Humanized mouse syringe
By introducing a limiting groove and limiting block into the humanized mouse syringe, combined with electric heating and a stable connection, the problem of difficult needle insertion length control was solved, ensuring the accuracy and convenience of experimental results.
Patent Information
- Application Number
- CN202520251460.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Priority Date
- 2024-12-05
- Filing Date
- 2025-02-18
- Publication Date
- 2025-12-16
- Estimated Expiration
- 2035-02-18
AI Technical Summary
Existing syringes cannot effectively control the needle insertion length, resulting in inaccurate injection sites when injecting humanized mice, which affects experimental results, especially in young mice where the error is greater.
A humanized mouse syringe was designed, comprising a syringe barrel and a needle control assembly. The needle insertion length is precisely controlled by sliding a limiting cylinder on the cannula and utilizing the cooperation of a limiting groove and a limiting block. At the same time, an electric heating wire is set inside the syringe barrel to ensure that the liquid reaches the predetermined temperature. An external transparent plate and scale lines are used to observe and control the injection volume. A convex ring and a baffle are designed on the outer wall to improve grip stability.
It enables precise control of the needle insertion length, ensuring the accuracy of experimental results, and improves the ease of operation of the syringe and the reliability of the experiment by heating the drug solution and stabilizing the needle connection.
Smart Images
Figure CN223668112U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to humanized mouse experimental technology field especially, a kind of humanized mouse injector. BACKGROUND
[0002] The way of injecting reagent to experimental animal has been used for a long time, and the animal model has been used for a long time in medical field for research and use, and in many experiments, mice are used for experiment, and the experiment of humanized mouse is also continuously carried out.
[0003] In the experiment, a certain amount of stem cells need to be injected into immunodeficient mice to construct humanized mice, and the required needle insertion length is different according to the experimental requirements (distance to liver or spleen), but the current injector cannot control the needle insertion length, which affects the injection site and the state of the mouse, and affects the test results, especially for young mice, the error is larger. Therefore, a new technical scheme is needed to solve at least one of the above technical problems. SUMMARY
[0004] In view of the above, the utility model aims to provide a kind of humanized mouse injector, solve the injector for humanized mouse, when liver injection is carried out to mouse, the problem that needle insertion length is not easy to control, affects experimental result.
[0005] In order to realize the above technical purpose, reach the above technical requirement, the technical scheme that the utility model employs is:
[0006] A kind of humanized mouse injector, comprising:
[0007] The needle cylinder has a connecting tube at one end and an opening at the other end, a piston rod is movably inserted in the needle cylinder, and a needle is inserted in the connecting tube in communication;
[0008] The needle control assembly includes a sleeve disposed on the needle cylinder and surrounding the connecting tube, a limiting cylinder is slidably disposed on the sleeve, a sliding groove is formed on the outer surface of one side of the needle cylinder, a plurality of limiting grooves are arrayed on the inner wall of one side of the sliding groove, a sliding plate is connected to the limiting cylinder and slidably inserted in the sliding groove, a plug-in slot is formed in the sliding plate, and a limiting block is movably inserted in the plug-in slot and in plug-in cooperation with the limiting groove.
[0009] As a preferred technical scheme, the outer surface of the sleeve is provided with an annular embedding groove, one end of the limiting cylinder is provided with a limiting ring, and a limiting spring is installed between the limiting ring and the inner wall of the annular embedding groove.
[0010] As a preferred technical scheme, the limiting block is provided with a supporting plate, and anti-skid lines are arranged in an array on the supporting plate.
[0011] As a preferred technical scheme, the needle cylinder is provided with a cavity, and an electric heating wire is arranged in the cavity.
[0012] As a preferred technical scheme, a groove is formed in the inner wall of the connecting pipe, a sealing ring is arranged in the groove, the insertion end of the needle is inserted into the groove and presses the sealing ring, a clamping groove is formed in the inner wall of the groove, and the insertion end of the needle is provided with a clamping block matched with the clamping groove.
