Protein purification device

Abstract

The utility model relates to the technical field of protein purification and discloses a protein purification device which comprises a purification tank, a fixing frame is mounted on the outer surface of the purification tank, a cover body is mounted on the upper surface of the purification tank, a first feeding pipe, a second feeding pipe and a supporting frame are mounted on the upper surface of the cover body, and a discharging pipe is mounted on the lower surface of the purification tank. A motor is installed on the upper surface of the supporting frame, a through opening is formed in the upper surface of the cover body, a cylinder is rotationally connected into the through opening and is a single-side closed cylinder, a through hole is formed in the upper surface of the cylinder, a connecting piece is installed at the output end of the motor, a rotating rod is installed on the lower surface of the connecting piece, and the rotating rod is rotationally connected into the through hole. A cleaning assembly is arranged on the outer surface of the rotating rod, and an adjusting assembly is arranged on the outer surface of the connecting piece. According to the cleaning device, the cleaning component and the adjusting component are matched for use, so that a solution adhered to the inner wall of the purification tank can be removed, and a relatively good cleaning effect is achieved.

Description

TECHNICAL FIELD

[0001] The utility model relates to protein purification technical field, concretely is a protein purification device. BACKGROUND

[0002] Biological protein, also known as bioactive protein, active protein peptide, is the general term of different peptides from dipeptide to complex linear, ring structure of 25 natural amino acids in different composition and arrangement, which is a multifunctional compound derived from protein, and in order to increase the use effect of biology, it is necessary to use extraction method to purify biological protein, extraction method uses the different solubility of solute in mutually insoluble solvents, and the operation method of extracting solute from the solution composed of another solvent.

[0003] The utility model discloses a kind of extraction method biological protein purification devices with publication number "CN220245996U", mainly by fixed frame, purification tank, transmission rod, purification mechanism and stirring rod composition, the technical scheme of feeding and discharging speed is fast, labor cost is reduced, solvent and solution mixing efficiency is high, mixing is more thorough, improves the purification efficiency of biological protein.

[0004] The above-mentioned document discloses the following defects of the extraction method biological protein purification device: after the solution is discharged from the purification tank, the purification tank needs to be cleaned, and in the prior art, the inner wall of the purification tank is cleaned by injecting cleaning liquid into the purification tank. However, during the cleaning process, when the solution has high viscosity, the solution will adhere to the inner wall of the purification tank, which will prevent the cleaning liquid from effectively removing the solution adhering to the inner wall of the purification tank.

[0005] Therefore, the existing extraction method biological protein purification device does not have a good cleaning structure, and needs to be improved to provide a protein purification device. UTILITY MODEL CONTENTS

[0006] The utility model aims to provide a protein purification device to solve the problems raised in the background art.

[0007] To solve the above technical problems, the utility model is realized by the following technical solutions:

[0008] The utility model discloses a kind of protein purification devices, including purification tank, the outer surface of the purification tank is equipped with fixing frame, the upper surface of the purification tank is equipped with cover, the upper surface of the cover is equipped with first feed pipe, second feed pipe and support frame, the lower surface of the purification tank is equipped with discharge pipe, the upper surface of the support frame is equipped with motor, the upper surface of the cover is equipped with mouth, the inside rotation of the mouth is connected with barrel, the barrel is single-side closed cylinder, the upper surface of the barrel is equipped with through-hole, the output end of the motor is equipped with connecting piece, the lower surface of the connecting piece is equipped with rotating rod, the inside rotation of the rotating rod is connected in through-hole, the outer surface of the rotating rod is provided with cleaning assembly, the outer surface of the connecting piece is provided with adjusting assembly.

[0009] Further, the cleaning assembly includes a connecting frame, one end of the connecting frame is equipped with a baffle, the inside of the connecting frame is equipped with a guide rod, the outer surface of the guide rod is slidably connected with a stirring rod, the outer surface of the stirring rod is equipped with a mounting groove, the inside of the mounting groove is equipped with a cleaning scraper.

[0010] Further, the outer surface of the guide rod is sleeved with a spring, one end of the spring is mounted on the outer surface of the stirring rod, the other end of the spring is mounted on the outer surface of the connecting frame.

[0011] Further, the adjusting assembly includes a connecting block, the connecting block is mounted on the outer surface of the connecting piece, the upper surface of the connecting block is equipped with a threaded hole, the inside of the threaded hole is threadedly connected with a one-way screw rod, one end of the one-way screw rod penetrates the barrel and is equipped with a sliding block through a bearing, one end of the sliding block is hingedly connected with a connecting rod, the other end of the connecting rod is hingedly connected to the upper surface of the stirring rod.

[0012] Further, the upper surface of the one-way screw rod is equipped with a rotating handle.

[0013] Further, the outer surface of the rotating rod is equipped with a sliding groove, one end of the connecting block is provided with a limiting block, the limiting block is slidably connected inside the sliding groove.

