Lung cancer circulating tumor cell detection equipment

Abstract

The utility model belongs to the technical field of medical instruments, particularly relates to lung cancer circulating tumor cell detection equipment, and aims to solve the problems that an existing separation vessel is connected into a groove through a bolt, the separation vessel is easy to loosen during centrifugation, and the separation vessel falls off to cause pollution, the following scheme is provided: the lung cancer circulating tumor cell detection equipment comprises a base, a vertical rod is fixed at the top end of the base, a fine adjustment bushing is fixed on the surface of the vertical rod, a fluorescence electron microscope for detection is fixed at the side end of the fine adjustment bushing, a binocular and an angle adjustment rod are arranged on the fluorescence electron microscope, and an objective lens is arranged on the lower side of the fluorescence electron microscope; an inverted-U-shaped frame is fixed to the top end of the base, a fixed frame is rotationally arranged at the top end of the inverted-U-shaped frame, a sliding frame is arranged in the fixed frame in a sliding mode, and a separation vessel used for containing tumor cells is arranged in the sliding frame; the device improves the detection efficiency and accuracy, is simple and compact in overall structure, is easy to manufacture and maintain, and reduces the production cost and the use cost.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical equipment technical field especially, relates to a lung cancer circulating tumor cell detection equipment. BACKGROUND

[0002] Circulating tumor cell refers to the tumor cell that malignant tumor disseminates and survives in peripheral blood in the development process, is closely related to tumor metastasis and prognosis, and circulating tumor cell detection refers to the method that analyzes circulating tumor cell in peripheral blood of tumor patient.

[0003] Through the retrieval, the patent with patent publication No. CN209589847U discloses a lung cancer circulating tumor cell detection device, the petri dish is connected in the groove by bolt when using, and the petri dish is loose when centrifugation, so as to cause the petri dish to fall and cause pollution, and the petri dish needs to be rotated continuously when installing the petri dish by screwing the bolt, and the efficiency of installation and removal is low, which is inconvenient to use. UTILITY MODEL CONTENT

[0004] The utility model discloses a lung cancer circulating tumor cell detection equipment to solve the shortcoming that the petri dish is connected in the groove by bolt in prior art, and the petri dish is loose when centrifugation, so as to cause the petri dish to fall and cause pollution.

[0005] In order to realize the above-mentioned purpose, the utility model adopts the following technical scheme:

[0006] A lung cancer circulating tumor cell detection equipment, including the base, the top of base is fixed with vertical rod, the surface of vertical rod is fixed with fine adjustment bushing, the side end of fine adjustment bushing is fixed with the fluorescence electron microscope for detecting, the fluorescence electron microscope is equipped with binoculars and angle adjusting rod, the lower side of fluorescence electron microscope is equipped with objective lens;

[0007] Wherein, the top of base is fixed with inverted U frame, the top of inverted U frame rotates and has fixed frame, the fixed frame slides and has sliding frame, the sliding frame is equipped with the petri dish for containing tumor cell, the petri dish is correspondingly provided with sealing cover, a group of positioning components are equipped between fixed frame and sliding frame, and the positioning component is used for positioning sliding frame;

[0008] The extrusion clamping assembly is arranged between the sliding frame and the fixed frame and is used for quickly clamping and positioning the petri dish.

[0009] In a possible design, the bottom of the inverted U frame is fixed with a driving motor, and the driving motor is fixedly connected with the fixed frame through a shaft coupling.

[0010] In a possible design, the extrusion clamping assembly comprises two second grooves formed in the sliding frame, two limiting rods are fixed in the two second grooves, two sliding plates slide on the surfaces of the four limiting rods, two connecting rods are fixed at the ends of the two sliding plates close to each other and movably penetrate into the sliding frame, two arc-shaped clamping plates are fixed at the ends of the two connecting rods close to each other and extrude the surface of the separator, two arc-shaped extrusion plates are fixed at the ends of the two sliding plates away from each other, and two extrusion plates are fixed at the top end of the fixed frame and extrude the two arc-shaped extrusion plates respectively.

