Dyeing device

Abstract

The utility model discloses a dyeing device which comprises a dyeing machine main body (1), and the dyeing machine main body (1) is provided with an operating mechanism for moving a slide; the dyeing machine main body (1) is provided with an accommodating space (1.1) for accommodating a dyeing box (2), and the dyeing box (2) is detachably mounted in the accommodating space (1.1); the staining box (2) is provided with an upward opening (2.1), and the operating mechanism can put the slide into the staining box (2) and take the slide out of the staining box (2). According to the utility model, a peristaltic pump and a liquid guide pipe in the prior art are omitted, so that the technical problem that the peristaltic pump and the liquid guide pipe are blocked is fundamentally solved, the failure rate of the dyeing machine can be effectively reduced, and a full-automatic dyeing machine and manual dyeing can be well compatible.

Description

TECHNICAL FIELD

[0001] The utility model relates to a dyeing device belongs to medical examination equipment technical field. BACKGROUND

[0002] Dyeing is a common technology in clinical medical examination, which is divided into manual dyeing and using full-automatic dyeing machine. Manual dyeing needs to use dropper or dropper bottle, and the operation steps are complicated, time-consuming and laborious. Because the time control of each dyeing step and the personal experience of the operator are different, the quality of the dyed piece is different, which affects the detection result. Because manual dyeing has disadvantages, many enterprises have developed dyeing instruments to replace manual operation. At present, the working principle and operation of most domestic dyeing instruments are similar to the high-efficiency automatic dyeing instrument disclosed in the Chinese invention patent application No. CN113495028A, and the basic accessories include a plurality of dyeing bottles, each of which is equipped with a peristaltic pump. The peristaltic pump transports the dyeing liquid in the dyeing bottle to the dyeing area through the liquid guide pipe. Whether it is drop dyeing or spray dyeing, after using this automatic dyeing instrument for a period of time, the pipeline is often blocked by the dyeing liquid, the instrument cannot be normally dyed, and the clinical examination work is seriously affected.

[0003] Therefore, the existing problems in clinical actual work are: 1. Manual dyeing has personal operation difference and operation batch small disadvantages; 2. Most automatic dyeing instruments in the laboratory are prone to pipeline blockage and failure; 3. "Dye residue" problem is common in pathology department and inspection department, especially those difficult-to-dissolve natural dyes such as hematoxylin, Wright's dyeing liquid, crystal violet dyeing liquid in gram staining dyeing liquid, most dyeing liquids are prone to oxidation residue ("dye precipitation"), whether it is manual operation or automatic dyeing instrument, dye residue seriously affects the dyeing effect, which is also the main reason for the pipeline blockage of the instrument; 4. When the automatic dyeing instrument fails, manual dyeing operation must be performed. However, the operator needs to pour out the dyeing liquid in the dyeing bottle equipped with the automatic dyeing instrument when performing manual dyeing, the bottle mouth of the dyeing bottle has a unique interface specially set for the liquid guide pipe, which is difficult to control the amount and easy to cause a large amount of dyeing liquid waste. UTILITY MODEL CONTENT

[0004] In order to overcome the problems in the prior art, the utility model provides a dyeing device, which is beneficial to solve the technical problem that the existing full-automatic dyeing machine is prone to blockage, and can also better adapt to the needs of manual dyeing. The specific technical scheme is as follows.

[0005] A dyeing device comprises a dyeing machine body having an operating mechanism for moving slides; the dyeing machine body has a containing space containing a dyeing box, which is detachably installed in the containing space; the dyeing box has an upwardly open opening, and the operating mechanism can put the slides into the dyeing box and take them out of the dyeing box.

[0006] The dyeing machine body is further provided with an ultrasonic vibration mechanism for ultrasonic vibration of dyeing liquid in the dyeing box and / or a magnetic stirring mechanism for stirring the dyeing liquid in the dyeing box.

