High-sensitivity flow antibody quantitative detection kit

Abstract

The utility model provides a high sensitivity flow type antibody quantitative detection suite, relates to medical supplies technical field, including test paper, solution bag, dipping cotton swab, anti-collision box and quantitation subassembly, dipping cotton swab middle is equipped with the middle folding groove, quantitation subassembly includes test tube and cambered surface piece, cambered surface piece bottom is fixed with the fixed rubber ring, and the fixed rubber ring is fixed in the middle folding groove. A mode of installing a pressing rubber ring is adopted to solve the problem of flow antibody detection, which is an advanced immunoassay technology, a common user can also carry out self-test at home, the test suite generally comprises all necessary materials and instructions, so that the user can collect and analyze a blood sample through simple steps, but under the condition of no professional guidance, the test suite has the advantages of simple operation and low cost. In the prior art, the risk of operation errors exists, a user is difficult to master the dropping amount of a solution to test paper after sampling blood and dropping the blood into a medical solvent, if the dropping amount of the blood is too small or too large, the reagent reaction is incomplete, the final detection result is influenced, the test result is inaccurate, and the sensitivity is reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical supplies technical field especially, relates to high sensitivity flow type antibody quantitative detection kit. BACKGROUND

[0002] Flow type antibody quantitative detection kit is a kind of biological analysis tool based on flow cytometry, for the quantitative detection of the existence and expression level of specific protein or molecule on cell surface or in cell.Flow type antibody quantitative detection kit has the advantages such as high sensitivity, high specificity, high throughput and automation, can be used for the diagnosis of various diseases in the field of cell biology, immunology, pathology etc., with the continuous progress of technology and the expansion of application field, the development prospect of flow type antibody quantitative detection kit is very broad.In the future, this technology is expected to become one of important tools for clinical diagnosis and treatment, and make greater contribution to human health cause.

[0003] In prior art, flow type antibody detection is an advanced immunological analysis technology, with the development of medical technology, some flow type antibody detection kits have been designed to be simple enough that ordinary users can also self-test at home, these test kits usually include all necessary materials and instructions, so that users can collect blood samples and analyze by simple steps, but there is the risk of operation error without professional guidance, after users collect blood and drop blood drop into medical solvent, it is difficult to master the drop amount of solution to test paper, if the amount of blood drop is too little or too much, it will lead to incomplete reagent reaction, affect the final detection result, lead to inaccurate test result, reduce sensitivity. UTILITY MODEL CONTENT

[0004] The utility model aims at solving the shortcomings in prior art, and provides high sensitivity flow type antibody quantitative detection kit.

[0005] To achieve the above objectives, this utility model adopts the following technical solution: a high-sensitivity flow cytometry antibody quantitative detection kit, including test strips, solution bags, swabs, a shockproof box, and a quantitative component. The swabs have a central fold groove in the middle. The quantitative component includes a test tube and an arc-shaped component. A fixed rubber ring is fixed to the bottom of the arc-shaped component. A slider is slidably connected to the inner wall of the arc-shaped component. A pressing rubber ring is fixed to the bottom of the slider. A pressing button is fixed to the top of the slider. Wings are fixed in a circumferential array on the circumference of the arc-shaped component. In the prior art, flow cytometry antibody detection is an advanced immunoassay technique. With the development of medical technology, some flow cytometry antibody detection kits have been designed to be simple enough for ordinary users to perform self-testing at home. These kits usually include all the necessary materials and instructions, allowing users to collect blood samples and perform analysis through simple steps. However, without professional guidance, there is a risk of operational errors. After collecting blood and adding it to the medical solvent, it is difficult for users to... The amount of solution added to the test strip is crucial. Too little or too much blood can lead to incomplete reagent reaction, affecting the final test results and causing inaccuracy and reduced sensitivity. To address this issue, this invention employs a pressing rubber ring. When using the test strip, the user simply dips a cotton swab in blood, holds both ends, breaks the swab through the central fold groove, places the blood-collecting end into the test tube, pours the solution from the solution bag into the test tube, shakes the tube to mix the blood and solution thoroughly, slides the fixing rubber ring into one end of the test tube, aligns the other end of the test tube with the test strip opening, supports the wing plate with the index and middle fingers, and presses the button with the thumb. This causes the pressing rubber ring to slide downwards while maintaining an airtight seal, allowing the mixed solution to flow out from the pre-drilled opening at the bottom of the test tube. When the user presses the button to the curved surface, the appropriate amount of solution is dispensed. This allows users to perform quantitative testing easily, improving the sensitivity of the test strip.