[0014] The utility model has the following beneficial effects:

[0015] (1) The utility model discloses a rotating rotating handle, so that the rotating handle drives one-way screw rod to rotate, so that one-way screw rod moves upwards or downwards along the axial direction with threaded hole as the center, when one-way screw rod moves downwards, one-way screw rod pushes the sliding block to move downwards, in the process that the sliding block moves downwards, the sliding block pushes the stirring rod through the connecting rod, so that the stirring rod moves outside along the axial direction on the guide rod, and then make the cleaning scraper closely adhere to the inner wall of the purification tank, the solution adhered to the inner wall of the purification tank is removed by the cleaning scraper in the process that the motor rotates, and better cleaning effect is achieved.

[0016] Of course, any product implementing the present application does not necessarily need to achieve all the advantages mentioned above simultaneously. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed for the description of the embodiments will be briefly introduced. Obviously, the drawings described below are only some of the embodiments of the present application, and for those skilled in the art, other drawings can be obtained without creative labor on the basis of these drawings.

[0018] Figure 1 It is a schematic diagram of the overall structure of the present application.

[0019] Figure 2 It is a cross-sectional view of the overall structure of the present application.

[0020] Figure 3 It is a schematic diagram of the structure of the connecting piece, the rotating rod, the cleaning assembly and the adjusting assembly of the present application.

[0021] Figure 4 It is a schematic diagram of the structure of the connecting piece, the rotating rod and the adjusting assembly of the present application.

[0022] In the drawings, the component list represented by each reference numeral is as follows:

[0023] In the drawings, 1 is a purification tank, 2 is a fixing frame, 3 is a cover body, 4 is a first feeding pipe, 5 is a second feeding pipe, 6 is a supporting frame, 7 is a discharging pipe, 8 is a motor, 9 is a cylinder body, 10 is a connecting piece, 11 is a rotating rod, 1101 is a chute, 12 is a cleaning assembly, 1201 is a connecting frame, 1202 is a baffle, 1203 is a guide rod, 1204 is a stirring rod, 1205 is a mounting groove, 1206 is a cleaning scraper, 1207 is a spring, 13 is an adjusting assembly, 1301 is a connecting block, 1302 is a one-way screw rod, 1303 is a sliding block, 1304 is a connecting rod, 1305 is a rotating handle, and 1306 is a limiting block. DETAILED DESCRIPTION

[0024] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only some of the embodiments of the present application, not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0025] Please refer to Figure 1 - Figure 4As shown, the utility model is a kind of protein purification device, including purification tank 1, fixed frame 2 is installed on the outer surface of purification tank 1, cover body 3 is installed on the upper surface of purification tank 1, first feed pipe 4, second feed pipe 5 and support frame 6 are installed on the upper surface of cover body 3, discharge pipe 7 is installed on the lower surface of purification tank 1, motor 8 is installed on the upper surface of support frame 6, the upper surface of cover body 3 is provided with through mouth, the inside rotation of through mouth is connected with cylinder 9, cylinder 9 is single-side closed cylinder, the upper surface of cylinder 9 is provided with through hole, the output end of motor 8 is installed with connecting piece 10, the lower surface of connecting piece 10 is installed with rotating rod 11, rotating rod 11 is rotatably connected in the inside of through hole, the outer surface of rotating rod 11 is provided with cleaning assembly 12, the outer surface of connecting piece 10 is provided with adjusting assembly 13;

[0026] By the cooperation of cleaning assembly 12 and adjusting assembly 13, the solution adhered to the inner wall of purification tank 1 can be removed, and good cleaning effect is achieved.

[0027] The outer surface of discharge pipe 7 is installed with control valve;

[0028] Cleaning assembly 12 includes connecting frame 1201, baffle 1202 is installed at one end of connecting frame 1201, guide rod 1203 is installed in the inside of connecting frame 1201, stirring rod 1204 is slidably connected to the outer surface of guide rod 1203, mounting groove 1205 is formed in the outer surface of stirring rod 1204, cleaning scraper 1206 is installed in the inside of mounting groove 1205.

[0029] Spring 1207 is sleeved on the outer surface of guide rod 1203, one end of spring 1207 is installed on the outer surface of stirring rod 1204, the other end of spring 1207 is installed on the outer surface of connecting frame 1201.

[0030] Adjusting assembly 13 includes connecting block 1301, connecting block 1301 is installed on the outer surface of connecting piece 10, screw hole is formed in the upper surface of connecting block 1301, one-way screw 1302 is screw-connected in the inside of screw hole, one end of one-way screw 1302 penetrates cylinder 9 and is installed with sliding block 1303 through bearing, one end of sliding block 1303 is hinged with connecting rod 1304, the other end of connecting rod 1304 is hinged on the upper surface of stirring rod 1204.

[0031] Rotary handle 1305 is installed on the upper surface of one-way screw 1302.

