Micro-electrode linker suitable for live animal brain

Abstract

The utility model relates to the technical field of implantable microelectrodes, in particular to a microelectrode linker suitable for the brain of a living animal, which is provided with three connector units corresponding to each electrode of a miniature three-electrode system, and each connector unit comprises an electrode connecting wire main body structure and a detachable patch cord, the detachable patch cord is respectively connected with the electrode connecting line main body structure and one electrode in the miniature three-electrode system, and the electrode connecting line main body structure comprises an electrode shielding line and a GX16 reversely-installed aviation male head connected with the electrode shielding line. A signal transmission pin on the GX16 reversely-installed aviation male connector is electrically connected with a central conductor of the electrode shielding line.

Description

TECHNICAL FIELD

[0001] The utility model belongs to implantable microelectrode technical field, concretely relates to a microelectrode linker suitable for brain of living animal. BACKGROUND

[0002] Implantable intracortical microelectrode can record the action potential of neuron fast change, can be used for living level real-time in situ dopamine detection.Three electrode system can provide a stable reference electrode, be used for providing reference potential, and allow measuring electrode potential change in electrochemical reaction, the three electrode link line on market generally is constituted by shielded wire and crocodile clip currently.Crocodile clip part and implanting microelectrode of living body are connected together, and this three electrode link line is applied to living experiment.The existing electrode link line and microelectrode implanted in living body are connected with the following problems: first, when the living body moves in experiment, the electrode link line is easy to disconnect with microelectrode and even can damage electrode;Second, the weight of electrode link line limits the action of experimental living body, and at the same time can pull electrode;Third, the signal's anti-noise interference ability is low due to poor shielding, which affects the accuracy of the test personnel to calculate the change of electrochemical substance concentration in the brain of living test animal through the current voltage of measuring loop. CONTENT OF THE UTILITY MODEL

[0003] In view of above technical problem, the utility model provides a microelectrode linker suitable for brain of living animal, the microelectrode linker includes three connector units of same structure and GX16 reverse installation aviation female head combined with each connector unit;

[0004] Each connector unit includes main body structure and detachable adapter wire, and the main body structure and one electrode in micro three electrode system are electrically connected through the detachable adapter wire, wherein:

[0005] The main body structure includes electrode shielded wire, and the center conductor of the electrode shielded wire is electrically connected with a pin for transmitting signal on the GX16 reverse installation aviation female head.

[0006] As improvement, the first, second and third pins of the GX16 reverse installation aviation female head are connected with WE, CE and RE ends of electrolytic cell respectively, and the grounding pin of the GX16 reverse installation aviation female head is welded with the shielding layer of the electrode shielded wire.

[0007] As improvement, the end of the main body structure is provided with MMCX male head, and the MMCX male head is detachably combined with the matched MMCX female head at the end of the detachable adapter wire.

[0008] As improvement, the center conductor insulating layer, shielding layer and outer protective layer are sequentially wrapped outside the center conductor of the electrode shielded wire and the detachable adapter wire.

[0009] As an improvement, the detachable adapter wire is electrically connected to a gold-plated pin at one end away from the MMCX female head.

[0010] As an improvement, the detachable adapter wire is electrically connected to a gold-plated pin at one end away from the MMCX female head.

[0011] As an improvement, the detachable adapter wire is electrically connected to a gold-plated pin at one end away from the MMCX female head.

[0012] As an improvement, the detachable adapter wire is electrically connected to a gold-plated pin at one end away from the MMCX female head.

[0013] As an improvement, the detachable adapter wire is electrically connected to a gold-plated pin at one end away from the MMCX female head.

