Inorganic mass spectrum pretreatment equipment

Abstract

The utility model relates to the field of inorganic mass spectrum pretreatment equipment, and discloses inorganic mass spectrum pretreatment equipment which comprises a frame assembly (1), a pipetting module (2), a diluent filling module (3), a first guide driving assembly (4), a sample injection module (5) and a second guide driving assembly (6), the sampling module (5) comprises a sampling needle mounting seat (51) and a sampling needle (52) mounted on the sampling needle mounting seat (51), the sampling needle (52) is used for extracting a sample in a deep hole plate (103) on the deep hole plate mounting module (15), the second guide driving assembly (6) is mounted on the working platform (11), and the second guide driving assembly (6) is used for driving the sampling needle mounting seat (51) to move in the first direction (A), the second direction (B) and the third direction (C). The inorganic mass spectrum pretreatment equipment disclosed by the utility model has higher efficiency.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of medical apparatus and instruments, in particular to the field of inorganic mass spectrum pretreatment equipment. BACKGROUND

[0002] Inorganic mass spectrum is a kind of inorganic multi-element analysis technology for detection by mass spectrum with inductively coupled plasma as ion source.In use, the sample to be analyzed is usually introduced into argon stream in the form of aerosol of aqueous solution, and then enters the inorganic mass spectrometer body for analysis and detection.The sample to be analyzed is generally placed in a reagent tube, but before detection, the sample to be analyzed needs to be pretreated (for example, shaking, mixing, etc.), and then the sample to be analyzed is introduced into the inorganic mass spectrometer for detection.In order to realize efficient detection of a large number of samples to be analyzed and reduce human operation errors and improve test result accuracy, a sampler is needed to automatically sample the sample to be analyzed and transport it into the inorganic mass spectrometer body.The inorganic mass spectrum pretreatment equipment is a sampler to meet such requirements.The full-automatic sample pretreatment device in Chinese patent application with publication No.CN115326912A is a typical inorganic mass spectrum pretreatment equipment in the prior art, which integrates the sampling head movement mechanism 92, the blowing pipe movement mechanism 93 and the sampling needle movement mechanism 94 to form an automatic sampling mechanism 9, so that in the pretreatment process, the sampling needle movement mechanism 94 needs to inject the auxiliary reagent (for example, diluent) in the containing tank 15 into the liquid storage tank on the push-pull mechanism 2 through the sampling needle 943, and then clean the sampling needle 943 on the sampling needle movement mechanism 94, then the sampling head movement mechanism 92 needs to inject the sample to be analyzed in the sampling tube 45 into the corresponding receiving groove on the deep well plate 20b, and then the sampling head movement mechanism 92 needs to inject the auxiliary reagent in the liquid storage tank into the corresponding receiving groove on the deep well plate 20b after replacing the sampling head, and use the blowing pipe movement mechanism 93 to mix the auxiliary reagent with the sample to be analyzed, and finally the sample to be analyzed in the corresponding receiving groove on the deep well plate 20b is extracted by the sampling needle 943 and sent into the mass spectrometer for detection.It can be seen that the sampling head movement mechanism 92 and the sampling needle movement mechanism 94 each need to perform more procedures and consume more time, and the sampling head movement mechanism 92 and the sampling needle movement mechanism 94 are integrated in the sampling mechanism 9, so that the efficiency of the sampling head movement mechanism 92 and the sampling needle movement mechanism 94 is restricted, and ultimately the efficiency of inorganic mass spectrum pretreatment cannot be further improved.

[0003] Therefore, there is a need in the art for an inorganic mass spectrum pretreatment equipment with higher efficiency. SUMMARY

[0004] The utility model aims at providing an inorganic mass spectrum pretreatment equipment with higher efficiency.

[0005] In order to achieve the above object, the utility model provides an inorganic mass spectrum pretreatment equipment, the inorganic mass spectrum pretreatment equipment includes: frame assembly, the inside of frame assembly is provided with work platform, sample tube frame installation module, sample adding needle box installation module, reagent tube installation module for installing calibration reagent tube and / or quality control reagent tube, deep hole plate installation module, waste needle receiving structure, the washing module for washing sample needle and the clamping oscillation module for clamping the body of sample tube and oscillating sample tube are provided on work platform, pipette module, the pipette module is used to take liquid by installing sample adding needle, diluent injection module, the diluent injection module includes injection needle mounting seat and installs diluent injection needle of injection needle mounting seat, and the diluent injection needle is used to inject diluent to the deep hole plate on the deep hole plate installation module, first guide drive assembly, the first guide drive assembly is installed to frame assembly, and the first guide drive assembly is used to drive pipette module and injection needle mounting seat move along the first direction, second direction and third direction perpendicular to each other, sample inlet module, the sample inlet module includes sample needle mounting seat and installs sample needle of sample needle mounting seat, and the sample needle is used to extract the sample in the deep hole plate on the deep hole plate installation module, and second guide drive assembly, the second guide drive assembly is installed to work platform, and the second guide drive assembly is used to drive sample needle mounting seat move along the first direction, the second direction and the third direction.

