Detection device for dissolved oxygen in injection preparation process

Abstract

The utility model relates to the technical field of detection instruments, in particular to a detection device for dissolved oxygen in an injection preparation process, which comprises a detection box, a rotating door rotationally arranged at the top of the detection box, a stirring mechanism, a stirring blade and a detection winding mechanism, wherein the stirring mechanism is arranged on the inner side of the detection box; the stirring blades are arranged on the outer side of the stirring mechanism; and the detection winding mechanism is arranged on the detection box. Through the arrangement of the stirring mechanism, the motor can drive the stirring blades to rotate while rotating and stirring through the bevel gear I and the bevel gear II, so that dissolved oxygen in a solvent can be ensured to be uniformly distributed, the situation that the concentration of local dissolved oxygen is too high or too low is avoided, and the accuracy of dissolved oxygen detection is improved; and the exchange speed of the solvent and oxygen in the air is accelerated, so that the oxygen can be dissolved in the solvent more quickly, the detection can be completed in a shorter time, and the detection efficiency is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to detection instrument technical field especially, relate to a kind of detection device of injection preparation process dissolved oxygen. BACKGROUND

[0002] In the production process of injection, drug oxidation is an important influencing factor. Oxygen and drug can form peroxide compounds, leading to drug deterioration. Especially under the catalysis of humid air and light, oxidation reaction will accelerate, thereby affecting the stability and shelf life of the drug. Oxidative degradation of drug substances in pharmaceutical preparations not only reduces drug efficacy, but also can produce adverse pharmacological effects, including toxic or negative side effects. Therefore, strict detection of dissolved oxygen in injection is a key step to ensure drug quality.

[0003] The Chinese patent with publication number CN210570810U discloses a detection device for dissolved oxygen in liquid, comprising a tube body, a test connector, a circuit board, a sensor module, and a protective cover. The sensor module is fitted outside the circuit board and is used to detect the AD value and temperature value of the oxygen content in the measured liquid. The circuit board includes an AD / DA converter and a microcontroller. The microcontroller is used to control the sensor module to detect the AD value and temperature value of the oxygen content in the measured liquid, calculate and process the AD value and temperature value of the oxygen content, and control the AD / DA converter to convert and output the calculated and processed AD value and temperature value of the oxygen content. This scheme improves the accuracy and efficiency of the detection device's oxygen content detection through high-precision oxygen content and temperature detection by the sensor module, microcontroller calculation and processing, and double-channel AD / DA converter sampling and conversion output.

[0004] However, the above-mentioned disclosed scheme has the following disadvantages: the existing detection device for dissolved oxygen in the injection preparation process cannot fully stir the dissolved oxygen and solvent, which affects the detection effect, and cannot protect the detector after detection, which easily affects the service life of the detector. UTILITY MODEL CONTENT

[0005] The utility model aims at the problem of insufficient mixing of dissolved oxygen and solvent and winding of the detector in the background art, and provides a detection device for dissolved oxygen in the injection preparation process.

[0006] The technical scheme of the utility model: a detection device for dissolved oxygen in the injection preparation process, comprising a detection box and a rotating door rotatingly arranged on the top of the detection box; further comprising:

[0007] A stirring mechanism is arranged inside the detection box and is used to rotate and self-rotate to mix the preparation agent and dissolved oxygen.

[0008] The stirring blade is arranged on the outside of the stirring mechanism, a plurality of the stirring blades are arranged annularly around the stirring mechanism, and the end of the stirring blade away from the stirring mechanism is in contact with the inside of the detection box;

[0009] The detection winding mechanism is arranged on the detection box and is used for controlling the winding and unwinding of the detector.

[0010] Preferably, the stirring mechanism comprises a motor, a rotating shaft I, a connecting ring and a rotation component;

[0011] The motor is arranged on the top of the detection box, the rotating shaft I is arranged on the output end of the motor, and the connecting ring is arranged on the outside of the rotating shaft I;

[0012] The rotation component is arranged on the outside of the rotating shaft I and is used for driving the stirring blade to rotate.

[0013] Preferably, the rotation component comprises a bevel gear I, a connecting rod I and a connecting shaft;

[0014] The bevel gear I is arranged on the outside of the rotating shaft I, the connecting rod I is arranged on the bottom of the bevel gear I, the connecting shaft is rotatably arranged on the outside of the connecting ring, the outside of the connecting shaft is provided with a bevel gear II, and the bottom of the connecting rod I is rotatably provided with a connecting rod II.