[0014] The technical scheme of the utility model can guarantee stable and reliable connection of the electrode connecting wire and the electrode structure member placed in the brain of a living animal, and reduce the load borne by the living animal. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 : some schemes of the principle diagram of the micro electrode connector suitable for the brain of a living animal;

[0016] Figure 2 : some schemes of the structural schematic diagram of the micro electrode connector suitable for the brain of a living animal; the following is the explanation of the reference numerals in the drawing:

[0017] 1, 2, 86: gold-plated pin;

[0018] 3, 4, 85: heat shrink tube;

[0019] 5, 84, 82: tail end of the adapter wire center conductor;

[0020] 6, 83, 80: adapter wire insulating layer;

[0021] 7, 81, 79: adapter wire shielding layer;

[0022] 8, 78, 76: adapter wire outer sheath;

[0023] 9, 77, 74: adapter wire shielding layer;

[0024] 10, 75, 72: adapter wire insulating layer;

[0025] 11, 73, 71: head end of the adapter wire center conductor;

[0026] 12, 13, 70: heat shrink tube;

[0027] 14, 15, 69: MMCX female center pin;

[0028] 17, 16, 68: MMCX female housing;

[0029] 18, 19, 67: MMCX female center pin head;

[0030] 20, 21, 66: MMCX male center pin tail;

[0031] 22, 24, 65: MMCX male housing;

[0032] 23, 25, 64: MMCX male center pin head;

[0033] 26, 63, 62: heat shrink tube;

[0034] 27, 61, 60: electrode shield wire center conductor tail;

[0035] 28, 58, 59: electrode shield wire insulation layer;

[0036] 29, 56, 57: electrode shield wire shield layer;

[0037] 30, 55, 54: electrode shield wire outer sheath;

[0038] 31, 53, 52: electrode shield wire shield layer;

[0039] 32, 49, 51: electrode shield wire insulation layer;

[0040] 33, 48, 50: electrode shield wire center conductor head;

[0041] 34: heat shrink tube;

[0042] 36(4), 37(6), 38(5), 45(1), 46(2), 47(3): GX16 reverse-mounted aviation male head pin tail;

[0043] 39(1), 40(5), 41(4), 42(3), 43(6), 44(2): GX16 reverse-mounted aviation male head pin head. DETAILED DESCRIPTION

[0044] The micro electrode linker suitable for the brain of a living animal in the following embodiments is used for linking an electrophysiological device and a micro three-electrode system of the brain of a living animal. The content of the utility model is further illustrated by the following embodiments, but should not be understood as limiting the utility model. The modification or replacement of the method, steps or conditions of the utility model without departing from the spirit and essence of the utility model belongs to the scope of the utility model.

[0045] Some embodiments, having 3 connector units, each connector unit comprising an electrode connection line main structure and a detachable adapter line, the detachable adapter line being connected with the electrode connection line main structure and one electrode in the micro three-electrode system respectively, the electrode connection line main structure comprising an electrode shield line and a center conductor of the electrode shield line being electrically connected with the pin of the GX16 reverse mounted aviation female base for signal transmission.

[0046] Some embodiments based on the above embodiments, such as Figure 1 As shown, the first, second and third pins of the GX16 reverse mounted aviation female base are connected with the WE, CE and RE ends of the collection module respectively, the fourth pin of the GX16 reverse mounted aviation female base is grounded; the first, second and third pins of the GX16 reverse mounted aviation female base are connected with the WE, CE and RE ends of the electrolytic cell (electrophysiological equipment) respectively, and the fourth pin of the GX16 reverse mounted aviation female base is welded with the shielding layer of the electrode shield line.

[0047] Some embodiments based on the above embodiments, the end of the main structure is provided with an MMCX male head, and the MMCX female head matched with the end of the detachable adapter line can be detachably combined with the MMCX male head.

[0048] In the above embodiments, the inner layer to the outer layer of the electrode shield line and the detachable adapter line are in turn a center conductor, a center conductor insulating layer, a shielding layer and an outer protective layer.

[0049] Some embodiments based on the above embodiments, the center conductor of the end of the detachable adapter line away from the MMCX female head is electrically connected with a gold-plated pin.

[0050] Some embodiments based on the above embodiments, the other end of the center conductor of the electrode shield line for signal transmission is electrically connected with the center pin of the MMCX male head.

[0051] Some embodiments based on the above embodiments, the end of the shielding layer of the electrode shield line away from the GX16 reverse mounted aviation female base is welded with the shell of the MMCX male head.

[0052] Some of the above schemes, the electrode shield line is an RG174 coaxial cable, and the detachable adapter line is an RF0.81 line.

[0053] A specific embodiment, such as Figure 2 , shows the complete structure of the micro electrode linker suitable for the brain of living animals.

[0054] As Figure 2The electrode linkage line comprises a first part and a second part, the first part is a main structure of the electrode linkage line, and the second part is a detachable adapter line connected with the main structure of the electrode linkage line and the microelectrode respectively.

[0055] The embodiment uses a GX16 reverse mounting aviation male connector corresponding to the GX16 reverse mounting aviation female connector of a general electrophysiological device. The GX16 reverse mounting aviation male connector is connected with an electrode shield line. The electrode shield line uses an RG174 wire, which is a coaxial cable line. The RG174 wire has a shielding structure inside, which can effectively block external electromagnetic interference, ensuring the stability and reliability of signal transmission, so as to reduce signal loss and maintain high signal transmission efficiency. The RG174 wire has strong durability and long-term stability, is suitable for long-time and high-intensity use environment, and has a certain flexibility, which flexibly meets different device layout and connection requirements. The GX16 reverse mounting fixed aviation plug has high reliability. The plug is connected by threads, is stable and reliable in plugging, is not easy to loosen, and is suitable for long-time stable working environment. The threaded connection between the plug and the socket can effectively prevent water and dust from entering. The GX16 plug considers electrical safety and mechanical safety in design, which can effectively prevent electrical fire and short circuit problems. The plug itself is made of high-quality metal, which is solid and durable, and is suitable for harsh environment and frequent use. The other end of the electrode shield line is connected with an MMCX male connector. The MMCX plug is light in weight, small in size, has low insertion loss and reflection loss, can ensure the transmission quality of signals, and has good impedance matching performance. MMCX is a plug-in connector, which adopts a twist joint structure when connected, is tightly and stably connected, is reliable, and can maintain a good connection state in a vibrating environment. The plug-in connector is reasonably designed, is easy to connect and disconnect, has good repeated plugging performance, and is suitable for scenes requiring frequent connection and disconnection.

[0056] The detachable adapter line uses an MMCX female connector matched with the MMCX male connector. The MMCX female connector is connected with another coaxial cable line RF0.81 wire. The specific connection mode is that the center conductor of the RF0.81 wire is welded with the tail end of the center pin of the MMCX female connector, and the shielding layer of the RF0.81 wire is welded with the shell of the MMCX female connector.

[0057] The RF0.81 wire has a diameter of only 0.81 mm, is small in weight and light in size, has a copper wire shielding layer, and has an external insulation layer, which all help to protect signals from interference and provide stability and reliability in signal transmission. The other end of the RF0.81 wire is connected with a pin with a diameter of about 0.8 mm. The outer layer of the pin is gold-plated, has stable contact and strong conductivity, and can provide stable signal transmission.

[0058] Each welding in the embodiment is wrapped with heat shrink tube. The heat shrink tube has good waterproof performance, can effectively prevent water vapor, humid environment from damaging the electrical connection, can provide certain mechanical protection to prevent the wire or cable from being pulled, extruded or damaged during use or installation, and can provide good insulation performance to prevent the outer skin of the wire or cable from directly contacting the external environment or other components to avoid short circuit.

[0059] In the utility model, the pin of the GX16 reverse installation type aviation male head transmitting signal is welded to the center conductor of the electrode shield line transmitting signal, the other end of the center conductor is welded to the MMCX male head center pin, the MMCX male head is twisted with the female head, the center pins on both sides are in contact, the center pin of the MMCX female head is welded to the center conductor of the adapter wire, the pin of the GX16 reverse installation type aviation male head connected to the ground is welded to the shielding layer of the electrode shield line, the other end of the shielding layer of the electrode shield line is welded to the shell of the MMCX male head, the MMCX male head is twisted with the female head, the shells on both sides are in contact, and the shell of the MMCX female head is welded to the shielding layer of the adapter wire. In this way, the center body wire and the shielding layer of the whole electrode link wire transmitting signal form a whole respectively.

