Rapid dissolution equipment for detecting medicine
By using a combination of mesh plate and heat-conducting rod in the dissolution device, the problem of insufficient contact caused by drug floating was solved, thereby improving the drug dissolution speed and detection results.
Patent Information
- Application Number
- CN202423228307.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-26
- Publication Date
- 2025-12-30
- Estimated Expiration
- 2034-12-26
AI Technical Summary
In existing dissolution methods, the drug floats on the surface of the dissolution medium, resulting in insufficient contact, which affects the dissolution rate and the accuracy of the test results.
The drug is completely immersed in the dissolving medium using a mesh plate, and is uniformly heated by a combination of longitudinal and transverse heat-conducting rods, ensuring full contact between the drug and the medium and uniform temperature.
It improves the drug dissolution rate and the accuracy of dissolution detection, ensuring sufficient contact between the drug and the dissolution medium and temperature uniformity.
Smart Images

Figure CN223742129U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to the technical field of medicine detection, and specifically relates to a rapid dissolving equipment for detecting medicine. BACKGROUND
[0002] Detecting medicine can ensure medicine quality and guarantee medicine safety, and medicine detection and dissolution mainly aim at evaluating the quality and performance of medicine preparation, and the speed and degree of medicine dissolution will directly affect the absorption, distribution, metabolism and excretion process of medicine in the body, if the solubility of medicine is too low or the dissolution speed is too slow, the medicine can not be fully absorbed, thereby affecting the treatment effect, the existing dissolution method is to put medicine into a dissolution medium, adjust the temperature of the dissolution medium to simulate the dissolution speed of medicine in the stomach, but in the dissolution process, medicine can float on the surface of the dissolution medium, so that the contact between medicine and the dissolution medium is insufficient, the dissolution speed is affected, and after the dissolution medium is heated, the temperature of the uppermost and edge positions is lower than that of other positions, thereby affecting the detection and dissolution result. UTILITY MODEL CONTENT
[0003] The utility model provides a rapid dissolving equipment for detecting medicine, which has the characteristics that medicine can be completely soaked in the dissolution medium through the net plate, and the temperature difference of each position of the dissolution medium can be reduced through the heat conduction of the longitudinal heat conduction rod one, the horizontal heat conduction rod one, the longitudinal heat conduction rod two and the horizontal heat conduction rod two.
[0004] The utility model provides the following technical scheme: including heating base, the top of heating base is equipped with the dissolving cylinder, the top of dissolving cylinder is connected with the movable ring, the bottom of movable ring is equipped with a plurality of connecting rods, the bottom of connecting rod is equipped with the net plate, the top of heating base is equipped with two longitudinal heat conduction rod one, two longitudinal heat conduction rod one top is connected through horizontal heat conduction rod one, be equipped with two longitudinal heat conduction rod two on the net plate, two longitudinal heat conduction rod two top is connected through horizontal heat conduction rod two.
[0005] Wherein, the longitudinal heat conduction rod one and the horizontal heat conduction rod one are located in the inner side of the dissolving cylinder, and the two ends of the horizontal heat conduction rod one are fixedly connected with the two longitudinal heat conduction rod one respectively.
[0006] Wherein, the bottom of the movable ring is provided with a fixed rod, and the bottom of the fixed rod is provided with an adjusting plate.
[0007] Wherein, there is a gap between the connecting rod and the fixed rod, and the gap between the connecting rod and the fixed rod matches the thickness of the dissolving cylinder.
[0008] Two through grooves are formed in the net plate, and the longitudinal heat conduction rod two is fixedly connected to the inner side of the through grooves.
[0009] The longitudinal heat conduction rod two is located at the top of the net plate, and the distance between the longitudinal heat conduction rod two and the dissolving cylinder is less than the distance between the longitudinal heat conduction rod one and the dissolving cylinder.
[0010] The longitudinal heat conduction rod two is located at the top of the net plate, and the distance between the longitudinal heat conduction rod two and the dissolving cylinder is less than the distance between the longitudinal heat conduction rod one and the dissolving cylinder.
