Protein ultrafiltration equipment
By utilizing the annular cavity structure of the ultrafiltration tube and outer tube body, along with the design of a movable valve block in the protein ultrafiltration equipment, the problem of high energy consumption during protein purification has been solved, achieving efficient and low-cost protein solution purification.
Patent Information
- Application Number
- CN202520361930.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-03
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2035-03-03
AI Technical Summary
Current protein purification processes consume a lot of energy, especially inefficient processes involving repeated sedimentation and tubular centrifugation.
The protein ultrafiltration equipment uses an annular cavity between the ultrafiltration tube and the outer tube to filter the solution. It utilizes pressure difference and gravity to split and discharge the solution, and combines a movable valve block structure for cleaning, thereby improving the processing speed and efficiency of the equipment.
It reduces energy consumption, increases the speed and efficiency of the protein purification process, and lowers the operating costs of the equipment.
Smart Images
Figure CN223800338U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the equipment technical field of protein ultrafiltration, specifically to a kind of equipment for protein ultrafiltration. BACKGROUND
[0002] Hydrolyzed protein is a compound biochemical medicine obtained by enzyme hydrolysis reaction of animal and plant protein, and its main components are various amino acids, short peptides and various trace elements required by human body, which is used for low proteinemia and malnutrition caused by various diseases, whole body failure, and can also be used for burn, fracture and poor wound healing after operation.
[0003] Hydrolyzed protein extract needs to be filtered, concentrated and purified to obtain clear concentrated solution, and then made into oral liquid or oral powder. Through repeated circulation operation of 4-5 times by sedimentation+pipe type centrifugation, protein solution is purified, so that energy consumption is large. UTILITY MODEL CONTENT
[0004] The purpose of the present application is to provide a protein ultrafiltration equipment to solve the problem of large consumption of existing protein purification.
[0005] To solve the above technical problems, the utility model is realized by the following technical scheme:
[0006] The utility model relates to a kind of equipment for protein ultrafiltration, including filter piece, the filter piece includes outer tube body and ultrafiltration tube, the inside of outer tube body is equipped with ultrafiltration tube, the both ends of outer tube body are connected with sleeve, the sleeve is matched with the installation of plug, annular cavity is formed between outer tube body and ultrafiltration tube;
[0007] Wherein, the sleeve is equipped with second pipe orifice, and the plug is equipped with first pipe orifice;
[0008] The second pipe orifice is communicated with annular cavity, and the first pipe orifice is communicated with the inside of ultrafiltration tube.
[0009] The solution containing protein needing to be ultrafiltrated passes through the inside of ultrafiltration tube, and the moisture in the solution containing protein is filtered into the annular cavity formed between outer tube body and ultrafiltration tube by pressure difference, and is discharged through the interface of annular cavity formed between outer tube body and ultrafiltration tube, to complete the purification work of the solution containing protein.
[0010] Further, the filter piece is provided with a plurality of filter pieces, and the plurality of filter pieces are divided into two rows, and the filter pieces distributed in rows are installed on the mounting bracket, and the mounting bracket is installed on the inner side of the frame.
[0011] By being provided with multiple filter pieces, the processing speed of the whole equipment can be improved.
[0012] Further, the filter is vertically distributed, the second pipe orifice on the upper side is communicated with the first pipe line, and the second pipe orifice on the lower side is communicated with the second pipe line;
[0013] The first pipe line, the annular cavity and the second pipe line constitute a first passage.
[0014] The first pipe orifice on the upper side is communicated with the collecting pipe, and the first pipe orifice on the lower side is communicated with the distributing pipe.
[0015] The collecting pipe, the ultrafiltration pipe and the distributing pipe constitute a second passage.
[0016] The solution containing protein to be purified enters the inside of the ultrafiltration pipe through the distributing pipe and is discharged through the collecting pipe, and the solution containing protein flows upward, and the pressure of the solution containing protein is increased to promote the upward flow;
[0017] The water passing through the ultrafiltration pipe enters the inside of the ultrafiltration pipe and flows downward under the action of gravity to be discharged through the second pipe line, and the excessive water passing through is overflowed through the first pipe line.
