Separation and purification device for small molecule drug production

Abstract

The utility model belongs to the field of small molecule medicine production, and discloses a separation and purification device for small molecule medicine production, which comprises a box cover assembly for adding raw materials in a sealed manner and condensing and purifying, and a box body assembly for holding the raw materials and heating at multiple points, a stirring assembly for stirring raw materials up and down to accelerate uniform evaporation is mounted in the box body assembly, and the box cover assembly is mounted at the top end of the box body assembly; the box body assembly comprises a machine box body, a heating mechanism used for heating from the bottom, the side face and the center at the same time is arranged in the machine box body, a waste discharge pipe is arranged on one side of the bottom of the machine box body, and a waste discharge valve is installed on the waste discharge pipe. According to the separation and purification device for small molecule medicine production, raw materials are heated at multiple points from the bottom, the side face and the center at the same time, so that uniform heating is guaranteed, and the heating speed is increased; through the arrangement of stirring the raw materials up and down, uniform heating of the raw materials is accelerated, and the evaporation speed of the raw materials is increased.

Description

Technical Field

[0001] This utility model belongs to the field of small molecule drug production, and in particular relates to a separation and purification device for small molecule drug production. Background Technology

[0002] Small molecule drugs mainly refer to chemically synthesized drugs, typically organic compounds with a molecular weight of less than 1000. Their chemical properties determine their favorable drug-forming properties and pharmacokinetic properties. Small molecule drugs account for 98% of commonly used drugs. Their small molecular weight allows them to cross cell membranes and tissue walls, effectively treating diseases. Small molecule drugs are more stable, have simpler storage conditions, are easier to administer orally, and are readily absorbed. Their simple molecular structure makes chemical synthesis easier, resulting in lower manufacturing costs. They generally do not accumulate in tissues, reducing the risk of side effects. Separation and purification are crucial steps in the production of small molecule drugs.

[0003] Comparing with Chinese Patent CN216909171U, a separation and purification device for small molecule drug production is disclosed, including a base. An insulation shell is fixedly connected to the upper surface of the base. A heating element is installed at the bottom of the insulation shell. A holding container is detachably connected to the upper surface of the heating element. A top cover is detachably connected to the upper surface of the holding container. A speed reducer is installed on the upper surface of the top cover. By incorporating a water tank, a high-pressure pump, a cleaning pipe, and a spray nozzle, a cleaning system can be formed. After use, the high-pressure pump draws water from the water tank into the cleaning pipe, which is then sprayed onto the holding container by the spray nozzle for cleaning. This ensures the holding container remains clean and improves the effectiveness of the separation and purification device for small molecule drug production.

[0004] However, the aforementioned patent only heats the bottom, and the circumferential rotation and stirring not only affect the uniformity of heating but also slow down the heating speed. Therefore, a new device needs to be designed. Utility Model Content

[0005] The purpose of this invention is to provide a separation and purification device for the production of small molecule drugs, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A separation and purification apparatus for small molecule drug production includes a lid assembly for sealing the addition of raw materials and condensing for purification, and a box assembly for holding the raw materials and heating them at multiple points. The box assembly contains an agitator for accelerating uniform evaporation by tumbling the raw materials vertically. The lid assembly is mounted on top of the box assembly. The box assembly includes a housing, inside which is a heating mechanism for simultaneous heating from the bottom, sides, and center. A waste discharge pipe with a waste discharge valve is located on one side of the bottom of the housing. The agitator includes a drive roller and a support roller, symmetrically distributed vertically. A conveyor belt is installed between the drive roller and the support roller, and several agitator plates are evenly distributed on the surface of the conveyor belt. A servo motor is located in front of the drive roller.

[0008] Furthermore: the cover assembly includes a chassis cover, the chassis cover is provided with a feed pipe, a vent pipe is provided on one side of the feed pipe, and a condenser is installed on the vent pipe.

[0009] Furthermore: a sealing gasket is affixed to the bottom surface of the chassis cover, and a sealing cap is installed on the feed pipe.

