough vision, the traditional bone harvesting method usually requires a cut of more than 3 cm, and the wound-related complication rate at the bone harvesting site after surgery is high.

[0004] Vertebral biopsy is based on taking a small part of tissue sample from the vertebral body for intraoperative and postoperative pathological identification. With the development and progress of minimally invasive spinal surgery techniques and intraoperative fluoroscopy techniques, today, percutaneous transpedicular vertebral biopsy can be realized, which is widely used in percutaneous vertebroplasty and percutaneous kyphoplasty for treating spinal fractures and becomes the gold standard for diagnosing pathological spinal compression fractures. However, although vertebral biopsy is very popular in spinal surgery, some surgical tools specially used for vertebral biopsy have appeared in clinical practice, but most of them are not ideal in actual application. Taking the biopsy tool used in percutaneous vertebroplasty as an example, the most commonly used one is a front-end sawtooth-shaped, hollow cylindrical metal straight tube. First, the surgeon uses a puncture tool to establish a working channel through the pedicle to the vertebral body, then the surgeon slowly advances the biopsy straight tube through the pedicle, in the process of advancing, the tissue in the vertebral body enters the straight tube, when the front end of the straight tube reaches the appropriate depth or the target lesion, the surgeon rotates the straight tube, the front-end sawtooth cuts the tissue in the front-end straight tube and the tissue outside the straight tube, finally, the straight tube is withdrawn, and the tissue taken in the straight tube is taken out for examination. Although such biopsy tool is simple to operate, but in clinical use, only a small amount of pathological tissue can be taken, and the tissue is often left in the vertebral body when the tube is pulled out, and finally the pathological tissue is not taken out.

[0005] Tumor bone metastasis refers to that some malignant tumors originating from bone tissue outside are transferred to bone tissue through blood, and gradually form new tumor lesions after planting, destroy normal bone tissue, and cause diseases mainly manifested as pain, hypercalcemia, pathological fracture and nerve compression. Through statistical analysis, among common malignant tumors, breast cancer, prostate cancer and thyroid cancer have the highest bone metastasis rate, about 60-75%, which is the first echelon. Lung cancer, renal cancer, liver cancer and malignant melanoma are the second, about 20-45%. Digestive tract tumors such as gastric cancer, colorectal cancer and gynecological tumors can also have bone metastasis, and the incidence is generally less than 10%. In tumor bone metastasis, the spine is the most easily invaded site. In clinical work, for pathological spinal compression fractures, percutaneous puncture instruments are often used to take the bone tissue in the vertebral body for pathological section analysis to determine which primary tumor metastasis comes from, and the currently used tool is only a common cannula. When the cannula is knocked into the vertebral body, it often cannot carry the pathological tissue out when it is pulled out, and the bone tissue cannot be effectively clamped, so as to cause low diagnostic accuracy and high misdiagnosis rate.

[0006] Therefore, how to solve the problems existing in the prior art has become the research and solution of the present application. Practical new type content

[0007] Therefore, the purpose of the present application is to provide a bone tissue biopsy minimally invasive device.

[0008] To achieve the above object, the utility model adopts the technical scheme that is:

[0009] A kind of bone tissue biopsy minimally invasive device, including sampling assembly, cutting assembly and sleeve assembly, the sampling assembly includes sampling piece and the sampling handle installed on the sampling piece, the sleeve assembly includes sleeve that is arranged along vertical direction and handle that is arranged along horizontal direction, the handle is installed at the top of the sleeve;The sampling piece extends into the sleeve, the cutting assembly is installed at the bottom of the sleeve, and the cutting assembly is connected with the sampling piece.

[0010] Further, the inner wall of the sleeve is provided with a threaded part.

[0011] Further, the cutting assembly includes a cylindrical bone extractor, the wall thickness of the bone extractor decreases from top to bottom, a plurality of bone knives are sequentially installed on the inner wall of the bone extractor in the circumferential direction, and the bone knives are arranged perpendicularly to the inner wall of the bone extractor;The bone extractor is connected with the bottom of the sleeve, and the bone extractor communicates with the sleeve.

[0012] Further, a baffle is installed on the end of the sampling piece away from the sampling handle, the sampling piece and the baffle both extend into the sleeve, the sampling piece is threadedly connected with the inner wall of the sleeve through the threaded part, and the sampling piece moves up and down when rotating;The baffle changes position driven by the sampling piece, when the sampling piece rotates to the top of the threaded part, the baffle is located at the top of the bone extractor, and when the sampling piece rotates to the bottom of the threaded part, the baffle is located at the bottom of the bone extractor.