[0006] Preferably, a side track is provided at the top of the inner wall of the anti-collision box. A hard rounded corner insert is fixed at one end of the inner wall of the side track. A side track plate is slidably connected to the inner wall of the side track. A flexible rounded corner insert is fixed on one side of the side track plate, and a box sliding cover is fixed on the other side of the side track plate. In the prior art, the test kit is made of plastic. During transportation, the test paper and cotton swabs are easily bent and damaged by collisions, resulting in a decrease in the sensitivity of the product during testing. To address this problem, this utility model solves the problem by installing an anti-collision box. When the operator is securing the test kit, the kit is placed in the anti-collision box for fixation. Then, the side track plate is slid into the side track. When the flexible rounded corner insert of the side track plate comes into contact with the hard rounded corner insert, it deforms until the box sliding cover reaches one end of the anti-collision box. The flexible rounded corner insert and the hard rounded corner insert are nested together, so that the box sliding cover and the anti-collision box do not slide, thereby improving the stability of the product.

[0007] Preferably, the bottom of the anti-collision box is fixed with reinforcing ribs, and the inner wall of the anti-collision box is fixed with baffles. In the prior art, the anti-collision box is a polymer product, which is brittle and easily damaged during transportation. At the same time, the solution bag is easily damaged by impact and has low puncture resistance, resulting in a high product defect rate. To address these problems, this utility model solves the problem by installing reinforcing ribs. The reinforcing ribs prevent the anti-collision box from bending and being damaged during transportation. At the same time, the baffles prevent the solution bag from leaving the inner wall of the anti-collision box, and the baffles cover the solution bag, so that most of the solution bag area is covered by the baffles, avoiding some puncture damage, thereby improving the product yield.

[0008] Preferably, the top of the sliding cover of the box is provided with a friction-enhancing groove to increase friction and improve the user experience.

[0009] Preferably, the bottom of the wing plate is provided with a finger groove, which makes it easier for users to grip the wing plate and improves the user experience.

[0010] Preferably, the inner wall of the anti-collision box is provided with a finger support groove, which makes it easier for users to take out the product and improves the user experience.

[0011] Preferably, the four corners of the anti-collision box are rounded to prevent scratches to users and improve user experience.

[0012] Beneficial effects

[0013] 1. In existing technologies, flow cytometry antibody detection is an advanced immunoassay technique. With the development of medical technology, some flow cytometry antibody detection kits have been designed to be simple enough for ordinary users to perform self-testing at home. These kits typically include all the necessary materials and instructions, allowing users to collect blood samples and perform analysis through simple steps. However, without professional guidance, there is a risk of operational errors. After collecting blood and adding it to the medical solvent, users may find it difficult to control the amount of solution added to the test strip. If too little or too much blood is added, the reagent reaction may be incomplete, affecting the final test results and leading to inaccurate results and reduced sensitivity. To address this problem, this invention employs the installation of a pressure-activated rubber ring. This method solves the problem by having the user dip a cotton swab in blood, hold both ends of the swab, break it through the central fold, place the blood-collecting end into the test tube, pour the solution from the solution bag into the test tube, shake the test tube to mix the blood and solution thoroughly, slide the retaining ring into one end of the test tube, align the other end of the test tube with the test strip opening, support the flaps with the index and middle fingers, and press the button with the thumb to slide the retaining ring downwards while maintaining an airtight seal, allowing the mixed solution to flow out from the pre-drilled opening at the bottom of the test tube. When the user presses the button to the curved surface, the appropriate amount of solution is obtained, allowing users to perform quantitative testing in a simple way, thus improving the sensitivity of the test strip.

[0014] 2. In the prior art, the testing kit is made of plastic. During transportation, the test strips and cotton swabs are easily bent and damaged by collisions, resulting in reduced sensitivity during testing. To address this problem, this utility model uses an anti-collision box. When the operator is securing the testing kit, the kit is placed in the anti-collision box for fixation. Then, the side rail plate is slid into the side rail. When the flexible rounded corner insert of the side rail plate comes into contact with the hard rounded corner insert, it deforms until the sliding cover of the box reaches one end of the anti-collision box. The flexible rounded corner insert and the hard rounded corner insert nest together, preventing the sliding cover of the box from sliding with the anti-collision box, thus improving the stability of the product.

