A platelet antibody detection device
By designing a purification device for platelet antibody detection, a stepwise filtration of samples is achieved through the combination of a plate and an arc groove, which solves the detection error problem caused by imperfect purification in the existing technology and ensures the accuracy of the detection results.
Patent Information
- Application Number
- CN202423109777.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-17
- Publication Date
- 2025-11-28
- Estimated Expiration
- 2034-12-17
AI Technical Summary
The purification methods used in the current platelet antibody detection technology are not perfect, resulting in a large number of impurities in the sample and large errors in the detection results.
Design a purification device for platelet antibody detection, including a collection mechanism, a liquid dispensing mechanism, and a purification mechanism. Through the cooperation of the insert plate and the arc groove, the sample is filtered stepwise to retain impurities and ensure the purification effect.
The device is designed to effectively retain impurities in the sample, ensuring the accuracy of the test results.
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Figure CN223611222U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the technical field of platelet antibody detection, specifically to a platelet antibody detection impurity removal device. BACKGROUND
[0002] Platelet antibody detection, a project of physical examination, takes platelets containing known antigens to carry out solid phase, the steps are the same as platelet antigen identification, after solid phase is completed, 25ul of serum to be detected is added in the reaction hole, and the remaining steps are the same as platelet antigen identification, platelet suspension to be detected, known platelet antibody serum, centrifuge, U-shaped 96-hole reaction plate, formalin, polysorbate 20, fetal bovine serum, rabbit anti-human IgG, IgG anti-D sensitized red blood cells, take platelets containing known antigens to carry out solid phase, the steps are the same as platelet antigen identification, after solid phase is completed, 25ul of serum to be detected is added in the reaction hole, and the remaining steps are the same as platelet antigen identification.
[0003] In the platelet antibody detection experiment, due to the imperfect purification method, there are many sample heteroantibodies, and the detection result has error. CONTENT OF THE UTILITY MODEL
[0004] The utility model aims at solving one of the technical problems existing in the prior art or related art.
[0005] Therefore, the utility model adopts the technical scheme that:
[0006] A platelet antibody detection impurity removal device, including collection mechanism, liquid outlet mechanism and impurity removal mechanism, the collection mechanism includes the pipe body, with the pipe body is connected and communicates with the liquid inlet pipe, with the pipe body inner wall clamping's partition disc, liquid outlet mechanism, the liquid outlet mechanism includes the slope surface that is established at the top of the partition disc, is located in the bottom of the slope surface and is inserted with the partition disc The plugboard is opened on the plugboard, the plugboard slides through the pipe body outer wall, the impurity removal mechanism, the impurity removal mechanism includes a plurality of slots and a plurality of arc grooves that are opened in the pipe body inner wall, a plurality of arc grooves and a plurality of slots are staggered arrangement, the arc groove both ends are communicated with the inside of two slots respectively.
[0007] By adopting the above technical scheme, when carrying out the impurity removal operation, the plugboard is pulled out, the opening on the plugboard comes to the top of the slot, then the sample flows into the slot inside close to the top end of the pipe body from the slope position, then the pipe body is placed horizontally, the sample flows into another slot along the arc groove, then the step is repeated until the sample completely flows out, in this process, every time the sample passes through a slot, the heteroantibody in the sample will be intercepted, thereby completing the purification of the sample, and ensuring the accuracy of the detection result.
[0008] In a preferred example, the partition disc can further be configured to divide the pipe body into an upper cavity and a lower cavity, and the liquid inlet pipe is in communication with the inside of the upper cavity.
[0009] The utility model discloses in a preferable example can be further configured as: the plugboard inner end and outer end are all set to T shape, the plugboard outer end is connected with arc handle.
[0010] The utility model discloses in a preferable example can be further configured as: multiple slots, multiple arc grooves are all located inside lower cavity, and both communicate with the inside of lower cavity.
