Raw material sample thawing cabinet

Abstract

The utility model discloses a raw material sample thawing cabinet which comprises a movable cabinet body, the single side of the cabinet body is an opening side, a plurality of layers of drawers are installed inside the cabinet body from top to bottom and installed in a draw-out mode from the cabinet door side, interlayers are arranged on the two side walls, corresponding to a cabinet door, of the cabinet body, air holes communicated with the interlayers are formed in the inner side wall of the cabinet body, and a circulation cavity is formed in the top of the cabinet body. The circulation cavity is communicated with the interlayers on the two sides, and a fan for promoting air flow and a heating device for heating air are installed in the circulation cavity. According to the equipment, flowing hot air is used for thawing, the air is heated by the top heating device, and then the hot air is guided into the cabinet body through the interlayer by the fan, so that the purpose of thawing a sample is achieved, a single-circulation air heating mode is adopted, air enters through the interlayer on one side of the cabinet body, and air is recycled through the interlayer on the other side; and the circulating cavity at the top is used for heating, so that the heat utilization rate is improved, the gas distribution effect is uniform, and the defrosting efficiency is improved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of biological preparation equipment, in particular to a raw material sample thawing cabinet. BACKGROUND

[0002] There are many types of vaccine drugs, among which inactivated antigens (such as inactivated viruses or bacteria) are one of the traditional vaccine forms. In recent years, mRNA vaccines as a new type of vaccine technology have attracted widespread attention and application.

[0003] The mRNA vaccine introduces mRNA encoding specific antigens into the human body, so that human cells can transcribe these mRNAs and produce corresponding antigen proteins, thereby stimulating the immune system to produce an immune response. The mRNA vaccine preparation process is roughly as follows: usually using E. coli as a carrier, plasmid DNA (pDNA) is obtained through fermentation, alkaline lysis and other processes, mRNA is obtained after enzyme cutting and in vitro transcription, and finally the product is prepared through lipid nanoparticle (LNP) technology. Each operation step is closely related, and all need to involve purification process. The upstream stage and the downstream stage are often not in the same laboratory, and there is also a time span. In order to ensure that the semi-finished product maintains absolute activity before processing, it is in frozen state during transportation, and the frozen sample needs to be thawed before downstream processing.

[0004] The constant temperature water bath box commonly used in the laboratory is thawed by water bath, and the thawing rate is too fast, which is not conducive to maintaining the activity of the sample. At the same time, the heat conduction carrier in the water bath box is water, which is easy to enter the sample and cause pollution. INVENTION CONTENTS

[0005] The utility model aims at providing a raw material sample thawing cabinet, and providing a hot air type thawing device.

[0006] To solve the above technical problems, the utility model is realized by the following technical schemes:

[0007] A raw material sample thawing cabinet, comprising a movable cabinet, the cabinet is open on one side, and is provided with a cabinet door which can be opened by turning over, a plurality of drawers are installed in the cabinet from top to bottom, the drawers are installed by pulling out from the side of the cabinet door, the upper side of the drawer is provided with a plurality of square partition layers for placing sample containers;

[0008] The two side walls of the cabinet corresponding to the cabinet door have a sandwich structure, the inner side wall of the cabinet has air holes communicating with the sandwich structure, and the top of the cabinet has a circulating cavity communicating with the two sandwich structures, a fan for promoting air flow and a heating device for heating air are installed in the circulating cavity.

[0009] Further, the circulating cavity is provided with a partition plate between the two sides of the interlayer, the partition plate is installed with an air guide pipe for communication, and the fan and the heating device are installed on the air guide pipe.

[0010] The drawer is provided with guide rails on both sides, and the cabinet body is provided with a sliding groove for supporting the guide rails and sliding on one side.

[0011] Further, the upper side of the drawer is detachably installed on the support plate, the partition layer is arranged on the support plate, the bottom of the drawer corresponding to the support plate is provided with a draining groove, and the support plate corresponding to the partition layer is provided with draining holes.