[0011] The longitudinal heat conduction rod two is located at the top of the net plate, and the distance between the longitudinal heat conduction rod two and the dissolving cylinder is less than the distance between the longitudinal heat conduction rod one and the dissolving cylinder. The longitudinal heat conduction rod two is located at the top of the net plate, and the distance between the longitudinal heat conduction rod two and the dissolving cylinder is less than the distance between the longitudinal heat conduction rod one and the dissolving cylinder.
[0012] The longitudinal heat conduction rod two is located at the top of the net plate, and the distance between the longitudinal heat conduction rod two and the dissolving cylinder is less than the distance between the longitudinal heat conduction rod one and the dissolving cylinder. BRIEF DESCRIPTION OF DRAWINGS
[0013] Figure 1 It is a three-dimensional structure schematic view of the utility model;
[0014] Figure 2 It is an explosion structure schematic view of the utility model;
[0015] Figure 3 It is the A part enlarged view in the utility model Figure 2
[0016] Figure 4 It is a cross section structure schematic view of the utility model;
[0017] In the figure: 1, heating base; 11, dissolving cylinder; 12, longitudinal heat conduction rod one; 121, transverse heat conduction rod one; 2, movable ring; 21, connecting rod; 22, fixed rod; 221, adjusting plate; 3, net plate; 31, through groove; 32, longitudinal heat conduction rod two; 321, transverse heat conduction rod two. DETAILED DESCRIPTION
[0018] Please refer to Figures 1-4The utility model provides following technical scheme: including heating base 1, the top of heating base 1 is equipped with dissolving cylinder 11, the top of dissolving cylinder 11 is connected with movable ring 2, the bottom of movable ring 2 is equipped with a plurality of connecting rods 21, the bottom of connecting rod 21 is equipped with screen plate 3, the top of heating base 1 is equipped with two longitudinal heat conduction rods one 12, the top of two longitudinal heat conduction rods one 12 is connected through horizontal heat conduction rod one 121, and two longitudinal heat conduction rods two 32 are equipped on screen plate 3, and the top of two longitudinal heat conduction rods two 32 is connected through horizontal heat conduction rod two 321.
[0019] In the embodiment: including heating base 1, the heating base 1 can be heated by the heating base 1 above the dissolution medium, and make the dissolution medium stable at about thirty-seven degrees, the top of heating base 1 is provided with dissolving cylinder 11, dissolving cylinder 11 is fixedly connected with heating base 1, by pouring the dissolving medium into the inside of dissolving cylinder 11, can make heating base 1 to heating base 1 inside the dissolving medium is heated, the top of dissolving cylinder 11 is movably connected with movable ring 2, movable ring 2 is matched with the size of dissolving cylinder 11, movable ring 2 can be directly placed on the top of dissolving cylinder 11, the bottom of movable ring 2 is provided with a plurality of connecting rods 21, a plurality of connecting rods 21 are fixedly connected with movable ring 2, and connecting rod 21 is perpendicular to movable ring 2, when movable ring 2 is connected with dissolving cylinder 11, connecting rod 21 will be located in the inside of dissolving cylinder 11, and contact with the inner wall of dissolving cylinder 11, the bottom of connecting rod 21 is provided with screen plate 3, the top of screen plate 3 is fixedly connected with a plurality of connecting rods 21, and screen plate 3 is matched with the inner diameter size of dissolving cylinder 11, through the connection of movable ring 2 and dissolving cylinder 11, screen plate 3 will enter the inside of dissolving cylinder 11, when screen plate 3 is immersed in the dissolving medium, the medicine can be pressed downward through screen plate 3, so that the medicine is completely soaked in the dissolving medium, thereby facilitating to ensure the full contact of the medicine and the dissolving medium, ensuring the dissolution speed of the medicine, the top of heating base 1 is provided with two longitudinal heat conduction rods one 12, longitudinal