Detection device

Abstract

According to the detection device, a detection card and a detector are arranged, the detection card is provided with a sampling port and an observation area, after the sampling port is used for sampling, a sample flows to the observation area, the detection card is inserted into a detection interface of the detector and clamped through a clamping area of the detection interface, and then the observation area is located between a light source module and an acquisition module of the detector; the observation area is of a transparent structure, and under the control of the main control board of the detector, the light source module emits light to irradiate the transparent structure and can emit light through the transparent structure, so that the collection module can collect samples more clearly, and the collection mode is more convenient in collection operation and good in collection effect; collected data can be detected through the main control board and displayed on the display screen of the detector, and the collection and detection mode is easy to operate, high in measurement precision and better in visualization effect.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of marking detection, especially relates to a detection device. BACKGROUND

[0002] The detection of sperm quality has become an important means to evaluate male fertility. Traditional sperm quality detection mainly relies on manual observation and analysis under a microscope. This method not only requires highly skilled technicians, but also has a complicated operation process, and the accuracy and consistency of the results are easily affected by subjective factors.

[0003] Meanwhile, in modern medical diagnosis, ovulation detection is crucial for helping women understand their reproductive cycle, optimizing reproductive planning, and treating infertility. Traditional ovulation detection methods mainly rely on hormone detection of urine or blood samples. However, these methods require expensive laboratory equipment and professional operation, and the sample collection is cumbersome, requiring a long time to visit the hospital, which is not suitable for self-use at home. This leads to the fact that the infertile population or related hormone detection users cannot keep track of their hormone levels at any time, and the success rate of pregnancy is improved.

[0004] In subsequent development, both male sperm detection and female ovulation detection use colloidal gold method for detection, which can be measured at home, but these methods also require human judgment, and their credibility and accuracy are low, and can only be used as a reference. In order to improve the accuracy of male sperm detection and female ovulation detection, in the aspect of male sperm detection, the Chinese patent application document with publication number CN117409406A discloses a sperm recognition and dynamic tracking method for sperm motility analysis, which discloses the application algorithm of lightweight network ShuffleNetV2 in sperm detection, and the paper document (Sperm motility detection based on lightweight network and dense optical flow method_Dong Rui) also discloses the application algorithm of lightweight network ShuffleNetV2 in sperm detection, which can improve the accuracy of detection, and the microfluidic biochip sperm quality analyzer with publication number CN101726578A discloses the related circuit of the sperm quality analyzer. In the aspect of female ovulation detection, with the development of microfluidic chip technology, its application in the field of biomedicine is gradually mature, and the microfluidic chip (a microfluidic chip is a small laboratory device that can integrate sample processing and analysis into a microchip, with the advantages of simple operation, low cost, and small sample size) is applied. In the field of ovulation detection, the application of microfluidic chips can provide a faster, more convenient, and more accurate detection solution.

[0005] However, the above detection methods cannot rely on the detection card using colloidal gold method to collect the detection data, so it is necessary to provide a detection device that meets the detection data collection requirements in terms of structural design. Utility model content

[0006] The utility model discloses to overcome the application of light weight network ShuffleNetV2 in sperm detection or the application of micro -fluidic chip in ovulation detection in prior art cannot rely on the detection card of colloidal gold method to carry out the collection of its to be detected data insufficient, provide a detection device.

[0007] The utility model provides a detection device, including

[0008] Detection card, the detection card has the sampling port and the observation area, the sampling port is connected to the observation area, and the observation area is a transparent structure.

[0009] Detection instrument, the detection instrument includes display screen, first shell and the light source module, collection module and main control board of setting in the first shell, the display screen, light source module and collection module all are electrically connected the main control board, and the display screen is set up on the first shell, and the first shell is equipped with detection interface, and the detection interface has the clamping area and the collection area in, and the light source module and collection module are located the opposite side of collection area.

[0010] The detection card can be inserted into the detection interface and be clamped through the clamping area, and the collection area corresponds to the observation area, and after the detection card is inserted into the detection interface, the observation area can be located between the light source module and the collection module.

[0011] Among them, the display screen, light source module and collection module are electrically connected to the main control board, the main control board can control the light source module to emit light, the main control board can control the collection module to start collection, and the main control board can process the collected data and display on the display screen.