[0010] Furthermore: the heating mechanism includes a bottom heating plate, a side heating plate and a center heating plate. The bottom heating plate is installed on the bottom surface of the housing, the side heating plates are installed on the two side walls of the housing, and the center heating plate is installed in the middle of the housing and passes through the ring formed by the conveyor belt.

[0011] Furthermore, there are two agitation components, symmetrically distributed within the casing, which agitate towards the center.

[0012] Furthermore: the drive roller and the support roller are respectively connected to the sealed bearing of the housing, and the servo motor is bolted to the housing.

[0013] Compared with existing technologies, the beneficial effects are:

[0014] 1. By simultaneously heating the raw materials from multiple points—the bottom, sides, and center—uniform heating is ensured, and the heating speed is accelerated.

[0015] 2. By setting up the up-and-down stirring mechanism for the raw materials, the uniform heating of the raw materials is accelerated, thus speeding up the evaporation rate of the raw materials;

[0016] 3. By setting the raw materials to be stirred relatively towards the center, the raw materials are mixed more evenly and the heating is further accelerated. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the separation and purification device for small molecule drug production according to the present invention;

[0018] Figure 2 This is an isometric sectional view of the separation and purification apparatus for small molecule drug production described in this utility model;

[0019] Figure 3 This is a front perspective view of the housing assembly of the separation and purification device for small molecule drug production described in this utility model;

[0020] Figure 4 This is a schematic diagram of the lid assembly of a separation and purification device for small molecule drug production according to the present invention;

[0021] Figure 5 This is a schematic diagram of the stirring component of the separation and purification device for small molecule drug production described in this utility model.

[0022] In the attached diagram, the following are the reference numerals: 101, chassis; 102, bottom heating plate; 103, side heating plate; 104, center heating plate; 105, waste discharge pipe; 106, waste discharge valve; 201, chassis cover; 202, feed pipe; 203, sealing cover; 204, vent pipe; 205, condenser; 206, sealing gasket; 301, support roller; 302, conveyor belt; 303, agitator plate; 304, drive roller; 305, servo motor. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figures 1-5 A separation and purification device for the production of small molecule drugs includes a lid assembly for sealing the addition of raw materials and condensing and purifying them, and a box assembly for holding the raw materials and heating them at multiple points. The box assembly is equipped with a stirring component for stirring the raw materials from top to bottom to accelerate uniform evaporation. The lid assembly is installed on the top of the box assembly.

[0025] In this embodiment: the enclosure assembly includes a chassis 101, and a heating mechanism for simultaneous heating from the bottom, sides and center is provided inside the chassis 101. A waste discharge pipe 105 is provided on one side of the bottom of the chassis 101, and a waste discharge valve 106 is installed on the waste discharge pipe 105. The heating mechanism includes a bottom heating plate 102, a side heating plate 103 and a center heating plate 104. The bottom heating plate 102 is installed on the bottom surface of the chassis 101, and the side heating plates 103 are installed on the two side walls of the chassis 101. The central heating plate 104 is installed in the middle of the casing 101 and passes through the ring formed by the conveyor belt 302. The casing 101 holds the raw materials. The bottom heating plate 102 heats the raw materials from the bottom surface of the casing 101, the side heating plates 103 heat the raw materials from the side walls of the casing 101, and the central heating plate 104 heats the raw materials from the center of the casing 101. This ensures uniform heating and speeds up the heating process. After the separation and purification are completed, the waste discharge valve 106 is opened to discharge the waste liquid from the waste discharge pipe 105.

[0026] In this embodiment: the cover assembly includes a cover 201, a sealing gasket 206 is attached to the bottom surface of the cover 201, a feed pipe 202 is provided on the cover 201, an outlet pipe 204 is provided on one side of the feed pipe 202, a condenser 205 is installed on the outlet pipe 204, and a sealing cap 203 is installed on the feed pipe 202; the sealing gasket 206 is attached to the bottom surface of the cover 201, and the sealing cap 203 is installed on the feed pipe 202; the raw material is first fed into the housing 101 through the feed pipe 202 and the cover 201, and then the sealing cap 203 is put on. The sealing gasket 206 ensures that the cover 201 and the housing 101 are in contact and sealed. After the raw material is evaporated and separated, the steam is discharged from the outlet pipe 204 and condensed and purified by the condenser 205 before flowing out;