[0012] Further, the air holes are arranged in rows corresponding to the single-layer drawer, the air holes are rectangular openings, the inner side wall of the cabinet body is provided with a baffle corresponding to each row of air holes, the cabinet body is provided with a limiting groove corresponding to the upper and lower sides of the baffle, the baffle is installed on the side of the limiting groove and is provided with transverse movement, and the baffles are provided with hollow holes at intervals. The baffle corresponding to the side of the cabinet door is provided with a screw sleeve, the cabinet corresponding to the position of the cabinet door is provided with a screw rod, the screw rod is sleeved with the screw sleeve, and the screw rod is used for driving the baffle to move by rotating.

[0013] The device adopts hot air with fluidity to thaw, heats air through a top heating device, and then introduces the hot air into the cabinet body through the interlayer by the fan, so that the thawing purpose of the sample is achieved. The single-cycle air heating mode is adopted, air enters the cabinet body through one-side interlayer, air is recycled through the other-side interlayer, and then the air is heated through the top circulating cavity. Therefore, the heat utilization rate is improved, the air distribution effect is uniform, and the thawing efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS

[0014] In order to more clearly illustrate the technical scheme of the embodiment of the utility model, the following will be briefly introduced to the drawing needed to be used for the embodiment description.

[0015] Figure 1 The utility model discloses a structure schematic diagram.

[0016] Figure 2 The utility model discloses a drawer structure schematic diagram.

[0017] Figure 3 The utility model discloses a drawer disassembly structure schematic diagram.

[0018] Figure 4 The utility model discloses an air hole position structure schematic diagram.

[0019] In the drawings, the component list represented by each sign is as follows: cabinet body 1, drawer 2, partition layer 3, interlayer 4, air hole 12, circulating cavity 5, fan 51, partition plate 50, air guide pipe 52, guide rail 21, sliding groove 11, support plate 31, draining hole 32, baffle 6, limiting groove 13, screw sleeve 61, screw rod 14. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0021] like Figures 1-2 As shown: A raw material sample thawing cabinet includes a movable cabinet body 1. The bottom of the cabinet body is equipped with casters for easy movement in the laboratory. A push-pull bracket is installed on the side of the cabinet body. One side of the cabinet body 1 is open and equipped with a flip-open cabinet door. The cabinet door is hinged to the other side of the cabinet body. The cabinet door has a frame and inner glass for easy observation of the interior from the outside. Multiple drawers 2 are installed inside the cabinet body 1 from top to bottom. The drawers 2 are installed by pulling them out from the cabinet door side. The upper side of the drawers 2 has multiple square dividers 3 for placing sample containers. The upper side of the drawers has various diameter slots for placing containers of different diameters, such as Erlenmeyer flasks, beakers, and centrifuge tubes. The containers are secured in the slots to prevent them from tipping over.

[0022] The cabinet 1 has a double-layer 4 on both sides of the cabinet door. The inner side wall of the cabinet 1 has an air hole 12 that connects to the double-layer 4. The air holes are arranged in a row, with a single air hole corresponding to a single row of drawers. The top of the cabinet 1 has a circulation chamber 5 that connects to the double-layer 4 on both sides. A fan 51 that promotes airflow and a heating device for heating air are installed in the circulation chamber 5.

[0023] This equipment is used to store transported frozen samples. Before proceeding to the next step, thawing is required. Natural thawing requires a certain room temperature, which is often insufficient for rapid thawing in the laboratory. Laboratory-standard water baths, however, thaw samples too quickly, which is detrimental to maintaining sample activity. Furthermore, the water used as the heat transfer medium in the water bath can easily contaminate the samples.

[0024] This equipment uses flowing hot air for defrosting. The air is heated by a top heating device, and then a fan guides the hot air through the interlayer into the cabinet to achieve the purpose of defrosting the sample. It adopts a single-circulation air heating method, initiating air through one side of the cabinet interlayer and recovering air through the other side interlayer, and then heating it through the top circulation chamber. This not only improves the heat utilization rate, but also ensures uniform air distribution and improves defrosting efficiency.

[0025] like Figure 1As shown: the circulating cavity 5 is separated by the partition plate 50 between the two sides of the interlayer 4, the partition plate 50 is installed with the air guide pipe 52 for communication, the fan 51 and the heating device are installed on the air guide pipe 52. The heating device is a resistance wire heating device, which separates the circulating cavity through the partition plate, prevents the circulating cavity air from convection, and promotes the one-way circulation of air flow.