[0015] Preferably, the detection winding mechanism comprises a winding component and a limiting component;

[0016] The winding component is arranged on the detection box and is used for winding and unwinding the detector;

[0017] The limiting component is arranged on the outside of the detection box and is used for fixing the position of the winding component.

[0018] Preferably, the winding component comprises a sliding groove, a sliding ring, a shielding plate, a detection head and a rotating shaft II;

[0019] The sliding groove is arranged on the detection box, the sliding ring is slidably arranged on the inside of the sliding groove, the detection head is arranged on the end of the sliding groove, the shielding plate is symmetrically arranged on the upper and lower sides of the sliding ring, the rotating shaft II is rotatably arranged on the detection box, the end of the rotating shaft II is provided with a rotating ring, the side surface of the rotating ring is limited by a limiting wheel, and the outside of the rotating shaft II is provided with a winding roller.

[0020] Preferably, the limiting component comprises a limiting rod, a fixed shaft and a spring;

[0021] The fixed shaft is arranged on the outside of the detection box, the limiting rod is arranged on the outside of the fixed shaft, the spring is arranged on the end of the limiting rod, and the end of the spring away from the limiting rod is provided with a fixed plate.

[0022] Compared with the prior art, the utility model has the beneficial technical effects that:

[0023] 1. Through the setting of the stirring mechanism, the motor can drive the stirring blade to rotate and self-rotate at the same time through bevel gear one and bevel gear two, which can ensure that the dissolved oxygen in the solvent is uniformly distributed, avoid the situation that the local dissolved oxygen concentration is too high or too low, thereby improving the accuracy of dissolved oxygen detection, speeding up the exchange speed of the solvent and oxygen in the air, making the oxygen dissolve into the solvent faster, enabling the detection to be completed in a shorter time, improving the detection efficiency, and ensuring that the flow of the solvent in the detection area is more uniform, reducing the error caused by uneven flow.

[0024] 2. Through the setting of the detection winding mechanism, the rotating ring drives the winding and unwinding of the wire, and can drive the detection head to move to control the detection state of the device, the cooperation of the rotating wheel and the limiting rod can make the detection head stop at any position, so that the wire can be neatly stored when not needed, avoiding the disorder of the wire, improving the neatness and safety of the working area, and enabling the detection personnel to accurately place the detection head in a specific position in the solvent as needed, thereby obtaining more accurate dissolved oxygen data. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 It is a structural schematic view of an embodiment of the utility model;

[0026] Figure 2 It is a structural schematic view of an embodiment of the utility model; Figure 1

[0027] Figure 3 It is a structural schematic view of an embodiment of the utility model;

[0028] Figure 4 It is an enlarged schematic view of A in the embodiment; Figure 3

[0029] Figure 5 It is a structural schematic view of the detection winding mechanism;

[0030] Figure 6 It is an enlarged schematic view of B in the embodiment. Figure 5

[0031] Reference signs: 1, detection box; 2, rotating door; 3, connecting block; 4, display screen; 501, motor; 502, rotating shaft one; 503, connecting rod one; 504, bevel gear one; 505, connecting ring; 506, connecting shaft; 507, bevel gear two; 508, stirring blade; 509, connecting rod two; 601, sliding groove; 602, sliding ring; 603, shielding plate; 604, detection head; 605, rotating shaft two; 606, rotating ring; 607, limiting rotating wheel; 608, winding roller; 609, limiting rod; 610, fixed shaft; 611, spring; 612, fixed plate. DETAILED DESCRIPTION​​​

[0032] Embodiment one

[0033] As Figures 1-4 shown, the utility model provides a kind of detection device of dissolved oxygen in injection preparation process, including detection box 1, the rotary door 2 of rotation being provided at the top of detection box 1, the connecting block 3 being provided at the outside of detection box 1, the display screen 4 being provided at the end of connecting block 3 away from detection box 1, stirring mechanism, stirring blade 508 and detection winding mechanism:

[0034] Stirring mechanism is arranged in the inside of detection box 1, for rotating stirring is self-rotating to mix preparation agent and dissolved oxygen simultaneously;

[0035] Stirring blade 508 is arranged outside stirring mechanism, and a plurality of stirring blade 508 are annularly arranged around stirring mechanism, and the end of stirring blade 508 away from stirring mechanism is in contact with the inside of detection box 1.

[0036] Detection winding mechanism is arranged on detection box 1, for controlling the convergence and release of detector.

