Experimental simulation box for plateau low-temperature and low-pressure environment

By introducing equipment such as vacuum pumps and air conditioners, as well as collection mechanisms, into the experimental simulation chamber, the problem of the simple structure of existing simulation chambers has been solved. This has enabled efficient environmental simulation and separation and collection of feces and urine, improved the automation and sealing performance of the experiment, and reduced the workload of experimental personnel.

CN223600565UActive Publication Date: 2025-11-28THE 953RD ARMY HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY
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Patent Information

Application Number
CN202423305933.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-11-28
Estimated Expiration
2034-12-31

AI Technical Summary

Technical Problem

The existing experimental simulation chamber has a simple structure, which makes it difficult to meet the experimental requirements and makes it inconvenient to clean up mouse feces and urine in a timely manner, resulting in inaccurate experimental data.

Method used

A high-altitude, low-temperature, and low-pressure environment experimental simulation chamber was designed, which includes a vacuum pump, a chiller, a smoke generator, a rectangular fluorescent ultraviolet lamp, and a heating tube. Combined with a collection mechanism and a sealing mechanism, it realizes environmental simulation and the separation and collection of feces and urine. The airtightness is ensured by opening and closing the sealing door through a motor.

Benefits of technology

It achieves efficient simulation of the low temperature and low pressure environment of high altitude, improves the degree of automation of experiments, ensures sealing performance, reduces the workload of experimental personnel, provides a more comfortable living environment for mice, and reduces stress response.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The utility model discloses a plateau low-temperature low-pressure environment experiment simulation box, which belongs to the technical field of experiment devices and comprises a platform plate, a box body, a collecting mechanism, a sealing mechanism, a vacuum pump, an air conditioner, a smoke generator, a barometer, a temperature sensor, a rectangular fluorescent ultraviolet lamp and two heating pipes. The collecting mechanism comprises a collecting hopper, a plurality of supporting rods, a supporting table, a guiding pipe, a collecting net, a collecting box and a dovetail block, and a vacuum pump, an air conditioner, a smoke generator, a rectangular fluorescent ultraviolet lamp and two heating pipes are arranged on the box body, so that the environmental conditions of low temperature, low pressure, ultraviolet radiation and the like in a plateau area can be flexibly simulated; and meanwhile, by improving the mode of cleaning excrement and urine of the mouse, the time and energy of experimenters can be saved, the experimenters can concentrate on the experiment, a more comfortable and sanitary living environment is provided for the mouse, and the stress reaction of experimental animals can be reduced.
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Description

TECHNICAL FIELD

[0001] The utility model belongs to experimental device technical field, provide a kind of plateau low temperature low pressure environment experimental simulation box. BACKGROUND

[0002] By the condition of mouse urine, it can provide reference for judging the influence of plateau environment on the occurrence of Parkinson's disease and its mechanism to a certain extent. First, the influence of plateau environment on mouse urine is significant. Under the plateau hypoxic environment, the composition of mouse urine will change, such as the increase of urine lactic acid excretion, the change of urine pH value and the increase of urine protein excretion. These changes reflect the physiological adaptation and metabolic adjustment of mice in plateau environment. By observing the urine condition of mice in plateau environment, the influence of plateau environment on the occurrence of Parkinson's disease can be indirectly inferred. At present, the experimental environment of mice will preferentially select experimental simulation box.

[0003] However, the overall structure of the current experimental simulation box is too simple, and the necessary conditions of each aspect are difficult to achieve the effect of experimental requirements. At the same time, it is not convenient to clean the feces and urine of mice in time, so that the experimental data cannot achieve the expected effect. UTILITY MODEL CONTENT

[0004] Therefore, the purpose of the utility model is to provide a kind of plateau low temperature low pressure environment experimental simulation box, which aims to solve the problem that the overall structure of the current experimental simulation box is too simple, and the necessary conditions of each aspect are difficult to achieve the effect of experimental requirements. At the same time, it is not convenient to clean the feces and urine of mice in time, so that the experimental data cannot achieve the expected effect.