[0018] Further, the same side of the first pipe line and the second pipe line is connected through a valve body.
[0019] Further, the valve body comprises a connecting pipe, and the two ends of the connecting pipe are communicated with the first pipe line and the second pipe line respectively.
[0020] A guide rod is installed in the connecting pipe, the two ends of the guide rod extend out of the connecting pipe, a valve block is installed on the guide rod, the valve block is located in the inside of the connecting pipe, the top end of the guide rod is connected with a telescopic rod, and the telescopic rod is installed at the end of the connecting pipe.
[0021] The outer side of the connecting pipe is connected with a connecting port.
[0022] When the ultrafiltration pipe is cleaned, the valve installed at the drainage end of the first pipe line and the second pipe line is closed, the guide rod is pushed by the telescopic rod to drive the valve block to move upward, the connecting port on the lower side of the connecting pipe is communicated, the water flow enters the inside of the first pipe line through the connecting pipe, the water passing through the inner wall of the ultrafiltration pipe enters the annular cavity between the outer pipe body and the ultrafiltration pipe, and is discharged through the distributing pipe to realize the reverse cleaning of the ultrafiltration pipe.
[0023] When the cleaning is completed, the guide rod is pushed by the telescopic rod to drive the valve block to move downward to realize the closure of the port of the connecting port.
[0024] The cross section of the guide rod is elliptical to avoid rotation of the guide rod during movement.
[0025] The connecting ports provided on the connecting pipes are located on the same side, and the valve block closes one communication of the connecting port and the connecting pipe.
[0026] The valve block is semicylindrical, and the arc surface of the valve block faces the side of the connecting port.
[0027] The utility model has the following beneficial effects:
[0028] (1) the solution containing protein which needs to be purified of the utility model enters the inside of the ultrafiltration pipe through the liquid separation pipe, and is discharged through the liquid collecting pipe, and the filtration is realized through the pressure difference, and compared with the static and centrifugal, the time consumption is short and the energy consumption is small, the solution containing protein flows upwards, the pressure of the solution containing protein is increased, so that the upward flow is promoted, the water passing through the ultrafiltration pipe enters the inside of the ultrafiltration pipe, and flows downwards under the action of gravity, so that the discharge through the second pipeline is realized, and the water passing through is too much, and the water flow overflows through the first pipeline.
[0029] (2) the valve installed at the drainage end of the first pipeline and the second pipeline is closed, the valve block is driven to move upwards through the telescopic rod and the guide rod, the connecting port on the lower side of the connecting pipe is communicated, the water flow enters the inside of the first pipeline through the connecting pipe, the inner wall of the ultrafiltration pipe enters the annular cavity formed between the outer pipe body and the ultrafiltration pipe, and is discharged through the liquid separation pipe, so that the reverse cleaning of the ultrafiltration pipe is realized.
[0030] Of course, any product implementing the utility model does not necessarily need to achieve all the advantages described above. BRIEF DESCRIPTION OF DRAWINGS
[0031] In order to more clearly illustrate the technical scheme of the embodiments of the utility model, the following will briefly introduce the drawings needed to be used in the embodiment description, and obviously, the drawings in the following description are only some embodiments of the utility model, and for those skilled in the art, other drawings can also be obtained according to these drawings without creating labor.
[0032] Figure 1 It is the overall schematic diagram of the utility model;
[0033] Figure 2 It is the internal schematic diagram of the utility model;
[0034] Figure 3 It is the local schematic diagram of the utility model;
[0035] Figure 4 It is the schematic diagram of the filter element of the utility model;
[0036] Figure 5 It is the sectional schematic diagram of the filter element of the utility model;
[0037] Figure 6 It is a valve body schematic view of the utility model;
[0038] Figure 7 It is a valve body exploded schematic view of the utility model;
[0039] In the drawing, the component list represented by each sign is as follows:
[0040] In the drawing: 1, frame; 2, mounting frame; 3, filter piece; 31, outer pipe body; 32, sleeve; 321, second pipe orifice; 33, plug; 331, first pipe orifice; 34, ultrafiltration pipe; 4, liquid collecting pipe; 5, first pipeline; 6, second pipeline; 7, liquid distribution pipe; 8, valve body; 81, connecting pipe; 811, connecting orifice; 82, guide rod; 83, valve block; 84, telescopic rod. DETAILED DESCRIPTION
[0041] The technical scheme in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.
