Stirring device suitable for immunoaffinity filler coupling

Abstract

The utility model relates to the technical field of biological separation and purification, in particular to a stirring device suitable for immunoaffinity filler coupling, which comprises a base, a bottle body and a filter part. A liquid inlet opening is formed in one end face of the base, a liquid cavity communicated with the liquid inlet opening is formed in the base, and a liquid outlet communicated with the liquid cavity is further formed in the base; the bottle body is provided with a stirring cavity, a communicating opening and a stirring opening are formed in the two ends of the bottle body respectively, and the bottle body is arranged on the base. Through the arrangement of the filter part, the stirring device can realize solid-liquid separation only by opening the liquid outlet after stirring is completed. The filler particles are effectively blocked in the stirring chamber by the filter part, and the liquid enters the liquid chamber through the filter part and is finally discharged from the liquid outlet. By means of the design, the tedious steps of manual solid-liquid separation are omitted, for example, liquid is sucked out through a pipette or supernatant is discarded through centrifugation, and the operation efficiency and convenience are remarkably improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of biological separation and purification, in particular to a stirring device suitable for immunoaffinity filler coupling. BACKGROUND

[0002] The traditional self-made immunoaffinity chromatography filler coupling process mainly washes the filler through stirring and centrifugation. Although this process is relatively simple to operate, it has many shortcomings. It relies on centrifugation to make the filler settle, and then the operator needs to manually pour or suck out the buffer supernatant from the centrifuge tube with a pipette, and then re-add liquid and place it in a water bath shaker for oscillation and mixing. This series of steps needs to be repeated multiple times, which not only leads to low work efficiency and increases the workload of the operator, but also increases the risk of damage to the structure of the filler microspheres in the process of reducing the workload of repeated centrifugation. CONTENT OF THE UTILITY MODEL

[0003] The purpose of the present application is to provide a stirring device suitable for immunoaffinity filler coupling, which can save operation steps, improve efficiency and reduce the burden of the operator.

[0004] In order to achieve the above-mentioned purpose, the embodiment of the present application provides a stirring device suitable for immunoaffinity filler coupling, which comprises a base, a bottle body and a filter. One end face of the base is provided with a liquid inlet opening, and the base has a liquid chamber communicating with the liquid inlet opening, and the base is also provided with a liquid outlet port communicating with the liquid chamber; the bottle body has a stirring chamber, and the two ends of the bottle body are respectively provided with a communication port and a stirring port, the bottle body is arranged on the base, the communication port communicates with the liquid inlet opening, and the liquid in the stirring chamber can enter the base from the communication port and the liquid inlet opening and be discharged through the liquid outlet port on the base; the filter is arranged between the liquid inlet opening and the communication port, and the filter is used to filter the liquid flowing from the bottle body to the base.

[0005] In one embodiment, the stirring device further comprises a bottle cap and a stirring member, the bottle cap is arranged at the stirring port of the bottle body; the stirring member comprises a stirring rod and a stirring blade, one end of the stirring rod is rotatably installed on the bottle cap, and the stirring blade is installed on the other end of the stirring rod, and the stirring blade is located in the stirring chamber.

[0006] In one embodiment, the stirring blade has a rotation radius L around the stirring rod, and the inner wall radius of the bottle body is R, wherein 0.8R≤L<R.

[0007] In one embodiment, the stirring device further comprises a motor, the motor is arranged in the bottle cap, an output shaft of the motor is in transmission connection with the stirring rod, and the motor rotates to drive the stirring rod to rotate.

[0008] In one embodiment, the stirring device further comprises a first controller and an interactive element, the first controller is electrically connected with the motor, and the first controller controls an operating parameter of the motor; and the interactive element is electrically connected with the first controller, and the interactive element converts a user operation action into an executable command and transmits the executable command to the first controller.

[0009] In one embodiment, the stirring device further comprises a sealing gasket, the sealing gasket is arranged on one side of the filter element close to the liquid inlet opening and / or on one side of the filter element close to the communication opening, so as to seal the filter element with the liquid inlet opening of the base and / or the communication opening of the bottle body.

[0010] In one embodiment, the stirring device further comprises a second controller and a display, the display is electrically connected with the second controller.

