Micro-flow reaction device

By introducing multi-layer flow guiding components and spiral slow-flow tubes into the microflow reaction device, the problems of insufficient solution mixing and excessive space occupation are solved, achieving thorough mixing and efficient reaction of the solution.

CN223717100UActive Publication Date: 2025-12-26CHANGZHOU NAYANG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202423289152.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-12-26
Estimated Expiration
2034-12-31

AI Technical Summary

Technical Problem

In existing microflow reaction devices, insufficient mixing of solutions leads to inaccurate detection results, and the devices occupy too much space, have excessively long mixing reaction times, and are inefficient.

Method used

A multi-layer flow guide component was designed inside the mixing cylinder to achieve thorough mixing of the solution through multiple impacts, and a spiral flow-slowing tube was used to increase the contact area and efficiency of the coolant.

Benefits of technology

This method achieves thorough mixing of the solution, improves the accuracy of detection results, reduces the space occupied by the device, shortens the reaction time, and improves the efficiency of the mixing reaction.

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Abstract

The utility model provides a micro-flow reaction device which comprises a reaction box, an input pipe is inserted into the side wall of the reaction box in a penetrating mode, a first flow slowing pipe is detachably connected into the reaction box, one end of the first flow slowing pipe is detachably connected with the input pipe, and the other end of the first flow slowing pipe is detachably connected with a mixing cylinder of a multi-layer design. A second slow flow pipe is inserted into one side of the mixing cylinder, an output pipe is inserted into one end of the second slow flow pipe, the output pipe penetrates through the side wall of the reaction box, and the solution is mixed again through the mixing cylinder, so that the solution is impacted for multiple times in the mixing cylinder, the solution is fully mixed, and the inaccurate detection result caused by insufficient mixing of the solution is avoided; and excessive space occupation caused by increase of the reaction device can be avoided.
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Description

TECHNICAL FIELD

[0001] The utility model relates to chemical detection device technical field especially relates to a micro - flow reaction device. BACKGROUND

[0002] Micro - flow reaction device, also called microfluidic reaction device, refers to the system that handles or manipulates small amount fluid on micro - scale, these systems utilize the channel of size is dozens to hundreds of microns, microfluidic device can simulate complex in - vivo environment, provides a stable, controllable and efficient culture system, can also be used as detection equipment, realizes the rapid low - cost detection to various target molecules, or as manufacturing equipment produces bone graft or bone organ.

[0003] In the patent with the publication number CN221733306U discloses a continuous flow microwave chemical reaction device, including single -mode microwave reaction cavity, continuous flow reactor and cooling system, continuous flow reactor is located in single -mode microwave reaction cavity, cooling system carries out cooling to continuous flow reactor, and continuous flow reactor is arranged in spiral, although the cooling system carries out cooling to continuous flow reactor, avoids the influence that temperature change of solution in continuous flow reactor leads to reaction rate because of reaction heat release, but because continuous flow reactor is arranged in spiral, solution mixes only through flowing along the inner wall of continuous flow reactor when mixing, and the mixing efficiency is poor, still can lead to insufficient mixing, influence the determination of the detection result of solution ultimately, and in order to make mixing, reaction sufficient and prolong continuous flow reactor will make the space occupation of device increase, cause unnecessary space waste, and the mixing time of solution in continuous flow reactor will be prolonged, makes the operation time of whole mixing reaction lengthen, and the efficiency is lower.

[0004] Therefore, it is necessary to provide a new micro - flow reaction device to solve the above technical problems. UTILITY MODEL CONTENT

[0005] To solve the above technical problems, the utility model provides a micro - flow reaction device.

[0006] The micro - flow reaction device provided by the utility model comprises a reaction box, an input pipe is inserted through the side wall of the reaction box, a first slow flow pipe is detachably connected in the reaction box, one end of the first slow flow pipe is detachably connected with the input pipe, and the other end of the first slow flow pipe is detachably connected with a mixed cylinder designed in multiple layers, a second slow flow pipe is inserted through one side of the mixed cylinder, one end of the second slow flow pipe is inserted with an output pipe, and the output pipe passes through the side wall of the reaction box.

[0007] Preferably, the output pipe is provided with a plurality of conduits, the other ends of the conduits are inserted into the pumping member, one end of the output pipe is detachably connected with a detection assembly, one side of the detection assembly is provided with a drain port, and one side of the detection assembly is detachably connected with a waste liquid tank.

[0008] Preferably, the mixing cylinder is provided with a fixed column, a plurality of drainage assemblies are fixedly connected to the side wall of the fixed column, and the other ends of the plurality of drainage assemblies are fixedly connected to the inner side wall of the mixing cylinder.