[0011] In a possible design, the extrusion clamping assembly further comprises four reset springs, the four reset springs are respectively located at the ends of the two sliding plates close to each other, the four reset springs are respectively fixed in the two limiting rods, and the four reset springs are respectively sleeved on the surfaces of the four limiting rods.

[0012] In a possible design, the arc-shaped surfaces of the two arc-shaped clamping plates are provided with anti-skid pads.

[0013] In a possible design, the positioning assembly comprises a first groove formed in the sliding frame, two sliding blocks slide in the first groove, a positioning spring is fixed between the two sliding blocks, clamping rods are fixed at the ends of the two sliding blocks away from each other, two clamping grooves are formed in the fixed frame, the two clamping rods are clamped with the two clamping grooves respectively, and the side ends of the two sliding blocks are fixed with pull tabs.

[0014] In the application, when in use, the two pull tabs are pinched to make the two clamping rods respectively leave the two clamping grooves, the sliding frame is pulled outwards to pull out the sliding frame, then the separator is placed in the sliding frame, the two pull tabs are pinched again to push the sliding frame back into the fixed frame, the two sliding blocks and the clamping rods are elastically pushed by the positioning spring to move away from each other, the two clamping rods are clamped into the two clamping grooves respectively, and the positions of the sliding frame and the fixed frame are fixed.

[0015] When the sliding frame leaves the fixed frame, the arc-shaped extrusion plates lose extrusion, the sliding plates, the arc-shaped extrusion plates, the connecting rods and the arc-shaped clamping plates are reset by the elasticity of the reset springs, the two arc-shaped clamping plates move away from each other, when the sliding frame enters the fixed frame, the extrusion plates extrude the arc-shaped extrusion plates, so that the two arc-shaped clamping plates move towards each other, and the separator is stably and quickly clamped and positioned by the two arc-shaped clamping plates.

[0016] Advantages: in the application, the lung cancer circulating tumor cell detection equipment can realize quick positioning of the sliding frame and quick clamping and positioning of the separator through cooperation of the positioning assembly and the extrusion clamping assembly, and the operation convenience and stability are improved.

[0017] The utility model discloses a kind of lung cancer circulating tumor cell detection equipment, improve detection efficiency and accuracy, overall structure is simple, compact, easy to manufacture and maintain, reduce production cost and use cost. BRIEF DESCRIPTION OF DRAWINGS

[0018] Fig. 1 A kind of lung cancer circulating tumor cell detection equipment is proposed in the utility model, as shown in the figure;

[0019] Fig. 2 A kind of lung cancer circulating tumor cell detection equipment is proposed in the utility model, as shown in the figure;

[0020] Fig. 3 A kind of lung cancer circulating tumor cell detection equipment is proposed in the utility model, as shown in the figure.

[0021] In the drawing: 1, base; 2, vertical rod; 3, fine adjustment bushing; 4, clamping groove; 5, fluorescence electron microscope; 6, inverted U frame; 7, drive motor; 8, fixed frame; 9, extrusion plate; 10, sliding frame; 11, arc clamping plate; 12, separator vessel; 121, sealing cover; 13, first groove; 14, positioning spring; 15, sliding block; 16, paddle; 17, clamping rod; 18, second groove; 19, limiting rod; 20, sliding plate; 21, return spring; 22, arc extrusion plate; 23, connecting rod. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments.

[0023] Embodiment 1: refer to Figs. 1-3 A kind of detection equipment, including base 1, the top of base 1 is fixedly connected vertical rod 2, the surface of vertical rod 2 is fixedly connected fine adjustment bushing 3, fine adjustment bushing 3 side end is fixedly connected fluorescence electron microscope 5. Fluorescence electron microscope 5 is equipped with binoculars and angle adjusting rod, the downside of fluorescence electron microscope 5 is equipped with objective lens, for observing tumor cell in separator vessel 12.