heat conduction rod one 12 is fixedly connected with heating base 1, and the length of longitudinal heat conduction rod one 12 is less than the distance between heating base 1 and screen plate 3, therefore, screen plate 3 will not contact with longitudinal heat conduction rod one 12 after entering the inside of dissolving cylinder 11, the top of two longitudinal heat conduction rods one 12 is connected through horizontal heat conduction rod one 121, horizontal heat conduction rod one 121 is parallel to heating base 1, heat can be transferred through longitudinal heat conduction rod one 12 and horizontal heat conduction rod one 121, screen plate 3 is provided with two longitudinal heat conduction rods two 32, two longitudinal heat conduction rods two 32 are parallel to each other, when screen plate 3 is immersed in the dissolving medium, the bottom of longitudinal heat conduction rod two 32 will contact with the top of heating base 1, so that longitudinal heat conduction rod two 32 transmits the heat of heating base 1 upward, the top of two longitudinal heat conduction rods two 32 is connected through horizontal heat conduction rod two 321, horizontal heat conduction rod two 321 is located above screen plate 3, through the connection of horizontal heat conduction rod two 321 and longitudinal heat conduction rod two 32, heat can be transmitted to the top of dissolving medium through longitudinal heat conduction rod two 32 and horizontal heat conduction rod two 321, and the heat conductivity of horizontal heat conduction rod two 321 and longitudinal heat conduction rod two 32 is greater than that of horizontal heat conduction rod one 121 and longitudinal heat conduction rod one 12, therefore, the temperature difference of each position of the dissolving medium can be reduced through the heat conduction of longitudinal heat conduction rod one 12, horizontal heat conduction rod one 121, longitudinal heat conduction rod two 32 and horizontal heat conduction rod two 321, thereby facilitating to ensure the accuracy of the medicine dissolution detection.
[0020] The longitudinal heat conduction rod 12 and the transverse heat conduction rod 121 are located on the inner side of the dissolving cylinder 11, and the two ends of the transverse heat conduction rod 121 are fixedly connected with the two longitudinal heat conduction rods 12 respectively; the heat of the heating base 1 is transmitted through the longitudinal heat conduction rod 12 and the transverse heat conduction rod 121, so as to reduce the temperature difference between the dissolving medium and the heating base 1.
[0021] The bottom of the movable ring 2 is provided with a fixed rod 22, and the bottom of the fixed rod 22 is provided with an adjusting plate 221; the fixed rod 22 is fixedly connected with the movable ring 2, and the fixed rod 22 is perpendicular to the movable ring 2; the adjusting plate 221 is fixedly connected with the fixed rod 22, and the movable ring 2 is moved through the adjusting plate 221.
[0022] The gap between the connecting rod 21 and the fixed rod 22 matches the thickness of the dissolving cylinder 11; when the movable ring 2 is located at the top of the dissolving cylinder 11, the connecting rod 21 and the fixed rod 22 are located on the inner side and the outer side of the dissolving cylinder 11 respectively.
[0023] Two through grooves 31 are formed in the mesh plate 3, and longitudinal heat conduction rods 32 are fixedly connected on the inner side of the through grooves 31; the longitudinal heat conduction rods 32 are perpendicular to the mesh plate 3, and the bottom of the longitudinal heat conduction rod 32 is in contact with the heating base 1 when the movable ring 2 is located at the top of the dissolving cylinder 11.
[0024] The transverse heat conduction rod 321 is located at the top of the mesh plate 3, and the distance between the longitudinal heat conduction rod 32 and the dissolving cylinder 11 is less than the distance between the longitudinal heat conduction rod 12 and the dissolving cylinder 11; when the mesh plate 3 is immersed in the dissolving medium, the longitudinal heat conduction rod 32 is located at the edge of the dissolving medium, and the transverse heat conduction rod 321 is located at the top of the dissolving medium.
