Stem cell activity dynamic monitoring device

Abstract

The utility model relates to the field of stem cell monitoring, in particular to a stem cell activity dynamic monitoring device. Comprising a base plate and a shell, the base plate can clamp a plurality of culture dishes, two lead screws are rotationally connected into the shell and are perpendicular to each other in the horizontal direction, each lead screw is connected with a square frame, a bottom block is arranged at the bottom end of the base plate, and the bottom block is in sliding contact with the intersection position of the two square frames; the ends of the two lead screws penetrate out of the shell and are fixedly connected with rotating wheels. A plurality of culture dishes can be stored for culturing the stem cells, so that any culture dish can be conveniently adjusted to an optimal detection position during detection.

Description

Technical Field

[0001] This utility model relates to the field of stem cell monitoring, and more specifically to a dynamic monitoring device for stem cell activity. Background Technology

[0002] Stem cells are a type of pluripotent cell with self-renewal capacity. Due to their powerful functions, stem cells play an important role in medical applications. To study the characteristics of stem cells, they need to be cultured. During the culture process, the quality of stem cells needs to be monitored. Currently, the equipment used for monitoring stem cells requires manual movement of the culture dish to move it to the optimal detection position. However, this method requires constant adjustment, and the force is difficult to control when moving manually, which can easily lead to deviation. It is necessary to move the dish repeatedly to adjust it to the optimal position. Therefore, this application proposes a dynamic monitoring device for stem cell activity. Utility Model Content

[0003] This invention provides a dynamic monitoring device for stem cell activity, which has the advantage of being able to store multiple culture dishes for culturing stem cells, and making it easy to adjust any one of the culture dishes to the optimal detection position during detection.

[0004] A stem cell activity dynamic monitoring device includes a chassis and a shell. The chassis can hold multiple culture dishes. Inside the shell, two lead screws are rotatably connected and are perpendicular to each other in the horizontal direction. Each lead screw is connected to a square frame. A bottom block is provided at the bottom of the chassis and slides in contact with the intersection of the two square frames. The ends of the two lead screws extend out of the shell and are fixedly connected to the ends with wheels.

[0005] The bottom block has a bottom plate at its upper end and a sliding groove at its lower end, through which the chassis slides and contacts the bottom plate.

[0006] The upper end of the chassis has multiple slots, and each slot has a groove on its side wall. A clamping block slides in contact with the groove, and a spring is fixedly connected between the clamping block and the groove.

[0007] A telescopic rod is fixedly connected to the base block, and the movable end of the telescopic rod is fixedly connected to the bottom end of the base plate.

[0008] The upper part of the outer casing is provided with a glass window; a microscope is detachably connected to the outer casing, and the microscope is located directly above the glass window. Attached Figure Description

[0009] The present invention will now be described in further detail with reference to the accompanying drawings and specific implementation methods.

[0010] Figure 1 This is a schematic diagram of the monitoring device.

[0011] Figure 2 This is a schematic diagram of the lamp's structure;

[0012] Figure 3 This is a schematic diagram of the outer shell structure;

[0013] Figure 4 This is a schematic diagram of the base block structure;

[0014] Figure 5 This is a schematic diagram of the telescopic rod structure;

[0015] Figure 6 This is a schematic diagram of the chassis structure;

[0016] Figure 7 This is a schematic diagram of the box structure;

[0017] In the diagram: chassis 01; slot 02; clamping block 03; slide rail 04; base plate 05; base block 06; square frame 07; lead screw 08; rotating wheel 09; outer shell 10; revolving door 11; glass window 12; lamp 13; microscope 14; telescopic rod 15. Detailed Implementation

[0018] Reference Figures 1 to 7 The structure shown in the figure illustrates one implementation process of adjusting the position of the petri dish in this invention.

[0019] A stem cell activity dynamic monitoring device includes a base 01 and a housing 10. The base 01 can hold multiple culture dishes. Two lead screws 08 are rotatably connected inside the housing 10, and the two lead screws 08 are perpendicular to each other in the horizontal direction. Each lead screw 08 is connected to a square frame 07. A base block 06 is provided at the bottom of the base 01, and the base block 06 slides in contact with the intersection of the two square frames 07. The ends of both lead screws 08 extend out of the housing 10 and are fixedly connected to the ends with rotating wheels 09. When monitoring stem cells in the culture dishes, the device can be activated by rotating the lead screws 08. Two rotating wheels 09 rotate two lead screws 08, which in turn drive two square frames 07 to move. These square frames 07 then drive the base block 06 to move horizontally, allowing for movement to any position within the area formed by the two square frames 07. This facilitates the movement of the base 01, enabling the adjustment of the position of multiple culture dishes mounted on the base 01. It allows any one of the culture dishes to be moved to a monitoring position, ensuring that the culture dish is moved to an accurate location.

[0020] Reference Figures 1 to 7 The structure shown in the figure illustrates one aspect of the installation process in this invention that facilitates clamping.

[0021] The base block 06 has a base plate 05 on its upper end and a sliding groove 04 on its lower end. The base plate 01 slides and contacts the base plate 05 through the sliding groove 04. In order to facilitate the clamping of multiple culture dishes, the base plate 01 can be slidably removed from the base plate 05. After clamping multiple culture dishes on the base plate 01, the base plate 01 can be slid back onto the base plate 05. This makes it easy to place and clamp the culture dishes on the base plate 01 and then install the whole thing on the base plate 05.