[0012] In the scheme, after sampling, the sample flows to the observation area, and after the detection card is inserted into the detection interface and clamped through the clamping area, the observation area is located between the light source module and the collection module, and the observation area is a transparent structure, the light source module emits light on the transparent structure, can pass through the transparent structure and light, so that the collection module can more clearly collect the sample, this collection mode, collection operation is more convenient, and the collection effect is good, and the data after collection can be detected through the main control board and displayed on the display screen, this collection and detection mode is simple in operation, high in measurement precision, and better in visual effect.

[0013] Preferably, the detection card has a second shell and a transparent plate, the transparent plate is embedded in the second shell, only one side of the transparent plate protrudes out of the second shell, the side of the transparent plate protruding out of the second shell forms the observation area, the observation area is a semicircular structure, and the arc-shaped outer side of the semicircular structure faces the sampling port.

[0014] The sampling port is arranged on the second shell, and a sampling groove is arranged at the sampling port, the sampling groove protrudes out of the outer surface of the second shell, and the sampling groove is communicated with the surface of the transparent plate through the sampling port.

[0015] By arranging the sampling groove to be communicated with the surface of the transparent plate through the sampling port and the sampling groove to protrude out of the outer surface of the second shell, the sample can still not overflow after being tilted at a certain angle after sampling; the observation area is formed on only one side of the transparent plate protruding out of the second shell, so that the sample sampled by the sampling port can only flow into the observation area; and the observation area is a semicircular structure, and the arc-shaped outer side of the semicircular structure faces the sampling port, so that the sample flowing into the observation area is in a gradual manner, which is beneficial to the collection resolution of the sample by the collection module and improves the collection effect.

[0016] Preferably, the detection interface is formed by an interface assembly, the interface assembly is sequentially provided with a containing area, the card connecting area and the collection area, the height of the containing area is adapted to the thickness of the second shell, the height of the card connecting area is adapted to the thickness of the transparent plate, and semicircular ring connecting protrusions are arranged on the upper and lower sides of the card connecting area, and the semicircular arc of the semicircular ring connecting protrusions is adapted to the semicircular arc of the observation area.

[0017] After the detection card is inserted into the detection interface, the containing area is adapted to the second shell, the card connecting area and the collection area are adapted to the observation area, and the card connecting area is formed by the semicircular ring connecting protrusions; and the semicircular arc of the semicircular ring connecting protrusions is adapted to the semicircular arc of the observation area, so that the observation area is not within the containing area, the detection card is inserted in place, and the observation area can be completely collected into the collection area.

[0018] Preferably, one end of the sampling groove connected to the sampling port is smaller than the other end of the sampling groove away from the sampling port, and the sampling groove is in a prism shape.

[0019] The one end of the sampling groove connected to the sampling port is smaller than the other end of the sampling groove away from the sampling port, so that the sample flows better to the transparent plate; and the sampling groove is in a prism shape, and the corner part of the prism shape can guide the flow, so that the sample flows better to the transparent plate.

[0020] Preferably, an anti-skid protrusion is arranged on the side of the second shell away from the observation area, so as to facilitate sampling of the detection card and insertion of the detection card into the detection interface.

[0021] Preferably, the observation area has colloidal gold particles, and the sample can be preliminarily judged by using colloidal gold technology, and the color forming process of the sample by the colloidal gold technology is beneficial to the collection of the subsequent collection module.

[0022] Preferably, the light source module comprises a light source main board and a light source emitter, the light source emitter is electrically connected to the light source main board, the light source main board is arranged between the light source main board and the main control board, the light source emitter is arranged on the side of the light source main board close to the detection interface, and the emission end of the light source emitter is arranged towards the collection area.

[0023] The collection module comprises a collection main board and a collector, the collector is electrically connected to the collection main board, the collection main board is arranged between the light source main board and the main control board, the collector is arranged on the side of the collection main board close to the detection interface, the collector is connected to the lower side of the collection main board, and the collection end of the collector and the emission end of the light source emitter are arranged opposite to the collection area.

[0024] With the above arrangement position, the collection end of the collector and the emission end of the light source emitter can be arranged opposite to the collection area, and the accuracy of collection is improved; meanwhile, the arrangement positions of the light source main board and the collection main board can reasonably utilize the space, so that the internal structure of the detector is simpler, and the size of the detector is reduced.