[0006] Specifically, the deep hole plate installation module includes: a bottom plate installed on the work platform, a sliding installation assembly installed on the bottom plate, a sliding plate slidably installed on the sliding installation assembly between a working position and a sliding-out position, and a deep hole plate base installed on the sliding plate for detachably installing a deep hole plate.

[0007] Specifically, the inorganic mass spectrum pretreatment equipment further includes a lifting installation assembly for lifting the installation position, and the second guide drive assembly is installed on the bottom plate through the lifting installation assembly.

[0008] Specifically, the lifting installation assembly includes a first support plate, a second support plate, and a mounting plate, the first support plate and the second support plate are installed on the bottom plate at a predetermined distance from each other, both ends of the mounting plate are respectively installed on the top of the first support plate and the second support plate, and the second guide drive assembly is installed on the mounting plate.

[0009] Specifically, the lifting installation assembly further includes a first side sealing plate and a second side sealing plate respectively installed on the first support plate, the second support plate, and the mounting plate.

[0010] Specifically, the inorganic mass spectrometry pre-treatment device further comprises an opening and closing cover module for clamping and rotating a tube cover of a sample tube, and a third guide driving assembly installed on the frame assembly and used for driving the opening and closing cover module to move in the first direction, the second direction and the third direction.

[0011] The inorganic mass spectrometry pre-treatment device can maximize the efficiency of the sample injection module and the pipetting module, thereby improving the efficiency of the inorganic mass spectrometry pre-treatment device.

[0012] Other features and advantages of the present application will be described in detail in the following specific embodiments. BRIEF DESCRIPTION OF DRAWINGS

[0013] The accompanying drawings are included to provide a further understanding of the present application, and constitute a part of the specification, and are used to explain the present application together with the following specific embodiments, but do not constitute a limitation on the present application. In the drawings:

[0014] Figure 1 is a perspective view of the specific embodiment of the inorganic mass spectrometry pre-treatment device according to the present application;

[0015] Figure 2 is Figure 1 is an exploded view of the inorganic mass spectrometry pre-treatment device in

[0016] Figure 3 is Figure 1 is an exploded view of the sample injection module, the lifting installation assembly and the deep hole plate installation module in the inorganic mass spectrometry pre-treatment device in

[0017] BRIEF DESCRIPTION OF DRAWINGS

[0018] 1, frame assembly 2, pipetting module

[0019] 3, dilution liquid filling module 4, first guide driving assembly

[0020] 5, sample injection module 6, second guide driving assembly

[0021] 7, lifting installation assembly 8, opening and closing cover module

[0022] 9, third guide driving assembly

[0023] 11, workbench 12, sample tube rack installation module

[0024] 13, sample needle cartridge mounting module 14, reagent tube mounting module

[0025] 15, deep well plate mounting module 16, used needle receiving structure

[0026] 17, cleaning module 18, clamping oscillation module

[0027] 31, filling needle mounting seat 32, diluent filling needle

[0028] 51, sample needle mounting seat 52, sample needle

[0029] 71, first support plate 72, second support plate

[0030] 73, mounting plate 74, first side sealing plate

[0031] 75, second side sealing plate

[0032] 101, sample tube 102, sample needle

[0033] 103, deep well plate

[0034] 151, bottom plate 152, sliding mounting assembly

[0035] 153, sliding plate 154, deep well plate base

[0036] A, first direction B, second direction C, third direction DETAILED DESCRIPTION

[0037] In order to make the purpose, technical scheme and advantages of the embodiments of the present application more clear, the technical scheme in the embodiments of the present application will be described clearly and completely in conjunction with the drawings in the embodiments of the present application. It should be understood that the specific embodiments described here are only used to illustrate and explain the embodiments of the present application, and are not used to limit the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0038] The utility model provides a kind of inorganic mass spectrum pretreatment equipment, specifically, as Figures 1 to 3As shown, the inorganic mass spectrum pretreatment equipment comprises a frame assembly 1, an inner portion of the frame assembly 1 is provided with a workbench 11, the workbench 11 is provided with a sample tube rack installation module 12 (the sample tube 101 containing samples can be detachably installed on the sample tube rack first, and then the sample tube rack is detachably installed on the sample tube rack installation module 12, so that the sample tube 102 is in the installed state), a sample needle box installation module 13, a reagent tube installation module 14 for installing calibration reagent tubes and / or quality control reagent tubes, a deep well plate installation module 15, a waste needle receiving structure 16, a cleaning module 17 for cleaning the sample injection needle 52 and a clamping and oscillation module 18 for clamping the body of the sample tube 101 and oscillating the sample tube 101; a pipetting module 2 for pipetting liquid by installing a sample injection needle 102; a diluent injection module 3 comprising a diluent injection needle 32 installed on a diluent injection needle mounting seat 31, the diluent injection needle 32 being used for injecting diluent into the deep well plate 103 on the deep well plate installation module 15; a first guide driving assembly 4 installed on the frame assembly 1, the first guide driving assembly 4 being used for driving the pipetting module 2 and the diluent injection needle mounting seat 31 to move along a first direction A, a second direction B and a third direction C perpendicular to each other; a sample injection module 5 comprising a sample injection needle 52 installed on a sample injection needle mounting seat 51, the sample injection needle 52 being used for extracting samples in the deep well plate 103 on the deep well plate installation module 15; and a second guide driving assembly 6 installed on the workbench 11, the second guide driving assembly 6 being used for driving the sample injection needle mounting seat 51 to move along the first direction A, the second direction B and the third direction C.

[0039] The inorganic mass spectrum pretreatment equipment of the utility model can maximize the efficiency of the sample injection module 5 and the pipetting module 2 by distributing the diluent injection and sample extraction to the diluent injection module 3 and the sample injection module 5, and driving the sample injection module 5 by a separate second guide driving assembly 6, thereby improving the efficiency of the inorganic mass spectrum pretreatment equipment.

[0040] It should be noted that the specific structural form or specific type of the frame assembly 1, the pipetting module 2, the diluent injection module 3, the first guide driving assembly 4, the sample injection module 5, the second guide driving assembly 6, the sample tube rack installation module 12, the sample needle box installation module 13, the reagent tube installation module 14, the deep well plate installation module 15, the waste needle receiving structure 16, the cleaning module 17 and the clamping and oscillation module 18 can be set as required, which belongs to the technical concept range of the utility model.

[0041] In the inorganic mass spectrum pretreatment equipment, specifically, as shown in Figure 3 The deep hole plate mounting module 15 includes a bottom plate 151 mounted on the work platform 11, a sliding mounting assembly 152 mounted on the bottom plate 151, a sliding plate 153 slidably mounted on the sliding mounting assembly 152 between a working position and a sliding-out position, and a deep hole plate base 154 mounted on the sliding plate 153 and used for detachably mounting the deep hole plate 103, so that the deep hole plate 103 can be more conveniently mounted on the deep hole plate base 154 and detached from the deep hole plate base 154 by sliding the position of the sliding plate 153.

[0042] In the inorganic mass spectrum pretreatment equipment, more specifically, the inorganic mass spectrum pretreatment equipment further includes a lifting mounting assembly 7 for lifting the mounting position, and the second guide driving assembly 6 is mounted on the bottom plate 151 through the lifting mounting assembly 7, so that the second guide driving assembly 6 can be mounted to a predetermined position (a position slightly higher than the deep hole plate on the deep hole plate base 154) by the lifting mounting assembly 7, and the sample feeding module 5 is located above the deep hole plate on the deep hole plate base 154.

[0043] In the inorganic mass spectrum pretreatment equipment, further specifically, the lifting mounting assembly 7 includes a first support plate 71, a second support plate 72 and a mounting plate 73, the first support plate 71 and the second support plate 72 are mounted on the bottom plate 151 at a predetermined distance from each other, and the two ends of the mounting plate 73 are respectively mounted on the top of the first support plate 71 and the second support plate 72, and the second guide driving assembly 6 is mounted on the mounting plate 73.

[0044] In the inorganic mass spectrum pretreatment equipment, further specifically, the lifting mounting assembly 7 further includes a first side sealing plate 74 and a second side sealing plate 75 mounted on the first support plate 71, the second support plate 72 and the mounting plate 73, respectively.

[0045] In the inorganic mass spectrum pretreatment equipment, specifically, as shown in Figure 1 and Figure 2As shown, the inorganic mass spectrometry pretreatment device further comprises an opening and closing cover module 8 for clamping and rotating the tube cover of the sample tube 101, and a third guide driving assembly 9 installed on the frame assembly 1, which is used to drive the opening and closing cover module 8 to move along the first direction A, the second direction B and the third direction C, so that the tube cover of the sample tube 101 can be clamped by the opening and closing cover module 8 and the tube body of the sample tube 101 can be clamped by the clamping oscillation module 18, and then the opening and closing cover of the sample tube 101 can be realized by driving the opening and closing cover module 8 to rotate the tube cover of the sample tube 101.

