Elisa plate bracket capable of uniformly controlling temperature

By designing a uniformly temperature-controlled ELISA plate holder and utilizing a water circulation system and a limiting device, the problem of insufficient temperature control during the reaction process of the ELISA plate was solved, thereby improving the reaction rate and maintaining the stability of the ELISA plate.

CN223517572UActive Publication Date: 2025-11-07CHINA AGRI VET BIO SCI & TECH
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Patent Information

Application Number
CN202422970536.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-11-07
Estimated Expiration
2034-12-03

AI Technical Summary

Technical Problem

Common ELISA plates lack temperature control during the reaction process, resulting in a low reaction rate.

Method used

A uniformly temperature-controlled ELISA plate holder was designed. Temperature regulation is achieved through a water circulation system in the upper and lower heating boxes. Hot water is used to heat the liquid in the upper heating box, and a limiting device is used to maintain the stability of the ELISA plate.

Benefits of technology

Uniform temperature control was achieved during the reaction process of the ELISA plate, which improved the reaction rate and maintained the stability of the ELISA plate.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides an elisa plate support with uniform temperature control, which relates to the technical field of veterinary vaccine production devices and comprises a support plate, a hole groove is arranged on the upper surface of the support plate, a batten is arranged in the hole groove, a heating device is arranged below the support plate and comprises an upper heating box and a lower heating box, and the upper heating box is connected with the lower heating box. The supporting plate is located at the top end of the upper heating box, a first water inlet pipe and a first water outlet pipe are arranged on the bottom face of the upper heating box, and the first water inlet pipe and the first water outlet pipe penetrate through the lower heating box. According to the elisa plate bracket capable of uniformly controlling the temperature, purified water is injected into the upper heating box, hot water is injected into the lower heating box, the upper heating box is heated by the hot water in the lower heating box, and the temperature of the upper heating box is uniformly regulated and controlled by adjusting the temperature of the water injected into the lower heating box; and uniform temperature control on the elisa plate is realized when the reaction reagent reacts on the elisa plate.
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Description

TECHNICAL FIELD

[0001] The utility model relates to a kind of enzyme label plate support, specifically a kind of enzyme label plate support of uniform temperature control, belong to veterinary vaccine production device technical field. BACKGROUND

[0002] Veterinary vaccine in the process of production, usually adopt enzyme label plate for enzyme-linked immunosorbent assay, the purity, concentration and proportion of antigen, antibody, labeled antibody or antigen involved in immunology reaction, buffer type, concentration and ionic strength, pH value and reaction temperature, time and so on Condition plays a key role, enzyme label plate also plays an indispensable role in bacterial endotoxin test, in bacterial endotoxin test, enzyme label plate as a container for reaction of limulus reagent and sample, participates in the whole process of bacterial endotoxin test and affects its test results.

[0003] Common enzyme label plate is placed on platform after placing reaction reagent, since limulus reagent and sample reaction process needs strict temperature and time control, when limulus reagent is added into endotoxin and sample mixture, reaction has started, and in certain temperature range, the higher the reaction temperature, the greater the reaction rate, so enzyme label plate needs uniform temperature control when using, however, common enzyme label plate does not have temperature control capability, thus leading to its reaction rate is lower.

[0004] Therefore, a kind of enzyme label plate support of uniform temperature control is proposed. UTILITY MODEL CONTENT

[0005] The utility model proposes a kind of enzyme label plate support of uniform temperature control to realize that reaction reagent is reacted on enzyme label plate to enzyme label plate is uniformly temperature controlled.

[0006] The utility model is realized by the following technical scheme: a kind of enzyme label plate support of uniform temperature control, including support plate, the upper surface of the support plate is equipped with hole slot, the inside of the hole slot is provided with batten, the lower of the support plate is provided with heating device, the heating device includes upper heating box and lower heating box, the support plate is located at the top of upper heating box, the bottom surface of the upper heating box is equipped with first water inlet pipe and first water outlet pipe, the first water inlet pipe and first water outlet pipe are through lower heating box, the first water inlet pipe and first water outlet pipe are all connected with the water pump of outside, the side of the lower heating box is fixedly connected with second water inlet pipe and second water outlet pipe, the second water inlet pipe and second water outlet pipe are all connected with the water pump of outside.

[0007] The upper surface of the support plate is provided with a plurality of first limiting devices, the first limiting device includes the first box body fixed on the upper surface of support plate, the inner wall of the first box body is slidably connected with first sliding block, the upper surface of the first box body is equipped with notch, the upper surface of the first sliding block is fixed with first adjusting plate.

[0008] Further, the inner wall of the first box body is fixed with a first reset spring and a first reset telescopic rod, one end of the first reset spring and the first reset telescopic rod is fixed with the first sliding block, and the board is limited through the first sliding block.

[0009] The side of the upper heating box is provided with a second limiting device, the second limiting device comprises a second box body fixed to the outer side of the upper heating box, a second sliding block is slidably connected to the inner wall of the second box body, and a groove is formed in the upper surface of the second box body, and a second adjusting plate is fixed to the upper surface of the second sliding block.

[0010] Further, the inner wall of the second box body is fixed with a second reset spring, and the other end of the second reset spring is fixed with the second sliding block, so that the supporting plate is limited through the second sliding block.

[0011] The test tube on the board extends into the inside of the upper heating box, and the bottom end of the test tube on the board does not contact the inner bottom wall of the upper heating box.

[0012] The inner wall of the lower heating box is provided with a groove, and the upper heating box and the lower heating box are sealed, hot water is injected into the lower heating box, the hot water in the lower heating box heats the liquid in the inside of the upper heating box, and then the temperature of the liquid in the upper heating box is increased.

[0013] The utility model provides a kind of enzyme mark plate support of uniform temperature control, it has the beneficial effect as follows:

[0014] 1, the enzyme mark plate support of uniform temperature control, injects pure water into upper heating box, injects hot water into lower heating box, heats upper heating box by hot water in lower heating box, by adjusting the temperature of water injected into lower heating box, and then the temperature of upper heating box is uniformly regulated, realizes the uniform temperature control of enzyme mark plate when reaction reagent is reacted in enzyme mark plate.

[0015] 2, the enzyme mark plate support of uniform temperature control, the board is limited by first sliding block, avoid the board to rise and separate from supporting plate due to buoyancy, supporting plate is limited by second sliding block, avoid the stability of supporting plate to be influenced by the buoyancy of board, maintain the stability of board and supporting plate in reaction process. ACCURACY OF DRAWINGS

[0016] Figure 1 It is the three-dimensional structure schematic diagram of the utility model;

[0017] Figure 2 It is the sectional view of lower heating box side view of the utility model;

[0018] Figure 3 It is the utility model Figure 2Structure schematic view of the upper heating box;

[0019] Figure 4 The utility model discloses a heating box side view's section view

[0020] Figure 5 The utility model discloses Figure 4 Structure schematic view of the middle B.

[0021] Mark explanation

[0022] 1, support plate;2, batten;

[0023] 3, heating device;301, upper heating box;302, lower heating box;303, first water inlet pipe;304, first water outlet pipe;305, second water inlet pipe;306, second water outlet pipe;

[0024] 4, first limiting device;401, first box body;402, first sliding block;403, first adjusting plate;404, first reset spring;405, first reset telescopic rod;

[0025] 5, second limiting device;501, second box body;502, second sliding block;503, second adjusting plate;504, second reset spring. Specific implementation

[0026] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the present application.

[0027] Please refer to Figures 1-5 The utility model discloses a kind of enzyme label plate support of uniform temperature control, including support plate 1, the upper surface of support plate 1 is set with hole slot, the inside of hole slot is provided with batten 2, heating device 3 is provided in the lower of support plate 1, heating device 3 includes upper heating box 301 and lower heating box 302, support plate 1 is located in the top of upper heating box 301, the bottom surface of upper heating box 301 is set with first water inlet pipe 303 and first water outlet pipe 304, first water inlet pipe 303 and first water outlet pipe 304 are through lower heating box 302, first water inlet pipe 303 and first water outlet pipe 304 are connected with the water pump of outside communication, second water inlet pipe 305 and second water outlet pipe 306 are fixedly communicated with the side of lower heating box 302, second water inlet pipe 305 and second water outlet pipe 306 are connected with the water pump of outside communication.

[0028] Please refer to Figure 1 、 Figure 2 andFigure 3 The upper surface of the support plate 1 is provided with a plurality of first limiting devices 4, the first limiting device 4 comprises a first box body 401 fixed on the upper surface of the support plate 1, the inner wall of the first box body 401 is slidably connected with a first sliding block 402, the upper surface of the first box body 401 is provided with a notch, the upper surface of the first sliding block 402 is fixedly connected with a first adjusting plate 403, the inner wall of the first box body 401 is fixedly connected with a first reset spring 404 and a first reset telescopic rod 405, the other end of the first reset spring 404 and the first reset telescopic rod 405 is fixedly connected with the first sliding block 402, and the first sliding block 402 is used for limiting the batten 2.