[0013] Further, when the sampling piece rotates clockwise, the baffle descends, and when the sampling piece rotates counterclockwise, the baffle rises.

[0014] Further, the cutting surface of the handle is inverted triangular.

[0015] Further, a pipeline is arranged in the sleeve along the vertical direction, a C-shaped pipeline is arranged at the bottom of the sleeve, the pipeline communicates with the C-shaped pipeline, the cutting assembly includes a mosquito coil-shaped steel wire inner core, the sampling piece is a steel wire inner core, and the steel wire inner core extends into the pipeline to the C-shaped pipeline to rotate into the mosquito coil-shaped steel wire inner core.

[0016] Further, the cutting surface of the sleeve along the horizontal direction is elliptical.

[0017] Further, the cutting assembly includes a sawtooth-shaped septum, the sawtooth-shaped septum is installed at the bottom of the sleeve, and the sawtooth-shaped septum divides the bottom of the sleeve into two parts.

[0018] Further, the edge of the bottom of the sleeve is sawtooth-shaped.

[0019] Compared with the prior art, the advantages of this utility model are as follows: This application is designed according to the commonly used size and shape of autologous bone harvesting, the depth and volume of bone harvesting are adjustable, the operation is simple, the design is compact, and it is suitable for various surgeries that require autologous bone grafting, such as spinal surgery and trauma surgery. Compared with traditional bone scalpels and curettes, the bone harvesting is complete and aesthetically pleasing, the depth of bone harvesting is visible and quantifiable, the amount and shape of bone harvesting are easy to control, the bone harvesting process is safe, the required incision is smaller, the bone harvesting time can be significantly shortened, the trauma to the bone harvesting site can be reduced, and the efficiency and efficacy of autologous bone grafting surgery can be improved. Attached Figure Description

[0020] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Appendix Figure 1 This is a schematic diagram of the structure of an embodiment of this application;

[0022] Appendix Figure 2 This is a schematic diagram of the cross-sectional structure of the bone harvester according to an embodiment of this application;

[0023] Appendix Figure 3 This is a schematic cross-sectional view of an embodiment of this application;

[0024] Appendix Figure 4 This is a top view schematic diagram of an embodiment of this application;

[0025] Appendix Figure 5 This is a schematic diagram of the steel wire core structure according to an embodiment of this application;

[0026] Appendix Figure 6 This is a schematic diagram of the structure of the mosquito coil-shaped steel wire core according to an embodiment of this application;

[0027] Appendix Figure 7 This is a schematic longitudinal sectional view of an embodiment of this application;

[0028] Appendix Figure 8 This is a schematic cross-sectional view of an embodiment of this application.

[0029] Explanation of reference numerals and components in the accompanying drawings:

[0030] 1, sampling assembly; 11, sampling piece; 12, sampling handle; 13, baffle; 14, steel wire inner core; 15, annular handheld handle; 2, cutting assembly; 21, bone extractor; 22, bone cutter; 23, mosquito coil-shaped steel wire inner core; 3, tube sleeve assembly; 31, sleeve; 32, handle; 33, thread; 34, T-shaped working sleeve; 35, pipe; 36, C-shaped pipe; 4, T-shaped rotating handle; 5, oval straight cylinder; 6, septum; 7, distal edge. DETAILED DESCRIPTION

[0031] The technical solutions of the present application will be described clearly and completely by specific embodiments. Obviously, the described embodiments are only some of the embodiments of the present application, not all. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0032] Referring to the accompanying drawings Figures 1-8 The present application provides a bone tissue biopsy minimally invasive device, which comprises a sampling assembly 1, a cutting assembly 2 and a sleeve assembly 3. The sampling assembly 1 comprises a sampling piece 11 and a sampling handle 12 installed on the sampling piece 11. The sleeve assembly 3 comprises a sleeve 31 arranged in the vertical direction and a handle 32 arranged in the horizontal direction. The handle 32 is installed on the top of the sleeve 31, and the sampling piece 11 extends into the sleeve 31. The cutting assembly 2 is installed at the bottom of the sleeve 31, and the cutting assembly 2 is connected with the sampling piece 11.