[0032] Slotted 1101 is formed in the outer surface of rotating rod 11, limit block 1306 is arranged at one end of connecting block 1301, and limit block 1306 is slidably connected in the inside of slotted 1101.

[0033] In use, first, the first feeding pipe 4, the second feeding pipe 5 and the discharge pipe 7 are connected with external pipelines, in use, the solution and the solvent are injected into the interior of the purification tank 1 through the first feeding pipe 4 and the second feeding pipe 5, then the motor 8 is started, the output end of the motor 8 drives the connecting piece 10 and the rotating rod 11 to rotate, and the barrel 9 rotates in the opening, in the rotating process of the rotating rod 11, the stirring rod 1204 mixes the solution and the solvent in the purification tank 1, when the solution is mixed, the motor 8 is closed, the control valve is started, and the solution in the purification tank 1 is discharged from the purification tank 1 through the discharge pipe 7;

[0034] When the inner wall of the purification tank 1 needs to be cleaned, a certain amount of cleaning liquid is injected into the purification tank 1 through the first feeding pipe 4, then the rotating handle 1305 is rotated, the rotating handle 1305 drives the one-way screw rod 1302 to rotate, the one-way screw rod 1302 moves upwards or downwards along the axial direction with the threaded hole as the center, when the one-way screw rod 1302 moves downwards, the one-way screw rod 1302 drives the sliding block 1303 to move downwards, in the moving process of the sliding block 1303, the sliding block 1303 drives the stirring rod 1204 to move outwards along the axial direction on the guide rod 1203 through the connecting rod 1304, so that the cleaning scraper 1206 tightly abuts against the inner wall of the purification tank 1, then the motor 8 is started, the motor 8 drives the cleaning assembly 12 to rotate, and the cleaning scraper 1206 removes the solution adhered to the inner wall of the purification tank 1, so that a better cleaning effect is achieved.

[0035] The preferred embodiments disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details, and the utility model is not limited to the specific embodiments. Obviously, according to the content of the specification, many modifications and changes can be made. The specification selects and specifically describes these embodiments, in order to better explain the principle and practical application of the utility model, so that the person skilled in the art can well understand and utilize the utility model. The utility model is limited by the claims and the whole scope and equivalents.

Claims

1. A protein purification apparatus, comprising a purification tank (1), a fixing frame (2) mounted on the outer surface of the purification tank (1), a cover (3) mounted on the upper surface of the purification tank (1), a first feed pipe (4), a second feed pipe (5) and a support frame (6) mounted on the upper surface of the cover (3), a discharge pipe (7) mounted on the lower surface of the purification tank (1), and a motor (8) mounted on the upper surface of the support frame (6), characterized in that: The upper surface of the cover (3) is provided with an opening, and a cylinder (9) is rotatably connected inside the opening. The cylinder (9) is a single-sided closed cylinder, and a through hole is provided on the upper surface of the cylinder (9). The output end of the motor (8) is equipped with a connector (10), and a rotating rod (11) is installed on the lower surface of the connector (10). The rotating rod (11) is rotatably connected to the inside of the through hole. A cleaning component (12) is provided on the outer surface of the rotating rod (11), and an adjustment component (13) is provided on the outer surface of the connector (10).

2. The protein purification apparatus according to claim 1, characterized in that: The cleaning component (12) includes a connecting frame (1201), one end of which is equipped with a baffle (1202). A guide rod (1203) is installed inside the connecting frame (1201). A stirring rod (1204) is slidably connected to the outer surface of the guide rod (1203). An installation groove (1205) is opened on the outer surface of the stirring rod (1204). A cleaning scraper (1206) is installed inside the installation groove (1205).

3. The protein purification apparatus according to claim 2, characterized in that: A spring (1207) is fitted on the outer surface of the guide rod (1203). One end of the spring (1207) is installed on the outer surface of the stirring rod (1204), and the other end of the spring (1207) is installed on the outer surface of the connecting frame (1201).

4. The protein purification apparatus according to claim 1, characterized in that: The adjustment component (13) includes a connecting block (1301), which is installed on the outer surface of the connector (10). The upper surface of the connecting block (1301) is provided with a threaded hole, and a one-way screw (1302) is threaded inside the threaded hole. One end of the one-way screw (1302) passes through the cylinder (9) and a slider (1303) is installed through a bearing. One end of the slider (1303) is hinged to a connecting rod (1304), and the other end of the connecting rod (1304) is hinged to the upper surface of the stirring rod (1204).

5. The protein purification apparatus according to claim 4, characterized in that: A rotary handle (1305) is mounted on the upper surface of the one-way screw (1302).

6. The protein purification apparatus according to claim 5, characterized in that: The outer surface of the rotating rod (11) is provided with a sliding groove (1101), and one end of the connecting block (1301) is provided with a limiting block (1306), which is slidably connected inside the sliding groove (1101).

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