[0007] By adopting the technical scheme, compared with the prior art, the peristaltic pump and the liquid guide pipe can be directly cancelled, thereby fundamentally solving the technical problem of blockage of the peristaltic pump and the liquid guide pipe; meanwhile, the dyeing box is detachably connected with the dyeing machine body, when one dyeing box dyes a prescribed number of slides, the whole dyeing box can be directly replaced, which is very simple and efficient, and no additional cleaning work is needed; in addition, when manual dyeing is needed, a spare dyeing box can be directly used or the dyeing box of the dyeing machine body can be taken out, and the slides to be dyed can be directly immersed in the dyeing liquid in the dyeing box. The ultrasonic vibration mechanism disperses the oxidized slag separated from the dyeing liquid, improves the solubility and saturation of the dye, and eliminates the negative influence of the dye slag on the dyeing effect. The magnetic stirrer generates vortex through the rotation of the stirring rod, realizes the overall circulation of the dyeing liquid, and prevents precipitation.

[0008] Further, the dyeing machine body has a plurality of the containing spaces. Preferably, the plurality of the containing spaces are arranged close to the side wall of the dyeing machine body. Preferably, the dyeing machine body is further provided with openable cover bodies corresponding to the containing spaces.

[0009] Further, the dyeing machine body further has slide rails, each of which is arranged corresponding to the containing space; the dyeing box comprises a dyeing box body and a sliding block, and the sliding block is arranged corresponding to the slide rail. Through cooperation of the slide rail and the sliding block, the dyeing box can be reliably detachably connected with the dyeing machine body. Preferably, the sliding block is arranged in a split type with the dyeing box body, and the dyeing box body can be insertedly connected with the sliding block. In this way, the dyeing box body is purchased as a consumable.

[0010] Further, the dyeing box has a sealing cover. When the dyeing box is installed in place in the dyeing machine body, the sealing cover can be removed, thereby ensuring that the dyeing box is upwardly open.

[0011] Compared with the prior art, the dyeing device has the following beneficial effects.

[0012] 1. The use of a detachable dyeing box replaces the peristaltic pump and liquid guide tube in the prior art, eliminating the need for cleaning operations on the peristaltic pump and liquid guide tube, and fundamentally solving the technical problem of blockage of the peristaltic pump and liquid guide tube, reducing equipment maintenance work and improving equipment utilization. The dyeing box with an upwardly open opening can be well compatible with full-automatic dyeing machines and manual dyeing, which is beneficial to reduce dyeing liquid waste and improve manual dyeing efficiency. The dyeing box of the utility model has simple structure and is convenient to replace; and the dyeing bottle equipped in the traditional full-automatic dyeing machine has a unique interface to adapt to the installation of the liquid guide tube, which is high in cost and inconvenient to replace.

[0013] 2. The use of a magnetic stirring-ultrasonic composite instrument on an automatic dyeing instrument can generate high-frequency pressure waves in the liquid through the cavitation effect of ultrasonic waves, form micro-bubbles and collapse instantaneously to release shock waves to directly destroy the agglomerated structure of dye particles, especially nano-sized insoluble residues. In addition, ultrasonic waves have sterilization and disinfection effects on the repeatedly used dyeing liquid in the dyeing box, preventing potential biological pollution problems. The magnetic stirrer realizes the overall circulation of the dyeing liquid by generating vortex through the rotation of the stirring rod, preventing sedimentation. Therefore, the magnetic stirring-ultrasonic composite instrument is an ideal solution to the clinical dyeing liquid residue: magnetic stirring→ maintaining liquid macroscopic uniformity, reducing sedimentation; ultrasonic wave→ crushing micro-agglomerates, improving dispersion stability.

[0014] Of course, an ultrasonic vibration mechanism or a magnetic stirring mechanism can also be selected according to specific clinical projects.