[0011] The utility model discloses in a preferable example can be further configured as: the top end of the liquid inlet pipe is movably sleeved with a top cover.
[0012] The utility model discloses in a preferable example can be further configured as: the bottom end of the pipe body is movably sleeved with a bottom cover, and a plurality of grooves are formed in the outer side of the bottom cover.
[0013] By adopting the above technical scheme, the utility model has the beneficial effects that:
[0014] In the utility model, when carrying out the impurity removal operation, the plugboard is pulled out, the opening on the plugboard reaches the top of the slot, then the sample flows into the slot near the top end of the pipe body from the slope position, then the pipe body is placed horizontally, the sample flows into another slot along the arc groove, then the step is repeated until the sample completely flows out, in the process, the impurity in the sample is intercepted every time the sample passes a slot, thereby completing the purification of the sample and ensuring the accuracy of the detection result. BRIEF DESCRIPTION OF DRAWINGS
[0015] Figure 1 It is the overall structure perspective drawing of the utility model;
[0016] Figure 2 It is the pipe body internal structure schematic view of the utility model;
[0017] Figure 3 It is the collection mechanism schematic view of the utility model;
[0018] Figure 4 It is the liquid outlet mechanism schematic view of the utility model;
[0019] Figure 5 It is the impurity removal mechanism schematic view of the utility model.
[0020] Reference signs:
[0021] 100, collection mechanism;110, pipe body;120, liquid inlet pipe;130, baffle;
[0022] 200, liquid outlet mechanism;210, slope;220, plugboard;230, opening;
[0023] 300, impurity removal mechanism;310, slot;320, arc groove;
[0024] 400, top cover;
[0025] 500, bottom cover. DETAILED DESCRIPTION
[0026] In order to make the purpose, technical scheme and advantages of the utility model more clear and obvious, the utility model is further explained in detail below in combination with specific embodiments and with reference to the drawings. It should be noted that the embodiments of the utility model and the features in the embodiments can be combined with each other without conflict.
[0027] It is understood that the description is only exemplary and is not intended to limit the scope of the utility model.
[0028] Some embodiments of the utility model are described below in combination with the drawings to provide a platelet antibody detection impurity removal device.
[0029] Embodiment one:
[0030] In combination with Figures 1-5 As shown in the utility model provides a platelet antibody detection impurity removal device, including collection mechanism 100, liquid outlet mechanism 200 and impurity removal mechanism 300, the collection mechanism 100 includes pipe body 110, with the pipe body 110 is connected and communicated with the liquid inlet pipe 120, with the pipe body 110 inner wall clamping disc 130 is inserted in the liquid inlet pipe 120, the liquid outlet mechanism 200 includes the slope 210 that is opened in the top of the clamping disc 130, is inserted in the plugboard 220 that is located at the bottom of the slope 210 and is inserted with the clamping disc 130, the opening 230 that is opened in the plugboard 220, the plugboard 220 slidingly penetrates the outer wall of pipe body 110;
[0031] The liquid outlet mechanism 200 includes the slope 210 that is opened in the top of the clamping disc 130, is inserted in the plugboard 220 that is located at the bottom of the slope 210 and is inserted with the clamping disc 130, the opening 230 that is opened in the plugboard 220, the plugboard 220 slidingly penetrates the outer wall of pipe body 110;
[0032] The impurity removal mechanism 300 includes a plurality of slots 310 and a plurality of arc grooves 320 opened in the inner wall of the pipe body 110, a plurality of arc grooves 320 are staggered with a plurality of slots 310, and the two ends of the arc groove 320 are respectively communicated with the inside of two slots 310.
[0033] Further, the clamping disc 130 divides the pipe body 110 into an upper cavity and a lower cavity, the liquid inlet pipe 120 is communicated with the inside of the upper cavity, and the structure design can divide the sample storage and create conditions for purifying the sample.
