Seal ring of chromatographic column

Abstract

The utility model belongs to the technical field of liquid chromatography, and particularly relates to a sealing ring of a chromatographic column, which comprises a first handle seat, a central rod, a screw rod, a second handle seat, an upper flange, a column head, a column casing, a lower end cover, a column head pressing ring, a distributor, a support sealing ring, a sealing ring, a column head pressing ring flange, an inclined plane, a distributor flange and a lip edge, the column head penetrates through the upper flange and extends into the column casing, the upper surface of the column head is connected with a screw rod, the upper surface of the screw rod is provided with a first handle seat, the center of the screw rod is provided with a center rod capable of moving up and down, the bottom of the screw rod is fixedly connected with a distributor, and the column head pressing ring penetrates through the screw rod and is arranged on the outer side of the distributor in a sleeving mode. The sealing device is simple in structure and reliable in sealing.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatography technology, specifically a sealing ring for a chromatography column. Background Technology

[0002] Chromatography columns are essential equipment in the chromatography industry for purifying process liquids and separating desired substances from them. Currently, chromatography columns mainly consist of a column head, column barrel, and end caps. To facilitate observation of the sample purification process within the column, transparent glass column barrels are typically used. However, due to the large roundness error of ordinary glass column tubes, the column head cannot effectively seal with the column barrel. Figure 5 The diagram shows the sealing structure of a conventional chromatography column. Because the inner diameter of a conventional glass tube has a relatively large error, typically ranging from 2 to 10 mm, a sufficiently large gap (17) must be maintained between the column head pressure ring (9) and the glass column tube (7) to ensure that the column tube (7) is not damaged. Therefore, if the sealing ring (12) is too soft, it will form... Figure 6 Extrusion (18) causes the seal to fail, and if it is too hard, the sealing ring (12) and the column (7) cannot adhere to form an effective seal. Therefore, in order to ensure the seal between the column head and the glass column, the existing technology usually uses specially processed glass tubes as the column tubes of the chromatography column. At present, there are very few manufacturers in the world that can make such processed glass tubes, so the procurement cycle of such glass tubes is long and the price is expensive. Therefore, a sealing ring for the chromatography column is invented. Utility Model Content

[0003] In view of the problems existing in the sealing ring of the above and / or a certain existing chromatography column, this utility model is proposed.

[0004] Therefore, the purpose of this invention is to provide a sealing ring for a chromatography column that can solve the aforementioned existing problems.

[0005] To solve the above-mentioned technical problems, according to one aspect of the present invention, the present invention provides the following technical solution:

[0006] A sealing ring for a chromatography column includes a first handle seat, a central rod, a screw, a second handle seat, an upper flange, a column head, a column cylinder, a lower end cap, a column head pressure ring, a distributor, a support sealing ring, a sealing ring, a column head pressure ring flange, a bevel, a distributor flange, and a lip.

[0007] The column head extends into the column cylinder through the upper flange. A screw is connected to the top of the column head, and a first handle seat is provided on the top of the screw. A central rod that can move up and down is provided at the center of the screw. A distributor is fixedly connected to the bottom of the screw. The column head pressure ring passes through the screw and is sleeved on the outside of the distributor. The lower end of the column head pressure ring is provided with a column head pressure ring flange. A support sealing ring is installed at the lower end of the column head pressure ring flange. The bottom surface of the support sealing ring is provided with a bevel and a lip. The edge of the distributor is provided with a distributor flange. A sealing ring is installed in the space between the distributor flange, the bevel, and the lip.

[0008] In a preferred embodiment of the sealing ring for a chromatography column according to this utility model, the supporting sealing ring is made of an elastic material, the sealing ring is made of an elastic material, and the hardness of the sealing ring is lower than that of the supporting sealing ring.

[0009] In a preferred embodiment of the sealing ring for a chromatography column according to the present invention, the bottom end of the lip wraps around the sealing ring and is in close contact with the column cylinder.

[0010] As a preferred embodiment of the sealing ring for the chromatography column described in this utility model, the second handle seat is threadedly connected to the screw and rotatably connected to the upper flange.

[0011] As a preferred embodiment of the sealing ring for the chromatography column described in this utility model, the lower part of the column tube is equipped with a lower end cap, and the column tube and the lower end cap are in contact.

[0012] Compared with existing technologies:

[0013] 1. Simple structure and reliable sealing.