[0025] Preferably, the light source emitter is a laser emitter or an LED lamp, and the collector is a camera or a color spectrum sensor.

[0026] The camera can collect images, and the color spectrum sensor can collect color spectrum.

[0027] Preferably, the first shell comprises an upper shell and a bottom shell, and the upper shell and the bottom shell are detachably connected.

[0028] And / or,

[0029] The display screen is arranged on the top surface of the first shell, the display screen is arranged obliquely, and the side of the display screen close to the detection interface is lower than the side of the display screen away from the detection interface, so as to facilitate the operator to watch the display screen.

[0030] And / or,

[0031] The main control board is arranged horizontally, and the bottom of the main control board is fixed to the inner bottom of the first shell through the vertically arranged positioning columns, so that the main control board is fixed through the positioning columns, the positioning columns can be lifted, direct contact between the main control board and the first shell is avoided, and the use safety is improved.

[0032] And / or

[0033] The first housing bottom array is provided with at least four pedestals, so that the structure is more stable.

[0034] Preferably, the pedestals near one side of the detection interface are higher than the pedestals near the other side.

[0035] Or,

[0036] The pedestals near one side of the detection interface can be adjusted in height.

[0037] So that after the detection card is inserted into the detection interface, the detection card is tilted downward from the sampling port to the observation area, which is beneficial to the sample flowing into the observation area.

[0038] Compared with the prior art, the utility model has the beneficial effects of:

[0039] The utility model provides a kind of detection device, by being provided with detection card and detection instrument, detection card has sampling port and observation area, sample flows to observation area after sampling port sampling, after detection card is inserted into the detection interface of detection instrument and is clamped by the clamping area of detection interface, observation area is located between the light source module and acquisition module of detection instrument, and observation area is transparent structure, under the control of the main control board of detection instrument, light source module emits light and irradiates on transparent structure, can be illuminated by passing through transparent structure, so that acquisition module can more clearly collect sample, this kind of collection mode, collection operation is more convenient, and collection effect is good, and data after collection can be detected by main control board, and be shown on the display screen of detection instrument, this kind of collection detection mode is simple to operate, and measurement precision is high, and visual effect is better. BRIEF DESCRIPTION OF DRAWINGS

[0040] Figure 1 It is structural schematic diagram of detection device;

[0041] Figure 2 It is plane schematic view of detection device;

[0042] Figure 3 It is Figure 2 Sectional view in A-A of middle;

[0043] Figure 4 It is structural schematic diagram of detection instrument;

[0044] Figure 5 It is plane schematic view of detection instrument;

[0045] Figure 6 It is Figure 5 Sectional view in B-B of middle;

[0046] Figure 7 It is front view of detection instrument;

[0047] Figure 8It is the schematic view of the internal structure of the detection instrument;

[0048] Figure 9 It is the front view of the interface assembly;

[0049] Figure 10 It is the schematic view of the interface assembly; Figure 9 It is the sectional view at C-C;

[0050] Figure 11 It is the schematic view of the interface assembly;

[0051] Figure 12 It is the schematic view of the bottom surface of the detection instrument;

[0052] Figure 13 It is the schematic view of the left side of the detection instrument;

[0053] Figure 14 It is the schematic view of the structure of the detection card;

[0054] Figure 15 It is the schematic view of the plane of the detection card;

[0055] Figure 16 It is the sectional view at D-D; Figure 15

[0056] Markings in the figure: 1, first shell; 11, upper shell; 12, bottom shell; 121, base; 2, display screen; 3, main control board; 31, positioning column; 4, light source module; 41, light source mainboard; 42, light source emitter; 5, acquisition module; 51, acquisition mainboard; 52, collector; 6, detection interface; 601, interface assembly; 61, containing area; 62, card connecting area; 621, semicircular ring card connecting protrusion; 63, acquisition area; 7, detection card; 701, second shell; 702, transparent plate; 703, sampling groove; 71, sampling port; 72, observation area; 73, anti-skid protrusion. DETAILED DESCRIPTION

[0057] The utility model will be described in further detail below in combination with specific embodiments. But this should not be understood as the above-mentioned subject matter of the utility model is limited to the following examples only, and all the technologies realized based on the content of the utility model belong to the scope of the utility model.