[0011] In one embodiment, the stirring device further comprises a pH value detector, the pH value detector is arranged in the liquid chamber for detecting a pH value of the liquid, the pH value detector is electrically connected with the second controller, the pH value detector sends a detection result to the second controller, and the second controller displays the pH value detection result through the display.

[0012] In one embodiment, the stirring device further comprises a temperature detector, the temperature detector is arranged in the liquid chamber for detecting a temperature of the liquid, the temperature detector is electrically connected with the second controller, the temperature detector sends a detection result to the second controller, and the second controller displays the temperature detection result through the display.

[0013] In one embodiment, the stirring device further comprises a liquid discharge pipe, the liquid discharge pipe is connected with the liquid discharge opening, and a valve body is arranged on the liquid discharge pipe, the valve body can open or close the liquid discharge pipe.

[0014] In the above technical solution, by arranging the filter element, the stirring device can realize solid-liquid separation only by opening the liquid discharge opening after stirring is completed. The solid particles are effectively blocked in the stirring chamber by the filter element, and the liquid passes through the filter element to enter the liquid chamber and is finally discharged from the liquid discharge opening. This design eliminates the cumbersome steps of manually separating solid and liquid, such as using a pipette to suck out the liquid or pouring out the liquid, and significantly improves the operation efficiency and convenience.

[0015] Other features and advantages of the present application will be illustrated in the following detailed description of embodiments. BRIEF DESCRIPTION OF DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments. It should be understood that the following drawings only show some of the embodiments of the present application, and therefore should not be considered as a limitation to the scope. For those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0017] Figure 1 A perspective view of the structure of one of the embodiments of the stirring device suitable for coupling of the immunoaffinity filler provided by the present application;

[0018] Figure 2 An exploded view of one of the embodiments of the stirring device suitable for coupling of the immunoaffinity filler provided by the present application;

[0019] Figure 3 A perspective view of the structure of one of the embodiments of the bottle cap of the stirring device suitable for coupling of the immunoaffinity filler provided by the present application;

[0020] Figure 4 A perspective view of the structure of another embodiment of the bottle cap of the stirring device suitable for coupling of the immunoaffinity filler provided by the present application.

[0021] FIG.:

[0022] 100 - bottle cap;

[0023] 200 - bottle body; 210 - stirring chamber; 220 - communication port; 230 - stirring port;

[0024] 300 - base; 310 - liquid discharge pipe; 330 - liquid inlet opening; 340 - liquid chamber;

[0025] 400 - stirring member; 410 - motor; 420 - stirring rod; 430 - stirring blade;

[0026] 510 - filter member; 520 - sealing gasket; 550 - interaction member; 560 - display; 570 - power switch; 580 - charging interface. DETAILED DESCRIPTION

[0027] In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are some embodiments but not all of the embodiments of the present application. The components of the embodiments of the present application described and shown in the drawings can be arranged and designed in various different configurations.

[0028] In the description of the present application, it should be noted that the positions or location relationships indicated by the terms "inner", "outer" and the like are based on the positions or location relationships shown in the drawings or the positions or location relationships in which the products of the present application are usually placed, which are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the indicated devices or elements must have a particular position, be constructed and operated in a particular position, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first", "second" and the like are only used for differentiation in description and cannot be understood as indicating or implying relative importance.

[0029] In the description of the present application, it should be noted that, unless otherwise explicitly specified and limited, the terms "set", "connected" should be understood broadly, for example, can be fixedly connected, can be detachably connected, or integrally connected; can be directly connected, or indirectly connected through an intermediate medium, can be the communication inside two elements. For those skilled in the art, the specific meanings of the above terms in the present application can be understood according to the specific circumstances.

[0030] The embodiments of the present application provide a stirring device suitable for immunoaffinity filler coupling, as shown in Figure 1 and Figure 2 The stirring device comprises a base 300, a bottle body 200 and a filter piece 510.

[0031] As shown in Figure 2 , one end surface of the base 300 is provided with a liquid inlet opening 330, and the base 300 has a liquid chamber 340 communicating with the liquid inlet opening 330, and the base 300 is further provided with a liquid outlet port communicating with the liquid chamber 340.

[0032] The liquid enters the liquid chamber 340 of the base 300 through the liquid inlet opening 330, and the liquid in the liquid chamber 340 is discharged through the liquid outlet port.

