Biochip defect detection tool

Abstract

The utility model discloses a biochip defect detection tool, which relates to the field of chip detection and comprises an electric turntable, the electric turntable is provided with a plurality of extension arms distributed at equal intervals along the circumferential track, each extension arm is provided with a channel capable of accommodating a biochip, and a guide frame is embedded in each channel. And along with the synchronous rotation of the electric turntable and the extension arm, the positions of the biochips in the guide frame can be switched until the plurality of biochips successively reach a detection station. And a positioning plate capable of moving up and down is arranged in the guide frame. According to the utility model, the detection station can rapidly and efficiently detect a plurality of biological chips, after chip detection is completed, the chips in the guide frame can be rapidly subjected to blanking and material changing operation, and in the blanking and material changing operation process, the device has the advantages of rapidness and portability in operation, the stability of the biological chips can be kept, and the efficiency of detection work is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to chip detection field, especially a biological chip defect detection frock. BACKGROUND

[0002] Biological chip defect detection is a kind of technology for detecting the defects existing in biological chip. Biological chip is a kind of high-throughput, fast and accurate molecular analysis tool, and is widely used in the research and application of genomics, proteomics, metabolomics and other fields. However, due to some technical problems or defects caused by human factors in the preparation process of biological chip, defect detection is needed to ensure its quality and reliability. The steps of biological chip defect detection include sample preparation: the biological chip sample to be detected is treated, such as extracting DNA, RNA and other molecules, and fixed on the chip;Data acquisition: using specific instruments to scan or read the biological chip, and obtaining corresponding data;Data analysis: statistical analysis and comparison of the collected data to determine whether there is a defect. Common methods include cluster analysis, principal component analysis, etc.;Result interpretation: according to the result of data analysis, the quality and reliability of biological chip are evaluated, and corresponding improvement measures are put forward.

[0003] Biological chip defect detection is of great significance to ensure the quality and reliability of biological chip. Through defect detection, potential problems can be found and solved in time, and the use efficiency and accuracy of biological chip are improved, providing reliable technical support for scientific research and clinical application.

[0004] The existing defect detection equipment applied to biological chip has the characteristics of small and thin, so as to maintain the stability of biological chip, biological chip needs to be placed on the positioning frock of detection equipment, and then the detection equipment is started to implement defect detection operation. The positioning frock can mostly carry one biological chip for detection operation at a time. If multiple biological chips need to be detected, manual feeding and discharging operations need to be carried out on the biological chips in succession during the detection process, which consumes a lot of time and affects the efficiency of detection work. UTILITY MODEL CONTENTS

[0005] In view of the above problems, the biological chip defect detection frock is provided.

[0006] To achieve the above purpose, the technical scheme provided by the present application is as follows: a biological chip defect detection frock, comprising an electric turntable, a plurality of extension arms are arranged on the electric turntable along the circumferential track equidistantly, a channel capable of accommodating biological chips is arranged on each extension arm, a guide frame is embedded in the channel, and the biological chips located in the guide frame can switch positions with the synchronous rotation of the electric turntable and the extension arm, until a plurality of biological chips successively reach the detection station.

[0007] The positioning plate is movably arranged in the guide frame, and the biochip in the guide frame can be moved above the guide frame and separated from the channel as the positioning plate rises.

[0008] Further, a follow-up sleeve is arranged at the center position of the positioning plate, a follow-up convex ring is arranged at the bottom end of the follow-up sleeve, a driving convex ring coaxially arranged with the follow-up convex ring and a driving sleeve synchronously rotatable with the driving convex ring are arranged below the follow-up convex ring, the follow-up sleeve and the driving sleeve are connected through a pressure spring, the pressure spring is arranged at the inner side of the follow-up convex ring and the driving convex ring, the convex parts of the follow-up convex ring and the driving convex ring are staggered in the natural state, when the driving sleeve and the driving convex ring rotate, the follow-up sleeve and the follow-up convex ring synchronously rise until the pressure spring is elongated.

[0009] Further, a limiting column coaxially arranged with the pressure spring is arranged at the inner side of the pressure spring, a limiting sleeve is arranged in the follow-up sleeve, the limiting sleeve is arranged at the inner side of the pressure spring and is sleeved on the limiting column, when the follow-up sleeve and the follow-up convex ring synchronously rise, the limiting sleeve moves along the distribution direction of the limiting column.

[0010] Further, a support arm parallelly arranged with the extension arm is arranged below each of the driving sleeves, the limiting column is arranged on the support arm, a driving motor for driving the driving sleeve to rotate is arranged on the support arm, and the end of the support arm away from the driving motor is arranged on the electric turntable.

[0011] Further, two guide rods symmetrically arranged are arranged at the bottom end of the guide frame, an adapter sleeve coaxially arranged with the guide rod is arranged at the bottom end of the positioning plate, when the positioning plate moves in the guide frame, the adapter sleeve slides along the surface of the guide rod.