[0058] ​In the description of the embodiments of the present application, the terms of orientation or position relationship such as "upper", "lower", "left", "right", "center", "inner", "outer" and the like are expressed based on the orientation or position relationship shown in the drawings, or the orientation or position relationship when the product / device / apparatus of the present application is usually used. These terms of orientation or position relationship are only for the convenience of describing the present application or simplifying the description of the embodiments, and for the convenience of the technicians to quickly understand the scheme, and therefore cannot be understood as indicating or implying that a specific device / component / element must have a specific orientation or be constructed and operated in a specific position relationship, and therefore cannot be understood as limiting the present application.

[0059] In addition, the terms "horizontal", "vertical", "overhanging", "parallel" and the like do not mean that the corresponding device / component / element must be absolutely horizontal or vertical or overhanging or parallel, but can be slightly inclined or have a deviation. For example, "horizontal" only means that its direction is more horizontal relative to "vertical", and does not mean that the structure must be completely horizontal, but can be slightly inclined. Alternatively, it can be simplified to understand that the corresponding device / component / element is arranged in the direction of "horizontal", "vertical", "overhanging", "parallel" and the like, and can have an error / deviation of ±10% relative to the corresponding direction, more preferably an error / deviation of ±8% or less, more preferably an error / deviation of ±6% or less, more preferably an error / deviation of ±5% or less, and more preferably an error / deviation of ±4% or less. As long as the corresponding device / component / element is within the error / deviation range, it can still achieve its role in the scheme of the present application.

[0060] In addition, the terms "first", "second", "third" and the like in the description of the present application are only used to distinguish the same or similar components, and should not be understood as emphasizing or implying the relative importance of the specific components.

[0061] In addition, in the description of the embodiments of the present application, "several", "a plurality of", "several" represent at least 2. It can be 2, 3, 4, 5, 6, 7, 8, 9, etc. in any case, and even more than 9.

[0062] In addition, in the description of the technical scheme of the present application, unless otherwise specified / limited / limited, the terms "set", "install", "connect", "connect", "set", "lay", "arrange" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected, which can be welding, riveting, bolting, screwing and other commonly used connection means in the art. The connection can be mechanical connection, electrical connection or communication connection; it can be directly connected, or indirectly connected through an intermediate medium, or the communication between two elements.

[0063] Example 1

[0064] like Figures 1-3 As shown, a detection device includes a detection card 7 and a detector. The detection card 7 is used for sampling and can be inserted into the detection interface 6 of the detector, so that the detector can collect and analyze the sample collected by the detection card 7 and display it on the display screen 2.

[0065] like Figures 14-16 As shown, the detection card 7 has a sampling port 71 and an observation area 72. The sampling port 71 is connected to the observation area 72. The sampling port 71 is used to sample the detection sample, and the sample can flow into the observation area 72 for observation and collection. The observation area 72 is a transparent structure, which can be transparent glass.

[0066] In some embodiments, such as Figures 14-16 As shown, the detection card 7 has a second outer shell 701 and a transparent plate 702. A sampling port 71 is located in the second outer shell 701, and a sampling groove 703 is provided at the sampling port 71. The sampling groove 703 communicates with the surface of the transparent plate 702 through the sampling port 71. The sampling groove 703 protrudes from the outer surface of the second outer shell 701, ensuring that the sample will not overflow even when tilted at a certain angle after sampling. The transparent plate 702 is embedded in the second outer shell 701, with only one side of the transparent plate 702 extending out of the second outer shell 701. This extended side forms the observation area 72, ensuring that the sample sampled by the sampling port 71 can only flow into the observation area 72. The observation area 72 has a semi-circular structure, with the outer arc of the semi-circular structure facing the sampling port 71, allowing the sample to flow into the observation area 72 gradually. Figure 15 As shown, the left and right sides of the observation area 72 are positioned differently in the vertical direction, with the left and right sides being higher and the middle lower. This ensures that the middle area is the first part that can be collected, which is beneficial to the sample collection resolution of the acquisition module 5 and improves the collection effect. Furthermore, compared to using a circle, its structural volume is smaller. Compared to using a triangular or other linear structure, its gradient effect is better.