[0034] Further, a plurality of slots 310 and a plurality of arc grooves 320 are located inside the lower cavity and are communicated with the inside of the lower cavity, and the layout design enables the purification operation to be carried out smoothly.
[0035] Further, the pipe body 110 bottom end movable sleeve is connected with the bottom cover 500, a plurality of grooves are formed on the outer side of the bottom cover 500, and the bottom cover 500 is arranged, so that the pipe body 110 bottom end is blocked when the device is idle.
[0036] Embodiment two:
[0037] In combination with the figures shown in Figure 1 、 2 and Figure 4 , on the basis of the first embodiment, the inner end and the outer end of the plug plate 220 are arranged as T-shaped, and the outer end of the plug plate 220 is connected with an arc-shaped handle, so that the operator can conveniently pull out the plug plate 220.
[0038] Embodiment three:
[0039] In combination with the figures shown in Figures 1-2 , in the above embodiments, the top end of the liquid inlet pipe 120 is movably sleeved with the top cover 400, and the top cover 400 is arranged to prevent dust from entering the inside of the pipe body 110 from the position of the liquid inlet pipe 120.
[0040] The working principle and use process of the utility model: when the device is put into practical use, the platelet sample is injected into the upper cavity from the liquid inlet pipe 120, then the plug plate 220 is pulled out when the impurity removal operation is carried out, so that the opening 230 on the plug plate 220 reaches the top of the slot 310, then the sample flows into the slot 310 close to the top end of the pipe body 110 from the position of the slope surface 210, then the pipe body 110 is horizontally placed, so that the sample flows into another slot 310 along the arc-shaped groove 320, then the step is repeated until the sample completely flows out, in this process, the impurity antibody in the sample is intercepted every time the sample passes through a slot 310, so that the purification of the sample is completed, and the accuracy of the detection result is ensured.
[0041] Although the embodiments of the utility model have been shown and described, those skilled in the art can understand that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and purposes of the utility model, and the scope of the utility model is defined by the claims and their equivalents.
Claims
1. A platelet antibody detection impurity removal device, characterized by, Include: Collecting mechanism (100), the collecting mechanism (100) includes pipe body (110), liquid inlet pipe (120) connected with the pipe body (110) and communication, and the partition disc (130) is clamped with the inner wall of pipe body (110); Liquid outlet mechanism (200), the liquid outlet mechanism (200) includes the slope (210) opened in the top of the partition disc (130), the plug-in plate (220) is arranged in the bottom of the slope (210) and is inserted with the partition disc (130), the opening (230) is opened in the plug-in plate (220), the plug-in plate (220) is slid through the outer wall of pipe body (110); Impurity removal mechanism (300), the impurity removal mechanism (300) includes a plurality of slots (310) and a plurality of arc grooves (320) opened in the inner wall of the pipe body (110), a plurality of arc grooves (320) are staggered with a plurality of slots (310), and the two ends of the arc groove (320) are respectively communicated with the inside of two slots (310).
2. The device for removing impurities for platelet antibody detection according to claim 1, wherein The partition disc (130) divides the pipe body (110) into upper cavity and lower cavity, and the liquid inlet pipe (120) is communicated with the inside of the upper cavity.
3. The device of claim 1, wherein the device is a platelet antibody detection device. The inner end and the outer end of the plug-in plate (220) are provided with T-shaped, and the outer end of the plug-in plate (220) is connected with the arc-shaped handle.
4. The device of claim 1, wherein the device is a platelet antibody detection device. A plurality of slots (310), a plurality of arc grooves (320) are located in the inside of the lower cavity, and the two are communicated with the inside of the lower cavity.
5. The device of claim 1, wherein the device is a platelet antibody detection device. The top end of the liquid inlet pipe (120) is movably sleeved with the top cover (400).
6. The device of claim 1, wherein the device is a platelet antibody detection device. The bottom end of the pipe body (110) is movably sleeved with the bottom cover (500), and a plurality of grooves are formed in the outer side of the bottom cover (500).