[0005] To achieve the above purpose, the utility model provides the following technical scheme:

[0006] The utility model provides a plateau low temperature low pressure environment experiment simulation box, including platform board, box and collection mechanism, a plurality of leakage holes have on the platform board, both ends of platform board all are provided with sliding block, both inner sides of box all have the sliding slot, the front end face of box is provided with sealing mechanism, one side of box is provided with vacuum pump, the other side of box is provided with cold air machine, the top of box is provided with smoke generator, barograph and temperature sensor, the inner top of box is provided with rectangular fluorescent ultraviolet lamp, both inner sides of box all are provided with two heating pipes, and two heating pipes are located above corresponding sliding slot respectively, platform board is connected with box through sliding block and is located in the box, and sliding block is located in the sliding slot, collection mechanism includes collection bucket, a plurality of support rods and support table, the lower portion of collection bucket is connected with guide pipe, is provided with collection net in collection bucket, support table has the placement groove, the sliding setting of collection box is arranged in the placement groove, the lower portion of support table has dovetail block, the inner bottom of box has dovetail groove, collection bucket is fixedly connected with support table through a plurality of support rods and is located above support table, and guide pipe is located directly above collection box, support table is connected with box through dovetail block and is located in the box, and collection bucket is located directly below platform board, dovetail block is located in dovetail groove.

[0007] Further, the collection mechanism further comprises two insertion rods, the dovetail groove has two insertion slots, two insertion rods are respectively connected with the support table and located on the support table, and further penetrate the support table, two insertion rods are respectively inserted into the box and located in the corresponding insertion slot.

[0008] Further, the air inlet of the vacuum pump is communicated with the box, the air outlet of the cold air machine is communicated with the box, and the smoke outlet end of the smoke generator is communicated with the box.

[0009] Further, the sealing mechanism comprises two motors and a sealing door, the output end of the motor is provided with a screw rod, the two sides of the sealing door are provided with L-shaped plates, and the end of the L-shaped plate away from the sealing door has a threaded groove, the sealing door is provided with an observation glass, the rear end face of the sealing door is provided with a rectangular sealing block, the front end face of the box has a rectangular sealing groove, the rectangular sealing groove is provided with a sealing strip, two motors are fixedly connected with the box and located on both sides of the box, and are located below the vacuum pump and the cold air machine respectively, the screw rod is threadedly connected with the L-shaped plate and located in the threaded groove, and the L-shaped plate extends to both sides of the box, the rectangular sealing block is inserted into the rectangular sealing groove and abuts against the sealing strip, and the sealing door is located on the front end face of the box.

[0010] Further, the sealing mechanism further comprises a tapered block and two electric push rods, the outer side of the tapered block is provided with a sealing layer, the sealing door is provided with a tapered through hole, the tapered block is in mutual resistance with the sealing door and located in the tapered through hole, the two electric push rods are respectively fixedly connected with the sealing door and located at the rear end surface of the sealing door, and the tapered block is further fixedly connected with the corresponding electric push rod and located at the output end of the two electric push rods.

[0011] The highland low-temperature low-pressure environment experiment simulation box has the advantages that:

[0012] 1. The highland low-temperature low-pressure environment experiment simulation box can flexibly simulate the low-temperature, low-pressure, ultraviolet radiation and other environmental conditions in the plateau area, so that the desired effect of the experiment can be achieved, and the time and energy of the experimental personnel can be saved, so that they can be more focused on the experiment itself, and a more comfortable and sanitary living environment for the mice is provided, which helps to reduce the stress reaction of the experimental animals.

[0013] 2. The highland low-temperature low-pressure environment experiment simulation box is driven to rotate by the motor, so as to drive the L-shaped plate to move, realize the opening and closing of the sealing door, improve the automation degree of the experiment, ensure the tightness of the sealing door when it is closed, and the observation glass allows the experimental personnel to observe the experimental situation in the box without opening the sealing door, the rectangular sealing block and the sealing strip ensure the air tightness of the sealing door when it is closed, prevent the entry of external air or moisture, the outer side of the tapered block is provided with a sealing layer, can be tightly matched with the tapered through hole on the sealing door, the electric push rod is responsible for pushing the tapered block to move, facilitates the taking out of the collecting box, realizes a more tight sealing effect, improves the sealing performance, and increases the flexibility and reliability of the experiment.

[0014] The other advantages, objects and features of the utility model will be described in the subsequent description to some extent, and to some extent, it will be obvious to those skilled in the art based on the study of the following text or can be taught from the practice of the utility model. The objects and other advantages of the utility model can be realized and obtained by the following description. BRIEF DESCRIPTION OF DRAWINGS

[0015] In order to make the purpose, technical scheme and advantages of the utility model more clear, the preferred detailed description of the utility model will be described below in combination with the drawings, wherein:

[0016] Figure 1 is a three-dimensional view of the first embodiment of the utility model.

[0017] Figure 2 is a front view of the first embodiment of the utility model.