[0027] In this embodiment: the agitation assembly includes a drive roller 304 and a support roller 301, which are symmetrically distributed vertically. A conveyor belt 302 is installed between the drive roller 304 and the support roller 301. Several agitation plates 303 are evenly distributed on the surface of the conveyor belt 302. A servo motor 305 is provided in front of the drive roller 304. There are two agitation assemblies, which are symmetrically distributed inside the housing 101 and tumble towards the center. The drive roller 304 and the support roller 301 are respectively connected to the sealed bearings of the housing 101, and the servo motor 305 is bolted to the housing 101. The two servo motors 305 drive the drive roller 304 to push the conveyor belt 302 to move under the support of the support roller 301, thereby driving the agitation plates 303 to move up and down in a circular motion, tumbling the raw materials towards the center and accelerating evaporation and separation.

[0028] Working principle: First, the raw material is fed into the machine body 101 through the feed pipe 202 and the cover 201. Then, the sealing cover 203 is closed. The bottom heating plate 102 heats the raw material from the bottom surface of the machine body 101, the side heating plates 103 heat the raw material from the two side walls of the machine body 101, and the center heating plate 104 heats the raw material from the center of the machine body 101. At the same time, two servo motors 305 drive the active roller 304 to push the conveyor belt 302 to move under the support of the support roller 301, which drives the stirring plate 303 to move up and down in a circular motion, stirring the raw material towards the center to accelerate evaporation and separation. The steam is discharged from the gas outlet pipe 204, condensed and purified by the condenser 205, and flows out. After the separation and purification are completed, the waste discharge valve 106 is opened to discharge the waste liquid from the waste discharge pipe 105.

[0029] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A separation and purification apparatus for the production of small molecule drugs, comprising a lid assembly for sealing the addition of raw materials and for condensation purification, characterized in that: It also includes a box assembly for holding raw materials and heating them at multiple points, wherein a stirring component for tumbling the raw materials to accelerate uniform evaporation is installed inside the box assembly, and the box cover assembly is installed on the top of the box assembly; The enclosure assembly includes a housing (101), which is provided with a heating mechanism for simultaneous heating from the bottom, side and center. A waste discharge pipe (105) is provided on one side of the bottom of the housing (101), and a waste discharge valve (106) is installed on the waste discharge pipe (105). The agitation assembly includes a drive roller (304) and a support roller (301). The drive roller (304) and the support roller (301) are symmetrically distributed vertically. A conveyor belt (302) is installed between the drive roller (304) and the support roller (301). Several agitation plates (303) are evenly distributed on the surface of the conveyor belt (302). A servo motor (305) is provided in front of the drive roller (304).

2. The separation and purification apparatus for small molecule drug production according to claim 1, characterized in that: The cover assembly includes a cover (201), a feed pipe (202) is provided on the cover (201), an exhaust pipe (204) is provided on one side of the feed pipe (202), and a condenser (205) is installed on the exhaust pipe (204).

3. The separation and purification apparatus for small molecule drug production according to claim 2, characterized in that: A sealing gasket (206) is affixed to the bottom surface of the chassis cover (201), and a sealing cap (203) is installed on the feed pipe (202).

4. The separation and purification apparatus for small molecule drug production according to claim 1, characterized in that: The heating mechanism includes a bottom heating plate (102), a side heating plate (103), and a center heating plate (104). The bottom heating plate (102) is installed on the bottom surface of the housing (101), the side heating plates (103) are installed on the two side walls of the housing (101), and the center heating plate (104) is installed in the middle of the housing (101) and passes through the ring formed by the conveyor belt (302).

5. The separation and purification apparatus for small molecule drug production according to claim 1, characterized in that: Two agitation components are provided, symmetrically distributed inside the casing (101), and tumbling towards the center from opposite sides.

6. The separation and purification apparatus for small molecule drug production according to claim 5, characterized in that: The active roller (304) and the support roller (301) are respectively connected to the sealed bearing of the housing (101), and the servo motor (305) is bolted to the housing (101).

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