[0067] Furthermore, the end of the sampling groove 703 connected to the sampling port 71 is smaller than the end of the sampling groove 703 away from the sampling port 71, forming a funnel-like structure, which allows the sampled sample to flow better towards the transparent plate 702. The sampling groove 703 adopts a depth design, which can effectively reduce the sample loss rate. The sampling groove 703 is frustum-shaped, and compared with a frustum-shaped shape, its corner parts can guide the flow, allowing the sampled sample to flow better towards the transparent plate 702.

[0068] Furthermore, such as Figures 14-16As shown, the second shell 701 is provided with anti-skid protrusions 73 away from one side of the observation area 72, facilitating the handheld detection card 7 to sample and also facilitating the handheld detection card 7 to be inserted into the detection interface 6. The anti-skid protrusions 73 are horizontal strips protruding from the shell.

[0069] As shown in the drawings, Figures 4-6 The detection instrument includes a display screen 2, a first shell 1, a light source module 4, a collection module 5 and a main control board 3 arranged in the first shell 1. The display screen 2, the light source module 4 and the collection module 5 are electrically connected to the main control board 3. The display screen 2 is arranged on the first shell 1. The first shell 1 is provided with a detection interface 6 having a card joint area 62 and a collection area 63. The light source module 4 and the collection module 5 are located on opposite sides of the collection area 63. The detection card 7 can be inserted into the detection interface 6 and clamped through the card joint area 62. The collection area 63 corresponds to the observation area 72. After the detection card 7 is inserted into the detection interface 6, the observation area 72 can be located between the light source module 4 and the collection module 5.

[0070] As shown in the drawings, Figure 4 The first shell 1 includes an upper shell 11 and a bottom shell 12. The upper shell 11 and the bottom shell 12 are detachably connected, facilitating assembly.

[0071] As shown in the drawings, Figure 4 and Figure 7 The detection interface 6 is arranged on the front side of the first shell 1.

[0072] As shown in the drawings, Figures 4-6 and Figure 13 The display screen 2 is arranged on the top surface of the first shell 1. The display screen 2 is arranged obliquely. The side of the display screen 2 close to the detection interface 6 is lower than the side of the display screen 2 away from the detection interface 6, facilitating the operator to watch the display screen 2.

[0073] As shown in the drawings, Figure 6 and Figure 8 The main control board 3 is arranged horizontally. The bottom of the main control board 3 is fixed to the inner bottom of the first shell 1 through a plurality of vertically arranged positioning columns 31. The main control board 3 is fixed through the positioning columns 31, which can be raised, thereby avoiding direct contact between the main control board 3 and the first shell 1, and improving the use safety.

[0074] As shown in the drawings, Figure 7 , Figure 12 and Figure 13As shown, the first housing 1 bottom array is provided with at least 4 bases 121, so that the structure is more stable. As a more preferred embodiment, the base 121 near one side of the detection interface 6 is higher than the base 121 on the other side; or, the base 121 near one side of the detection interface 6 can be adjusted in height. After the detection card 7 is inserted into the detection interface 6, the detection card 7 is tilted downward from the sampling port 71 to the observation area 72, so that the sample flows into the observation area 72 from the sampling port 71, and the sample is observed in the observation area 72. Figure 2 For example, the detection card 7 is inserted horizontally, so that the lower base 121 is higher than the upper base 121, and the detection card 7 will tilt inward from the lower side to the upper side, which is beneficial to the sample flowing into the observation area 72. When all the bases 121 are at the same height, the user needs to raise the two bases in front of the sampling instrument after collecting the sample, and wait for 30 to 50 minutes for the liquefaction of the sperm sample before it flows into the observation area 72 from the sampling port.