[0015] This design is especially suitable for pathological dyeing, immunohistochemistry, cell dyeing and other scenes with extremely high requirements for liquid uniformity, which can significantly improve the dyeing quality and reduce reagent waste. BRIEF DESCRIPTION OF DRAWINGS

[0016] Fig. 1 is a perspective view of the dyeing device of the utility model;

[0017] Fig. 2 is a perspective view of the dyeing device of the utility model after the cover body is opened;

[0018] Fig. 3 is a schematic view of the dyeing box.

[0019] In the figure: dyeing machine main body 1, containing space 1.1, side wall 1.2, cover body 1.3, sliding rail 1.4, dyeing box 2, opening 2.1, sliding block 2.2, dyeing box main body 2.3, sealing cover 2.4, ultrasonic vibration mechanism 3. DETAILED DESCRIPTION

[0020] The utility model will be further described in detail below in combination with the drawings.

[0021] Referring to Figs. 1-3A dyeing device comprises a dyeing machine body 1, the dyeing machine body 1 is provided with an operating mechanism (not shown) for moving a slide (not shown); the dyeing machine body 1 is provided with a containing space 1.1 containing a dyeing box 2, the dyeing box 2 is detachably installed in the containing space 1.1; the dyeing box 2 is provided with an upwardly open opening 2.1, and the operating mechanism can put the slide into the dyeing box 2 and take it out of the dyeing box 2.

[0022] The dyeing machine body 1 refers to the main part of the dyeing machine, mainly including the operating mechanism for moving the slide, the cleaning mechanism for cleaning the slide, the microscopic observation mechanism and the like. The operating mechanism is usually a mechanical arm or an XYZ three-axis sliding table module, and the operating mechanism, the cleaning mechanism and the microscopic observation mechanism are all conventional components of automatic dyeing instruments, which will not be described here.

[0023] Preferably, the dyeing machine body 1 is provided with a plurality of containing spaces 1.1. The plurality of containing spaces 1.1 are arranged close to the side wall 1.2 of the dyeing machine body 1. Preferably, the dyeing machine body 1 is also provided with an openable cover 1.3 corresponding to the containing space 1.1, which can be opened when the dyeing box 2 is replaced.

[0024] Preferably, the dyeing machine body 1 is also provided with a sliding rail 1.4 (also referred to as a sliding groove), and each sliding rail 1.4 is arranged corresponding to the containing space 1.1; the dyeing box 2 comprises a dyeing box body 2.3 and a sliding block 2.2, and the sliding block 2.2 is arranged corresponding to the sliding rail 1.4. Through the cooperation of the sliding rail 1.4 and the sliding block 2.2, the dyeing box 2 can be reliably detachably connected with the dyeing machine body 1. Preferably, the sliding block 2.2 is arranged in a split type with the dyeing box body 2.3, and the dyeing box body 2.3 can be connected with the sliding block 2.2 in a plug-in manner. In this way, the dyeing box body 2.3 can be purchased separately as consumables. Those skilled in the art can understand that there are various conventional means for detachably installing the dyeing box 2 in the dyeing machine body 1, such as using a buckle mechanism or a clamping mechanism.

[0025] Preferably, the dyeing box 2 is provided with a sealing cover 2.4. When the dyeing box 2 is installed in place in the dyeing machine body 1, the sealing cover 2.4 can be removed, so as to ensure that the dyeing box 2 is upwardly open.

[0026] In order to improve the uniformity of the dyeing liquid, the dyeing machine body 1 is also provided with an ultrasonic vibration mechanism 3, which is located below the dyeing box 2 and is used for ultrasonic vibration of the dyeing liquid in the dyeing box 2. The ultrasonic vibration mechanism 3 can disperse the macromolecular materials formed in the dyeing liquid, prevent the sediment at the bottom of the dyeing box 2, and affect the solubility and saturation of the dyeing reagent.