[0033] Embodiment 1:

[0034] Referring to the accompanying drawings Figure 1 and the accompanying drawings Figure 2As shown, the application is designed according to the common autologous bone shape, the inner wall of the sleeve 31 is provided with a thread 33, the sampling member 11 is a push rod, the push rod is threadedly connected with the sleeve 31 through the thread 33, the inner wall diameter of the sleeve 31 is 1 cm, the length of the thread 33 on the inner wall is 4 cm, the sleeve 31 is connected with the cutting assembly 2 below, the cutting assembly 2 includes a cylindrical bone cutter 21, the inner wall diameter of the bone cutter 21 at the lower end of the sleeve 31 is 1.6 cm, the height is 3 cm, a plurality of bone knives 22 are sequentially installed on the inner wall of the bone cutter 21 in the circumferential direction, the bone knives 22 in the embodiment have 6 groups, at the same time, the wall thickness of the bone cutter 21 gradually thins from 1 mm to 0.3 mm from top to bottom, the blade width of the bone knife 22 is 0.3 cm, the height is 3 cm, and the thickness is 0.3 mm. The bone knife 22 is arranged perpendicularly to the inner wall of the bone cutter 21, the cylindrical bone cutter 21 is connected with the bottom of the sleeve 31, and the bone cutter 21 communicates with the sleeve 31. In addition, in the embodiment, the upper end of the sleeve 31 is a handle 32 perpendicular to the sleeve 31, the sleeve 31 is provided with a handle 32 on the left and right, the handle 32 is a reverse triangular section, the length is 5 cm, the upper plane width is 1 cm, the handle 32 can be held, and can also be hammered by a hammer.

[0035] The sampling member 11 is provided with a baffle 13 at the end away from the sampling handle 12, the baffle 13 has a diameter of 1 cm, the sampling member 11 and the baffle 13 are inserted into the sleeve 31, the sampling member 11 is threadedly connected with the inner wall of the sleeve 31 through the thread 33, the sampling member 11 moves up and down when rotating, the baffle 13 is driven by the sampling member 31 to change the position, the push rod, that is, the middle shaft of the sampling member 31, is also provided with a thread with a length of 1 cm, which is tightly combined with the thread 33 on the inner wall of the sleeve 31, when the push rod is rotated to the uppermost end, the baffle 13 is located at the top of the bone taking device 21, when the push rod is rotated to the lowermost end, the baffle 13 is located at the bottom of the bone taking device 21, and the stroke is 3 cm. The sampling handle 12 has a diameter of 1 cm and a height of 3 cm, when the sampling handle 12 is rotated clockwise, the lower baffle 13 descends, and when the sampling handle 12 is rotated counterclockwise, the lower baffle 13 ascends. The bone taking device 21 can be slowly deepened by hammering the handle, the six groups of blades on the inner wall of the bone taking device 21 can cut the bone, so that the deepening process is smooth, when the baffle 13 blocks the deepening, it indicates that the bone taking depth has been reached, at this time, the bone taking device 21 can be easily disconnected and removed, and then the tool can be withdrawn, so the operation is simple. The bone taking depth can be controlled by adjusting the height of the lower baffle 13, so that the bone taking is not too deep to pierce the opposite bone cortex and damage the organs, and the operation is safe. The baffle 13 can also be advanced by rotating the sampling handle 12 clockwise, and then the bone graft is pushed out, so the operation is simple. The opening surface of the bone taking device 21 is a circle with a diameter of 1.6 cm and a height of 3 cm, which can be adjusted, so that the removed bone graft is in the shape of a cylinder with a diameter of 1.6 cm and a height of 3 cm, which conforms to the shape and size of the commonly used bone graft in clinic, and can be directly implanted without splicing in some common bone defect sites, such as clavicle bone defect. If multiple matchstick-shaped bone grafts are needed in the bone graft site, the whole cylindrical bone can also be divided into multiple matchstick-shaped small bones along the tangent line cut by the blades. The size and shape of the bone graft can be selected according to the actual situation during the operation, and the operation can be flexibly adjusted. The bone taking device 21 can be inserted into the bone cortex surface through a small incision, and the size of the incision can be controlled within 1.5 cm, while the traditional bone taking method usually needs an incision of more than 3 cm, which significantly reduces the incision compared with the traditional method, achieves the effect of minimally invasive, and reduces the incidence of wound-related complications at the bone taking site after the operation.