[0037] Stirring mechanism includes motor 501, shaft one 502, connecting ring 505 and self-rotating assembly;Motor 501 is arranged at the top of detection box 1, shaft one 502 is arranged at the output end of motor 501, connecting ring 505 is arranged outside shaft one 502, motor 501 is started, and motor 501 drives shaft one 502 to rotate, and shaft one 502 drives connecting ring 505 to rotate;Self-rotating assembly is arranged outside shaft one 502, for driving stirring blade 508 to self-rotate. Self-rotating assembly includes bevel gear one 504, connecting rod one 503 and connecting shaft 506;Bevel gear one 504 is arranged outside shaft one 502, and bevel gear one 504 is symmetrically arranged two about shaft one 502, and is located at the bottom of connecting ring 505, connecting rod one 503 is arranged at the bottom of bevel gear one 504, connecting shaft 506 is rotatably arranged outside connecting ring 505, and connecting shaft 506 is annularly arranged three around connecting ring 505, bevel gear two 507 is arranged outside connecting shaft 506, the side surface of bevel gear two 507 is fixedly connected with the end portion of stirring blade 508, the bottom of bevel gear two 507 is engaged with the side surface of bevel gear one 504, and the bottom of connecting rod one 503 is rotatably provided with connecting rod two 509, the end of connecting rod two 509 away from connecting rod one 503 is connected with the inner wall of detection box 1, shaft one 502 drives bevel gear one 504 to rotate, bevel gear one 504 drives bevel gear two 507 to rotate, and bevel gear two 507 drives stirring blade 508 to self-rotate through connecting shaft 506, while connecting ring 505 drives stirring blade 508 to rotate around shaft one 502 through connecting shaft 506, so that the configuration agent and dissolved oxygen in detection box 1 are mixed.

[0038] Example Two

[0039] As Figures 5-6 shown, the utility model discloses a kind of detection device of dissolving oxygen in injection preparation process, compared with example one, the structure of the detection winding mechanism is introduced in detail in the present embodiment.

[0040] Detection winding mechanism includes winding component and limiting component;Winding component is set on detection box 1, for the collection of detector and release;Limiting component is set on the outside of detection box 1, for the position of winding component is advanced fixed.Winding component includes chute 601, sliding ring 602, baffle 603, detection head 604 and pivot two 605;Chute 601 is set on detection box 1, sliding ring 602 is slidably arranged on the inside of chute 601, detection head 604 is set on the end of chute 601, baffle 603 is symmetrically set on the upper and lower sides of sliding ring 602, the length of each baffle 603 and chute 601 is same, the top of detection box 1 is provided with notch, the shape of notch and baffle 603 is same, so baffle 603 can pass through detection box 1, detection head 604 is provided with socket, display screen 4 is also provided with jack, and the two ends of wire are clamped in socket and jack, so as to connect detection head 604 and display screen 4, so as to detect solvent and display detection result on display screen 4, pivot two 605 is rotatably arranged on detection box 1, the end of pivot two 605 is provided with rotating ring 606, the side of rotating ring 606 is limited by limit wheel 607, the outside of pivot two 605 is provided with winding roller 608, the outside of winding roller 608 is provided with helical blade, the outside of wire is clamped on helical blade, when needing to detect, rotating ring 606 is rotated clockwise, rotating ring 606 drives winding roller 608 to rotate, winding roller 608 releases the wire that is wound, so that detection head 604 moves downward, baffle 603 covers chute 601 during moving, keep the closed state of detection box 1, after detection, rotating ring 606 is rotated counterclockwise, so as to wind wire on the helical blade of winding roller 608.Limiting component includes limiting rod 609, fixed shaft 610 and spring 611;Fixed shaft 610 is set on the outside of detection box 1, limiting rod 609 is set on the outside of fixed shaft 610, spring 611 is set on the end of limiting rod 609, the end of spring 611 away from limiting rod 609 is provided with fixed plate 612, the end of fixed plate 612 is connected with the outside of detection box 1, limiting rod 609 and limit wheel 607 are located on the same plane, the outside of limit wheel 607 is provided with a plurality of convex corners, a notch is formed between every two convex corners, the shape of limiting rod 609 and notch is same, so limiting rod 609 can be clamped between notch, when limit wheel 607 rotates clockwise, limiting rod 609 does not affect rotation, when rotating counterclockwise, limiting rod 609 limits rotation, to guarantee the position of limit wheel 607 fixed.