[0042] Please refer to Figures 1-7 The utility model discloses a kind of equipment for protein ultrafiltration, including filter piece 3, filter piece 3 includes outer pipe body 31 and ultrafiltration pipe 34, the inside of outer pipe body 31 is equipped with ultrafiltration pipe 34, the both ends of outer pipe body 31 are connected with sleeve 32, sleeve 32 is cooperatively installed with plug 33, annular cavity is formed between outer pipe body 31 and ultrafiltration pipe 34;
[0043] Ultrafiltration pipe 34 includes pipe orifice, ultrafiltration membrane and filter membrane support structure, pipe orifice is equipped with two, two pipe orifices are installed with filter membrane support structure, the outside of filter membrane support structure is installed with ultrafiltration membrane, and constitutes pipe body structure.
[0044] Among them, sleeve 32 is equipped with second pipe orifice 321, plug 33 is equipped with first pipe orifice 331.
[0045] Second pipe orifice 321 is communicated with annular cavity, and first pipe orifice 331 is communicated with the inside of ultrafiltration pipe 34.
[0046] The solution containing protein needing to be ultrafiltrated, through the inside of ultrafiltration pipe 34, by pressure difference, the moisture in the solution containing protein is filtered into the annular cavity formed between outer pipe body 31 and ultrafiltration pipe 34, is discharged through the interface of the annular cavity formed between outer pipe body 31 and ultrafiltration pipe 34, and the solution containing protein is purified.
[0047] The filter 3 is provided with a plurality of filter 3, a plurality of filter 3 is divided into two rows, the row distribution filter 3 is installed on the mounting frame 2, the mounting frame 2 is installed on the inner side of the frame 1;
[0048] By being provided with a plurality of filter 3, thereby can improve the processing speed of the whole equipment.
[0049] The filter 3 is vertically distributed, the second pipe 321 on the upper side is communicated with the first pipe 5, and the second pipe 321 on the lower side is communicated with the second pipe 6;
[0050] Among them, the first pipe 5, the annular cavity and the second pipe 6 constitute a first passage;
[0051] The first pipe 331 on the upper side is communicated with the liquid collecting pipe 4, and the first pipe 331 on the lower side is communicated with the distribution pipe 7;
[0052] Among them, the liquid collecting pipe 4, the ultrafiltration pipe 34 and the distribution pipe 7 constitute a second passage.
[0053] The solution containing protein which needs to be purified enters the inside of the ultrafiltration pipe 34 through the distribution pipe 7, and is discharged through the liquid collecting pipe 4, the solution containing protein flows upward, the pressure of the solution containing protein is increased, so as to promote the upward flow;
[0054] The water passing through the ultrafiltration pipe 34 enters the inside of the ultrafiltration pipe 34, and flows downward under the action of gravity, so as to be discharged through the second pipe 6, the water passing through is too much, and the water flow overflows through the first pipe 5.
[0055] The same side of the first pipe 5 and the second pipe 6 is connected through the valve body 8.
[0056] The valve body 8 includes a connecting pipe 81, both ends of the connecting pipe 81 are communicated with the first pipe 5 and the second pipe 6 respectively;
[0057] A guide rod 82 is installed in the connecting pipe 81, both ends of the guide rod 82 extend out of the connecting pipe 81, a valve block 83 is installed on the guide rod 82, the valve block 83 is located in the inside of the connecting pipe 81, the top end of the guide rod 82 is connected with a telescopic rod 84, and the telescopic rod 84 is installed at the end of the connecting pipe 81;
[0058] The outer side of the connecting pipe 81 is connected with a connecting port 811.