[0036] The use process of the embodiment: taking the most commonly used iliac bone site as an example, the sampling handle 12 is adjusted so that the baffle 13 is located at a proper height to determine the bone taking depth, a cut of about 1.5 cm is made at the anterior superior iliac spine, the skin, subcutaneous tissue, fascia and periosteum are successively incised, the bone taking device is vertically inserted, the front end is firmly placed on the bone cortex, the handle 32 is slowly deepened by hammering, until the baffle 13 reaches the bone cortex, the handle 32 is rotated to disconnect the bone graft in the bone taking device, and then the tool is withdrawn. The incision is washed, and after sufficient hemostasis, the incision is closed. The handle 32 is rotated clockwise to push out the bone graft in the bone taking device. The soft tissue on the cortical bone is scraped off, and then the bone graft is implanted into the bone graft site after adjusting the shape of the bone graft according to the needs of the bone graft site.

[0037] Embodiment 2

[0038] Referring to the accompanying drawings Figures 3-6 As shown in the drawings, in order to solve the problem of lack of special tools for taking vertebral body bone tissue in clinic, combined with clinical experience, the embodiment provides a tool which can be percutaneously punctured into the vertebral body, and a mosquito coil-shaped spiral structure is formed in front of the working sleeve by adjusting the depth of the inner core wire, so as to prevent the bone tissue in the sleeve from retreating and ensure the success rate of biopsy. The tool is simple and easy to operate, and is suitable for pathological tissue biopsy of vertebral body and other cancellous bone lesions. In the embodiment, the sleeve assembly 3 comprises a T-shaped working sleeve 34, a pipeline 35 is arranged in the T-shaped working sleeve 34 in the vertical direction, a C-shaped pipeline 36 is arranged at the bottom of the T-shaped working sleeve 34, and the pipeline 35 and the C-shaped pipeline 36 are in communication with each other. The cutting assembly 2 comprises a mosquito coil-shaped wire inner core 23, and the sampling member is a wire inner core 14. The wire inner core 14 extends into the pipeline 35 and is twisted into the mosquito coil-shaped wire inner core 23 at the C-shaped pipeline 36. The operator inserts the wire inner core 14 from above the working sleeve 34 to the bottom end of the sleeve 35. At this time, the wire inner core 14 is continuously inserted. Since the wire inner core 14 has been pre-shaped, it will be punched out in the form of a “mosquito coil” disc at the bottom of the T-shaped working sleeve 34 and shuttle in the bone, forming a spiral disc structure, cutting bone tissue, and finally pulling out the T-shaped working sleeve 34. The bone tissue left in the T-shaped working sleeve 34 is stored in the sleeve by the disc structure of the wire inner core 14, and is not easy to lose. After the device is moved to the outside of the body, the wire inner core 14 is pulled out, the biopsy bone tissue is removed, and the operation is completed. The embodiment can pass through the inner diameter of the working channel of the vertebral body strengthening device or directly use the T-shaped working sleeve 34 to puncture, so as to realize percutaneous minimally invasive operation. The working sleeve is designed in the form of T, which is convenient for knocking into or out of the working sleeve with a hammer, and is also convenient for manual rotation operation. The pipeline 35 and the C-shaped pipeline 36 at the bottom end are designed inside the embodiment, which is convenient for inserting and pulling out the special wire inner core 14 which has been pre-shaped. The C-shaped pipeline 36 and the pre-shaped wire inner core 14 have the same curvature, which is convenient for forming the mosquito coil-shaped wire inner core 23. Meanwhile, the ring-shaped hand handle 15 is designed on the wire inner core 14, which is convenient for inserting and pulling out the wire inner core 14. The wire inner core 14 is designed with a scale, which is convenient for observing the depth of the wire inner core 14 inserted in front of the working sleeve.

[0039] The use process of the embodiment is as follows: the working sleeve of vertebral body strengthening surgery, i.e. vertebral body formation or kyphoplasty, is established, or the T-shaped working sleeve 34 is directly hammered into the working sleeve, the bottom of the sleeve is observed under fluoroscopy to reach the vertebral body lesion, the pre-shaped wire inner core 14 is inserted, the depth scale of the wire inner core 14 is observed at all times, and whether the front edge of the wire forms a disc structure according to the plan is observed under fluoroscopy. When the disc structure is formed, the working sleeve is knocked out, the wire inner core 14 is pulled out, the pathological tissue is removed, and the pathological tissue is sent for pathological detection.