[0027] In order to improve the uniformity of the dyeing solution, the dyeing machine body 1 is also provided with a magnetic stirring mechanism (not shown), which can adopt existing means, such as using a magnetic suspension stirrer (CN221310385U, CN222871960U discloses a similar magnetic suspension stirring scheme), the stirring impeller (magnetic rotor) can be placed in the dyeing box for recycling, and the magnetic suspension motor (stator) is arranged on the dyeing machine body.

[0028] The skilled person in the art can understand that: the magnetic stirring mechanism and the ultrasonic vibration mechanism 3 can be used alone, but preferably, the magnetic stirring mechanism and the ultrasonic vibration mechanism 3 can be used simultaneously or alternately. The stirring speed (RPM) and the ultrasonic power (W) / frequency (kHz) are independently adjusted by the controller to avoid mutual interference and control the ultrasonic cavitation sound at <60dB (clinical environment requirement). The timing linkage program can be set: for example, first ultrasonic crushing dregs (1-2 minutes), and then switching to magnetic stirring to maintain suspension.

[0029] The dyeing device of the utility model can directly cancel the peristaltic pump and the liquid guide pipe, thereby fundamentally solving the technical problem of blockage of the peristaltic pump and the liquid guide pipe; at the same time, the dyeing box 2 is detachably connected with the dyeing machine body 1, when one dyeing box 2 dyes a specified number of slides (such as 30 people), the whole dyeing box 2 is directly replaced, which is very simple and efficient, and no additional cleaning work is needed; in addition, when manual dyeing is needed, a spare dyeing box 2 or the dyeing box 2 of the dyeing machine body 1 can be directly used, and the slides to be dyed can be directly immersed in the dyeing solution in the dyeing box 2.

[0030] The embodiments of the utility model and the features in the embodiments can be combined with each other without conflict. The utility model is not limited to the above-mentioned specific embodiments, and the above-mentioned specific embodiments are only illustrative but not limited. The person skilled in the art can make many forms under the inspiration of the utility model without departing from the purpose and the scope of protection of the claims, and these all belong to the protection scope of the utility model.

Claims

1. A staining apparatus comprising a staining machine body (1) having an operating mechanism for moving a glass slide; characterized in that, The main body (1) of the staining machine has a receiving space (1.1) for accommodating a staining box (2), which is detachably installed in the receiving space (1.1); the staining box (2) has an upward-opening opening (2.1), and the operating mechanism is capable of placing the slide into the staining box (2) and removing it from the staining box (2); The main body (1) of the dyeing machine is also provided with an ultrasonic vibration mechanism (3) and / or a magnetic stirring mechanism. The ultrasonic vibration mechanism (3) is used to perform ultrasonic vibration on the dyeing liquid in the dyeing box (2), and the magnetic stirring mechanism is used to stir the dyeing liquid in the dyeing box (2).

2. The dyeing apparatus according to claim 1, characterized in that, The main body (1) of the dyeing machine has multiple accommodating spaces (1.1).

3. The dyeing apparatus according to claim 1, characterized in that, Multiple of the aforementioned accommodating spaces (1.1) are disposed near the side wall (1.2) of the dyeing machine body (1).

4. The staining apparatus according to claim 1, characterized in that, The dyeing machine body (1) is also provided with an openable cover (1.3) corresponding to the accommodating space (1.1).

5. A dyeing apparatus according to claim 1, characterized in that, The dyeing machine body (1) also has a slide rail (1.4), each of the slide rails (1.4) being provided in relation to the accommodating space (1.1); the dyeing box (2) includes a dyeing box body (2.3) and a slider (2.2), the slider (2.2) being provided in relation to the slide rail (1.4).

6. The staining apparatus according to claim 5, characterized in that, The slider (2.2) and the dyeing box body (2.3) are separately configured, and the dyeing box body (2.3) can be plugged into the slider (2.2).

7. The staining apparatus according to claim 1, characterized in that, The dyeing box (2) has a sealing lid (2.4).

Images