[0025] The transverse heat conduction rod 121 is not in contact with the mesh plate 3, and the two ends of the transverse heat conduction rod 321 are fixedly connected with the two longitudinal heat conduction rods 32 respectively; through the pressing of the mesh plate 3 on the medicine, the medicine is located above the transverse heat conduction rod 121 and below the transverse heat conduction rod 321, which is beneficial to ensure that the temperature of the dissolving medium around the medicine is close to the heating base 1.
[0026] The working principle and use flow of the utility model are: in use, first, pour the dissolving medium into the inside of the dissolving cylinder 11, then make the temperature of the dissolving medium rise through the heating base 1 and keep at about thirty-seven degrees, then put the medicine into the inside of the dissolving cylinder 11, then put the movable ring 2 on the top of the dissolving cylinder 11, and the net plate 3 will enter the inside of the dissolving cylinder 11, when the net plate 3 is immersed in the dissolving medium, the medicine will be pressed downward, so that the medicine is completely soaked in the dissolving medium, at the same time, the bottom of the longitudinal heat conduction rod two 32 will contact with the top of the heating base 1, through the connection of the horizontal heat conduction rod two 321 and the longitudinal heat conduction rod two 32, the heat can be transmitted to the top of the dissolving medium through the longitudinal heat conduction rod two 32 and the horizontal heat conduction rod two 321, and the heat conductivity of the horizontal heat conduction rod two 321 and the longitudinal heat conduction rod two 32 is greater than that of the horizontal heat conduction rod one 121 and the longitudinal heat conduction rod one 12, therefore, through the heat conduction of the longitudinal heat conduction rod one 12, the horizontal heat conduction rod one 121, the longitudinal heat conduction rod two 32 and the horizontal heat conduction rod two 321, the temperature difference of each position of the dissolving medium can be reduced.
Claims
1. A rapid dissolution apparatus for detecting a drug comprising a heating base (1) characterized in that: The top of the heating base (1) is provided with a dissolving cylinder (11), the top of the dissolving cylinder (11) is movably connected with a movable ring (2), the bottom of the movable ring (2) is provided with a plurality of connecting rods (21), the bottom of the connecting rod (21) is provided with a mesh plate (3), the top of the heating base (1) is provided with two longitudinal heat conduction rods (12), the top of the two longitudinal heat conduction rods (12) is connected through a transverse heat conduction rod (121), the mesh plate (3) is provided with two longitudinal heat conduction rods (32), the top of the two longitudinal heat conduction rods (32) is connected through a transverse heat conduction rod (321).
2. The rapid dissolution apparatus for detecting a drug according to claim 1, wherein: The longitudinal heat conduction rod (12) and the transverse heat conduction rod (121) are located on the inner side of the dissolving cylinder (11), and the two ends of the transverse heat conduction rod (121) are fixedly connected with the two longitudinal heat conduction rods (12) respectively.
3. The rapid dissolution apparatus for detecting a drug according to claim 2, wherein: The bottom of the movable ring (2) is provided with a fixed rod (22), and the bottom of the fixed rod (22) is provided with an adjusting plate (221).
4. The rapid dissolution apparatus for detecting a drug according to claim 3, wherein: There is a gap between the connecting rod (21) and the fixed rod (22), and the gap between the connecting rod (21) and the fixed rod (22) matches the thickness of the dissolving cylinder (11).
5. The rapid dissolution apparatus for detecting a drug according to claim 4, wherein: Two through grooves (31) are formed in the mesh plate (3), and the longitudinal heat conduction rods (32) are fixedly connected on the inner side of the through grooves (31).
6. The rapid dissolution apparatus for detecting a drug according to claim 5, wherein: The transverse heat conduction rod (321) is located on the top of the mesh plate (3), and the distance between the longitudinal heat conduction rod (32) and the dissolving cylinder (11) is less than the distance between the longitudinal heat conduction rod (12) and the dissolving cylinder (11).
7. The rapid dissolution apparatus for detecting a drug according to claim 6, wherein: The transverse heat conduction rod (121) does not contact the mesh plate (3), and the two ends of the transverse heat conduction rod (321) are fixedly connected with the two longitudinal heat conduction rods (32) respectively.