[0022] Reference Figures 1 to 7 The structure shown in the figure illustrates one implementation process of the quick clamping method in this invention.

[0023] The upper end of the chassis 01 is provided with multiple slots 02, and each slot 02 has a groove on its side wall. A clamping block 03 slides in contact with the groove, and a spring is fixedly connected between the clamping block 03 and the groove. When the culture dish is squeezed into the slot 02 and the clamping block 03, the spring can push the clamping block 03 to clamp the culture dish in the slot 02 from the side, thereby realizing the quick clamping of the culture dish.

[0024] Reference Figures 1 to 7 The structure shown in the figure illustrates one implementation process of height adjustment in this invention.

[0025] A telescopic rod 15 is fixedly connected to the base block 06, and the movable end of the telescopic rod 15 is fixedly connected to the bottom end of the base plate 05. During the test, the base plate 05 can be raised and lowered by the telescopic rod 15, and the height of multiple culture dishes can be adjusted by the base plate 01. This allows for adjustment of the distance between the test view and the culture dishes during the test, making it easier to observe the stem cells in the culture dishes.

[0026] Reference Figures 1 to 7 The structure shown in the figure allows us to understand an easily observable implementation process of this utility model.

[0027] The outer shell 10 is provided with a glass window 12 at the upper end, which allows the culture dish inside the outer shell 10 to be directly observed through the glass window 12 during use, thus facilitating the observation of stem cells;

[0028] A microscope 14 is detachably connected to the outer shell 10, and the microscope 14 is located directly above the glass window 12. The user can use the microscope 14 to monitor the culture dish that has moved below the glass window 12 through the glass window 12, and monitor the status of the stem cells in the culture dish in a timely manner.

[0029] Reference Figures 1 to 7 The structure shown in the figure allows us to understand one implementation process of the supplementary light source in this utility model.

[0030] A lamp 13 is fixedly connected to the top of the inner part of the outer shell 10; during the detection process, the lamp 13 can be turned on to illuminate the culture dish, so that the stem cells in the culture dish can be illuminated in time during use, and sufficient light can be provided to observe the stem cells.

[0031] Reference Figures 1 to 7 The structure shown in the figure illustrates one implementation process of this utility model that facilitates easy handling and placement.

[0032] The outer shell 10 is hinged to a rotating door 11 at its front end. When placing or removing the culture dish, the rotating door 11 can be opened to easily remove the base plate 01 from the outer shell 10, thereby facilitating the mounting and dismounting of the culture dish on the base plate 01.

[0033] Reference Figures 1 to 7 The structure shown in the figure allows us to understand an easy-to-operate implementation process of this utility model.

[0034] Both the chassis 01 and the base plate 05 are made of hard rubber. The rubber material is lightweight and easy for users to carry or move.

[0035] Reference Figures 1 to 7 The structure shown in the figure allows us to understand one implementation process of the heat preservation in this utility model.

[0036] The outer shell 10 is made of heat-insulating material, which can improve the maintenance of the temperature inside the outer shell 10 and keep the temperature around the culture dish from changing too much, thereby improving the stability of stem cell culture.

Claims

1. A device for dynamic monitoring of stem cell activity, characterized in that: It includes a base (01) and an outer shell (10). The base (01) can hold multiple culture dishes. The outer shell (10) has two lead screws (08) rotatably connected inside, and the two lead screws (08) are perpendicular to each other in the horizontal direction. Each lead screw (08) is connected to a square frame (07). The bottom of the base (01) is provided with a bottom block (06), which slides in contact with the intersection of the two square frames (07). The ends of the two lead screws (08) both protrude out of the outer shell (10) and are fixedly connected to a rotating wheel (09).

2. The stem cell activity dynamic monitoring device according to claim 1, characterized in that: The bottom block (06) is provided with a bottom plate (05) at its upper end, and a sliding groove (04) is provided at the lower end of the chassis (01). The chassis (01) slides and contacts the bottom plate (05) through the sliding groove (04).

3. The stem cell activity dynamic monitoring device according to claim 2, characterized in that: The chassis (01) has multiple slots (02) on its upper end. Each slot (02) has a groove on its side wall. A clamping block (03) slides in contact with the groove. A spring is fixedly connected between the clamping block (03) and the groove.

4. The stem cell activity dynamic monitoring device according to claim 3, characterized in that: A telescopic rod (15) is fixedly connected to the bottom block (06), and the movable end of the telescopic rod (15) is fixedly connected to the bottom end of the base plate (05).

5. The stem cell activity dynamic monitoring device according to claim 4, characterized in that: The outer casing (10) is provided with a glass window (12) at its upper end.

6. The stem cell activity dynamic monitoring device according to claim 5, characterized in that: A microscope (14) is detachably connected to the outer casing (10), and the microscope (14) is located directly above the glass window (12).

7. The stem cell activity dynamic monitoring device according to claim 6, characterized in that: A lamp (13) is fixedly connected to the top of the inner part of the outer shell (10).

8. The stem cell activity dynamic monitoring device according to claim 5, characterized in that: The outer shell (10) is hinged to a revolving door (11) at its front end.

9. The stem cell activity dynamic monitoring device according to claim 5, characterized in that: The chassis (01) and the base plate (05) are both made of hard rubber.

10. The stem cell activity dynamic monitoring device according to claim 5, characterized in that: The outer shell (10) is made of heat-insulating material.

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