[0075] As shown in Figure 5 , Figure 6 and Figure 8 , the light source module 4 includes a light source mainboard 41 and a light source emitter 42, the light source emitter 42 is a laser emitter or an LED lamp, etc., which can be powered by a No. 5 battery or the like, to ensure that the collection module 5 has good light conditions during collection; the light source emitter 42 is electrically connected to the light source mainboard 41, the light source mainboard 41 is arranged between the light source mainboard 41 and the main control board 3, the light source emitter 42 is arranged on the side of the light source mainboard 41 close to the detection interface 6, and the emission end of the light source emitter 42 is arranged towards the collection area 63; the collection module 5 includes a collection mainboard 51 and a collector 52, the collector 52 is a camera or a color spectrum sensor, etc., which can be used for sperm detection, etc., the resolution of the camera is above 1920*1440, and the frame rate is above 30hz, such as Logitech C920 / C922 or Intel RealSense; the color spectrum sensor can be used for ovulation detection, etc. The collector 52 is electrically connected to the collection mainboard 51, the collection mainboard 51 is arranged between the light source mainboard 41 and the main control board 3, the collector 52 is arranged on the side of the collection mainboard 51 close to the detection interface 6, the collector 52 is connected to the lower side of the collection mainboard 51, and the collection end of the collector 52 and the emission end of the light source emitter 42 are arranged opposite to the collection area 63. With the above arrangement position, the collection end of the collector 52 and the emission end of the light source emitter 42 can be arranged opposite to the collection area 63, improving the accuracy of collection; at the same time, the arrangement positions of the light source mainboard 41 and the collection mainboard 51 can reasonably utilize the space, so that the internal structure of the detection instrument is simpler, and the size of the detection instrument is reduced.

[0076] As shown in Figures 6-11As shown, the detection interface 6 is formed by an interface assembly 601, which is sequentially provided with a containing area 61, the clamping area 62 and the collection area 63. The containing area 61 is highly adapted to the thickness of the second shell 701. The clamping area 62 is highly adapted to the thickness of the transparent plate 702. The clamping area 62 is provided with a semicircular clamping protrusion 621 on the upper and lower sides. The semicircular arc of the semicircular clamping protrusion 621 is adapted to the semicircular arc of the observation area 72. Figure 3 As shown, after the detection card 7 is inserted into the detection interface 6, the containing area 61 is adapted to the second shell 701. The clamping area 62 and the collection area 63 are adapted to the observation area 72. The clamping is formed by the semicircular clamping protrusion 621. The semicircular arc of the semicircular clamping protrusion 621 is adapted to the semicircular arc of the observation area 72. The observation area 72 is ensured not to be in the range of the containing area 61. The detection card 7 is ensured to be inserted into place. The observation area 72 can be completely collected into the collection area 63.

[0077] The detection device of the embodiment is provided with the detection card 7 and the detector. The detection card 7 is provided with the sampling port 71 and the observation area 72. After the sampling port 71 is sampled, the detection card 7 is inserted into the detection interface 6 of the detector and clamped by the clamping area 62 of the detection interface 6. Then, the detection card 7 is clamped by the semicircular clamping protrusion 621. The semicircular arc of the semicircular clamping protrusion 621 is adapted to the semicircular arc of the observation area 72. The observation area 72 is ensured not to be in the range of the containing area 61. The detection card 7 is ensured to be inserted into place. The observation area 72 can be completely collected into the collection area 63. Figures 1-3As shown, because the detection card 7 is tilted downward from the sampling port 71 to the observation area 72, it is beneficial for the sample to flow into the observation area 72, and the observation area 72 is located between the light source module 4 and the collection module 5 of the detector, and the observation area 72 is a transparent structure. Under the control of the main control board 3 of the detector, the light source module 4 emits light to irradiate on the transparent structure, and the light can pass through the transparent structure to make the collection module 5 more clearly collect the sample. This collection method is more convenient for collection, and the collection effect is good. The collected data can be detected by the main control board 3 and displayed on the display screen 2 of the detector. This collection and detection method is simple to operate, has high measurement accuracy, and has better visualization effect. The main control board 3 analyzes the collected data using existing technologies, such as the ShuffleNetV2 algorithm. The lightweight network ShuffleNetV2 system is a deep convolutional neural network CNN used for computer vision tasks, and is specially designed for efficient image processing and analysis on resource-constrained devices such as mobile devices and embedded systems. ShuffleNetV2 optimizes the network structure to greatly reduce the computational complexity and parameter amount of the model while ensuring high accuracy. In the sperm quality detection device, the ShuffleNetV2 system is mainly used to analyze the sperm motion images collected by the camera. Through frame analysis technology, the system can accurately evaluate the sperm motility indicators such as movement speed and trajectory, and comprehensively judge the health status of the sperm in combination with other detection parameters. Due to its lightweight and efficient characteristics, ShuffleNetV2 is very suitable for running on portable devices to provide real-time analysis results. The built-in camera in the detector, combined with the lightweight ShuffleNetV2 network system, can collect sperm images in the observation area in real time, and automatically evaluate the sperm motility through frame analysis technology. The system can accurately judge the movement state and motility indicators of the sperm to provide accurate analysis results for the health status of the sperm. The total sperm motility rate is ≥40%, the forward motility rate is ≥32%, the linear motility rate is usually ≥80%, and the normal sperm motility frequency is 2-3 Hz. If one or two of the above values are less than the normal value, it indicates that the sperm quality is abnormal, and it is recommended to go to the hospital for detection.