[0013] As a preferred technical scheme, the outer wall of the needle cylinder is provided with a transparent plate, and scale lines are arranged on the transparent plate.
[0014] As a preferred technical scheme, the outer wall of the needle cylinder is arranged with a plurality of convex rings in an array.
[0015] As a preferred technical scheme, the needle cylinder is provided with a blocking cylinder at one end close to the opening, and a blocking block is arranged on the blocking cylinder.
[0016] Compared with the traditional technical scheme, the utility model has the beneficial effects that:
[0017] 1) The sleeve is arranged on the needle cylinder, the limiting cylinder is sleeved on the sleeve and slides, the limiting cylinder is used for contacting the mouse limbs to limit the needle insertion length, three limiting grooves are arranged, the sliding plate drives the limiting cylinder to move, the limiting block is inserted into different limiting grooves, and the actual position of the limiting cylinder is controlled, so that the needle insertion length can be effectively controlled when the mouse is injected, and the accuracy of experimental results is ensured.
[0018] 2) The cavity is arranged in the needle cylinder, the electric heating wire is arranged in the cavity, the electric heating wire is electrified to heat the liquid medicine when the liquid medicine is arranged in the needle cylinder, the heating temperature is controlled by the control panel, the liquid medicine is heated to a predetermined temperature, and the accuracy of experimental results is ensured. BRIEF DESCRIPTION OF DRAWINGS
[0019] Figure 1 is a perspective view of the syringe provided by an embodiment of the utility model;
[0020] Figure 2 is a perspective view of the syringe provided by an embodiment of the utility model;
[0021] Figure 3 is a partial perspective view of the syringe provided by an embodiment of the utility model;
[0022] Figure 4 is a partial perspective view of the syringe provided by an embodiment of the utility model;
[0023] Figure 5 is an exploded view of the syringe provided by an embodiment of the utility model;
[0024] Figure 6 is a perspective view of the needle provided by an embodiment of the utility model;
[0025] Figure 7 is Figure 1 is an enlarged view of the local part A;
[0026] Figure 8 is Figure 2 is an enlarged view of the local part B;
[0027] Figure 9 is Figure 4 is an enlarged view of the local part C.
[0028] in Figures 1-9 , 1, needle cylinder; 2, connecting pipe; 3, piston rod; 4, needle; 5, needle control assembly; 6, annular embedding groove; 7, limiting spring; 8, support plate; 9, cavity; 10, electric heating wire; 11, recess; 12, sealing ring; 13, clamping groove; 14, clamping block; 15, transparent plate; 16, convex ring; 17, blocking cylinder; 18, blocking block; 501, sleeve; 502, limiting cylinder; 503, sliding groove; 504, limiting groove; 505, sliding plate; 506, plug-in groove; 507, limiting block. DETAILED DESCRIPTION
[0029] The utility model is further described below in combination with the drawings.
[0030] In the drawings of the embodiments of the utility model, same or similar signs correspond to same or similar parts; in the description of the utility model, it is understood that if the terms "top", "bottom", "left", "right", "front", "back", "inner", "outer" and the like appear, the orientation or position relationship is based on the orientation or position relationship shown in the drawings, and is only for the convenience of describing the utility model, and does not indicate or imply that the indicated device or element must have a particular orientation, a particular orientation and operation, therefore the terms describing position relationship in the drawings are only used for example, and can not be understood as the limitation of the patent, and for the ordinary skilled person in the art, the specific meaning of the above terms can be understood according to the specific situation.
[0031] Please refer to Figures 1-9 , an embodiment of the utility model provides a kind of humanized mouse syringe, including needle cylinder 1 and needle control assembly 5, needle cylinder 1 one end has connecting pipe 2, other end is open, piston rod 3 is movably inserted in needle cylinder 1, needle 4 is inserted in connecting pipe 2 and is communicated, liquid medicine is placed in needle cylinder 1, by pressing piston rod 3, to push liquid medicine from needle 4 and be ejected, to complete injection.
