Recombinant collagen raw material dissolving equipment

Abstract

The utility model discloses a recombined collagen raw material dissolving equipment relates to bioengineering and chemical engineering technical field, including the dissolving box, the right side of dissolving box top end is fixedly connected with the feed inlet, the recombined collagen raw material dissolving equipment is provided with first peristaltic pump, decomposition liquid bin and second peristaltic pump, when used, the recombined collagen raw material dissolving equipment is fixed with the feed inlet through the first peristaltic pump, decomposition liquid bin and second peristaltic pump. Raw materials are put into the dissolving box through the feeding port, then dissolving liquid is put into the decomposition liquid bin from the decomposition liquid inlet, then adjusting liquid is put into the acid-alkali liquid box from the acid-alkali liquid inlet, then the volume of the put raw materials, the volume of the put dissolving liquid and the volume of the adjusting liquid are input into the first controller, and the needed solvent proportion is set; the first peristaltic pump can be controlled to automatically extract adjusting liquid from the acid-alkali liquid box, the adjusting liquid enters the decomposition liquid bin, the pH value of the dissolving liquid is adjusted, then the dissolving liquid is put into the dissolving box according to the preset proportion, finally, the motor is started, the stirring rod is driven to stir the dissolving liquid and raw materials, and the problem that the device cannot automatically and accurately conduct matching is solved.

Description

Technical Field

[0001] This utility model relates to the fields of bioengineering and chemical engineering, specifically to a device for dissolving recombinant collagen raw materials. Background Technology

[0002] Bioengineering and chemical engineering are technologies that combine biology with modern engineering technologies such as chemical machinery, making full use of the latest achievements in molecular biology to create new species with extremely distant characteristics in a short period of time. Among them, the collagen recombinant technology is commonly used in face masks and serums. The solubility of recombinant collagen directly affects its bioavailability. Well-dissolved collagen is more easily absorbed and utilized by cells, thereby exerting its biological functions. Most dissolving equipment at present still uses manual solution ratio, which has low precision, high cost, and unstable dissolving performance.

[0003] Now, a novel recombinant collagen raw material dissolving device is proposed to solve the above problems. Utility Model Content

[0004] The purpose of this invention is to provide a recombinant collagen raw material dissolving device to solve the problem of inability to automatically and accurately proportion the ingredients as mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a recombinant collagen raw material dissolving device, comprising a dissolving tank, an inlet fixedly connected to the right side of the top of the dissolving tank, a motor fixedly connected to the middle position of the top of the dissolving tank, a stirring rod fixedly connected to the bottom of the motor, and an automatic proportioning component fixedly connected to the left side of the top of the dissolving tank.

[0006] The automatic mixing assembly includes a solution tank, a first controller fixedly connected to the front end of the solution tank, an acid / alkali inlet fixedly connected to the left side of the top of the solution tank, a decomposition liquid inlet fixedly connected to the right side of the top of the solution tank, an acid / alkali tank fixedly connected to the left side inside the solution tank, a first peristaltic pump fixedly connected to the right side of the acid / alkali tank, an inlet fixedly connected to the left side of the front end of the first peristaltic pump, an outlet fixedly connected to the right side of the front end of the first peristaltic pump, a decomposition liquid chamber fixedly connected to the inside of the solution tank, and a second peristaltic pump fixedly connected to the bottom inside the solution tank, an inlet pipe fixedly connected to the left side of the front end of the second peristaltic pump, and an outlet pipe fixedly connected to the right side of the front end of the second peristaltic pump.

[0007] As a further technical solution of this utility model, the feed inlet is connected to the interior of the dissolving tank, the stirring rod is aligned with the vertical center line of the dissolving tank, and the first controller is electrically connected to the first peristaltic pump and the second peristaltic pump.

[0008] As a further technical solution of this utility model, the liquid inlet is connected to the interior of the acid and alkali liquid tank, and the liquid outlet is connected to the interior of the decomposition liquid chamber.

[0009] As a further technical solution of this utility model, the inlet pipe is connected to the interior of the decomposition liquid chamber, and the outlet pipe is connected to the interior of the dissolution tank.

[0010] As a further technical solution of this utility model, the left and right sides inside the dissolving box are fixedly connected to the tube sleeves, the left side of the front end of the dissolving box is fixedly connected to the temperature detector, the middle position of the front end of the dissolving box is fixedly connected to the second controller, and the inside of the tube sleeves is fixedly connected to the heating wire.

[0011] As a further technical solution of this utility model, the rear end of the temperature detector is connected to the interior of the melting tank, and the second controller is electrically connected to the motor.

[0012] As a further technical solution of this utility model, a filter channel is fixedly connected to the bottom of the dissolving box, a polyethersulfone 0.45-micron filter element is fixedly connected to the top of the filter channel, a polyethersulfone 0.33-micron filter element is fixedly connected to the bottom of the filter channel, an ice box is fixedly connected to the bottom of the filter channel, and ice packs are fixedly connected to the left and right sides inside the ice box.

[0013] As a further technical solution of this utility model, the filter channel is connected to the interior of the ice box, and the polyethersulfone 0.45-micron filter element is made of the same material as the polyethersulfone 0.33-micron filter element.

[0014] Compared with the prior art, the beneficial effects of this utility model are: the recombinant collagen raw material dissolving equipment not only realizes the automatic proportioning function, but also the heating function and the filtration and cooling function;

[0015] (1) By setting up a first peristaltic pump, a decomposition liquid chamber and a second peristaltic pump, when in use, the raw materials are put into the dissolving tank through the feed port, and then the dissolving liquid is put into the decomposition liquid chamber through the decomposition liquid inlet. Then the adjusting liquid is put into the acid and alkali tank through the acid and alkali inlet. Then, the volumes of the raw materials, dissolving liquid and adjusting liquid are input into the first controller, and the required solvent ratio is set. The first peristaltic pump can be controlled to automatically draw the adjusting liquid from the acid and alkali tank and enter the decomposition liquid chamber to adjust the pH value of the dissolving liquid to two to three to promote the dissolution of collagen. After adjustment, the dissolving liquid in the decomposition liquid chamber is drawn out by the second peristaltic pump. Then, according to the preset ratio, the dissolving liquid is put into the dissolving tank. Finally, the motor is started to drive the stirring rod to stir the dissolving liquid and raw materials, promote the uniform dispersion and dissolution of collagen, and realize the automatic proportioning function.

[0016] (2) By setting up a tube sleeve, a temperature detector and a heating wire, in order to promote the dissolution of collagen in the solvent, the heating wire can be turned on synchronously through the second controller to heat up the temperature. The temperature is transferred to the inside of the dissolution box through the tube sleeve. Heating can reduce the viscosity of the dissolution liquid, making it easier for collagen molecules to diffuse and disperse in the dissolution liquid. The temperature inside the dissolution box can be monitored in real time by the temperature detector and adjusted accordingly, thus realizing the heating function.

[0017] (3) By setting up a polyethersulfone 0.45 micron filter, a polyethersulfone 0.33 micron filter and an ice pack, in order to ensure the purity and quality of the dissolved collagen solution, the dissolved collagen enters the filtration channel and is first filtered by the polyethersulfone 0.45 micron filter. Then it falls into the polyethersulfone 0.33 micron filter for secondary filtration. At this time, impurities have been removed. Then it falls into the ice box and is quickly cooled and stored by the ice pack to maintain its stability and activity, thus realizing the filtration and cooling function. Attached Figure Description

[0018] Figure 1 This is a front view structural diagram of the present utility model;

[0019] Figure 2 This is an enlarged cross-sectional view of the solution tank of this utility model.

[0020] Figure 3 This is an enlarged cross-sectional view of the dissolving tank of this utility model.

[0021] Figure 4 This is an enlarged side view sectional diagram of the sleeve of this utility model.