[0046] The preferred embodiments of the present application are described in detail above in combination with the drawings, but the present application is not limited to the specific details in the above-described embodiments. Within the technical concept range of the present application, various simple modifications can be made to the technical solutions of the present application, and these simple modifications all belong to the protection range of the present application.

[0047] In addition, it should be noted that each specific technical feature described in the above specific embodiments can be combined in any appropriate manner without contradiction. In order to avoid unnecessary repetition, various possible combinations are not described again in the present application.

[0048] In addition, various different embodiments of the present application can also be combined in any manner, as long as it does not deviate from the idea of the present application, and it should be considered as disclosed in the present application.

Claims

1. An inorganic mass spectrometry pre-treatment apparatus, characterized by, The inorganic mass spectrometry pre-treatment device comprises: a frame assembly (1), an inner part of the frame assembly (1) is provided with a working platform (11), the working platform (11) is provided with a sample tube rack mounting module (12), a sample adding needle box mounting module (13), a reagent tube mounting module (14) for mounting a calibration reagent tube and / or a quality control reagent tube, a deep well plate mounting module (15), a waste needle receiving structure (16), a cleaning module (17) for cleaning a sample injection needle (52), and a clamping and oscillation module (18) for clamping a body of a sample tube (101) and oscillating the sample tube (101); a pipetting module (2) for pipetting liquid by mounting a sample adding needle (102); a diluent filling module (3) comprising a filling needle mounting seat (31) and a diluent filling needle (32) mounted on the filling needle mounting seat (31), the diluent filling needle (32) being used for filling diluent to a deep well plate (103) on the deep well plate mounting module (15); a first guide driving assembly (4) mounted on the frame assembly (1), the first guide driving assembly (4) being used for driving the pipetting module (2) and the filling needle mounting seat (31) to move along a first direction (A), a second direction (B) and a third direction (C) perpendicular to each other; a sample injection module (5) comprising a sample injection needle mounting seat (51) and a sample injection needle (52) mounted on the sample injection needle mounting seat (51), the sample injection needle (52) being used for extracting a sample in the deep well plate (103) on the deep well plate mounting module (15); and a second guide driving assembly (6) mounted on the working platform (11), the second guide driving assembly (6) being used for driving the sample injection needle mounting seat (51) to move along the first direction (A), the second direction (B) and the third direction (C).

2. The inorganic mass spectrometry pre-treatment device according to claim 1, characterized in that, The deep well plate mounting module (15) comprises a bottom plate (151) mounted on the working platform (11), a sliding mounting assembly (152) mounted on the bottom plate (151), a sliding plate (153) slidably mounted on the sliding mounting assembly (152) between a working position and a sliding-out position, and a deep well plate base (154) mounted on the sliding plate (153), the deep well plate base (154) being used for detachably mounting a deep well plate (103).

3. The inorganic mass spectrometry pre-treatment device according to claim 2, characterized in that, The inorganic mass spectrometry pre-treatment device further comprises a lifting mounting assembly (7) for lifting a mounting position, and the second guide driving assembly (6) is mounted on the bottom plate (151) through the lifting mounting assembly (7).

4. The inorganic mass spectrometry pre-treatment device according to claim 3, characterized in that The lifting mounting assembly (7) comprises a first support plate (71), a second support plate (72) and a mounting plate (73), the first support plate (71) and the second support plate (72) are installed on the bottom plate (151) at a predetermined distance from each other, two ends of the mounting plate (73) are respectively installed on the top of the first support plate (71) and the second support plate (72), and the second guide driving assembly (6) is installed on the mounting plate (73).

5. The inorganic mass spectrometry pre-treatment device according to claim 4, characterized in that The lifting mounting assembly (7) further comprises a first side sealing plate (74) and a second side sealing plate (75) respectively installed on the first support plate (71), the second support plate (72) and the mounting plate (73).

6. The inorganic mass spectrometry pre-treatment device according to any one of claims 1 to 5, characterized in that The inorganic mass spectrometry pretreatment device further comprises: An opening and closing cover module (8) for clamping and rotating the cover of the sample tube (101); and A third guide driving assembly (9) installed on the frame assembly (1), the third guide driving assembly (9) is used for driving the opening and closing cover module (8) to move along the first direction (A), the second direction (B) and the third direction (C).

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