[0040] Embodiment 3

[0041] Referring to the drawings Figure 7 and the drawings Figure 8 As shown in the drawings, in the embodiment, according to the most commonly used transpedicular vertebral body biopsy method in the clinic, it is designed from top to bottom into a T-shaped rotating handle 4, an oval straight cylinder 5. The oval straight cylinder 5 is designed to better separate the tissue in the cylinder when the rotating handle is rotated. The oval straight cylinder 5 has a 1cm high septum 6 at the distal end, which divides the oval straight cylinder 5 at the distal end into two parts. The septum 6 can better cut the bone tissue in the vertebral body when it is deepened, and can better separate the tissue in the cylinder when the rotating handle is rotated. The distal edge 7 of the oval straight cylinder 5 is also serrated, which can help the device better cut the bone tissue in the vertebral body when it is deepened.

[0042] The use process of the embodiment: after establishing a working channel through percutaneous pedicle puncture, a working sleeve is placed, and the device is placed in the working sleeve. A hammer is used to strike the T-shaped handle to slowly deepen the device. When the front end of the device reaches the appropriate position in the vertebral body, or when a significant resistance to deepening is felt, the T-shaped rotating handle 4 is rotated by 270°, so that the tissue in the cylinder and the tissue outside the cylinder are separated. At this time, the front septum is perpendicular to the starting puncture, and the T-shaped rotating handle 4 is lifted to retreat the device to obtain the pathological sample.

[0043] The above description of the disclosed embodiments enables a person skilled in the art to implement or use the present application. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application will not be limited to these embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A minimally invasive device for biopsy of bone tissue, comprising: The sampling assembly, the cutting assembly and the sleeve assembly, the sampling assembly comprises a sampling piece and a sampling handle installed on the sampling piece, the sleeve assembly comprises a sleeve arranged in vertical direction and a handle arranged in horizontal direction, the handle is installed on the top of the sleeve, the sampling piece extends into the sleeve, the cutting assembly is installed on the bottom of the sleeve and connected with the sampling piece.

2. A minimally invasive device for biopsy of bone tissue according to claim 1, wherein, The inner wall of the sleeve is provided with a threaded part.

3. A minimally invasive device for biopsy of bone tissue according to claim 2, wherein, The cutting assembly comprises a cylindrical bone extractor, the wall thickness of the bone extractor decreases from top to bottom, a plurality of bone knives are sequentially installed on the inner wall of the bone extractor in circumferential direction, the bone knives are arranged perpendicularly to the inner wall of the bone extractor, the bone extractor is connected with the bottom of the sleeve and communicates with the sleeve.

4. A minimally invasive device for biopsy of bone tissue according to claim 3, wherein, A baffle is installed on the end of the sampling piece away from the sampling handle, the sampling piece and the baffle both extend into the sleeve, the sampling piece is threadedly connected with the inner wall of the sleeve through the threaded part, the sampling piece moves up and down when rotating, the baffle changes position driven by the sampling piece, when the sampling piece rotates to the top of the threaded part, the baffle is located at the top of the bone extractor, when the sampling piece rotates to the bottom of the threaded part, the baffle is located at the bottom of the bone extractor.

5. A minimally invasive device for biopsy of osseous tissue according to claim 4, wherein, When the sampling piece rotates clockwise, the baffle descends, when the sampling piece rotates counterclockwise, the baffle ascends.

6. A minimally invasive device for biopsy of osseous tissue according to claim 1, wherein, The cutting surface of the handle is inverted triangular.

7. A minimally invasive device for biopsy of osseous tissue according to claim 1, wherein, A pipe is arranged in vertical direction inside the sleeve, a C-shaped pipe is arranged at the bottom of the sleeve, the pipe communicates with the C-shaped pipe, the cutting assembly comprises a mosquito coil-shaped steel inner core, the sampling piece is a steel inner core, the steel inner core extends into the pipe to the C-shaped pipe to rotate into the mosquito coil-shaped steel inner core.

8. A minimally invasive device for biopsy of osseous tissue according to claim 1, wherein, The cutting surface of the handle in horizontal direction is elliptical.

9. A minimally invasive device for biopsy of osseous tissue according to claim 8, wherein, The cutting assembly comprises a serrated septum, the serrated septum is installed on the bottom of the sleeve, the serrated septum divides the bottom of the sleeve into two parts.

10. The bone tissue biopsy micro-wound device of claim 8, wherein, The edge of the bottom of the sleeve is serrated.

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