[0032] The needle control assembly 5 comprises a sleeve 501 arranged on the needle cylinder 1 and surrounding the connecting pipe 2, a limiting cylinder 502 is slidingly arranged on the sleeve 501, and the end of the limiting cylinder 502 is used for contacting the mouse, and a sliding groove 503 is arranged on the outer surface of one side of the needle cylinder 1, and a plurality of limiting grooves 504 are arranged on the inner wall of one side of the sliding groove 503.
[0033] Further, the number of the limiting grooves 504 is three, which are divided into three gears, the limiting cylinder 502 is connected with a sliding plate 505 which is slidingly inserted into the sliding groove 503, a plug-in groove 506 is arranged in the sliding plate 505, a limiting block 507 which is in plug-in cooperation with the limiting grooves 504 is movably inserted into the plug-in groove 506, preferably, as shown in Figure 5 and Figure 7 The plug-in groove 506 has two notches, the limiting block 507 is configured as an L-shaped block which has two ends and the two ends are movably penetrated through the two notches respectively, when the sliding plate 505 slides along the sliding groove 503, the limiting cylinder 502 can slide along the sleeve 501, before injecting the mouse, the sliding plate 505 is first slid to drive the limiting cylinder 502 to slide, when the sliding plate 505 is slid to make the limiting block 507 align with one of the limiting grooves 504, the limiting block 507 is transversely slid to make the limiting block 507 slidingly inserted into the limiting groove 504, so as to fix the sliding plate 505 and realize the fixation of the limiting cylinder 502, which limits the sliding of the limiting cylinder 502, then the needle cylinder 1 is held to stab the needle 4 into the mouse, during the stabbing process, the limiting cylinder 502 contacts the mouse limb, so as to limit the needle 4 from continuously stabbing, by arranging a plurality of limiting grooves 504, the limiting block 507 on the sliding plate 505 is inserted into the limiting grooves 504 at different positions, so as to control the position of the limiting cylinder 502, the limiting cylinder 502 contacts the mouse limb to limit the penetration length of the needle 4, the limiting cylinder 502 at different positions can control different penetration lengths.
[0034] As shown in Figures 1-9 The sleeve 501 is arranged on the needle cylinder 1, the limiting cylinder 502 is slidingly arranged on the sleeve 501, the limiting cylinder 502 is used for contacting the mouse limb to limit the penetration length of the needle 4, by arranging three limiting grooves 504, the three limiting grooves 504 can be used as three gears of commonly used penetration lengths, the sliding plate 505 drives the limiting cylinder 502 to move, the limiting block 507 is inserted into the limiting grooves 504 at different positions, so as to control the actual position of the limiting cylinder 502, so as to effectively control the penetration length when injecting the mouse, and ensure the accuracy of the experimental results.
[0035] As shown in Figure 8As shown, the outer surface of the sleeve 501 is provided with an annular groove 6, one end of the limiting cylinder 502 is provided with a limiting ring, and a limiting spring 7 is arranged between the limiting ring and the inner wall of the annular groove 6. In the initial state (when the limiting block 507 is not inserted into the limiting groove 504), the limiting cylinder 502 is completely sleeved on the sleeve 501 under the elastic resistance of the limiting spring 7. When the sliding plate 505 adjusts the position of the limiting cylinder 502, the limiting cylinder 502 will press the limiting spring 7, and when the limiting block 507 is inserted into any one of the limiting grooves 504, the limiting spring 7 is also in a compressed state. When the limiting block 507 is withdrawn from the limiting groove 504, the sliding plate 505 is reset under the elastic resistance of the limiting spring 7, thereby automatically completely sleeving the limiting cylinder 502 on the sleeve 501, so as to reset the gear from zero and facilitate subsequent adjustment and use.