[0014] 2. The column head is less likely to damage the glass column tube.

[0015] 3. It can reduce the procurement cost and procurement cycle of glass column tubes.

[0016] 4. The column head moves up and down smoothly and the sealing ring will not roll over. Attached Figure Description

[0017] Figure 1 This is a front view schematic diagram of the structure of this utility model;

[0018] Figure 2 This utility model Figure 1 Enlarged schematic diagram of the structure at point A in the middle;

[0019] Figure 3 This is a schematic diagram of the unsealed state of the sealing structure of this utility model;

[0020] Figure 4 This is a schematic diagram of the sealing structure of this utility model in its sealed state;

[0021] Figure 5 This is a schematic diagram of the sealing structure of a conventional chromatography column;

[0022] Figure 6 This is a schematic diagram of the sealed extrusion of a conventional chromatography column.

[0023] In the diagram: 1. First handle seat; 2. Center rod; 3. Screw; 4. Second handle seat; 5. Upper flange; 6. Column head; 7. Column cylinder; 8. Lower end cover; 9. Column head pressure ring; 10. Distributor; 11. Support sealing ring; 12. Sealing ring; 13. Column head pressure ring flange; 14. Inclined surface; 15. Distributor flange; 16. Lip; 17. Gap; 18. Extrusion. Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of this utility model clearer, the embodiments of this utility model will be described in further detail below with reference to the accompanying drawings.

[0025] This invention provides a sealing ring for a chromatography column. Please refer to [link / reference]. Figures 1-4 It includes a first handle seat 1, a center rod 2, a screw 3, a second handle seat 4, an upper flange 5, a column head 6, a column cylinder 7, a lower end cover 8, a column head pressure ring 9, a distributor 10, a support sealing ring 11, a sealing ring 12, a column head pressure ring flange 13, a bevel 14, a distributor flange 15, and a lip 16.

[0026] The column head 6 extends into the column cylinder 7 through the upper flange 5. A screw 3 is connected to the top of the column head 6. A first handle seat 1 is provided on the top of the screw 3. A central rod 2 that can move up and down is provided at the center of the screw 3. The distributor 10 is fixedly connected to the bottom of the screw 3. The column head pressure ring 9 passes through the screw 3 and is sleeved on the outside of the distributor 10. The lower end of the column head pressure ring 9 is provided with a column head pressure ring flange 13. A support sealing ring 11 is installed at the lower end of the column head pressure ring flange 13. The bottom surface of the support sealing ring 11 is provided with a bevel 14 and a lip 16. The edge of the distributor 10 is provided with a distributor flange 15. A sealing ring 12 is installed in the space between the inclined surface 14 and the lip 16. The supporting sealing ring 11 is made of an elastic material, including but not limited to rubber and quartz. The sealing ring 12 is also made of an elastic material, including but not limited to rubber and quartz. The hardness of the sealing ring 12 is lower than that of the supporting sealing ring 11. The bottom end of the lip 16 wraps around the sealing ring 12 and is in close contact with the column 7. The second handle seat 4 is threaded onto the screw 3 and rotatably connected to the upper flange 5. The lower part of the column 7 is equipped with a lower end cover 8, and the column 7 and the lower end cover 8 are in contact. The center rod 2 is connected (either rotatably or fixedly, depending on the actual situation) to the bottom of the first handle seat 1, and the bottom end of the center rod 2 is fixedly installed with a column head pressure ring 9. In addition, the screw 3 passes through the upper flange 5. Figure 3As shown, the lower surface of the column head pressure ring flange 13 is set as a first inclined surface, and the support sealing ring 11 that contacts the lower surface of the column head pressure ring flange 13 is set as a second inclined surface, so that the support sealing ring 11 can generate a pushing force to move outward when squeezed, so as to achieve the effect of tightening more and more when squeezed. Specifically, when the column head pressure ring 9 is pressed down, the sealing ring 12 expands outward along the inclined surface 14 and the distributor flange 15 under the push of the column head pressure ring flange 13 and the support sealing ring 11, forcing the sealing ring 12 to press the lip 16 to generate sufficient sealing force.

