Pelletizing equipment for biological pharmacy

Abstract

The utility model relates to the technical field of biopharmacy granulation, in particular to biopharmacy granulation equipment which comprises an equipment case, a supporting table column is fixedly mounted at the top of the equipment case, an annular grinding knife is rotatably mounted on the top surface of the supporting table column, a material receiving box is detachably mounted on the outer side of the supporting table column, and the material receiving box is detachably mounted on the outer side of the supporting table column. The outer side of the annular grinding cutter is sleeved with two semicircular barrel shells, and a plurality of screen holes are evenly formed in the outer sides of the semicircular barrel shells. According to the utility model, the two semicircular barrel shells are spliced to form the annular screen barrel, the annular grinding cutter rotates to extrude raw materials into the screen holes of the screen barrel to form granular medicines, and the two semicircular barrel shells are unfolded in the directions opposite to each other after granulation is completed, so that the inner side screen holes and the outer side screen holes of the semicircular barrel shells are exposed; therefore, the inner side screen holes and the outer side screen holes of the screen drum are exposed outdoors, a user can conveniently and directly clean raw materials attached to the inner sides and the outer sides of the screen holes, and the screen hole cleaning efficiency can be improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of biopharmaceutical granulation, and particularly relates to a granulation equipment for biopharmaceuticals. BACKGROUND

[0002] The rotary granulator is a commonly used biopharmaceutical granulation equipment, and mainly comprises a bin, a stainless steel sieve cylinder fixedly connected to the bottom of the bin, and a ring mill installed rotatably at the inner bottom of the stainless steel sieve cylinder.

[0003] After granulation of a certain kind of medicine is completed, granular materials may be adhered to the sieve holes, and the materials adhered to the sieve holes on the outer side of the sieve cylinder can be directly cleaned by hand, but the materials adhered to the sieve holes on the inner side of the sieve cylinder are inconvenient to clean, which affects the cleaning efficiency of the adhered materials on the sieve cylinder. UTILITY MODEL CONTENTS

[0004] The utility model aims to provide a granulation equipment for biopharmaceuticals to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme.

[0006] A granulation equipment for biopharmaceuticals comprises:

[0007] A device case is provided with a support column fixedly installed on the top thereof, and a ring mill is rotatably installed on the top surface of the support column.

[0008] A receiving box is detachably installed on the outer side of the support column.

[0009] Two semicircular shells are arranged on the outer side of the ring mill, and a plurality of sieve holes are uniformly formed on the outer side of each semicircular shell.

[0010] A storage cylinder is communicatively arranged above the two semicircular shells, and the storage cylinder is fixedly connected to the device case.

[0011] The adjusting assembly is arranged outside the two semicircular cylinder shells, and comprises a U-shaped seat fixed with the storage cylinder, a gear rotating outside the U-shaped seat, two transmission rods in mesh transmission with the gear, and a screw rod capable of driving the gear to rotate and internally screwed with the U-shaped seat.

[0012] Further, a motor capable of driving the ring miller to rotate is fixed inside the equipment cabinet, and a U-shaped frame fixedly connected with the storage cylinder is fixed outside the equipment cabinet.

[0013] Further, the material receiving box comprises two symmetrically arranged splicing boxes, a semicircular cylinder block is fixed to the bottom surface of each splicing box, and a sleeve pipe is rotatably installed outside the two semicircular cylinder blocks.

[0014] Further, a connecting rod is fixed to one end of the transmission rod, a clamping groove is formed in one end of the connecting rod, and a clamping block is fixed to the top of the semicircular cylinder shell and movably inserted into the corresponding clamping groove.

[0015] Further, the adjusting assembly further comprises a U-shaped plate slidably connected with the two transmission rods.

[0016] Further, a sliding groove is formed in the outer side of the screw rod and slidably connected with the gear, and a rotating wheel is fixed to one end of the screw rod.

[0017] Further, a rotating ring is fixed to the outer side of the U-shaped seat, and a rotating groove is formed in one side of the gear and rotatably connected with the rotating ring.

[0018] Compared with the prior art, the device has the following beneficial effects:

[0019] 1. By rotating the rotating wheel, the sliding groove on the screw rod drives the gear to rotate, the gear drives the two transmission rods to mesh transmission in the direction away from each other, so that the transmission rods drive the two semicircular cylinder shells to separate and expand through the connecting rod, and the sieve holes in the two semicircular cylinder shells are exposed, which facilitates the user to clean the raw materials adhered to the inner side or outer side of the semicircular cylinder shell.

[0020] 2. By designing the traditional integrated material receiving box into two splicing boxes capable of being spliced and fixed through the sleeve pipe, when it is necessary to clean the residual raw materials in the material receiving box, the sleeve pipe can be loosened and removed, and the two splicing boxes can be removed from the supporting column, which facilitates the user to clean the raw materials adhered to the inside and outside of the material receiving box. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 is a schematic diagram of the overall structure of the device Figure 1 ;

[0022] Figure 2 is the overall structure of the present utility model Figure 2 ;

[0023] Figure 3 is the two semicircular cylinder shell of the present utility model unfolding structure diagram

[0024] Figure 4 is the adjusting assembly structure diagram of the present utility model

[0025] Figure 5 is the gear, screw, U-shaped seat split three-dimensional state structure diagram of the present utility model

[0026] Figure 6 is the receiving box structure diagram of the present utility model.

[0027] In the figure: 100, equipment machine case;110, support column;111, ring miller;120, U-shaped frame;200, receiving box;210, splicing box;211, semicircular column block;220, sleeve;300, semicircular cylinder shell;310, clamping block;400, storage cylinder;410, hopper;420, limiting ring;500, adjusting assembly;510, U-shaped seat;511, rotating ring;520, gear;530, transmission rod;540, screw;541, rotating wheel;550, connecting rod;560, U-shaped plate. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the drawings in the embodiments of the present utility model. Obviously, the described embodiments are only part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present utility model.

[0029] Embodiment one, please refer to Figure 1 - Figure 6The utility model discloses an embodiment of a granulating equipment for biological pharmacy, including equipment machine case 100, the top of equipment machine case 100 is fixed with the support column 110 of installing, the top surface of support column 110 is rotatably installed with ring miller 111, the outside of support column 110 is detachably installed with the material receiving box 200, the outside of ring miller 111 is sleeved with two semicircular cylinder shells 300, a plurality of screen holes are evenly formed in the outside of semicircular cylinder shell 300, the upper portion of two semicircular cylinder shells 300 is provided with the storage cylinder 400, the storage cylinder 400 is fixedly connected with equipment machine case 100, the outside of two semicircular cylinder shells 300 is provided with the adjusting assembly 500 capable of driving semicircular cylinder shell 300 to move, and the adjusting assembly 500 includes the U-shaped seat 510 fixed with the storage cylinder 400, the outside of U-shaped seat 510 is rotatably provided with the gear 520, the outside of gear 520 is engagedly driven with two transmission rods 530, the transmission rod 530 is fixedly installed with the corresponding position semicircular cylinder shell 300, and the inside of U-shaped seat 510 is screw-connected with the screw rod 540 capable of driving gear 520 to rotate.

[0030] Specifically, by designing the traditional integrated sieve cylinder into two semicircular cylinder shells 300 capable of being spliced with each other, when the two semicircular cylinder shells 300 are spliced to form a ring-shaped sieve cylinder, the ring miller 111 can rotate to extrude the raw materials into the screen holes of the sieve cylinder to form granular medicines, after granulation, the adjusting assembly 500 can make the two semicircular cylinder shells 300 expand in the direction away from each other, so that the inside screen holes and the outside screen holes of the semicircular cylinder shells 300 are exposed, thereby realizing that the inside screen holes and the outside screen holes of the sieve cylinder are exposed to the outside, facilitating the user to directly clean the raw materials adhered to the inside and the outside of the screen holes, and being favorable to improving the efficiency of screen hole cleaning, and meanwhile, the ring miller 111 is also exposed after the semicircular cylinder shells are removed, which is convenient for the user to clean and replace the damaged ring miller 111.