[0029] Please refer to Figure 1 , Figure 4 and Figure 5 , the side surface of the upper heating box 301 is provided with a second limiting device 5, the second limiting device 5 comprises a second box body 501 fixed on the outer side surface of the upper heating box 301, the inner wall of the second box body 501 is slidably connected with a second sliding block 502, the upper surface of the second box body 501 is provided with a notch, the upper surface of the second sliding block 502 is fixedly connected with a second adjusting plate 503, the inner wall of the second box body 501 is fixedly connected with a second reset spring 504, the other end of the second reset spring 504 is fixedly connected with the second sliding block 502, and the second sliding block 502 is used for limiting the support plate 1.

[0030] Please refer to Figure 1 , Figure 2 and Figure 4 , the test tube on the batten 2 extends into the inside of the upper heating box 301, the bottom end of the test tube on the batten 2 does not contact the inner bottom wall of the upper heating box 301, the inner wall of the lower heating box 302 is provided with a groove, the upper heating box 301 and the lower heating box 302 are sealed, hot water is injected into the lower heating box 302, the hot water in the lower heating box 302 heats the liquid in the inside of the upper heating box 301, and then the temperature of the liquid in the upper heating box 301 is increased.

[0031] When the utility model is used: pure water is injected into the upper heating box 301, hot water is injected into the lower heating box 302, the hot water in the lower heating box 302 heats the upper heating box 301, the temperature of the water injected into the lower heating box 302 is adjusted, and then the temperature of the upper heating box 301 is uniformly regulated, and the enzyme standard plate is uniformly temperature-controlled when the reaction reagent is reacted on the enzyme standard plate.

[0032] The first sliding block 402 is used for limiting the batten 2, the batten 2 is prevented from being separated from the support plate 1 due to buoyancy, the second sliding block 502 is used for limiting the support plate 1, the stability of the support plate 1 is prevented from being affected by the buoyancy caused by the batten 2, and the stability of the batten 2 and the support plate 1 in the reaction process is maintained.

[0033] The basic principle and main features of the present application and the advantages of the present application are shown and described above. Those skilled in the art should understand that the present application is not limited by the above examples, and the above examples and descriptions in the specification are only to illustrate the principles of the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A uniform temperature controlled enzyme plate support comprising a support plate (1), characterized in that: The upper surface of the support plate (1) is provided with a hole groove, the inside of the hole groove is provided with a batten (2), the lower part of the support plate (1) is provided with a heating device (3), the heating device (3) comprises an upper heating box (301) and a lower heating box (302), the support plate (1) is located at the top end of the upper heating box (301), the bottom surface of the upper heating box (301) is provided with a first water inlet pipe (303) and a first water outlet pipe (304), the first water inlet pipe (303) and the first water outlet pipe (304) penetrate the lower heating box (302), the first water inlet pipe (303) and the first water outlet pipe (304) are connected with the water pump outside, the side of the lower heating box (302) is fixedly connected with a second water inlet pipe (305) and a second water outlet pipe (306), the second water inlet pipe (305) and the second water outlet pipe (306) are connected with the water pump outside.

2. The uniform temperature-controlled enzyme microplate holder of claim 1, wherein: The upper surface of the support plate (1) is provided with a plurality of first limiting devices (4), the first limiting device (4) comprises a first box body (401) fixed on the upper surface of the support plate (1), the inner wall of the first box body (401) is slidably connected with a first sliding block (402), the upper surface of the first box body (401) is provided with a notch, and the upper surface of the first sliding block (402) is fixedly connected with a first adjusting plate (403).

3. The uniform temperature-controlled microplate holder of claim 2, wherein: The inner wall of the first box body (401) is fixedly connected with a first reset spring (404) and a first reset telescopic rod (405), and the other end of the first reset spring (404) and the first reset telescopic rod (405) is fixedly connected with the first sliding block (402).

4. The uniform temperature controlled microplate holder of claim 1, wherein: The side of the upper heating box (301) is provided with a second limiting device (5), the second limiting device (5) comprises a second box body (501) fixed on the outer side of the upper heating box (301), the inner wall of the second box body (501) is slidably connected with a second sliding block (502), the upper surface of the second box body (501) is provided with a notch, and the upper surface of the second sliding block (502) is fixedly connected with a second adjusting plate (503).

5. The uniform temperature controlled microplate holder of claim 4, wherein: The inner wall of the second box body (501) is fixedly connected with a second reset spring (504), and the other end of the second reset spring (504) is fixedly connected with the second sliding block (502).

6. The uniform temperature controlled microplate holder of claim 1, wherein: The test tube on the batten (2) extends into the inside of the upper heating box (301), and the bottom end of the test tube on the batten (2) is not in contact with the inner bottom wall of the upper heating box (301).

7. The uniform temperature controlled microplate holder of claim 1, wherein: The inner wall of the lower heating box (302) is provided with a groove, and the upper heating box (301) and the lower heating box (302) are sealed.