[0018] Figure 3 is the second embodiment of the utility model Figure 2 A-A line section view.

[0019] Figure 4 is the second embodiment of the utility model Figure 3 B-B line section view.

[0020] Figure 5 is a side view of the second embodiment of the utility model.

[0021] Figure 6 is the second embodiment of the utility model Figure 5 C-C line section view.

[0022] Figure 7 is the second embodiment of the utility model Figure 6 Local enlarged view at D.

[0023] Figure 8 is the second embodiment of the utility model Figure 5 E-E line section view.

[0024] Figure 9 is the structure schematic diagram after the sealing door of the second embodiment of the utility model is opened.

[0025] The drawings: 1 is platform board, 2 is box, 3 is leakage hole, 4 is sliding block, 5 is sliding slot, 6 is sealing mechanism, 7 is vacuum pump, 8 is cold air machine, 9 is smoke generator, 10 is air pressure gauge, 11 is temperature sensor, 12 is rectangular fluorescent ultraviolet lamp, 13 is heating pipe, 14 is collection hopper, 15 is support rod, 16 is support table, 17 is guide pipe, 18 is collection net, 19 is placing groove, 20 is collection box, 21 is dovetail block, 22 is dovetail groove, 23 is insertion rod, 24 is insertion slot, 25 is motor, 26 is sealing door, 27 is screw rod, 28 is L-shaped plate, 29 is threaded groove, 30 is observation glass, 31 is rectangular sealing block, 32 is rectangular sealing slot, 33 is sealing strip, 34 is conical block, 35 is electric push rod, 36 is conical through hole. DETAILED DESCRIPTION

[0026] The present invention will be further described below with reference to specific embodiments. The accompanying drawings are for illustrative purposes only, representing schematic diagrams rather than actual physical objects, and should not be construed as limiting the scope of this patent. To better illustrate the embodiments of the present invention, some components in the drawings may be omitted, enlarged, or reduced, and do not represent the actual dimensions of the product. It is understandable to those skilled in the art that some well-known structures and their descriptions may be omitted in the drawings.

[0027] First embodiment, such as Figures 1 to 4 As shown, this utility model discloses a high-altitude low-temperature and low-pressure environment experimental simulation chamber, comprising a platform plate 1, a chamber body 2, and a collection mechanism. The platform plate 1 has multiple drainage holes 3, and sliders 4 are provided at both ends of the platform plate 1. The chamber body 2 has sliding grooves 5 on both inner sides. A sealing mechanism 6 is provided on the front end face of the chamber body 2. A vacuum pump 7 is provided on one side of the chamber body 2, and a cooler 8 is provided on the other side. A smoke generator 9, a pressure gauge 10, and a temperature sensor 11 are provided on the top of the chamber body 2. A rectangular fluorescent ultraviolet lamp 12 is provided on the inner top of the chamber body 2. The two sides of the chamber body 2... Two heating tubes 13 are provided on the inner side, and the two heating tubes 13 are respectively located above the corresponding slide grooves 5. The platform plate 1 is slidably connected to the box body 2 through the slider 4 and is located inside the box body 2. The slider 4 is located inside the slide groove 5. By improving the overall structure of the experimental simulation box, the vacuum pump 7, the air cooler 8, the smoke generator 9, the rectangular fluorescent ultraviolet lamp 12 and the two heating tubes 13 are set on the box body 2, which can flexibly simulate the environmental conditions such as low temperature, low pressure and ultraviolet radiation in plateau areas, thereby achieving the desired experimental effect.

[0028] The collection mechanism includes a collection hopper 14, multiple support rods 15, and a support platform 16. A guide pipe 17 connects to the lower part of the collection hopper 14. A collection net 18 is installed inside the collection hopper 14. The support platform 16 has a placement groove 19, in which a collection box 20 is slidably disposed. A dovetail block 21 is located below the support platform 16. The inner bottom of the housing 2 has a dovetail groove 22. The collection hopper 14 is fixedly connected to the support platform 16 via the multiple support rods 15 and is located above the support platform 16. Furthermore, the guide tube 17 is located directly above the collection box 20, the support platform 16 is slidably connected to the box 2 via the dovetail block 21 and is located inside the box 2, and the collection hopper 14 is located directly below the platform plate 1, and the dovetail block 21 is located inside the dovetail groove 22. By improving the way of cleaning mouse feces and urine, the time and energy of the experimenters can be saved, allowing them to focus more on the experiment itself, thereby providing a more comfortable and hygienic living environment for the mice and helping to reduce the stress response of the experimental animals.