[0033] The bottle body 200 has a stirring chamber 210, and the two ends of the bottle body 200 are respectively provided with a communicating port 220 and a stirring port 230, and the bottle body 200 is arranged on the base 300. Exemplarily, the base 300 and the bottle body 200 are connected through threads, and in another embodiment, the base 300 and the bottle body 200 are connected through clamping.

[0034] The communication port 220 is in communication with the liquid inlet opening 330, and the liquid in the stirring chamber 210 can flow into the base 300 from the communication port 220 and the liquid inlet opening 330, and be discharged through the liquid outlet on the base 300.

[0035] The filter 510 is arranged between the liquid inlet opening 330 and the communication port 220, and the filter 510 is used to filter the liquid flowing from the bottle body 200 to the base 300. The filter 510 is detachably arranged between the liquid inlet opening 330 and the communication port 220, but in another embodiment, the filter 510 is fixedly arranged at the liquid inlet opening 330 of the base 300; in yet another embodiment, the filter 510 is fixedly arranged at the communication port 220 of the bottle body 200.

[0036] In use, the material (the material is a liquid with solid particles) first enters the stirring chamber 210 from the stirring port 230, and then enters the liquid chamber 340 of the base 300 through the communication port 220 and the liquid inlet opening 330. After the liquid chamber 340 is filled with the material, part of the material is still in the stirring chamber 210, and during the flow of the material from the stirring chamber 210 to the liquid chamber 340, the filter 510 blocks the solid particles in the material from entering the liquid chamber 340. The liquid in the stirring chamber 210 is stirred. The material in the stirring chamber 210 is stirred, and at the same time, the material in the liquid chamber 340 is also stirred. After stirring is completed, the liquid outlet is opened, and the liquid in the liquid chamber 340 and the stirring chamber 210 is discharged from the liquid outlet.

[0037] Through the arrangement of the filter 510, the stirring device can realize solid-liquid separation only by opening the liquid outlet after stirring is completed. The solid particles are effectively blocked in the stirring chamber 210 by the filter 510, while the liquid passes through the filter 510 into the liquid chamber 340 and is finally discharged from the liquid outlet. This design eliminates the cumbersome steps of manually separating solid and liquid, such as using a pipette to suck out the liquid or pouring the liquid, and significantly improves the operation efficiency and convenience.

[0038] The arrangement of the filter 510 can effectively filter out the solid particles in the material and prevent them from entering the liquid chamber 340, thereby ensuring the smooth progress of subsequent processing.

[0039] The stirring device is particularly suitable for experimental or production links of immunoaffinity filler coupling process. At the same time, its efficient solid-liquid separation capability and optimized stirring effect also make the device have a wide application prospect in the fields of scientific research, biopharmaceuticals, chemical industry, etc.

[0040] As shown in Figure 1 and Figure 2 , in one embodiment, the stirring device further comprises a bottle cap 100 and a stirring member 400.

[0041] The cap 100 is disposed at the stirring port 230 of the bottle body 200; exemplarily, the cap 100 is threaded or snap-fitted at the stirring port 230 of the bottle body 200.

[0042] The stirring component 400 includes a stirring rod 420 and a stirring blade 430. One end of the stirring rod 420 is rotatably mounted on the bottle cap 100, and the stirring blade 430 is mounted on the other end of the stirring rod 420. The stirring blade 430 is located in the stirring chamber 210. The rotation of the stirring rod 420 drives the stirring blade 430 to rotate, and the rotation of the stirring blade 430 stirs the material in the stirring chamber 210.

[0043] The design of the mixing element 400, especially the combination of the mixing rod 420 and the mixing blades 430, makes the mixing process more efficient. The mixing blades 430 are located directly in the mixing chamber 210. As the mixing rod 420 rotates, the mixing blades 430 can fully mix the materials, ensuring that the materials are uniformly mixed within the mixing chamber 210. This design helps to improve mixing efficiency.

[0044] The design of the cap 100, particularly its threaded or snap-fit ​​connection at the stirring port 230 of the bottle body 200, enhances the sealing performance of the mixing device. This sealing design helps prevent material leakage during mixing, thus ensuring the continuity and stability of the mixing process. Simultaneously, it avoids material contamination of the external environment, meeting the cleanliness requirements of laboratory or production environments.

[0045] The design of the cap 100 and the agitator 400 simplifies the operation and maintenance of the mixing device. The cap 100 can be easily opened and closed, facilitating the addition of materials to the mixing chamber 210 or the removal of mixed materials. This design improves the ease of use and durability of the mixing device.

[0046] For example, the bottle body 200 is made of a transparent material, such as polycarbonate or glass. For example, the cap 100, the stirring blade 430, and the base 300 are made of an opaque material, such as polyethylene.

[0047] like Figure 1 As shown, in one embodiment, the radius of rotation of the stirring blade 430 around the stirring rod 420 is L, and the radius of the inner wall of the bottle body 200 is R, wherein 0.8R≤L<R.

[0048] For example, L = 0.8R. In another embodiment, L = 0.85R. In another embodiment, L = 0.9R. In yet another embodiment, L = 0.95R.

[0049] 0.8R≤L<R, so that the stirring blade 430 can reach more than 80% coverage area when stirring, ensuring the stirring sufficiency. In the stirring process, the larger the coverage area of the stirring blade 430, the higher the stirring efficiency. By optimizing the rotation radius L of the stirring blade 430, the stirring efficiency can be improved without increasing the stirring power, so that the reaction is more rapid and thorough.

[0050] If L<0.8R, the stirring effect of the stirring blade 430 is insufficient.

[0051] If L≥R, the stirring blade 430 will interfere with the inner wall of the bottle body 200, which not only aggravates the wear of the bottle body 200 and the stirring blade 430, but also affects the stirring effect, and even causes damage to the stirring device. By setting a reasonable rotation radius ratio, this situation can be avoided, prolonging the service life of the stirring device. Since the interference between the stirring blade 430 and the inner wall of the bottle body 200 is effectively avoided, equipment failure and downtime caused by wear can be reduced. This helps to reduce operating and maintenance costs and improve the overall economic benefits of the stirring device.

[0052] As shown in Figure 1 and Figure 2 In one embodiment, the stirring part 400 further comprises a motor 410, the motor 410 is arranged in the bottle cap 100, the output shaft of the motor 410 is in transmission connection with the stirring rod 420, and the motor 410 rotates to drive the stirring rod 420 to rotate.

[0053] Exemplarily, the motor 410 is a 25W brushless motor, suitable for 220V, 50HZ power supply, and equipped with a 66W AC-DC power adapter.

[0054] However, in another embodiment, the motor 410 includes but is not limited to: a direct current motor 410, an alternating current motor 410, a stepping motor 410, a servo motor 410 or a switched reluctance motor 410, etc.

[0055] Exemplarily, the motor 410 has a rotation speed of 200-400 rpm, and of course other rotation speeds are also available.

[0056] The arrangement of the motor 410 enables the stirring rod 420 to rotate, thereby driving the stirring blade 430 to stir. The driving force of the motor 410 can ensure that the stirring process is carried out efficiently, so that the substances in the bottle are fully mixed, improving the stirring effect.

[0057] By arranging the motor 410 in the bottle cap 100, the space at the top of the container can be fully utilized, avoiding the additional occupation of external space. This compact structure design not only facilitates carrying and transportation, but also reduces production costs and land area.

[0058] As shown in Figure 2and Figure 3 As shown, in one embodiment, the stirring component 400 further includes a first controller and an interaction component 550.

[0059] The first controller is electrically connected to the motor 410. The first controller controls the operating parameters of the motor 410, including but not limited to: speed, direction of rotation, running time, and timed start time.

[0060] The interactive element 550 is electrically connected to the first controller. The interactive element 550 converts user operations into executable commands and transmits them to the first controller. The user transmits executable commands to the first controller through the interactive element 550 to control the operating parameters of the motor 410.

[0061] For example, the interactive element 550 includes, but is not limited to: a button adjustment unit, a knob adjustment unit, a touch screen adjustment unit, and combinations thereof.

[0062] Exemplarily, the first controller includes, but is not limited to, a central processing unit (CPU), a programmable logic controller (PLC), or an electronic device with logic control functions. Exemplarily, the first controller is disposed on the bottle cap 100.

[0063] like Figure 3 As shown, in another embodiment, a power switch 570 is provided on the bottle cap 100, which is electrically connected to the motor 410 to control the start and stop of the motor 410.

[0064] Through the settings of the interactive component 550, users can intuitively control the operating parameters of the motor 410, such as speed, direction, running time, and timed start time. This design makes operation simpler and more intuitive, improving the user experience.

[0065] like Figure 4 As shown, in one embodiment, a charging interface 580 is provided on the bottle cap 100, and the motor 410 is electrically connected to the charging interface 580. The motor 410 receives external electrical energy through the charging interface 580.

[0066] like Figure 2 As shown, in one embodiment, the stirring device further includes a sealing gasket 520, which is disposed on the side of the filter element 510 near the liquid inlet 330 and / or on the side of the filter element 510 near the communication port 220, so that the filter element 510 is in a sealing fit with the liquid inlet 330 of the base 300 and / or the communication port 220 of the bottle body 200.

[0067] For example, a sealing gasket 520 is disposed on the side of the filter element 510 near the liquid inlet opening 330 to provide a sealing fit between the filter element 510 and the liquid inlet opening 330 of the base 300. In another embodiment, the sealing gasket 520 is disposed on the side of the filter element 510 near the communication port 220 to provide a sealing fit between the filter element 510 and the communication port 220 of the bottle body 200. Figure 2 As shown, in another embodiment, two sealing gaskets 520 are provided. One sealing gasket 520 is provided on the side of the filter element 510 near the liquid inlet opening 330, and the other sealing gasket 520 is provided on the side of the filter element 510 near the connecting port 220. The two sealing gaskets 520 make the filter element 510 seal against the base 300 and the bottle body 200.

[0068] like Figure 2 As shown, in one embodiment, the stirring device further includes a second controller and a display 560.

[0069] The display 560 is electrically connected to a second controller, which controls the display 560 to display information. Exemplarily, the display 560 is mounted on the base 300. In some embodiments, the display 560 is mounted on the bottle body 200, and in another embodiment, the display 560 is mounted on the bottle cap 100.

[0070] For example, the display 560 includes, but is not limited to: CRT display (Cathode Ray Tube), LCD display (Liquid Crystal Display), LED display, OLED display (Organic Light-Emitting Diode), QLED display (Quantum Dot Light-Emitting Diode), Mini LED display, Micro LED display and 3D display, etc.

[0071] For example, the second controller includes, but is not limited to, a central processing unit (CPU), a programmable logic controller (PLC), or an electronic device with logic control functions.

[0072] For example, the second controller is set on the base 300. Of course, the second controller can also be set in other locations, such as on the bottle body 200 or the bottle cap 100.

[0073] In one embodiment, the stirring device further includes a pH detector disposed in the liquid chamber 340 for detecting the pH value of the liquid. The pH detector is electrically connected to a second controller, and the pH detector sends the detection result to the second controller, which displays the pH detection result on a display 560. Exemplarily, the pH detector is capable of continuously acquiring the pH value; however, in another embodiment, the pH detector is capable of acquiring the pH value at a desired time.

[0074] In one embodiment, the stirring device further includes a temperature detector, which is disposed in the liquid chamber 340 for detecting the liquid temperature. The temperature detector is electrically connected to a second controller, and the temperature detector sends the detection result to the second controller, which displays the temperature detection result on a display 560.

[0075] For example, the temperature detector is able to continuously acquire temperature parameters, but in another embodiment, the temperature detector is able to acquire temperature parameters at the desired time.

[0076] Users can monitor reaction environment conditions and determine the progress of the operation by setting pH and temperature detectors.

[0077] In the preparation of immunoaffinity packing materials, the pH and temperature of the buffer environment are two critical factors. Therefore, the base 300 is equipped with a pH detector and a temperature detector embedded in its inner wall to monitor the reaction process. During the washing process, all buffer solutions are generally pre-cooled to ensure the reaction occurs at a low temperature. Temperature detection allows the operator to clearly and promptly understand the reaction temperature. pH affects the reaction efficiency between the packing material and the antibody, as well as antibody activity. Furthermore, after the antibody coupling reaction, the packing material undergoes an ethanolamine blocking reaction and alternating washing with acid and alkaline buffer solutions. Therefore, the pH detection function not only helps the operator observe changes in the reaction environment but also helps determine whether a particular washing step has been completed thoroughly.

[0078] For example, the power-consuming components on the base 300 can be powered by a battery or directly connected to a power source. These power-consuming components include, but are not limited to, a temperature detector, a pH detector, a display 560, and a second controller.

[0079] like Figure 1 and Figure 2 As shown, in one embodiment, the stirring device further includes a drain pipe 310 connected to a drain port, and a valve body is provided on the drain pipe 310, which can open or close the drain pipe 310.

[0080] It should be noted that, where there is no conflict, the features in the embodiments of this application can be combined with each other.

[0081] The above descriptions are only the preferred embodiments of the present application, and are not intended to limit the present application. The present application can have various modifications and changes for those skilled in the art. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A stirring device suitable for coupling with immunoaffinity fillers, characterized in that, include: A base (300) is provided with a liquid inlet opening (330) on one end face of the base (300), and a liquid chamber (340) communicating with the liquid inlet opening (330) is provided inside the base (300). A drain outlet communicating with the liquid chamber (340) is also provided on the base (300). The bottle body (200) has a stirring chamber (210), and the bottle body (200) has a connecting port (220) and a stirring port (230) at both ends. The bottle body (200) is mounted on the base (300). The connecting port (220) is connected to the liquid inlet (330). The liquid in the stirring chamber (210) can enter the base (300) from the connecting port (220) and the liquid inlet (330) and be discharged through the drain port on the base (300). A filter element (510) is disposed between the liquid inlet (330) and the connecting port (220) for filtering liquid flowing from the bottle body (200) to the base (300).

2. The stirring device for immunoaffinity packing coupling according to claim 1, characterized in that, Also includes: A bottle cap (100) is disposed at the stirring port (230) of the bottle body (200); A stirring component (400) includes a stirring rod (420) and a stirring blade (430). One end of the stirring rod (420) is rotatably mounted on the bottle cap (100), and the stirring blade (430) is mounted on the other end of the stirring rod (420). The stirring blade (430) is located in the stirring chamber (210).

3. The stirring device for immunoaffinity packing coupling according to claim 2, characterized in that, The radius of rotation of the stirring blade (430) around the stirring rod (420) is L, and the radius of the inner wall of the bottle body (200) is R, wherein 0.8R≤L<R.

4. The stirring device for immunoaffinity packing coupling according to claim 2, characterized in that, The stirring component (400) further includes: A motor (410) is installed inside the bottle cap (100). The output shaft of the motor (410) is connected to the stirring rod (420) for transmission. The rotation of the motor (410) drives the stirring rod (420) to rotate.

5. The stirring device for immunoaffinity packing coupling according to claim 4, characterized in that, The stirring component (400) further includes: A first controller is electrically connected to the motor (410) and controls the operating parameters of the motor (410). An interactive element (550) is electrically connected to the first controller, and the interactive element (550) converts user operation actions into executable commands and transmits them to the first controller.

6. The stirring device for immunoaffinity packing coupling according to claim 1, characterized in that, Also includes: A sealing gasket (520) is disposed on the side of the filter element (510) near the liquid inlet opening (330) and / or on the side of the filter element (510) near the communication port (220) to make the filter element (510) seal with the liquid inlet opening (330) of the base (300) and / or the communication port (220) of the bottle body (200).

7. The stirring device for immunoaffinity packing coupling according to claim 1, characterized in that, Also includes: Second controller; A display (560) is electrically connected to the second controller.

8. The stirring device for immunoaffinity packing coupling according to claim 7, characterized in that, Also includes: A pH detector is installed in the liquid chamber (340) to detect the pH value of the liquid. The pH detector is electrically connected to the second controller and sends the detection result to the second controller. The second controller displays the pH detection result through the display (560).

9. The stirring device for immunoaffinity packing coupling according to claim 7, characterized in that, Also includes: A temperature detector is disposed in the liquid chamber (340) for detecting the liquid temperature. The temperature detector is electrically connected to the second controller and sends the detection result to the second controller. The second controller displays the temperature detection result through the display (560).

10. The stirring device for immunoaffinity packing coupling according to claim 1, characterized in that, Also includes: A drain pipe (310) is connected to the drain port. A valve body is provided on the drain pipe (310), which can open or close the drain pipe (310).

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