[0036] As shown in Figure 5 and Figure 7 , the limiting block 507 is provided with a supporting plate 8, and the supporting plate 8 is arrayed with anti-skid lines. By providing the supporting plate 8 on the limiting block 507 and constructing the anti-skid lines, it is convenient to move the limiting block 507 by the thumb during use, thereby improving the convenience during adjustment.
[0037] As shown in Figure 2 , the needle cylinder 1 is provided with a cavity 9, and the cavity 9 is provided with an electric heating wire 10. Preferably, the outer surface of the needle cylinder 1 is provided with a control panel and a connecting head connected with the electric heating wire 10. The connecting head can connect the electric heating wire 10 with an external power supply through a wire to be electrified. When the needle cylinder 1 contains a liquid medicine, the electric heating wire 10 is electrified to heat the liquid medicine, and the heating temperature is controlled by the control panel, so as to heat the liquid medicine to a predetermined temperature, thereby ensuring the accuracy of the experimental results.
[0038] As shown in Figure 6 , Figure 8 and Figure 9 , the inner wall of the connecting pipe 2 is provided with a groove 11, and the groove 11 is provided with a sealing ring 12. The insertion end of the needle 4 is inserted into the groove 11 and presses the sealing ring 12. The inner wall of the groove 11 is provided with a clamping groove 13, and the insertion end of the needle 4 is provided with a clamping block 14 matched with the clamping groove 13. Preferably, as shown in Figure 9The card slot 13 includes a vertical slot and a transverse arc-shaped slot connected therewith. When installing the needle 4, first, the insertion part of the needle 4 is inserted into the groove 11 in alignment, and then the clamping block 14 is inserted into the vertical slot, and then the needle 4 is rotated, and the clamping block 14 is slid from the vertical slot into the transverse arc-shaped slot. At this time, the insertion part of the needle 4 extrudes the sealing ring 12, and the sealing ring 12 applies an elastic counteracting force to the needle 4, and cooperates with the clamping of the transverse arc-shaped slot to achieve the effect of stably inserting the needle 4 into the connecting pipe 2. Not only does this ensure the stability of the connection, but also improves the sealing effect between the two. When inserting, only vertical insertion and horizontal rotation are required, and installation or removal is relatively convenient.
[0039] As shown in Figure 1 and Figure 3 , the outer wall of the needle cylinder 1 is provided with a transparent plate 15, and the transparent plate 15 is provided with scale lines. Through the transparent plate 15 and the scale lines, the injection of the medicine can be observed, and the injection amount of the medicine can be controlled, thereby improving the practicability.
[0040] As shown in Figure 1 and Figure 3 , the outer wall of the needle cylinder 1 is arrayed with a plurality of convex rings 16. Through the plurality of convex rings 16, the friction force of holding with the palm is increased, and the holding is more stable.
[0041] As shown in Figure 1 and Figure 3 , the needle cylinder 1 is provided with a blocking cylinder 17 near one end of the opening, and the blocking cylinder 17 is provided with a blocking block 18. Through the blocking cylinder 17 and the blocking block 18, the operation can be completed with one hand when injecting the medicine, thereby improving the convenience.
[0042] Any numerical values recited herein include all values from lower to upper bounds with increments of one unit between them, provided that there is a separation of at least two units between any lower value and any higher value. As an example, if a numerical value, for example, the number of parts or process variables (e.g., temperature, pressure, time, etc.) is stated to be from 1 to 90, preferably from 20 to 80, more preferably from 30 to 70, it is intended that values such as 15 to 85, 22 to 68, 43 to 51, 30 to 32, etc. are expressly enumerated in this specification. For values which are less than one, one unit is considered to be 0.0001, 0.001, 0.01, 0.1, as appropriate. These are only examples of what is specifically enumerated herein, and the enumeration of numbers from the lower to the upper bounds is not to be construed as being limited to the enumerated values itself reciting the lower and upper bounds, but rather is meant to be a short hand representation of the meaning of the phrase ranging between the numbers.