[0024] The top of base 1 is also fixedly connected inverted U frame 6, the top of inverted U frame 6 is rotatably connected fixed frame 8. The bottom of inverted U frame 6 is fixedly connected drive motor 7, drive motor 7 is fixedly connected by shaft coupling and fixed frame 8, drive motor 7 drives fixed frame 8 to rotate, to realize the multiple-angle observation to sample in separator vessel 12.

[0025] The sliding frame 10 is slidably connected in the fixed frame 8, and a separation vessel 12 for accommodating tumor cells is arranged in the sliding frame 10. A sealing cover 121 is arranged on the separation vessel 12 to ensure the sealing and safety of the sample

[0026] In order to realize the positioning of the sliding frame 10, the device is designed with a positioning assembly, which specifically includes a first groove 13 arranged in the sliding frame 10, two sliding blocks 15 slidably connected in the first groove 13, and a positioning spring 14 fixedly connected between the two sliding blocks 15. The distal ends of the two sliding blocks 15 are fixedly connected with clamping rods 17, and two clamping grooves 4 are arranged in the fixed frame 8. The two clamping rods 17 are clamped with the two clamping grooves 4, thereby realizing the positioning of the sliding frame 10. The side ends of the two sliding blocks 15 are fixedly connected with push pieces 16, which facilitates the manual operation of the sliding blocks 15 to move, thereby driving the clamping rods 17 to be separated from the clamping grooves 4 and releasing the positioning of the sliding frame 10.

[0027] In order to realize the quick clamping and positioning of the separation vessel 12, the device is designed with a squeezing and clamping assembly, which specifically includes two second grooves 18 arranged in the sliding frame 10, two limiting rods 19 fixedly connected in the two second grooves 18, and two sliding plates 20 slidably connected with the surfaces of the four limiting rods 19. The proximal ends of the two sliding plates 20 are fixedly connected with connecting rods 23, the two connecting rods 23 are movably penetrated into the sliding frame 10, the proximal ends of the two connecting rods 23 are fixedly connected with arc-shaped clamping plates 11, and the two arc-shaped clamping plates 11 are in squeezing contact with the surface of the separation vessel 12. The distal ends of the two sliding plates 20 are fixedly connected with arc-shaped squeezing plates 22, and the top end of the fixed frame 8 is fixedly connected with two squeezing plates 9. The two squeezing plates 9 are in squeezing contact with the two arc-shaped squeezing plates 22, respectively. When the sliding frame 10 moves upward to a certain position, the two squeezing plates 9 squeeze the two arc-shaped squeezing plates 22, respectively, so that the two sliding plates 20 move in the direction of approaching each other, thereby driving the two arc-shaped clamping plates 11 to move in the direction of approaching each other, and realizing the clamping and positioning of the separation vessel 12.

[0028] Embodiment 2: Reference Figs. 1-3 On the basis of Embodiment 1, an improvement is made: a lung cancer circulating tumor cell detection equipment is applied in the technical field of medical devices. In order to ensure that the arc-shaped clamping plates 11 can stably clamp the separation vessel 12, the device further provides four reset springs 21 in the squeezing and clamping assembly. The four reset springs 21 are arranged at the proximal ends of the two sliding plates 20, respectively, and are fixed in the two limiting rods 19, respectively. The four reset springs 21 are sleeved on the surfaces of the four limiting rods 19, respectively. When the two squeezing plates 9 no longer squeeze the two arc-shaped squeezing plates 22, the reset springs 21 push the sliding plates 20 to reset, thereby driving the arc-shaped clamping plates 11 to release the separation vessel 12.

[0029] In order to improve the clamping stability of the arc-shaped clamping plates 11 to the separation vessel 12, the device is further provided with anti-skid pads in the arc-shaped surfaces of the two arc-shaped clamping plates 11 to prevent the separation vessel 12 from sliding off.