[0027] In practical use, the specific steps are as follows:

[0028] Because the supporting sealing ring 11 and the sealing ring 12 are made of elastic material, and the hardness of the sealing ring 12 is lower than that of the supporting sealing ring 11, when an ordinary glass tube is used as the column cylinder 7, its inner circle dimension error is relatively large, generally reaching 2 to 10 mm. Using the softer sealing ring 12 as the sealing element can fit well with the glass tube. The supporting sealing ring 11, made of harder rubber, is tightly attached to the upper part of the sealing ring 12, and its thinner lip 16 wraps around the sealing ring 12, together fitting tightly with the column cylinder 7. Figure 6 The gap 17 shown can provide good support for the sealing ring 12, without the worry of the sealing ring being subjected to pressure inside the column like in ordinary structures. Figure 6 The extrusion shown 18 causes the sealing ring to fail. Since the supporting sealing ring 11 provides good support for the sealing ring 12, a large gap 17 can be left between the column head pressure ring 9 and the column cylinder 7 to prevent damage to the glass column cylinder 7. During use, rotating the first handle seat 1 clockwise pushes the center rod 2 downwards, simultaneously pushing the column head pressure ring 9 and the supporting sealing ring 11 downwards, thereby reducing the space between the supporting sealing ring 11 and the distributor flange 15. Because the sealing ring has low hardness, under the action of the inclined surface 14 and the distributor flange 15, the sealing ring 12 is forced to deform outwards, pushing the lip 16 together to tightly fit against the inside of the column cylinder 7, so that the column head 6 is in a position similar to... Figure 4 The sealing state is shown. At this time, the column head 6, column cylinder 7, and end cap 8 form a sealed cavity space where the column bed is located; when the first handle seat 1 is rotated counterclockwise, the center rod 2 is pulled upward, which simultaneously pulls the column head pressure ring 9 and the support sealing ring 11 upward, thereby increasing the space between the support sealing ring 11 and the distributor flange 15. Under the action of the sealing ring 12's own pulling force, it contracts inward along the inclined surface 14 and the distributor flange 15, and the sealing ring 12 and lip 16 separate from the inner wall of the column cylinder 7. At this time, as shown... Figure 3 The column head 6 shown is in the unsealed state; when the chromatography column is in the unsealed state, the height of the column head 6 can be adjusted by rotating the second handle seat 4 through the screw 3.

[0029] Although the present invention has been described above with reference to embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the features in the embodiments disclosed in this invention can be combined with each other in any way. The lack of an exhaustive description of these combinations in this specification is merely for the sake of brevity and resource conservation. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A sealing ring for a chromatography column, characterized in that, It includes a first handle seat (1), a center rod (2), a screw (3), a second handle seat (4), an upper flange (5), a column head (6), a column cylinder (7), a lower end cover (8), a column head pressure ring (9), a distributor (10), a support sealing ring (11), a sealing ring (12), a column head pressure ring flange (13), a bevel (14), a distributor flange (15), and a lip (16); The column head (6) extends into the column cylinder (7) through the upper flange (5). A screw (3) is connected to the top of the column head (6). A first handle seat (1) is provided on the top of the screw (3). A center rod (2) that can move up and down is provided in the center of the screw (3). A distributor (10) is fixedly connected to the bottom of the screw (3). The column head pressure ring (9) passes through the screw (3) and is sleeved on the outside of the distributor (10). The lower end of the column head pressure ring (9) is provided with a column head pressure ring flange (13). A support sealing ring (11) is installed at the lower end of the column head pressure ring flange (13). The bottom surface of the support sealing ring (11) is provided with a slope (14) and a lip (16). The edge of the distributor (10) is provided with a distributor flange (15). A sealing ring (12) is installed in the space between the distributor flange (15), the slope (14) and the lip (16).

2. The sealing ring for a chromatography column according to claim 1, characterized in that, The support sealing ring (11) is made of elastic material, and the sealing ring (12) is made of elastic material. The hardness of the sealing ring (12) is lower than that of the support sealing ring (11).

3. The sealing ring for a chromatography column according to claim 1, characterized in that, The bottom end of the lip (16) is wrapped with a sealing ring (12) and is in close contact with the cylinder (7).

4. The sealing ring for a chromatography column according to claim 1, characterized in that, The second handle seat (4) is threaded onto the screw (3) and rotatably connected to the upper flange (5).

5. The sealing ring for a chromatography column according to claim 1, characterized in that, The lower part of the column (7) is equipped with a lower end cover (8), and the column (7) and the lower end cover (8) are in contact.

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