[0060] It should be noted that the electrophysiological device in the above embodiment is a general electrophysiological device for those skilled in the art.

[0061] The electrophysiological device end needs to be equipped with a GX16 reverse installation type aviation female seat, the first, second and third pins of the female seat are respectively connected to the WE, CE and RE ends of the acquisition module circuit, and the fourth pin is connected to the shielding layer and the ground of the wiring between the female seat and the acquisition module circuit. The pins of the male seat and the female seat correspond one by one.

[0062] The method for using the micro electrode linker suitable for the brain of a living animal in any one of the above embodiments comprises the following steps:

[0063] S1 connects the GX16 reverse installation type aviation male head end to the GX16 reverse installation type aviation female seat of the electrophysiological device;

[0064] S2 inserts the pin end of the detachable adapter wire away from the MMCX female head into the electrode structure;

[0065] S3 connects the main body structure and the detachable adapter wire.

[0066] Particular implementations of the subject matter have been described. Other implementations are within the scope of the following claims. For example, the acts recited in the claims can be performed in a different order and still achieve desirable results. As one example, the processes described in the figures need not be performed in the particular order shown and / or sequentially.

Claims

1. A microelectrode link suitable for use in the brain of a living animal, characterized in that, The micro-electrode linker comprises three connector units with the same structure and a GX16 reverse-mounted aviation male connector combined with each of the connector units; Each connector unit comprises a main body structure and a detachable adapter wire, and the main body structure and one electrode in the micro three-electrode system are electrically connected through the detachable adapter wire, wherein: The main body structure comprises an electrode shielding wire, and a center conductor of the electrode shielding wire is electrically connected with a pin for transmitting signals on the GX16 reverse-mounted aviation male connector.

2. The microelectrode link suitable for use in the brain of a living animal as defined in claim 1, wherein The first, second and third pins of the GX16 reverse-mounted aviation male connector are respectively connected with the WE, CE and RE ends of the electrolytic cell, and a grounding pin of the GX16 reverse-mounted aviation male connector is welded with a shielding layer of the electrode shielding wire.

3. The microelectrode link suitable for use in the brain of a living animal as defined in claim 2, wherein An end of the main body structure is provided with an MMCX male connector, and the MMCX male connector is detachably combined with a matched MMCX female connector at an end of the detachable adapter wire.

4. The microelectrode link adapted for use in the brain of a living animal according to claim 3, wherein, The electrode shielding wire and the center conductor of the detachable adapter wire are sequentially wrapped with a center conductor insulation layer, a shielding layer and an outer protective layer.

5. The microelectrode link suitable for use in the brain of a living animal as defined in claim 4, wherein An end of the detachable adapter wire away from the MMCX female connector is electrically connected with a gold-plated pin.

6. The microelectrode link adapted for use in the brain of a living animal according to claim 5, wherein, A welding point of the detachable adapter wire is wrapped with an insulation protective layer.

7. The microelectrode link suitable for use in the brain of a living animal as defined in claim 6, wherein The other end of the center conductor of the electrode shielding wire for signal transmission is electrically connected with a center pin of the MMCX male connector.

8. The microelectrode link adapted for use in the brain of a living animal according to claim 7, wherein, An end of the shielding layer of the electrode shielding wire away from the GX16 reverse-mounted aviation male connector is welded with a shell of the MMCX male connector.

9. The microelectrode link suitable for use in the brain of a living animal as defined in claim 8, wherein The electrode shielding wire is an RG174 coaxial cable, and the detachable adapter wire is an RF0.81 wire.

Images