[0015] 3. In the prior art, the anti-collision box is a polymer product with high brittleness, which is easily damaged during transportation. At the same time, the solution bag is easily damaged by impact and has low puncture resistance, resulting in a high product defect rate. To address these issues, this utility model adopts the method of installing reinforcing ribs. The reinforcing ribs prevent the anti-collision box from bending and being damaged during transportation. At the same time, the baffle prevents the solution bag from leaving the inner wall of the anti-collision box, and the baffle covers most of the solution bag, avoiding some puncture damage and improving the product yield. Attached Figure Description

[0016] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0017] Figure 2 This is a three-dimensional structural diagram of the reinforcing rib of this utility model;

[0018] Figure 3 This is a three-dimensional structural diagram of the flexible rounded corner insert of this utility model;

[0019] Figure 4 This is a three-dimensional structural diagram of the hard rounded corner insert of this utility model;

[0020] Figure 5 This is a three-dimensional structural diagram of the baffle of this utility model;

[0021] Figure 6 This is a three-dimensional structural diagram of the pressure rubber ring of this utility model.

[0022] Legend:

[0023] 1. Test strip; 101. Solution bag; 102. Soaking swab; 2. Center fold groove; 201. Test tube; 202. Curved surface part; 203. Wing plate; 204. Fixed rubber ring; 205. Sliding rod; 206. Pressing rubber ring; 207. Press button; 208. Finger groove; 3. Anti-collision box; 301. Side rail; 302. Side rail plate; 303. Flexible rounded corner insert; 304. Box sliding cover; 305. Hard rounded corner insert; 306. Friction-enhancing groove; 307. Rounded corner edge; 308. Reinforcing rib; 4. Baffle; 401. Finger support groove. Detailed Implementation

[0024] To make the technical means, creative features, and achieved objectives and effects of this utility model easier to understand, the present utility model is further described below with reference to specific embodiments and accompanying drawings. However, the following embodiments are merely preferred embodiments of this utility model and not all of them. Other embodiments obtained by those skilled in the art based on the embodiments described in the implementation plan without creative effort are all within the protection scope of this utility model.

[0025] The specific embodiments of this utility model are described below with reference to the accompanying drawings. Specific implementation examples:

[0027] Reference Figures 1-6A high-sensitivity flow cytometry antibody quantitative detection kit includes a test strip 1, a solution bag 101, a swab 102, a shockproof box 3, and a quantitative component. The swab 102 has a central fold groove 2 in its middle. The quantitative component includes a test tube 201 and an arc-shaped component 202. A retaining ring 204 is fixed to the bottom of the arc-shaped component 202. A slider 205 is slidably connected to the inner wall of the arc-shaped component 202. A pressing ring 206 is fixed to the bottom of the slider 205. A pressing button 207 is fixed to the top of the slider 205. Wings are fixed in a circular array on the circumference of the arc-shaped component 202. Flow cytometry antibody detection is an advanced immunoassay technique. With advancements in medical technology, some flow cytometry antibody detection kits have been designed to be simple enough for ordinary users to perform self-tests at home. These kits typically include all necessary materials and instructions, allowing users to collect and analyze blood samples through simple steps. However, without professional guidance, there is a risk of operational errors. After collecting blood and adding it to the medical solvent, users may struggle to control the amount of solution added to the test strip. Too little or too much blood can lead to incomplete reagent reactions, affecting the final test results and causing inaccurate results and reduced sensitivity. This is addressed by installing a pressure-adjustable rubber ring 206. When using the kit, the user dips a cotton swab 102 in the blood, pinches both ends of the swab, breaks it through the central fold groove 2, places the blood-collecting end into the test tube 201, pours the solution from the solution bag 101 into the test tube 201, shakes the test tube 201 to thoroughly mix the blood and solution, and then inserts the pressure-adjustable rubber ring 206. 4. Slide one end of the test tube 201, align the other end of the test tube 201 with the test strip opening of the test strip 1, support the wing plate 203 with your index and middle fingers, and press the button 207 with your thumb. This causes the pressure ring 206 to slide downwards while maintaining airtightness, allowing the mixed solution to flow out from the pre-drilled opening at the bottom of the test tube 201. When the user presses the button 207 to the curved surface 202, the appropriate solution volume is reached, allowing the user to perform quantitative testing in a simple way, thus improving the sensitivity of the test strip. A finger groove 208 is provided at the bottom of the wing plate 203 for easy gripping and improved user experience.