[0029] The collecting mechanism further comprises two insertion rods 23, the dovetail groove 22 is provided with two insertion slots 24, the two insertion rods 23 are respectively connected with the support table 16 in a sliding mode and are located on the support table 16 and further penetrate the support table 16, and the two insertion rods 23 are respectively inserted into the box body 2 and are located in the corresponding insertion slots 24, when the insertion rods 23 are inserted into the insertion slots 24, they can prevent the support table 16 from moving in the horizontal direction, thereby improving the safety of the experiment.

[0030] The air inlet of the vacuum pump 7 is communicated with the box body 2, the air outlet of the cold air machine 8 is communicated with the box body 2, and the smoke outlet end of the smoke generator 9 is communicated with the box body 2.

[0031] The working / implementation / use principle of the utility model is that: the mouse is placed on the platform plate 1, the vacuum pump 7, the cold air machine 8 and the rectangular fluorescent ultraviolet lamp 12 are started, and the environment in the box body 2 is simulated into a plateau low-temperature low-pressure environment under the action of the pressure gauge and the temperature sensor 11, and the smoke generator 9 can also realize fog simulation in a plateau environment, the vacuum pump 7, the cold air machine 8, the smoke generator 9, the rectangular fluorescent ultraviolet lamp 12 and the two heating pipes 13 in the design are prior art, which will not be repeated here, the urine of the mouse enters the collecting net 18 through the leakage hole 3, then flows into the guide pipe 17 through the collecting net 18 and the collecting bucket 14, and then enters the collecting box 20 through the guide pipe 17, in this process, the platform plate 1 and the collecting net 18 can facilitate the collection of mouse feces, thereby realizing the separate collection of feces and urine, facilitating the collection of different data, if the collecting mechanism needs to be disassembled, the sealing mechanism 6 is opened, the two insertion rods 23 are removed, and the support table 16 is pulled out from the dovetail groove 22, the collecting net 18 can be directly taken out of the collecting bucket 14, and the platform plate 1 can be directly pulled out of the box body 2, in this way, the technical problems that the overall structure of the current experiment simulation box is too simple, the necessary conditions thereof are difficult to meet the experimental requirements, and the mouse feces and urine cannot be cleaned in time are solved.

[0032] The second embodiment is as follows, Figures 5 to 9As shown, based on the first embodiment, the utility model discloses a plateau low temperature low pressure environment experiment simulation box, the sealing mechanism 6 includes two motor 25 and sealing door 26, the output of motor 25 is provided with screw rod 27, the both sides of sealing door 26 are provided with L-shaped plate 28, and the end of L-shaped plate 28 away from sealing door 26 has thread groove 29, the observation glass 30 is set up on sealing door 26, the rear end surface of sealing door 26 is provided with rectangular sealing block 31, the front end surface of box 2 has rectangular sealing groove 32, the rectangular sealing groove 32 is provided with sealing strip 33, two motor 25 are fixed with box 2 respectively and are located the both sides of box 2, and still are located the below of vacuum pump 7 and cold air machine 8 respectively, screw rod 27 is connected with L-shaped plate 28 in screw thread, and is located in thread groove 29, and L-shaped plate 28 extends to the both sides of box 2, rectangular sealing block 31 is inserted in rectangular sealing groove 32, and bears sealing strip 33, sealing door 26 is located the front end surface of box 2, by starting motor 25, make motor 25 clockwise transmission screw rod 27, screw rod 27 is connected with thread groove 29 in screw thread, L-shaped plate 28 is pushed sealing door 26 under the action of thread groove 29, to make sealing door 26 move away from the front end surface of box 2, at this moment, the collection mechanism can be taken out and cleaned conveniently.

[0033] The sealing mechanism 6 further comprises a tapered block 34 and two electric push rods 35, the outer side of the tapered block 34 has a sealing layer, the sealing door 26 has a tapered through hole 36, the tapered block 34 and the sealing door 26 are in contact with each other and located in the tapered through hole 36, the two electric push rods 35 are fixedly connected with the sealing door 26 and located at the rear end surface of the sealing door 26, and the tapered block 34 is also fixedly connected with the corresponding electric push rod 35 and located at the output end of the two electric push rods 35, by starting the electric push rod 35, the electric push rod 35 pushes the tapered block 34 out of the tapered groove, at this time, the collection box 20 can be taken out directly without opening the sealing door 26, thereby collecting and cleaning the urine of the mouse.