[0026] As shown in Figure 3 As shown: the drawer 2 has guide rails 21 on both sides, and the cabinet 1 has a sliding groove 11 on the side wall to support the guide rails 21 and slide on one side. It is convenient to pull out the drawer from the cabinet, and it is convenient to take samples and put samples.

[0027] As shown in Figure 2 As shown: the support plate 31 is detachably installed on the upper side of the drawer 2, the partition layer 3 is arranged on the support plate 31, the drawer 2 corresponds to the bottom of the support plate 31 and is a drain groove, and the support plate 31 corresponds to the partition layer and is provided with a drain hole 32. The sample reagent bottle will produce condensed water during thawing, and the condensed water can be introduced into the drain groove for unified treatment.

[0028] As shown in Figure 4 As shown: the air holes 12 are arranged in rows corresponding to the single-layer drawer 2, the air holes 12 are rectangular openings, the inner side wall of the cabinet 1 is provided with a baffle 6 corresponding to each row of air holes 12, the cabinet 1 is provided with a limiting groove 13 corresponding to the upper and lower sides of the baffle 6, for installing the side of the baffle 6 and providing horizontal movement, and the baffle 6 is provided with a hollow hole in a spaced manner. By moving the baffle to align the hollow hole with the air hole, the air hole can be completely released to maximize the air flow, or the air hole can be blocked to reduce the air flow. When there is no sample corresponding to the drawer, the corresponding air hole can be closed to reduce energy consumption. The baffle 6 corresponds to the side of the cabinet door and has a screw sleeve 61, the cabinet 1 is provided with a screw rod 14 corresponding to the position of the cabinet door, which is sleeved with the screw sleeve 61, and is used to drive the baffle 6 to move by rotating the screw rod 14.

[0029] The embodiments are selected and specifically described in the specification in order to better explain the principles and practical applications of the utility model, so that those skilled in the art can well understand and utilize the utility model.

Claims

1. A raw material sample freezing cabinet characterized by: Including movable cabinet (1), one side of the cabinet (1) is open side, and the cabinet door of the cabinet (1) is installed with the cabinet door of the cabinet (1), and the cabinet (1) is installed with multiple layers of drawers (2) from top to bottom, the drawer (2) is installed with the drawer (2) from the side of the cabinet door, the drawer (2) has multiple square partition layers (3) on the upper side, and the sample container is placed; The cabinet (1) has a sandwich layer (4) on the two sides of the side wall of the cabinet door, the inner side wall of the cabinet (1) has an air hole (12) communicating with the sandwich layer (4), the top of the cabinet (1) has a circulating cavity (5), the circulating cavity (5) is communicated with the two sandwich layers (4), the circulating cavity (5) is provided with a fan (51) for promoting air flow and a heating device for heating air.

2. The raw material sample freezing cabinet according to claim 1, characterized in that: The circulating cavity (5) is provided with a partition plate (50) between the two sandwich layers (4), the partition plate (50) is provided with a gas guide pipe (52) for communication, and the fan (51) and the heating device are installed in the gas guide pipe (52).

3. The sample freezer of claim 1, wherein: The drawer (2) has a guide rail (21) on both sides, and the side wall of the cabinet (1) has a sliding groove (11) for supporting the guide rail (21) and sliding on one side.

4. The sample freezer of claim 1, wherein: The drawer (2) is detachably installed with a support plate (31) on the upper side, the partition layer (3) is arranged on the support plate (31), and the drawer (2) is corresponding to the bottom of the support plate (31) is a drain groove, the support plate (31) corresponding to the partition layer is provided with a drain hole (32).

5. The sample freezer of claim 1, wherein: The air hole (12) is arranged in a row corresponding to the single layer drawer (2), the air hole (12) is a rectangular opening, the inner side wall of the cabinet (1) is provided with a baffle (6) corresponding to the single row air hole (12), the cabinet (1) is provided with a limiting groove (13) corresponding to the baffle (6) on the upper side, for installing the side of the baffle (6) and providing transverse movement, the baffle (6) is provided with a hollow hole in an interval.

6. A sample freezer as claimed in claim 5, wherein: The baffle (6) has a screw sleeve (61) corresponding to the side of the cabinet door, and the cabinet (1) is provided with a screw rod (14) corresponding to the position of the cabinet door, which is sleeved with the screw sleeve (61), so as to drive the baffle (6) to move through the rotation of the screw rod (14).

Images