[0028] The top of the inner wall of the anti-collision box 3 has a side rail 301. A hard rounded corner insert 305 is fixed to one end of the inner wall of the side rail 301. A side rail plate 302 is slidably connected to the inner wall of the side rail 301. A flexible rounded corner insert 303 is fixed to one side of the side rail plate 302. A box sliding cover 304 is fixed to the other side of the side rail plate 302. The detection kit is made of plastic. During transportation, the test paper 1 and the cotton swab 102 are easily bent and damaged by impact, which reduces the sensitivity of the product during detection. Therefore, the anti-collision box is installed. The solution using Box 3 involves placing the test kit into the anti-collision box 3 for fixation when the operator is ensuring the kit is secure. Then, the side rail plate 302 slides into the side rail 301. When the flexible rounded corner insert 303 of the side rail plate 302 contacts the hard rounded corner insert 305, deformation occurs until the sliding cover 304 reaches one end of the anti-collision box 3. The flexible rounded corner insert 303 and the hard rounded corner insert 305 nest together, preventing slippage between the sliding cover 304 and the anti-collision box 3, thus improving product stability. The top of the sliding cover 304 has a friction-enhancing groove 306 to increase friction and improve user experience. The bottom of the anti-collision box 3 is fixed with reinforcing ribs 308, and the inner wall of the anti-collision box 3 is fixed with baffles 4. The anti-collision box 3 is a polymer product, which is relatively brittle and easily damaged during transportation. Simultaneously, the solution bag 101 is easily damaged by impact and has low puncture resistance, resulting in a high product defect rate. The installation of reinforcing ribs 308 solves this problem, preventing the anti-collision box 3 from bending and being damaged during transportation. At the same time, the baffles 4 prevent the solution bag 101 from leaving the inner wall of the anti-collision box 3, and the baffles 4 cover most of the solution bag 101, avoiding some puncture damage and improving the product yield. The inner wall of the anti-collision box 3 has finger support grooves 401, making it easier for users to remove the product and improving the user experience. The four corners of the anti-collision box 3 are rounded edges 307 to prevent scratches to users and improve the user experience.

[0029] The working principle of this utility model is as follows: When the user uses it, they dip a cotton swab 102 to collect blood, then pinch both ends of the cotton swab 102 and break it off through the central fold groove 2. One end of the blood collection is placed into the test tube 201, and the solution in the solution bag 101 is poured into the test tube 201. The test tube 201 is shaken to mix the blood and solution thoroughly. The fixing ring 204 is then slid into one end of the test tube 201. The user aligns the other end of the test tube 201 with the test strip opening of the test strip 1, supports the wing plate 203 with their index and middle fingers, and presses the pressing button 207 with their thumb. This causes the pressing ring 206 to slide downward while maintaining airtightness, allowing the mixed solution to flow out from the pre-opened opening at the bottom of the test tube 201. When the user presses the pressing button 207 to the arc surface 202, the appropriate amount of solution is obtained, allowing the user to perform quantitative testing in a simple way.

[0030] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A high-sensitivity flow antibody quantitative detection kit, comprising a test paper (1), a solution bag (101), a dipstick (102), an anti-collision box (3) and a quantitative assembly, characterized in that: The middle of the dip cotton swab (102) is provided with a middle folding groove (2), the quantitative assembly comprises a test tube (201) and an arc surface piece (202), the bottom of the arc surface piece (202) is fixedly provided with a fixed rubber ring (204), the inner wall of the arc surface piece (202) is slidably connected with a sliding rod (205), the bottom of the sliding rod (205) is fixedly provided with a pressure rubber ring (206), the top of the sliding rod (205) is fixedly provided with a pressing button (207), and the circumferential surface of the arc surface piece (202) is fixedly provided with a wing plate (203) in an array.

2. The high sensitivity flow antibody quantitative detection kit according to claim 1, characterized in that: The inner wall of the anti-collision box (3) is provided with a side rail (301) at the top end, the inner wall of the side rail (301) is fixedly provided with a hard round corner insert (305) at one end, the inner wall of the side rail (301) is slidably connected with a side rail plate (302), one side of the side rail plate (302) is fixedly provided with a flexible round corner insert (303), and the other side of the side rail plate (302) is fixedly provided with a box sliding cover (304).

3. The high sensitivity flow antibody quantitative detection kit according to claim 1, characterized in that: The bottom of the anti-collision box (3) is fixedly provided with a reinforcing rib (308), and the inner wall of the anti-collision box (3) is fixedly provided with a baffle (4).

4. The high sensitivity flow antibody quantitative detection kit according to claim 2, characterized in that: The top of the box sliding cover (304) is provided with a friction increasing groove (306).

5. The high sensitivity flow antibody quantitative detection kit according to claim 1, characterized in that: The bottom of the wing plate (203) is provided with a finger groove (208).

6. The high sensitivity flow antibody quantitative detection kit according to claim 1, characterized in that: The inner wall of the anti-collision box (3) is provided with a finger supporting groove (401).

7. The high sensitivity flow antibody quantitative detection kit according to claim 1, characterized in that: The four corners of the anti-collision box (3) are provided with round corner edges (307).

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