[0031] As shown in the figure, Figure 3 In the embodiment, the inside of the equipment machine case 100 is fixedly installed with a motor capable of driving the ring miller 111 to rotate, during granulation, the motor drives the ring miller 111 to rotate to extrude and deliver the raw materials to the screen hole position of the sieve cylinder composed of the two semicircular cylinder shells 300, so that the raw materials can form columnar wet granular medicines, and this part is the granulation principle of the existing rotary granulator, and the specific working principle will not be described in detail.

[0032] As shown in the figure, Figure 2 In the embodiment, the outside of the equipment machine case 100 is fixedly provided with the U-shaped frame 120 fixedly connected with the storage cylinder 400, and the U-shaped frame 120 is fixedly provided with a ring sleeved with the storage cylinder 400, so that the storage cylinder 400 is fixed at the upper position of the sieve cylinder to store the raw materials for standby granulation.

[0033] As shown in the figure, Figure 3As shown in the drawings, in the embodiment, a limiting ring 420 is fixed inside the bottom of the storage cylinder 400, so that the inner side of the two semicircular cylinder shells 300 can abut to the outer side of the limiting ring 420 when they are close to each other, and the two semicircular cylinder shells 300 are spliced into a complete sieve cylinder.

[0034] As shown in the drawings, Figure 4 As shown in the drawings, in the embodiment, one end of the transmission rod 530 is fixed with a connecting rod 550, one end of the connecting rod 550 is provided with a clamping groove, the top of the semicircular cylinder shell 300 is fixed with a clamping block 310 which is movably inserted into the corresponding clamping groove, after the transmission rod 530 drives the semicircular cylinder shell 300 to move away from the support column 110 with the connecting rod 550, the semicircular cylinder shell 300 can be moved upward, so that the clamping block 310 is separated from the clamping groove, and the semicircular cylinder shell 300 is disassembled, and vice versa, the semicircular cylinder shell 300 with different sizes of sieve holes can be installed into the clamping groove of the connecting rod 550, so that the granulating equipment can be installed with the sieve cylinder with different sizes of sieve holes, and the needs of manufacturing different sizes of medicine particles can be met.

[0035] In the embodiment, the side close to the gear 520 of the transmission rod 530 is fixed with a rack which is in meshing transmission with the gear 520, so that the rotation of the gear 520 can drive the two transmission rods 530 to move at the same time, and the outer side of the transmission rod 530 is provided with a limiting groove which is in sliding clamping with the L-shaped plate 560, so that the transmission rod 530 cannot be separated from the L-shaped plate 560 and can stably slide inside the L-shaped plate 560.

[0036] As shown in the drawings, Figure 4 and Figure 5 As shown in the drawings, in the embodiment, the outer side of the screw rod 540 is provided with a sliding groove which is in sliding clamping with the gear 520, and the inner side of the gear 520 is fixed with a sliding block which is in sliding connection with the sliding groove, when the screw rod 540 rotates, the sliding groove on the screw rod 540 drives the gear 520 to rotate through the sliding block, the rotation of the gear 520 can drive the two transmission rods 530 to move close to each other or move away from each other, so as to realize the combination of the two semicircular cylinder shells 300 into a sieve cylinder or the separation of the two semicircular cylinder shells 300 to facilitate the cleaning of the sieve hole raw materials, and in the process of rotation, the screw rod 540 will be rotated and moved in position on the L-shaped seat 510, by the characteristics of the screw rod 540 being rotated and self-locked on the L-shaped seat 510, the screw rod 540 can be kept in the position after rotation with the rotating gear 520.

[0037] In the embodiment, one end of the screw rod 540 is fixed with a rotating wheel 541, so as to facilitate the user to drive the screw rod 540 to rotate by rotating the rotating wheel 541.

[0038] As shown in the drawings, Figure 4 As shown in the drawings, in the embodiment, the outer side of the L-shaped seat 510 is fixed with a rotating ring 511, and one side of the gear 520 is provided with a rotating groove which is in rotating connection with the rotating ring 511, so that the gear 520 can stably rotate outside the L-shaped seat 510.

[0039] As shown in the figure, in the embodiment, the top of the storage cylinder 400 is communicated with a hopper 410 fixedly arranged, and the hopper 410 facilitates adding raw materials into the storage cylinder 400.

[0040] In the second embodiment, on the basis of the first embodiment, in order to facilitate cleaning the raw materials remaining in the receiving box 200.

[0041] As shown in the figures, Figure 2 and Figure 4 In the embodiment, the receiving box 200 comprises two symmetrically arranged splicing boxes 210, the bottom surface of the splicing box 210 is fixed with a semicylindrical block 211, and the outer side of the two semicylindrical blocks 211 is screw-mounted with a sleeve 220.

[0042] In the embodiment, when the receiving box 200 needs to be detached from the support column 110, the sleeve 220 is loosened reversely, so that the two semicylindrical blocks 211 are no longer bound and fixed in the sleeve 220, facilitating detaching the two splicing boxes 210 of the receiving box 200 respectively, and the rubber sleeve is fixedly sleeved at the arc-shaped gap position of the receiving box 200 close to the support column 110, and the rubber sleeve improves the firmness of the two splicing boxes 210 clamped and fixed outside the support column 110.

[0043] It is apparent for those skilled in the art that the present application is not limited to the details of the above-described exemplary embodiments, but can be implemented in other concrete forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all aspects as illustrative and not restrictive, and the scope of the present application is defined by the appended claims rather than the above description, and it is intended to encompass all changes falling within the meaning and scope of the equivalent elements of the claims. Any reference signs in the claims should not be considered as limiting the involved claims.

[0044] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the specification is described in this way only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that those skilled in the art can understand.

Claims

1. A granulating apparatus for biopharmaceuticals, characterized by comprising: The utility model relates to a device cabinet (100), the top of device cabinet (100) is installed and fixed with support column (110), the top surface of support column (110) is rotatably installed with ring miller (111); The receiving box (200) is detachably installed outside the support column (110); Two semicircular barrels (300) are arranged outside the ring miller (111), and a plurality of screen holes are uniformly formed on the outside of the semicircular barrels (300); The storage barrel (400) is arranged above the two semicircular barrels (300) in communication, and the storage barrel (400) is fixedly connected with the device cabinet (100); The adjusting assembly (500) is arranged outside the two semicircular barrels (300), and the adjusting assembly (500) comprises a U-shaped seat (510) fixedly connected with the storage barrel (400), a gear (520) rotatably arranged on the outside of the U-shaped seat (510), two transmission rods (530) rotatably connected with the gear (520), the transmission rods (530) being fixedly connected with the corresponding semicircular barrels (300), and a screw rod (540) rotatably connected in the U-shaped seat (510) and capable of driving the gear (520) to rotate. A motor capable of driving the ring miller (111) to rotate is fixedly installed in the device cabinet (100), and a U-shaped frame (120) fixedly connected with the storage barrel (400) is fixed on the outside of the device cabinet (100).

2. The biopharmaceutical granulating apparatus according to claim 1, wherein The receiving box (200) comprises two symmetrical splicing boxes (210), and a semicircular cylinder block (211) is fixedly arranged on the bottom surface of each splicing box (210); a sleeve pipe (220) is rotatably arranged on the outside of the two semicircular cylinder blocks (211).

3. The biopharmaceutical granulating apparatus according to claim 1, wherein One end of the transmission rod (530) is fixedly connected with a connecting rod (550), one end of the connecting rod (550) is provided with a clamping groove, and a clamping block (310) is fixedly arranged on the top of the semicircular barrel (300) and movably connected with the corresponding clamping groove.

4. The biopharmaceutical granulating apparatus according to claim 1, wherein The adjusting assembly (500) further comprises a U-shaped plate (560) slidably connected with the two transmission rods (530).

5. The biopharmaceutical granulating apparatus according to claim 1, wherein A sliding groove is formed on the outside of the screw rod (540) and slidably connected with the gear (520), and a rotating wheel (541) is fixedly arranged on one end of the screw rod (540).

6. The biopharmaceutical granulating apparatus according to claim 1, wherein A rotating ring (511) is fixedly arranged on the outside of the U-shaped seat (510), and a rotating groove is formed on one side of the gear (520) and rotatably connected with the rotating ring (511).

7. The biopharmaceutical granulating apparatus according to claim 1, wherein ​

Images