[0059] When the ultrafiltration tube 34 is cleaned, the valves installed at the water outlet ends of the first pipeline 5 and the second pipeline 6 are closed, the valve block 83 is driven to move upward by the guide rod 82 pushed by the telescopic rod 84, the connection port 811 at the lower side of the connecting pipe 81 is communicated, water flows into the first pipeline 5 through the connecting pipe 81, passes through the inner wall of the ultrafiltration tube 34 into the annular cavity formed between the outer tube body 31 and the ultrafiltration tube 34, and is discharged through the distribution pipe 7, so that the ultrafiltration tube 34 is reversely cleaned.
[0060] When the cleaning is completed, the valve block 83 is driven to move downward by the guide rod 82 pushed by the telescopic rod 84, so that the port of the connection port 811 is closed.
[0061] The cross section of the guide rod 82 is oval, so that the guide rod 82 is prevented from rotating during movement.
[0062] The connection ports provided on the connecting pipe 81 are located at the same side, and the valve block 83 closes one communication position between the connection port and the connecting pipe 81.
[0063] The valve block 83 is semicylindrical, and the arc surface of the valve block 83 faces one side of the connection port 811.
[0064] The preferred embodiments disclosed above are only used for helping to describe the utility model. The preferred embodiments do not describe all the details, and do not limit the utility model to the specific embodiments. Apparently, according to the content of the specification, many modifications and changes can be made. The specification selects and specifically describes these embodiments, so as to better explain the principle and practical application of the utility model, so that the persons skilled in the art can well understand and utilize the utility model. The utility model is limited by the claims and the whole scope and equivalents thereof.
Claims
1. A device for protein ultrafiltration, comprising a filter element (3), characterized in that: the filter element (3) comprises an outer tube body (31) and an ultrafiltration tube (34); the inner part of the outer tube body (31) is provided with the ultrafiltration tube (34), both ends of the outer tube body (31) are connected with a sleeve (32), and a plug (33) is fitted and installed in the sleeve (32); an annular cavity is formed between the outer tube body (31) and the ultrafiltration tube (34); wherein the sleeve (32) is provided with a second pipe opening (321), and the plug (33) is provided with a first pipe opening (331); the second pipe opening (321) is in communication with the annular cavity, and the first pipe opening (331) is in communication with the inside of the ultrafiltration tube (34). A plurality of filter elements (3) are provided, and the plurality of filter elements (3) are divided into two rows. The filter elements (3) are vertically distributed. The second pipe opening (321) on the upper side is in communication with a first pipe line (5). The second pipe opening (321) on the lower side is in communication with a second pipe line (6). The first pipe line (5), the annular cavity, and the second pipe line (6) constitute a first passage.
2. The apparatus for protein ultrafiltration according to claim 1, characterized in that: The first pipe opening (331) on the upper side is in communication with a liquid collecting pipe (4).
3. The apparatus for protein ultrafiltration according to claim 1, characterized in that: The first pipe opening (331) on the lower side is in communication with a liquid distributing pipe (7). The liquid collecting pipe (4), the ultrafiltration tube (34), and the liquid distributing pipe (7) constitute a second passage. The same side of the first pipe line (5) and the second pipe line (6) is connected through a valve body (8). The valve body (8) comprises a connecting pipe (81), both ends of the connecting pipe (81) are in communication with the first pipe line (5) and the second pipe line (6) respectively; A guide rod (82) is installed in the connecting pipe (81), both ends of the guide rod (82) extend out of the connecting pipe (81), a valve block (83) is installed on the guide rod (82), the valve block (83) is located in the inside of the connecting pipe (81), the top end of the guide rod (82) is connected with a telescopic rod (84), and the telescopic rod (84) is installed at the end of the connecting pipe (81); The outer side of the connecting pipe (81) is connected with a connecting opening (811). The cross section of the guide rod (82) is oval; 4. The apparatus for protein ultrafiltration according to claim 3, wherein: The connecting openings provided on the connecting pipe (81) are located on the same side, and the valve block (83) closes one communication between the connecting opening and the connecting pipe (81).
5. The apparatus for protein ultrafiltration according to claim 4, characterized in that: The filter elements (3) distributed in rows are installed on a mounting rack (2), and the mounting rack (2) is installed on the inner side of a frame (1). 6. The apparatus for protein ultrafiltration according to claim 5, characterized in that: 7. The apparatus for protein ultrafiltration according to claim 1, characterized in that: