Multi-cavity hematopoietic stem cell culture device

Abstract

The utility model provides a multi-cavity hematopoietic stem cell culture device, and belongs to the technical field of medical equipment. Comprising a main body, a culture plate is arranged outside the main body, a plurality of grips are slidably connected to the top end of the main body, and a translation assembly is arranged between the main body and the culture plate; the clamping assembly is used for fixing the relative position between the main body and the culture plate, and the clamping assembly is connected with the translation assembly; the placing assembly is used for placing an external identification label, and the placing assembly is fixedly connected to the periphery of the top of the main body; and the sealing assembly is used for sealing the top end of the placing assembly, and the sealing assembly is connected with the translation assembly through a connecting rod. By utilizing the combination of the fixed seat, the elastic sheet and the top blocks, when the culture plate moves to a proper position, the top blocks are clamped into the clamping grooves in the two sides of the culture plate through the elastic force of the elastic sheet, so that the culture plate is stably fixed, shaking in the carrying or transporting process is avoided, and the safety of a cell sample is ensured.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical equipment technical field especially relates to a multi -chamber formula hematopoietic stem cell culture device. BACKGROUND

[0002] Hematopoietic stem cell culture device is the equipment for cultivating and amplifying hematopoietic stem cell, these devices usually integrate multiple functions and technologies to ensure the stable growth and proliferation of hematopoietic stem cell in vitro environment.

[0003] But in actual work, through the recess to place the culture plate, and the culture plate lacks the fixed structure, when moving the placing rack, the culture plate is easy to shake, so that the cell sample is easy to shake out of the culture dish, and the control cell sample of detection is replaced every time, and the identification sign needs to be pasted and pulled down frequently, so that the replacement steps are complicated, and the work efficiency is reduced, therefore, the utility model provides a multi -chamber formula hematopoietic stem cell culture device to meet the needs. UTILITY MODEL CONTENTS

[0004] To solve the above technical problems, the utility model provides the following technical scheme:

[0005] A multi -chamber formula hematopoietic stem cell culture device, including the main part, the outside of main part is equipped with culture plate, the top of main part is connected with a plurality of handles slidingly, and the translation assembly is equipped between main part and culture plate;Clamping assembly is used for the relative position fixation between main part and culture plate, and clamping assembly is connected with translation assembly;Place assembly is used for placing external identification sign, and place assembly is fixedly connected to the periphery of the top of main part;Sealing assembly is used for sealing the top of place assembly, and sealing assembly is connected with translation assembly through connecting rod.

[0006] Optionally, the translation assembly includes a moving rod, both ends of the bottom of the moving rod are fixedly connected with a fixed rod, and the bottom of the fixed rod is fixedly connected with a limiting block.

[0007] Optionally, the clamping assembly includes a fixed seat, one side of the bottom end of the corresponding fixed rod is fixedly connected with the fixed seat, the other side of the fixed seat is fixedly connected with a plurality of elastic sheets, the other end of the elastic sheet is fixedly connected with a top block, a plurality of weakening grooves are formed in the outside of the elastic sheet, and a guide rail is fixedly installed on the outside of the elastic sheet.

[0008] Optionally, the place assembly includes a box body fixedly connected to the top of the main part, and a sliding groove, an extrusion groove and a taking groove are formed in the inside of the box body respectively.

[0009] Optionally, springs are fixedly connected around the inside cavity of the box body, and the top of the spring is fixedly connected with a lifting plate.

[0010] Optionally, the sealing assembly comprises a baffle, both ends of the baffle are fixedly connected with a side strip, and both ends of the bottom of the baffle are fixedly connected with a pressing plate.

[0011] Optionally, the culture plate is clamped with a plurality of culture dishes, a clamping groove is formed on both sides of the culture plate, and a plurality of guide grooves are formed on the inside of the culture plate outside the clamping groove.

[0012] Compared with the prior art, the utility model has at least the following beneficial effects:

[0013] In the above scheme, the cooperation of the moving rod and the fixed rod allows the culture plate to move horizontally above the main body, facilitates the adjustment of the position of the culture plate, and facilitates user operation. At the same time, the design of the limiting block can prevent the culture plate from moving excessively or falling off.

[0014] In the above scheme, the combination of the fixed seat, the elastic sheet and the top block is used, when the culture plate is moved to the appropriate position, the top block is clamped into the clamping groove on both sides of the culture plate through the elastic force of the elastic sheet, the stable fixation of the culture plate is realized, the shaking in the process of moving or transporting is avoided, and the safety of the cell sample is ensured.

[0015] In the above scheme, the box body is designed with a plurality of groove positions for placing and fixing external identification tags, which facilitates users to replace and check the cell sample information at any time without frequent pasting and tearing of the identification tags, and improves the work efficiency. At the same time, the combination of the spring and the lifting plate enables the identification tag to be stably fixed in the box body, avoiding falling.

[0016] In the above scheme, the baffle is connected with the connecting rod through the side strip and moves with the movement of the translation assembly. When the culture plate is moved to the working position and fixed, the baffle is lowered, the box body top is pressed by the pressing plate, the sealing effect is realized, the external pollution is prevented from entering the culture environment, and the culture quality is ensured. BRIEF DESCRIPTION OF DRAWINGS

[0017] The drawings incorporated herein and forming part of the specification show embodiments of the utility model, and together with the specification further serve to explain the principles of the utility model, and enable a person skilled in the relevant art to implement and use the utility model.

[0018] Figure 1 It is a schematic view of a three-dimensional assembly of a multi-cavity hematopoietic stem cell culture device;

[0019] Figure 2 It is a schematic view of the connection structure of the translation assembly;

[0020] Figure 3 It is a schematic view of the connection structure of the placement assembly;

[0021] Figure 4 Fig. 1 is a schematic view of the connecting structure of the spring;

[0022] Figure 5 Fig. 2 is a partial sectional view of the main body;

[0023] Figure 6 Fig. 3 is a schematic view of the clamping assembly in perspective.

[0024] [Reference signs]

[0025] 1, main body; 2, translation assembly; 201, moving rod; 202, fixed rod; 203, limiting block; 3, culture plate; 4, clamping assembly; 401, fixed seat; 402, elastic sheet; 403, top block; 404, weakening groove; 405, guide rail; 5, sealing assembly; 501, baffle; 502, edge strip; 503, pressing plate; 6, placing assembly; 601, box body; 602, sliding groove; 603, extrusion groove; 604, taking groove; 7, spring; 8, lifting plate; 9, clamping groove; 10, handle.

[0026] As shown in the drawings, in order to clearly realize the components of the embodiments of the present application, specific components and devices are marked in the drawings, but this is only for the need of illustration, and is not intended to limit the present application in the specific components, devices and environment, and according to the specific needs, those skilled in the art can adjust or modify these devices and environment. DETAILED DESCRIPTION

[0027] A multi-cavity hematopoietic stem cell culture device provided by the present application is described in detail below in combination with the drawings and specific embodiments. It is explained here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments, and other alternative ways can also be used by those skilled in the art to implement some known technologies; and the drawings are only used to more specifically describe the embodiments, and are not intended to specifically limit the present application.

[0028] As Figures 1 to 6As shown, the utility model discloses a multi -cavity formula hematopoietic stem cell culture device, including main part 1, the outside of main part 1 is equipped with culture plate 3, the top of main part 1 is slidably connected with a plurality of handles 10, and the translation assembly 2 is arranged between main part 1 and culture plate 3, the translation assembly 2 includes shift rod 201, both ends of the bottom of shift rod 201 are fixedly connected with fixed rod 202, the bottom of fixed rod 202 is fixedly connected with limit block 203, the periphery of the inner chamber of box body 601 is fixedly connected with spring 7, the top of spring 7 is fixedly connected with lifting plate 8, a plurality of culture dishes are clamped in the inside of culture plate 3, the both sides of culture plate 3 are provided with clamping groove 9, a plurality of guide grooves are arranged in the outside of clamping groove 9 in the inside of culture plate 3, the user holds handle 10, moves shift rod 201 along the slide rail of the top of main part 1, shift rod 201 drives fixed rod 202 and limit block 203 to move together, thereby drive whole culture plate 3 to move in horizontal direction, limit block 203 prevents culture plate 3 from excessively deviating or falling off during the movement, provides flexible adjustment mode, is convenient for user to move culture plate 3 to the appropriate position according to the need, improves the convenience and security of operation, reduces the risk of cell sample loss due to improper movement;

[0029] In the embodiment, as shown in the figure, Figures 1 to 6 The clamping assembly 4 is used for fixing the relative position between the main body 1 and the culture plate 3, and is connected with the translation assembly 2. The clamping assembly 4 includes a fixed seat 401, which is fixedly connected to one side of the bottom end of the corresponding fixed rod 202. The other side of the fixed seat 401 is fixedly connected with a plurality of elastic sheets 402. The other end of the elastic sheet 402 is fixedly connected with a top block 403. A plurality of weakening grooves 404 are arranged on the outside of the elastic sheet 402. A guide rail 405 is fixedly installed on the outside of the elastic sheet 402. When the culture plate 3 moves to the specified position, the clamping groove 9 is aligned with the elastic sheet 402 and the top block 403 on the fixed seat 401. The elastic sheet 402 is pushed to enter the clamping groove 9 under the action of its own elastic force, thereby fixing the culture plate 3. The weakening grooves 404 increase the elasticity of the elastic sheet 402, so that the clamping process is more smooth. The guide rail 405 helps the top block 403 to accurately enter the clamping groove 9, realizes the quick and stable fixation of the culture plate 3, prevents shaking during moving or transporting, improves the safety and stability of the culture process, and guarantees the culture quality of hematopoietic stem cells.

[0030] In the embodiment, as shown in the figure, Figures 1 to 6As shown, the placement component 6 is used to place external labels. The placement component 6 is fixedly connected to the top of the main body 1 around the perimeter. The placement component 6 includes a box 601 fixedly connected to the top of the main body 1. The box 601 has a sliding groove 602, a squeezing groove 603 and a picking groove 604 respectively. The user places the external label in the sliding groove 602 in the box 601. The label is stably fixed by the action of the spring 7 and the lifting plate 8. When it is necessary to replace or view the label, the user can easily complete the operation through the squeezing groove 603 and the picking groove 604. This provides a convenient label management method, reduces the tedious steps caused by frequent pasting and tearing of labels, improves work efficiency, and avoids the risk of cell sample confusion caused by label falling off or being damaged.

[0031] In this embodiment, as Figures 1 to 6 As shown, the sealing component 5 is used to seal the top of the placement component 6. The sealing component 5 is connected to the translation component 2 via a connecting rod. The sealing component 5 includes a baffle 501, with side strips 502 fixedly connected to both ends of the baffle 501. Pressure plates 503 are fixedly connected to both ends of the bottom of the baffle 501. When the culture plate 3 is fixed in place, the sealing component 5 descends with the movement of the translation component 2. The pressure plates 503 at the bottom of the baffle 501 contact the top of the box 601 and apply pressure to achieve a sealing effect. The side strips 502 provide additional stability and sealing, ensuring the sealing of the top of the placement component 6, preventing external contaminants from entering the culture environment, ensuring the sterility and safety of the hematopoietic stem cell culture process, and improving the culture success rate.

[0032] The utility model discloses a working principle, the user holds the handle 10, and along the slide rail of main part 1 top end moves the shift bar 201. The shift bar 201 drives fixed link 202 and limit block 203 together and move, to drive the culture plate 3 to move to the predetermined working position in horizontal direction, and limit block 203 prevents culture plate 3 from excessive deviation or falling off in the moving process, when culture plate 3 moves to the designated position, the clamping groove 9 is aligned with the spring 402 and the top block 403 on the fixed seat 401. The spring 402 is under the action of self elasticity, and the top block 403 is pushed into the clamping groove 9, to fix culture plate 3. This process is completed by the clamping assembly 4, ensures that culture plate 3 does not shake in the culture process, and the temperature and humidity in the culture environment are monitored by the built-in temperature and humidity sensor of the device, and are automatically adjusted to the range suitable for the growth of hematopoietic stem cells, if necessary, can start the humidification or heating / cooling system, ensures that the culture environment is stable, after culture plate 3 is fixed in place, the sealing assembly 5 is lowered along with the movement of the translation assembly 2. The pressing plate 503 at the bottom of the baffle 501 contacts the top of the box body 601 and exerts pressure, realizes the sealing effect, prevents external pollutants from entering the culture environment, after confirming that all settings are correct, start the culture device, and begin the in-vitro culture process of hematopoietic stem cells. According to the culture requirements, set appropriate culture time, culture conditions and other parameters, regularly check the temperature and humidity of the culture environment, the state of the culture medium and the growth of hematopoietic stem cells during the culture process, and if abnormal conditions are found, timely processing, such as adjusting the culture conditions, replacing the culture medium, etc., record the key data during the culture process, such as culture time, culture condition change, growth curve of hematopoietic stem cells, etc., for subsequent analysis and summary, according to the identification label, manage different batches of hematopoietic stem cell samples, and ensure the accuracy and traceability of the samples.