[0012] Further, a base is arranged below the electric turntable, a plurality of support legs equally arranged are arranged on the base

[0013] In conclusion, the technical effects and advantages of the utility model are as follows:

[0014] The utility model can make the detection station detect multiple biochips quickly and efficiently, after the chip detection is completed, the chip in the guide frame can be quickly unloaded and replaced, in the process of unloading and replacing, the operation is quick and portable, the stability of the biochip can be maintained, and the efficiency of the detection work is improved. BRIEF DESCRIPTION OF DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or prior art description. Obviously, the drawings described below are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained from these drawings without creative labor.

[0016] Figure 1 It is a three-dimensional structure schematic diagram of the present application.

[0017] Figure 2 It is a second perspective structure schematic diagram of the present application.

[0018] Figure 3 It is a schematic diagram of the structure after the positioning plate rises.

[0019] Figure 4 It is a partial structure schematic diagram of the present application.

[0020] Figure 5 It is a schematic diagram of the structure after the driving sleeve and the driving convex ring are cut open.

[0021] In the figure: 1, electric rotating disc; 2, extension arm; 21, guide frame; 22, follow-up sleeve; 23, follow-up convex ring; 24, limiting sleeve; 25, guide rod; 3, positioning plate; 31, connecting sleeve; 4, driving sleeve; 5, driving convex ring; 6, pressure spring; 7, limiting column; 8, driving motor; 9, support arm; 10, base; 11, supporting leg. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only some embodiments of the present application, not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0023] Embodiment: refer to Figures 1-3The illustrated biochip defect detection tool includes an electric rotating disc 1, the electric rotating disc 1 is provided with a plurality of extension arms 2 distributed equidistantly along the circumferential track, the extension arms 2 are each provided with a channel capable of accommodating a biochip, the channel is embedded with a guide frame 21, with the synchronous rotation of the electric rotating disc 1 and the extension arms 2, the biochip located inside the guide frame 21 can switch positions until a plurality of biochips successively reach the detection station. Therefore, during the biochip defect detection operation, the detection station can quickly and efficiently detect a plurality of biochips, and after the chip detection is completed, the chips in the guide frame 21 can be quickly unloaded and replaced without affecting the subsequent biochip detection operation, thereby improving the detection efficiency.

[0024] In order to quickly unload and replace the chips in the guide frame 21, the guide frame 21 is provided with a positioning plate 3 capable of ascending and descending, with the ascent of the positioning plate 3, the biochip located in the guide frame 21 can be moved above the guide frame 21 and separated from the channel.

[0025] As shown in Figure 4 , Figure 5 The center of the positioning plate 3 is provided with a follower sleeve 22, the bottom end of the follower sleeve 22 is provided with a follower protruding ring 23, the lower side of the follower protruding ring 23 is provided with a driving protruding ring 5 coaxially distributed therewith and a driving sleeve 4 capable of rotating synchronously with the driving protruding ring 5, the follower sleeve 22 and the driving sleeve 4 are connected through a compression spring 6, the compression spring 6 is located inside the follower protruding ring 23 and the driving protruding ring 5, and in the natural state, the protruding parts of the follower protruding ring 23 and the driving protruding ring 5 are distributed staggered. After the biochip defect detection operation is completed, the driving sleeve 4 can be controlled to rotate synchronously with the driving protruding ring 5, and in the rotating process of the two, the driving protruding ring 5 touches and lifts the follower protruding ring 23, the follower sleeve 22 rises synchronously with the follower protruding ring 23, and the compression spring 6 extends and moves until the biochip is moved above the guide frame 21 by the lifted positioning plate 3 and separated from the guide frame 21 and the channel.

[0026] During the separation of the biochip from the guide frame 21 and the channel, the biochip after the detection operation can be quickly unloaded, and after being separated from the channel and the guide frame 21, the biochip has been released from the restriction and can be transferred to the next station, and in the transfer process, the surface of the biochip can be prevented from being rubbed by the guide frame 21, thereby having the advantages of quick and portable operation.

[0027] The subsequent biochips to be detected can be placed on the surface of the positioning plate 3 above the guide frame 21, and with the re-rotation of the driving sleeve 4 and the driving protruding ring 5, the protruding parts of the follower protruding ring 23 and the driving protruding ring 5 can be staggered again, and under the elastic potential of the compression spring 6, the follower sleeve 22 and the follower protruding ring 23 can be reset, and the positioning plate 3 can also be reset synchronously.

[0028] After the positioning plate 3 is reset, the biochip on the surface thereof can fall into the guide frame 21, and the biochip can be kept stable during the rotation of the extension arm 2, the arrival at the detection station and the implementation of the detection operation.