[0043] Unless otherwise stated, all ranges include the endpoints and all numbers between them. The terms "approximately" or "about" used with ranges apply to both endpoints of the range. Thus, "approximately 20 to 30" is intended to cover "approximately 20 to approximately 30," including at least the specified endpoints.
[0044] All articles and references disclosed herein, including patent applications and publications, are incorporated herein by reference for various purposes. The term “substantially constitutes…” used to describe a combination should include the identified elements, components, parts, or steps, as well as other elements, components, parts, or steps that do not substantially affect the essential novelty of the combination. The use of the terms “comprising” or “including” to describe combinations of elements, components, parts, or steps herein also contemplates embodiments substantially constituted by such elements, components, parts, or steps. The use of the term “may” herein is intended to indicate that any described attribute included by “may” is optional.
[0045] Multiple elements, components, parts, or steps can be provided by a single integrated element, component, part, or step. Alternatively, a single integrated element, component, part, or step can be divided into multiple separate elements, components, parts, or steps. The use of "a" or "an" to describe an element, component, part, or step does not imply the exclusion of other elements, components, parts, or steps.
[0046] It should be understood that the above description is for illustrative purposes and not for limitation. Many embodiments and applications beyond the provided examples will be apparent to those skilled in the art upon reading the above description. Therefore, the scope of this teaching should not be determined by reference to the above description, but rather by reference to the appended claims and the full scope of their equivalents. For purposes of completeness, all articles and references, including patent applications and publications, are incorporated herein by reference. The omission of any aspect of the subject matter disclosed herein in the preceding claims is not intended as a waiver of that subject matter, nor should it be construed as an indication that the inventors have not considered that subject matter as part of the disclosed utility model subject matter.
Claims
1. A humanized mouse syringe, characterized in that, Include: The needle cylinder has a connecting pipe at one end and an opening at the other end, a piston rod is movably inserted in the needle cylinder, and a needle is inserted in the connecting pipe; The needle control assembly includes a sleeve arranged on the needle cylinder and surrounding the connecting pipe, a limiting cylinder is slidingly arranged on the sleeve, a sliding groove is formed on one side of the outer surface of the needle cylinder, a plurality of limiting grooves are arrayed on one side of the inner wall of the sliding groove, a sliding plate is slidingly inserted in the sliding groove at the end of the limiting cylinder, a plug-in groove is formed in the sliding plate, and a limiting block is movably inserted in the plug-in groove at the end of the limiting groove.
2. The humanized mouse syringe of claim 1, wherein, The outer surface of the sleeve is provided with an annular embedding groove, and the limiting cylinder is provided with a limiting ring at one end, and a limiting spring is installed between the limiting ring and the inner wall of the annular embedding groove.
3. The humanized mouse syringe of claim 1, wherein, The limiting block is provided with a support plate, and the support plate is arrayed with anti-skid lines.
4. The humanized mouse syringe of claim 1, wherein, A cavity is formed in the needle cylinder, and an electric heating wire is arranged in the cavity.
5. The humanized mouse syringe of claim 1, wherein, A recess is formed in the inner wall of the connecting pipe, a sealing ring is arranged in the recess, the plug-in end of the needle is inserted in the recess and presses the sealing ring, a clamping groove is formed in the inner wall of the recess, and the plug-in end of the needle is provided with a clamping block which is clamped and matched with the clamping groove.
6. The humanized mouse syringe of claim 1, wherein, The outer wall of the needle cylinder is provided with a transparent plate, and the transparent plate is provided with a scale line.
7. The humanized mouse syringe of claim 1, wherein, The outer wall of the needle cylinder is arrayed with a plurality of convex rings.
8. The humanized mouse syringe of claim 1, wherein, The end of the needle cylinder close to the opening is provided with a blocking cylinder, and the blocking cylinder is provided with a blocking block.