[0034] The working / implementation / use principle of the utility model is: through the motor 25 drive the screw rod 27 rotation, thereby drive the L shape board 28 remove, realize the sealing door 26's opening and closing, thereby improved the experiment's automation degree, still ensured the sealing door 26's tightness when closing, and the observation glass 30 allows the experimental personnel to observe the experiment situation in the box 2 under not opening the sealing door 26, the rectangular sealing block 31 and the sealing strip 33 then ensured the sealing door 26's air tightness when closing, prevented the outside air or moisture's entry, the outside of the conical block 34 simultaneously has sealing layer, can with the conical through -hole 36 on the sealing door 26 tight cooperation, the electric push rod 35 then is responsible for pushing the conical block 34 and removes, facilitates the collection box 20, realizes more tight sealing effect, and then improved the sealing performance, still increased the experiment's flexibility and reliability.

[0035] Finally, it is pointed out that the above examples are only used to illustrate the technical solutions of the utility model and are not limiting. Although the utility model has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the utility model can be modified or replaced equivalently without departing from the purpose and scope of the technical solutions, which should be covered in the scope of the claims of the utility model.

Claims

1. A high-altitude low-temperature and low-pressure environment experimental simulation chamber, comprising a platform plate and a chamber body, wherein the platform plate has multiple perforations, sliders are provided at both ends of the platform plate, grooves are provided on both inner sides of the chamber body, a sealing mechanism is provided on the front end face of the chamber body, a vacuum pump is provided on one side of the chamber body, a cooler is provided on the other side of the chamber body, a smoke generator, a pressure gauge and a temperature sensor are provided on the top of the chamber body, a rectangular fluorescent ultraviolet lamp is provided on the inner top of the chamber body, two heating tubes are provided on both inner sides of the chamber body, and the two heating tubes are respectively located above the corresponding grooves, the platform plate is slidably connected to the chamber body through the sliders and is located inside the chamber body, and the sliders are located within the grooves, characterized in that... It also includes collection agencies; The collection mechanism includes a collection hopper, multiple support rods, and a support platform. A guide pipe is connected to the bottom of the collection hopper, and a collection net is installed inside the collection hopper. The support platform has a placement groove, and a collection box is slidably disposed in the placement groove. A dovetail block is located below the support platform, and a dovetail groove is located at the bottom of the box. The collection hopper is fixedly connected to the support platform via the multiple support rods and is located above the support platform. The guide pipe is located directly above the collection box. The support platform is slidably connected to the box via the dovetail block and is located inside the box. The collection hopper is located directly below the platform plate, and the dovetail block is located within the dovetail groove.

2. The high-altitude cryogenic low-pressure environment simulation chamber according to claim 1, characterized in that, The collecting mechanism also includes two insert rods, and the dovetail groove has two slots. The two insert rods are slidably connected to the support platform and are located on the support platform, and also pass through the support platform. The two insert rods are also inserted into the box body and are located in the corresponding slots.

3. The high altitude cryogenic low pressure environment simulation chamber according to claim 2, wherein, The air inlet of the vacuum pump is connected to the housing, the air outlet of the air conditioner is connected to the housing, and the smoke outlet of the smoke generator is connected to the housing.

4. The high altitude cryogenic low pressure environment simulation chamber according to claim 3, wherein, The sealing mechanism includes two motors and a sealing door. The output end of each motor is equipped with a screw. L-shaped plates are provided on both sides of the sealing door, with a threaded groove at the end of the L-shaped plate furthest from the sealing door. An observation glass is provided on the sealing door. A rectangular sealing block is provided on the rear end face of the sealing door. A rectangular sealing groove is provided on the front end face of the housing, and a sealing strip is provided within the rectangular sealing groove. The two motors are fixedly connected to the housing and located on both sides of the housing, and also below the vacuum pump and the air conditioner, respectively. The screw is threadedly connected to the L-shaped plate and located within the threaded groove, with the L-shaped plate extending to both sides of the housing. The rectangular sealing block is inserted into the rectangular sealing groove and abuts against the sealing strip. The sealing door is located on the front end face of the housing.

5. The high altitude cryogenic low pressure environment simulation chamber according to claim 4, wherein, The sealing mechanism further comprises a conical block and two electric push rods, the outer side of the conical block is provided with a sealing layer, the sealing door is provided with a conical through hole, the conical block is in mutual resistance with the sealing door and located in the conical through hole, the two electric push rods are respectively fixedly connected with the sealing door and located at the rear end surface of the sealing door, and the conical block is further fixedly connected with the corresponding electric push rod and located at the output end of the two electric push rods.