[0078] In some embodiments, the observation area 72 has colloidal gold particles, which can be used to preliminarily judge the sampling sample by colloidal gold technology, and the color forming process of the sample by colloidal gold technology is beneficial to the subsequent collection of the collection module 5.

[0079] In use, the sperm sample is placed in the sampling port, and the sample is liquefied and mixed with the colloidal gold-labeled specific antibodies here. Under capillary action, the sample mixture moves along the transparent plate and passes through the detection line area where the corresponding antigen is fixed in the observation area 72 in advance. If the corresponding protein exists in the sample, the detection line will show a color band, indicating a positive result; otherwise, it is negative. Among them, the number of sperm per unit volume: the normal sperm concentration is greater than or equal to 15 million per milliliter, and if it is less than this value, it shows a single line of negative, and if it is normal, it shows a double line of positive. According to the color development of the detection line, the presence and concentration level of each protein can be judged. According to the detection results of multiple proteins, the sperm health status is comprehensively evaluated, which provides a basis for subsequent diagnosis and treatment. Among them, in the sperm quality detection, in addition to evaluating the number, motility and morphology of sperm, detecting the expression level of specific proteins in sperm is of great significance for comprehensive evaluation of sperm health status. GRISP2 protein: related to sperm formation and maturation, its expression level can reflect the development status of sperm. SP10 protein: sperm acrosome protein, involved in the process of sperm and egg combination, its level affects the fertilization ability. Txndc2 and Txndc3 proteins: involved in the antioxidant process of sperm, protecting sperm from oxidative damage and maintaining normal sperm function. By detecting the expression level of the above proteins, the functional state of sperm can be more comprehensively understood, which can assist in the diagnosis of male infertility and other reproductive health problems.

[0080] And the sperm sample flows into the observation area 72, the collector 52 is a camera, the sperm movement image in the observation area 72 is obtained through the camera, the ShuffleNetV2 algorithm is adopted in the main control board 3, the sperm motility data is analyzed by using the ShuffleNetV2 algorithm, and then the expression level of the protein detected by the colloidal gold test paper is combined to form a comprehensive evaluation of the sperm health status. Based on the comprehensive detection result, the device can provide targeted dietary and lifestyle suggestions for the user, helping to improve reproductive health. The colloidal gold technology has the characteristics of rapidness, simplicity, sensitivity and low cost, and has become an important tool in the field of sperm quality detection. By detecting the expression level of specific proteins in sperm, the colloidal gold test paper can provide key information about sperm function and health status. When combined with advanced image analysis technology such as ShuffleNetV2 system, it can realize comprehensive and accurate evaluation of sperm quality, and provide strong support for the maintenance and improvement of male reproductive health, and the color development of colloidal gold can make the sperm movement image acquisition effect better.

[0081] The above only describes preferred embodiments of the present application and is not intended to limit the present application. Any modification, equivalent replacement and improvement made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A detection device, characterized in that, include The detection card (7) has a sampling port (71) and an observation area (72), the sampling port (71) is connected to the observation area (72), and the observation area (72) is a transparent structure; The detector includes a display screen (2), a first housing (1), and a light source module (4), a data acquisition module (5), and a main control board (3) disposed within the first housing (1). The display screen (2), the light source module (4), and the data acquisition module (5) are all electrically connected to the main control board (3). The display screen (2) is disposed on the first housing (1). The first housing (1) is provided with a detection interface (6). The detection interface (6) has a snap-fit ​​area (62) and a data acquisition area (63). The light source module (4) and the data acquisition module (5) are located on opposite sides of the data acquisition area (63). The detection card (7) can be inserted into the detection interface (6) and snapped into the snap-in area (62). The acquisition area (63) corresponds to the observation area (72). After the detection card (7) is inserted into the detection interface (6), the observation area (72) can be located between the light source module (4) and the acquisition module (5).