[0033] The utility model covers any alternative, modification, equivalent method and scheme on the essence and range of the utility model. In order to make the public have the thorough understanding of the utility model, the specific details are explained in the following preferred embodiments of the utility model, and the utility model can also be completely understood without the description of these details for the person skilled in the art. In addition, in order to avoid unnecessary confusion to the essence of the utility model, the well-known method, process, flow, element and circuit etc. are not explained in detail.

[0034] The above only is the preferred implementation mode of the utility model, should point out, for ordinary skill in the art of the prior art, on the premise of not departing from the principle of the utility model, still can make a number of improvements and refinements, these improvements and refinements also should view as the protection range of the utility model.

Claims

1. A multi-cavity hematopoietic stem cell culture device comprising a main body (1), characterized in that, The outside of the main body (1) is provided with a culture plate (3), the top end of the main body (1) is slidably connected with a plurality of handles (10), and the main body (1) and the culture plate (3) are provided with a translation assembly (2); The clamping assembly (4) is used for fixing the relative position between the main body (1) and the culture plate (3), and the clamping assembly (4) is connected with the translation assembly (2); The placing assembly (6) is used for placing an external identification sign, and the placing assembly (6) is fixedly connected to the periphery of the top of the main body (1); The sealing assembly (5) is used for sealing the top end of the placing assembly (6), and the sealing assembly (5) is connected with the translation assembly (2) through a connecting rod.

2. The multi-cavity hematopoietic stem cell culture device of claim 1, wherein, The translation assembly (2) comprises a moving rod (201), both ends of the bottom of the moving rod (201) are fixedly connected with a fixed rod (202), and the bottom of the fixed rod (202) is fixedly connected with a limiting block (203).

3. The multi-cavity hematopoietic stem cell culture device of claim 2, wherein, The clamping assembly (4) comprises a fixed seat (401), one side of the bottom of the corresponding fixed rod (202) is fixedly connected with the fixed seat (401), the other side of the fixed seat (401) is fixedly connected with a plurality of elastic sheets (402), the other end of the elastic sheet (402) is fixedly connected with a top block (403), a plurality of weakening grooves (404) are formed in the outside of the elastic sheet (402), and a guide rail (405) is fixedly installed outside the elastic sheet (402).

4. The multi-cavities hematopoietic stem cell culture device according to claim 1, wherein, The placing assembly (6) comprises a box body (601) fixedly connected to the top of the main body (1), and a sliding groove (602), a pressing groove (603) and a taking groove (604) are formed in the inside of the box body (601) respectively.

5. The multi-cavity hematopoietic stem cell culture device of claim 4, wherein, The inside of the box body (601) is fixedly connected with a spring (7), and the top of the spring (7) is fixedly connected with a lifting plate (8).

6. The multi-cavities hematopoietic stem cell culture device of claim 1, wherein, The sealing assembly (5) comprises a baffle (501), both ends of the baffle (501) are fixedly connected with a side strip (502), and both ends of the bottom of the baffle (501) are fixedly connected with a pressing plate (503).

7. The multi-cavities hematopoietic stem cell culture device of claim 1, wherein, The inside of the culture plate (3) is clamped with a plurality of culture dishes, the two sides of the culture plate (3) are provided with clamping grooves (9), and a plurality of guide grooves are formed in the inside of the culture plate (3) and outside the clamping grooves (9).

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