[0022] In the diagram: 1. Dissolving tank; 2. Feed inlet; 3. Motor; 4. Stirring rod; 5. Solution tank; 6. First controller; 7. Acid / alkali solution inlet; 8. Decomposition solution inlet; 9. Acid / alkali solution tank; 10. First peristaltic pump; 11. Liquid inlet; 12. Liquid outlet; 13. Decomposition solution chamber; 14. Second peristaltic pump; 15. Liquid inlet pipe; 16. Liquid outlet pipe; 17. Tube sleeve; 18. Temperature detector; 19. Second controller; 20. Heating wire; 21. Filter channel; 22. Polyethersulfone 0.45 micron filter element; 23. Polyethersulfone 0.33 micron filter element; 24. Ice box; 25. Ice pack. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figure 1-4 An embodiment of this utility model is provided: a recombinant collagen raw material dissolving device, including a dissolving tank 1, a feed inlet 2 fixedly connected to the right side of the top of the dissolving tank 1, a motor 3 fixedly connected to the middle position of the top of the dissolving tank 1, a stirring rod 4 fixedly connected to the bottom of the motor 3, and an automatic proportioning component fixedly connected to the left side of the top of the dissolving tank 1.

[0025] Please see Figure 1-4 A recombinant collagen raw material dissolving device further includes an automatic proportioning component. The automatic proportioning component includes a solution tank 5, with a first controller 6 fixedly connected to the front end of the solution tank 5. An acid / alkali inlet 7 is fixedly connected to the left side of the top of the solution tank 5, and a decomposition liquid inlet 8 is fixedly connected to the right side of the top of the solution tank 5. An acid / alkali tank 9 is fixedly connected to the left side inside the solution tank 5, and a first peristaltic pump 10 is fixedly connected to the right side of the acid / alkali tank 9. An inlet 11 is fixedly connected to the left side of the front end of the first peristaltic pump 10, and an outlet 12 is fixedly connected to the right side of the front end of the first peristaltic pump 10. A decomposition liquid chamber 13 is fixedly connected inside the solution tank 5. The bottom of the 5 is fixedly connected to a second peristaltic pump 14. The left side of the front end of the second peristaltic pump 14 is fixedly connected to an inlet pipe 15, and the right side of the front end of the second peristaltic pump 14 is fixedly connected to an outlet pipe 16. The feed inlet 2 is connected to the inside of the dissolving tank 1. The stirring rod 4 is aligned with the vertical center line of the dissolving tank 1. The first controller 6 is electrically connected to the first peristaltic pump 10 and the second peristaltic pump 14. The inlet 11 is connected to the inside of the acid-base solution tank 9. The outlet 12 is connected to the inside of the decomposition liquid chamber 13. The inlet pipe 15 is connected to the inside of the decomposition liquid chamber 13. The outlet pipe 16 is connected to the inside of the dissolving tank 1. Automatic proportioning and precise dispensing are achieved.

[0026] Specifically, such as Figure 1 , Figure 2 and Figure 3As shown, in use, the raw materials are fed into the dissolving tank 1 through the feed inlet 2. Then, the dissolving solution is fed into the decomposition liquid chamber 13 through the decomposition liquid inlet 8. Next, the adjusting solution is fed into the acid-alkali solution tank 9 through the acid-alkali solution inlet 7. Then, the volumes of the raw materials, dissolving solution, and adjusting solution are input into the first controller 6, and the required solvent ratio is set. The first peristaltic pump 10 can then be controlled to automatically draw the adjusting solution from the acid-alkali solution tank 9 and enter the decomposition liquid chamber 13 to adjust the pH value of the dissolving solution to two to three to promote the dissolution of collagen. After adjustment, the dissolving solution in the decomposition liquid chamber 13 is drawn out by the second peristaltic pump 14 and then added into the dissolving tank 1 according to the preset ratio. Finally, the motor 3 is started to drive the stirring rod 4 to stir the dissolving solution and raw materials, promoting the uniform dispersion and dissolution of collagen. The automatic proportioning is accurate and saves manpower.

[0027] Tube sleeves 17 are fixedly connected to the left and right sides inside the dissolving box 1. A temperature detector 18 is fixedly connected to the left side of the front end of the dissolving box 1. A second controller 19 is fixedly connected to the middle position of the front end of the dissolving box 1. A heating wire 20 is fixedly connected inside the tube sleeves 17. The rear end of the temperature detector 18 is connected to the inside of the dissolving box 1. The second controller 19 is electrically connected to the motor 3. Heating promotes the movement of internal molecules.

[0028] Specifically, such as Figure 3 and Figure 4 As shown, in order to promote the dissolution of collagen in the solvent, the heating wire 20 can be turned on synchronously by the second controller 19 to heat up the temperature. The temperature is transferred to the interior of the dissolution box 1 through the sleeve 17. Heating can reduce the viscosity of the solution, making it easier for collagen molecules to diffuse and disperse in the solution. The temperature inside the dissolution box 1 can be monitored and adjusted in real time by the temperature detector 18 to accelerate dispersion and diffusion.

[0029] A filter channel 21 is fixedly connected to the bottom of the dissolving chamber 1. A polyethersulfone 0.45-micron filter element 22 is fixedly connected to the top of the filter channel 21. A polyethersulfone 0.33-micron filter element 23 is fixedly connected to the bottom of the filter channel 21. An ice box 24 is fixedly connected to the bottom of the filter channel 21. Ice packs 25 are fixedly connected to the left and right sides of the ice box 24. The filter channel 21 and the ice box 24 are connected. The polyethersulfone 0.45-micron filter element 22 and the polyethersulfone 0.33-micron filter element 23 are made of the same material and screen out large molecular particles inside.

[0030] Specifically, such as Figure 1 and Figure 3As shown, in order to ensure the purity and quality of the dissolved collagen solution, the dissolved collagen enters the filter channel 21 and is first filtered by the polyethersulfone 0.45-micron filter element 22. Then it falls into the polyethersulfone 0.33-micron filter element 23 for secondary filtration. At this time, impurities have been removed. Then it falls into the ice box 24 and is rapidly cooled and stored by the ice pack 25 to maintain its stability, activity and purity.

[0031] Working Principle: In use, the raw materials are first fed into the dissolving tank 1 through the feed inlet 2. Then, the dissolving solution is fed into the decomposition liquid chamber 13 through the decomposition liquid inlet 8. Next, the adjusting solution is fed into the acid / alkali tank 9 through the acid / alkali inlet 7. The volumes of the raw materials, dissolving solution, and adjusting solution are input into the first controller 6, and the desired solvent ratio is set. The first peristaltic pump 10 then automatically draws the adjusting solution from the acid / alkali tank 9 into the decomposition liquid chamber 13 to adjust the pH of the dissolving solution to between two and three, promoting collagen dissolution. After adjustment, the second peristaltic pump 14 draws the dissolving solution from the decomposition liquid chamber 13 and, according to the preset ratio, adds it into the dissolving tank 1. Finally, the motor 3 is started, driving the stirring rod 4 to stir the dissolving solution and raw materials, promoting uniform dispersion of collagen. During use, to promote the dissolution of collagen in the solvent, the heating wire 20 can be turned on synchronously via the second controller 19 to raise the temperature. The temperature is transferred to the interior of the dissolution chamber 1 through the sleeve 17. Heating can reduce the viscosity of the solution, making it easier for collagen molecules to diffuse and disperse in the solution. The internal temperature of the dissolution chamber 1 can be monitored and adjusted in real time via the temperature detector 18. During use, to ensure the purity and quality of the dissolved collagen solution, the dissolved collagen enters the filtration channel 21 and is first filtered by the polyethersulfone 0.45-micron filter element 22. Then it falls into the polyethersulfone 0.33-micron filter element 23 for secondary filtration. At this time, impurities have been removed. Then it falls into the ice box 24 and is rapidly cooled and stored by the ice pack 25 to maintain its stability and activity.