[0030] However, as known by those skilled in the art, the working principle and wiring method of the driving motor 7 are common, which belong to conventional means or common general knowledge, and will not be described here again, and those skilled in the art can make any selection according to their needs or convenience.

[0031] The above is only the preferred specific implementation of the present application, but the protection scope of the present application is not limited to this, any skilled person in the art can make equivalent replacement or change according to the technical scheme and the inventive concept of the present application within the technical range disclosed by the present application, which should be covered in the protection scope of the present application.

Claims

1. A lung cancer circulating tumor cell detection apparatus, characterized by, Include: The base (1), the top end of the base (1) is fixed with vertical rod (2), the surface of vertical rod (2) is fixed with fine adjustment bushing (3), the side end of fine adjustment bushing (3) is fixed with fluorescent electron microscope (5) for detection, the fluorescent electron microscope (5) is equipped with binoculars and angle adjusting rod, the lower side of fluorescent electron microscope (5) is equipped with objective lens; Wherein, the top end of the base (1) is fixed with inverted U frame (6), the top end of inverted U frame (6) is rotated with fixed frame (8), the sliding frame (10) is slidably arranged in fixed frame (8), the separator (12) for accommodating tumor cells is arranged in sliding frame (10), the sealing cover (121) is correspondingly arranged on the separator (12), a group of positioning assemblies are arranged between the fixed frame (8) and the sliding frame (10), and the positioning assemblies are used for positioning the sliding frame (10). The extrusion clamping assembly is arranged between the sliding frame (10) and the fixed frame (8) and is used for quickly clamping and positioning the separator (12).

2. The lung cancer circulating tumor cell detection device according to claim 1, wherein, The bottom end of the inverted U frame (6) is fixed with a drive motor (7), and the drive motor (7) is fixedly connected with the fixed frame (8) through a shaft coupling.

3. The lung cancer circulating tumor cell detection device according to claim 1, wherein, The extrusion clamping assembly comprises two second grooves (18) formed in the sliding frame (10), two limiting rods (19) are fixed in the two second grooves (18), two sliding plates (20) slide on the surfaces of the four limiting rods (19), two connecting rods (23) are fixed on the end portions of the two sliding plates (20) close to each other, the two connecting rods (23) are movably penetrated into the sliding frame (10), arc-shaped clamping plates (11) are fixed on the end portions of the two connecting rods (23) close to each other, the two arc-shaped clamping plates (11) are in extrusion contact with the surface of the separator (12), arc-shaped extrusion plates (22) are fixed on the end portions of the two sliding plates (20) away from each other, and two extrusion plates (9) are fixed on the top end of the fixed frame (8).

4. The lung cancer circulating tumor cell detection device according to claim 3, wherein, The extrusion clamping assembly further comprises four reset springs (21), the four reset springs (21) are respectively arranged on the end portions of the two sliding plates (20) close to each other, the four reset springs (21) are respectively fixed in the two limiting rods (19), and the four reset springs (21) are respectively sleeved on the surfaces of the four limiting rods (19).

5. The lung cancer circulating tumor cell detection device according to claim 3, wherein, The arc-shaped surfaces of the two arc-shaped clamping plates (11) are provided with anti-skid pads.

6. The lung cancer circulating tumor cell detection device according to any one of claims 1-3, wherein, The positioning assembly comprises a first groove (13) formed in the sliding frame (10), two sliding blocks (15) slide in the first groove (13), a positioning spring (14) is fixed between the two sliding blocks (15), clamping rods (17) are fixed on the end portions of the two sliding blocks (15) away from each other, two clamping grooves (4) are formed in the fixed frame (8), the two clamping rods (17) are clamped with the two clamping grooves (4) respectively, and the side ends of the two sliding blocks (15) are fixed with push pieces (16).

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