[0029] As shown in Figure 5 , the pressure spring 6 is provided with a limiting column 7 coaxially distributed therein, and the follower sleeve 22 is provided with a limiting sleeve 24, which is located in the inner side of the pressure spring 6 and is sleeved on the limiting column 7. When the follower sleeve 22 and the follower convex ring 23 ascend synchronously, the limiting sleeve 24 moves along the distribution direction of the limiting column 7. The connection between the limiting sleeve 24 and the limiting column 7 can keep the stability of the follower sleeve 22 during movement and avoid the shaking and deviation of the follower sleeve 22 and the follower convex ring 23 during movement.

[0030] As shown in Figure 4 , the lower portion of the driving sleeve 4 is provided with a support arm 9 parallel to the extension arm 2. In order to keep the stability of the limiting column 7, the limiting column 7 is arranged on the support arm 9. The support arm 9 is provided with a driving motor 8 for driving the rotation of the driving sleeve 4, and the end of the support arm 9 away from the driving motor 8 is arranged on the electric turntable 1. Therefore, when the driving motor 8 operates, the driving sleeve 4 rotates around the limiting column 7 to drive the movement of the driving convex ring 5 and the follower convex ring 23.

[0031] As shown in Figure 5 , the bottom end of the guide frame 21 is provided with two guide rods 25 symmetrically distributed, and the bottom end of the positioning plate 3 is provided with an adapter sleeve 31 coaxially distributed with the guide rod 25. When the positioning plate 3 moves in the guide frame 21, the adapter sleeve 31 slides along the surface of the guide rod 25. The combination of the adapter sleeve 31 and the guide rod 25 can effectively avoid the shaking and deviation of the positioning plate 3 carrying the biochip during the lifting and lowering movement, and further improve the stability of the positioning plate 3.

[0032] As shown in Figure 1 , Figure 2 , in order to keep the stability of the electric turntable 1 during operation, the lower portion of the electric turntable 1 is provided with a base 10, and the base 10 is provided with a plurality of support legs 11 distributed at equal intervals. The support legs 11 can be installed on the tabletop of the detection equipment to keep the stability of the entire tooling structure.

[0033] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application has been described in detail, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, the spirit and principles of the present application, the made any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.

Claims

1. A biochip defect detection tool, characterized by: The utility model relates to a kind of biological chip detection device, including motorized turntable (1), multiple extension arms (2) are equipped on the motorized turntable (1), and extension arm (2) is equipped with the passage that can hold biological chip along equidistant distribution circumferential trajectory, embedded guide frame (21) is equipped in passage, with the synchronous rotation of motorized turntable (1), extension arm (2), biological chip located in guide frame (21) inside can switch position, until multiple biological chips reach detection station in succession; Positioning plate (3) that can be raised, located in guide frame (21) inside biological chip can be moved to guide frame (21) above, and separate passage with the rising of positioning plate (3).

2. The biochip defect inspection tool according to claim 1, wherein: The center position of the positioning plate (3) is provided with a follow-up sleeve (22), the bottom end of the follow-up sleeve (22) is provided with a follow-up convex ring (23), the bottom of the follow-up convex ring (23) is provided with a driving convex ring (5) coaxially distributed with it and a driving sleeve (4) that can rotate synchronously with the driving convex ring (5), the follow-up sleeve (22) and the driving sleeve (4) are connected by a pressure spring (6), the pressure spring (6) is located inside the follow-up convex ring (23) and the driving convex ring (5), in the natural state, the protruding parts of the follow-up convex ring (23) and the driving convex ring (5) are staggered, when the driving sleeve (4) and the driving convex ring (5) rotate, the follow-up sleeve (22) and the follow-up convex ring (23) rise synchronously until the pressure spring (6) is stretched.

3. The biochip defect inspection tool according to claim 2, wherein: The inside of the pressure spring (6) is provided with a limiting column (7) coaxially distributed with it, the follow-up sleeve (22) is provided with a limiting sleeve (24) inside, the limiting sleeve (24) is located inside the pressure spring (6), and the limiting sleeve (24) is sleeved on the limiting column (7), when the follow-up sleeve (22) and the follow-up convex ring (23) rise synchronously, the limiting sleeve (24) moves along the distribution direction of the limiting column (7).

4. The biochip defect inspection tool according to claim 3, wherein: The bottom of the driving sleeve (4) is provided with a support arm (9) parallelly distributed with the extension arm (2), the limiting column (7) is provided on the support arm (9), the support arm (9) is provided with a driving motor (8) that can drive the driving sleeve (4) to rotate, and the end of the support arm (9) away from the driving motor (8) is provided on the motorized turntable (1).

5. The biochip defect inspection tool of claim 1, wherein: The bottom of the guide frame (21) is provided with two guide rods (25) symmetrically distributed, the bottom of the positioning plate (3) is provided with a link sleeve (31) coaxially distributed with the guide rod (25), when the positioning plate (3) moves in the guide frame (21), the link sleeve (31) slides along the surface of the guide rod (25).

6. The biochip defect inspection tool of claim 1, wherein: The bottom of the motorized turntable (1) is provided with a base (10), the base (10) is provided with multiple support legs (11) equidistantly distributed.

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