[0041] In summary, in use, the rotating door 2 is opened, the dissolved oxygen and the solvent are all poured into the detection box 1, then one end of the electric wire is inserted into the jack of the display screen 4, and the electric wire is wound on the spiral blade of the winding roller 608, then the other end of the electric wire is inserted into the socket of the detection head 604, after the connection is completed, the rotating ring 606 is rotated clockwise, the rotating ring 606 drives the winding roller 608 to rotate, the winding roller 608 releases the wound electric wire, so that the detection head 604 moves downwards and is inserted into the solvent for detection, meanwhile, the limiting rod 609 is clamped on the limiting rotating wheel 607 to limit the position of the rotating wheel, then the motor 501 is started, the motor 501 drives the rotating shaft one 502 to rotate, the rotating shaft one 502 drives the bevel gear one 504 to rotate, the bevel gear one 504 drives the bevel gear two 507 to rotate, the bevel gear two 507 drives the stirring blade 508 to rotate through the connecting shaft 506, meanwhile, the connecting ring 505 drives the stirring blade 508 to rotate around the rotating shaft one 502 through the connecting shaft 506, so that the configuration agent and the dissolved oxygen in the detection box 1 are mixed, the display screen 4 displays the detection result in real time, after the detection is completed, the rotating ring 606 is rotated counterclockwise, so that the electric wire is gathered on the spiral blade of the winding roller 608, and the electric wire is protected.

[0042] The embodiments of the utility model are described in detail above in combination with the drawings, but the utility model is not limited to this, various changes can be made within the knowledge range possessed by the technical personnel in the technical field, without departing from the purpose of the utility model.

Claims

1. A device for detecting dissolved oxygen in injection preparation process, comprising a detection box (1) and a rotating door (2) rotatably arranged on the top of the detection box (1); characterized in that, Also include: Stirring mechanism, stirring mechanism is arranged in the inside of detection box (1), for rotating stirring while self-rotation to mix with preparation and dissolved oxygen; Stirring blade (508), stirring blade (508) is arranged outside the stirring mechanism, stirring blade (508) is annularly arranged with multiple around the stirring mechanism, and the end of stirring blade (508) away from the stirring mechanism is in contact with the inside of detection box (1); And detection winding mechanism, detection winding mechanism is arranged on detection box (1), for controlling the collection and release of detector.

2. The apparatus for detecting dissolved oxygen in an injection formulation process according to claim 1, wherein The stirring mechanism includes motor (501), shaft one (502), connecting ring (505) and self-rotation assembly; Motor (501) is arranged on the top of detection box (1), shaft one (502) is arranged on the output end of motor (501), connecting ring (505) is arranged outside shaft one (502); Self-rotation assembly is arranged outside shaft one (502), for driving stirring blade (508) to self-rotate.

3. The apparatus for detecting dissolved oxygen in a process for formulating an injectable according to claim 2, wherein The self-rotation assembly includes bevel gear one (504), connecting rod one (503) and connecting shaft (506); Bevel gear one (504) is arranged outside shaft one (502), connecting rod one (503) is arranged at the bottom of bevel gear one (504), connecting shaft (506) is rotatably arranged outside connecting ring (505), and connecting rod two (509) is rotatably arranged at the bottom of connecting rod one (503).

4. The apparatus for detecting dissolved oxygen in a process for formulating an injection according to claim 1, wherein The detection winding mechanism includes winding assembly and limiting assembly; Winding assembly is arranged on detection box (1), for collecting and releasing the detector; The limiting assembly is arranged outside the detection box (1), for fixing the position of the winding assembly.

5. The apparatus for detecting dissolved oxygen in a process solution for injection formulation according to claim 4, wherein The winding assembly includes sliding groove (601), sliding ring (602), shielding plate (603), detection head (604) and shaft two (605); Sliding groove (601) is arranged on detection box (1), sliding ring (602) is slidably arranged inside sliding groove (601), detection head (604) is arranged at the end of sliding groove (601), shielding plate (603) is symmetrically arranged on the upper and lower sides of sliding ring (602), shaft two (605) is rotatably arranged on detection box (1), and rotating ring (606) is arranged at the end of shaft two (605), limiting rotating wheel (607) is arranged on the side of rotating ring (606), and winding roller (608) is arranged outside shaft two (605).

6. The apparatus for detecting dissolved oxygen in a process solution for injection formulation according to claim 4, wherein The limiting assembly includes limiting rod (609), fixed shaft (610) and spring (611); Fixed shaft (610) is arranged outside the detection box (1), limiting rod (609) is arranged outside fixed shaft (610), spring (611) is arranged at the end of limiting rod (609), and fixed plate (612) is arranged at the end of spring (611) away from limiting rod (609).

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