[0032] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A reconstituted collagen raw material dissolving apparatus comprising a dissolving tank (1), characterized in that: The right side of the top end of the dissolving box (1) is fixedly connected with a feeding port (2), the middle position of the top end of the dissolving box (1) is fixedly connected with a motor (3), the bottom of the motor (3) is fixedly connected with a stirring rod (4), and the left side of the top end of the dissolving box (1) is fixedly connected with an automatic proportioning assembly. The automatic proportioning assembly comprises a solution tank (5), the front end of the solution tank (5) is fixedly connected with a first controller (6), the left side of the top end of the solution tank (5) is fixedly connected with an acid-alkali liquid inlet (7), the right side of the top end of the solution tank (5) is fixedly connected with a decomposition liquid inlet (8), the left side in the inside of the solution tank (5) is fixedly connected with an acid-alkali liquid tank (9), the right side of the acid-alkali liquid tank (9) is fixedly connected with a first peristaltic pump (10), the left side of the front end of the first peristaltic pump (10) is fixedly connected with a liquid inlet (11), the right side of the front end of the first peristaltic pump (10) is fixedly connected with a liquid outlet (12), the inside of the solution tank (5) is fixedly connected with a decomposition liquid bin (13), the bottom end in the inside of the solution tank (5) is fixedly connected with a second peristaltic pump (14), the left side of the front end of the second peristaltic pump (14) is fixedly connected with a liquid inlet pipe (15), and the right side of the front end of the second peristaltic pump (14) is fixedly connected with a liquid outlet pipe (16).

2. The reconstituted collagen raw material dissolving apparatus according to claim 1, characterized by: The feeding port (2) is communicated with the inside of the dissolving box (1), the stirring rod (4) is consistent with the vertical center line of the dissolving box (1), and the first controller (6) is electrically connected with the first peristaltic pump (10) and the second peristaltic pump (14).

3. The reconstituted collagen raw material dissolving apparatus according to claim 1, characterized by: The liquid inlet (11) is communicated with the inside of the acid-alkali liquid tank (9), and the liquid outlet (12) is communicated with the inside of the decomposition liquid bin (13).

4. The reconstituted collagen raw material dissolving apparatus according to claim 1, characterized by: The liquid inlet pipe (15) is communicated with the inside of the decomposition liquid bin (13), and the liquid outlet pipe (16) is communicated with the inside of the dissolving box (1).

5. The reconstituted collagen raw material dissolving apparatus according to claim 1, characterized by: The left and right sides in the inside of the dissolving box (1) are fixedly connected with pipe sleeves (17), the left side of the front end of the dissolving box (1) is fixedly connected with a temperature detector (18), the middle position of the front end of the dissolving box (1) is fixedly connected with a second controller (19), and the inside of the pipe sleeve (17) is fixedly connected with an electric heating wire (20).

6. The reconstituted collagen raw material dissolving apparatus according to claim 5, characterized by: The rear end of the temperature detector (18) is connected with the inside of the dissolving box (1), and the second controller (19) is electrically connected with the motor (3).

7. The reconstituted collagen raw material dissolving apparatus according to claim 1, characterized by: The bottom end of the dissolving box (1) is fixedly connected with a filtering channel (21), the top end in the inside of the filtering channel (21) is fixedly connected with a polyether sulfone 0.45-micron filter core (22), the bottom end in the inside of the filtering channel (21) is fixedly connected with a polyether sulfone 0.33-micron filter core (23), the bottom end of the filtering channel (21) is fixedly connected with an ice box (24), and the left and right sides in the inside of the ice box (24) are fixedly connected with ice bags (25).

8. The reconstituted collagen raw material dissolving apparatus according to claim 7, characterized by: The filtering channel (21) is communicated with the inside of the ice box (24), and the polyether sulfone 0.45-micron filter core (22) is made of the same material as the polyether sulfone 0.33-micron filter core (23).

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