[0009] Preferably, the drainage assembly comprises a first drainage block and a second drainage block, the first drainage block is in the shape of a circular truncated cone, the first drainage block is fixedly connected to the side wall of the fixed column, and the second drainage block is in the shape of a circular column with a circular truncated cone-shaped through hole.

[0010] Preferably, the side wall of the reaction box is provided with an injection port and a flow port, the flow port is located above the injection port, and the injection port and the flow port are both provided with a water stop valve.

[0011] Preferably, the first slow-flow pipe and the second slow-flow pipe are both in the shape of a spiral.

[0012] Preferably, the pumping member comprises a peristaltic pump.

[0013] Preferably, the conduits are all provided with one-way valves.

[0014] Compared with the related art, the micro-flow reaction device has the following beneficial effects:

[0015] The micro-flow reaction device can avoid the problem of inaccurate detection results caused by insufficient mixing of the solution, and can also avoid the problem of excessive space occupation caused by the growth of the reaction device. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 The micro-flow reaction device provided by the utility model is shown in the whole structure diagram Figure 1

[0017] Figure 2 The micro-flow reaction device provided by the utility model is shown in the whole structure diagram Figure 2

[0018] Figure 3 The micro-flow reaction device provided by the utility model is shown in the cross-sectional view.

[0019] Figure 4 The cross-sectional view of the mixing cylinder provided by the utility model is shown.​​

[0020] The following are the labels in the diagram: 1. Reaction chamber; 2. Pump; 3. Input pipe; 4. First slow-flow pipe; 5. Mixing cylinder; 6. Second slow-flow pipe; 7. Output pipe; 8. Conduit; 9. Detection assembly; 10. Drain outlet; 11. Waste liquid tank; 12. Fixing column; 13. Drainage assembly; 14. First drainage block; 15. Second drainage block; 16. Inlet; 17. Outlet. Detailed Implementation

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] Please refer to the following: Figure 1 — Figure 4 ,in, Figure 1 Schematic diagram of the overall structure of the microflow reaction device provided by this utility model Figure 1 ; Figure 2 Schematic diagram of the overall structure of the microflow reaction device provided by this utility model Figure 2 ; Figure 3 A cross-sectional view of the microflow reaction device provided by this utility model; Figure 4 A cross-sectional view of the mixing cylinder provided by this utility model.

[0023] In specific implementation, a microflow reaction device has the following structure: Figure 1 — Figure 4 As shown, it includes: a reaction chamber 1 and a pumping unit 2. The pumping unit 2 is located on one side of the reaction chamber 1. An input pipe 3 is inserted through the side wall of the reaction chamber 1. A first slow-flow pipe 4 is bolted inside the reaction chamber 1. One end of the first slow-flow pipe 4 is bolted to the input pipe 3. The other end of the first slow-flow pipe 4 is bolted to a mixing cylinder 5. A second slow-flow pipe 6 is inserted through one side of the mixing cylinder 5. An output pipe 7 is inserted through one end of the second slow-flow pipe 6. The output pipe 7 passes through the side wall of the reaction chamber 1. Multiple conduits 8 are inserted inside the input pipe 3. The other ends of the multiple conduits 8 are all inserted into the pumping unit 2. A detection component 9 is bolted to one end of the output pipe 7. A drain outlet 10 is inserted through one side of the detection component 9. A waste liquid tank 11 is bolted to one side of the detection component 9.

[0024] It should be noted that the pumping member 2 is a peristaltic pump, and a plurality of conduits 8 are provided with one-way valves (not shown in the figure). When the solution is detected and mixed, the two groups of solutions are transported through the plurality of conduits 8 by the peristaltic pump. The solutions are preliminarily mixed at the input pipe 3. Since the conduits 8 are provided with one-way valves, the solution backflow can be avoided. The solution entering the input pipe 3 is transported into the mixing cylinder 5 through the first slow-flow pipe 4. The mixing cylinder 5 is provided with the fixed column 12. The fixed column 12 is fixedly connected with a plurality of drainage assemblies 13 on the side wall. The other end of the plurality of drainage assemblies 13 is fixedly connected to the inner side wall of the mixing cylinder 5. The plurality of drainage assemblies 13 are linearly arranged along the side wall of the fixed column 12. The solution is divided and then converged through the plurality of drainage assemblies 13, so that the solution is further mixed through multiple collisions, thereby making the solution reaction more sufficient. The fully mixed solution is transported into the detection assembly 9 through the second slow-flow pipe 6. The detection assembly 9 selects a detection instrument matched with the reaction. The solution after being detected by the detection instrument is discharged into the waste liquid tank 11 through the drain 10, thereby avoiding environmental pollution.

[0025] The bottom end of the first slow-flow pipe 4 is bifurcated, so that the solution forms a flow when entering the mixing cylinder 5, thereby making the solution collide with the top layer of the drainage assembly 13 to mix the solution for the first time.

[0026] The drainage assembly 13 includes the first drainage block 14 and the second drainage block 15. The first drainage block 14 is in the shape of a circular truncated cone and is fixedly connected to the side wall of the fixed column 12. The second drainage block 15 is in the shape of a circular column with a circular truncated cone-shaped through hole. The second drainage block 15 is fixedly connected to the inner side wall of the mixing cylinder 5.

[0027] It should be noted that when the solution enters the mixing cylinder 5, the solution is first divided by the first drainage block 14. The solution flows down along the side wall of the first drainage block 14 and flows to the second drainage block 15. The solution flows to the first drainage block 14 of the next layer through the second drainage block 15, so that the solution is mixed again by impact. The solution is mixed by impact for multiple times through the cooperation of the first drainage block 14 and the second drainage block 15, so that the solution is fully mixed, thereby reducing the setting of the spiral pipe and fully mixing the solution to make the reaction heat be fully released.

[0028] The reaction tank 1 is provided with an inlet 16 and an outlet 17 on the side wall. The outlet 17 is located above the inlet 16. The inlet 16 and the outlet 17 are provided with water stop valves (not shown in the figure).

[0029] It should be noted that the cooling liquid is injected into the reaction box 1 through the injection port 16 and is discharged through the flow port 17, and since the injection port 16 is located below the flow port 17, the cooling liquid can sufficiently cool the first slow-flow pipe 4, the second slow-flow pipe 6 and the mixing cylinder 5, thereby avoiding waste of the cooling liquid.

[0030] The first slow-flow pipe 4 and the second slow-flow pipe 6 are both spiral-shaped, so that the time of the elongated solution in the reaction box 1 is prolonged, the reaction is sufficient, and the spiral-shaped first slow-flow pipe 4 and the second slow-flow pipe 6 can increase the contact area with the cooling liquid, so that the cooling is more sufficient.

[0031] The circuit and the control involved in the utility model are prior art, and will not be described in detail here.

[0032] The above is only an embodiment of the utility model, and does not limit the patent range of the utility model, and any equivalent structure or equivalent process transformation using the contents of the utility model specification and drawings, or direct or indirect application in other related technical fields, are also included in the patent protection range of the utility model.

Claims

1. A microfluidic reaction device, characterized by, The utility model provides a reaction box (1), the input pipe (3) is inserted in the side wall of reaction box (1), and the first slow flow pipe (4) is detachably connected in reaction box (1), one end of first slow flow pipe (4) is detachably connected with input pipe (3), and the other end of first slow flow pipe (4) is detachably connected with the mixed cylinder (5) of multilayer design, the second slow flow pipe (6) is inserted in one side of mixed cylinder (5), one end of second slow flow pipe (6) is inserted with output pipe (7), and output pipe (7) passes through the side wall of reaction box (1).

2. The microfluidic reaction device of claim 1, wherein, The output pipe (7) is inserted with a plurality of conduits (8), and the other end of the plurality of conduits (8) is detachably connected to the pumping member (2); one end of the output pipe (7) is detachably connected to the detection assembly (9); one side of the detection assembly (9) is inserted with a drain (10); and one side of the detection assembly (9) is detachably connected to the waste liquid tank (11).

3. The microfluidic reaction device of claim 2, wherein, The mixed cylinder (5) is inserted with a fixed column (12), and a plurality of drainage assemblies (13) are fixedly connected to the side wall of the fixed column (12); the other end of the plurality of drainage assemblies (13) is fixedly connected to the inner side wall of the mixed cylinder (5); and the plurality of drainage assemblies (13) are linearly arranged along the side wall of the fixed column (12).

4. The microfluidic reaction device of claim 3, wherein, The drainage assembly (13) comprises a first drainage block (14) and a second drainage block (15); the first drainage block (14) is in the shape of a circular truncated cone; the first drainage block (14) is fixedly connected to the side wall of the fixed column (12); the second drainage block (15) is in the shape of a circular column with a circular truncated hole; and the second drainage block (15) is fixedly connected to the inner side wall of the mixed cylinder (5).

5. The microfluidic reaction device of claim 4, wherein, The side wall of the reaction box (1) is provided with an inlet (16) and an outlet (17); the outlet (17) is located above the inlet (16); and a water stop valve is arranged at the inlet (16) and the outlet (17).

6. The microfluidic reaction device of claim 5, wherein, The first slow flow pipe (4) and the second slow flow pipe (6) are in the shape of a spiral.

7. The microfluidic reaction device of claim 5, wherein, The pumping member (2) comprises a peristaltic pump.

8. The microfluidic reaction device of claim 5, wherein, A one-way valve is arranged in each of the plurality of conduits (8).

Citation Information

Patent Citations

  • Continuous flow microwave chemical reaction device

    CN221733306U