2. The detection device according to claim 1, characterized in that, The detection card (7) has a second outer shell (701) and a transparent plate (702). The transparent plate (702) is embedded in the second outer shell (701). Only one side of the transparent plate (702) protrudes from the second outer shell (701). The side of the transparent plate (702) protruding from the second outer shell (701) forms the observation area (72). The observation area (72) has a semi-circular structure. The outer arc of the semi-circular structure faces the sampling port (71). The sampling port (71) is located on the second outer shell (701), and a sampling groove (703) is provided at the sampling port (71). The sampling groove (703) protrudes from the outer surface of the second outer shell (701), and the sampling groove (703) is connected to the surface of the transparent plate (702) through the sampling port (71).

3. The detection device according to claim 2, characterized in that, The detection interface (6) is formed by an interface component (601). The interface component (601) is provided with a receiving area (61), a snap-fit ​​area (62), and a collection area (63) in sequence. The height of the receiving area (61) is adapted to the thickness of the second outer shell (701). The height of the snap-fit ​​area (62) is adapted to the thickness of the transparent plate (702). The snap-fit ​​area (62) is provided with semi-circular snap-fit ​​protrusions (621) on the upper and lower sides. The semi-circular arc shape of the semi-circular snap-fit ​​protrusions (621) is adapted to the semi-circular arc shape of the observation area (72).

4. The detection device according to claim 2, characterized in that, The sampling groove (703) is connected to the sampling port (71) at one end, which is smaller than the end of the sampling groove (703) that is far away from the sampling port (71). The sampling groove (703) is frustum-shaped.

5. The detection device according to claim 2, characterized in that, The second outer shell (701) has anti-slip protrusions (73) on the side away from the observation area (72).

6. The detection device according to claim 1, characterized in that, The observation area (72) contains colloidal gold particles.

7. The detection device according to claim 1, characterized in that, The light source module (4) includes a light source motherboard (41) and a light source emitter (42). The light source emitter (42) is electrically connected to the light source motherboard (41). The light source motherboard (41) is located between the light source motherboard (41) and the main control board (3). The light source emitter (42) is located on the side of the light source motherboard (41) near the detection interface (6). The emitting end of the light source emitter (42) is facing the acquisition area (63). The acquisition module (5) includes an acquisition motherboard (51) and an acquisition device (52). The acquisition device (52) is electrically connected to the acquisition motherboard (51). The acquisition motherboard (51) is located between the light source motherboard (41) and the main control board (3). The acquisition device (52) is located on the side of the acquisition motherboard (51) near the detection interface (6). The acquisition device (52) is connected to the lower side of the acquisition motherboard (51). The acquisition end of the acquisition device (52) and the emission end of the light source emitter (42) are positioned opposite the acquisition area (63).

8. The detection device according to claim 7, characterized in that, The light source emitter (42) is a laser emitter or an LED light; the collector (52) is a camera or a chromatographic sensor.

9. A detection device according to any one of claims 1-8, characterized in that, The first outer shell (1) includes an upper shell (11) and a bottom shell (12), which are detachably connected; And / or, The display screen (2) is disposed on the top surface of the first housing (1), the display screen (2) is tilted, and the side of the display screen (2) closer to the detection interface (6) is lower than the side of the display screen (2) farther away from the detection interface (6); And / or, The main control board (3) is horizontally arranged, and the bottom of the main control board (3) is fixed to the bottom of the inner side of the first outer shell (1) by a number of vertically arranged positioning posts (31); And / or, The bottom array of the first housing (1) is provided with at least 4 bases (121).

10. A detection device according to claim 9, characterized in that, The base (121) on the side closer to the detection interface (6) is higher than the base (121) on the other side; or, The base (121) located near the detection interface (6) is height adjustable.

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