Thermal suction filtration treatment device for trifluoromethylpyridine medical intermediates

Abstract

The utility model relates to the technical field of filtering devices, in particular to a trifluoromethylpyridine medical intermediate thermal suction filtration treatment device which comprises a heating cylinder, a filtering assembly is arranged in the heating cylinder and comprises a sealing ring, a filtering membrane, a funnel, a sliding rod, a sliding groove and a spring, the sealing ring is connected to the inner wall of the heating cylinder in a sliding mode, and the filtering membrane is arranged on the funnel. The filter membrane is arranged on the sealing ring, the funnel is fixedly connected to the bottom of the sealing ring, the sliding groove is formed in the inner wall of the heating cylinder, the sliding rod is fixedly connected to the sealing ring, the sliding rod is slidably connected into the sliding groove, and the spring is fixedly connected between the sliding rod and the inner wall of the sliding groove. A pressurizing assembly is further arranged in the heating cylinder. In the whole filtering process, the piston can be used for pressurizing, and the heating cylinder can be used for heating, so that the filtering effect can be improved, and trifluoromethylpyridine compounds can be prevented from separating out crystals and being intercepted by the filter membrane.

Description

Technical Field

[0001] This utility model relates to the field of filtration device technology, specifically a thermal filtration device for trifluoromethylpyridine pharmaceutical intermediates. Background Technology

[0002] Trifluoromethylpyridine compounds are a class of six-membered heterocyclic compounds with high biological activity and structural diversity, and are widely used in the pharmaceutical field as pharmaceutical intermediates.

[0003] The production of trifluoromethylpyridine compounds involves filtration processes. However, due to the high density of the liquid and the precipitation of varying amounts of crystals under different temperature conditions, conventional filtration devices are ineffective during filtration. Therefore, a new type of filtration device is needed to solve this problem. Utility Model Content

[0004] To address the aforementioned technical problems, this invention proposes a thermal filtration device for trifluoromethylpyridine pharmaceutical intermediates, which can heat and pressurize the solution during the filtration process, thereby improving the filtration effect.

[0005] The technical solution to achieve the purpose of this utility model is as follows: a thermal filtration treatment device for trifluoromethylpyridine pharmaceutical intermediates, including a heating cylinder, a filter assembly inside the heating cylinder, the filter assembly including a sealing ring, a filter membrane, a funnel, a slide rod, a slide groove and a spring, the sealing ring being slidably connected to the inner wall of the heating cylinder, the filter membrane being disposed on the sealing ring, the funnel being fixedly connected to the bottom of the sealing ring, the slide groove being formed on the inner wall of the heating cylinder, the slide rod being fixedly connected to the sealing ring and slidably connected to the inside of the slide groove, the spring being fixedly connected between the slide rod and the inner wall of the slide groove, and a pressure assembly being provided inside the heating cylinder.

[0006] Preferably, the pressurizing assembly includes a piston and a screw, the piston being slidably connected to the inside of the heating cylinder, and one end of the screw being rotatably connected to the piston.

[0007] Preferably, the pressurizing assembly further includes a bracket, insert rods, and slots. The bracket is threaded onto a screw, the two insert rods are fixedly connected to both ends of the bracket, the two slots are formed on the heating cylinder, and the two insert rods are slidably connected to the interior of the two slots.

[0008] Preferably, the pressurizing assembly further includes a connecting block and a swing arm. The two connecting blocks are respectively disposed on the bracket and the piston. One connecting block is fixedly connected to the bracket, and the other connecting block is slidably connected to the piston. The two ends of the swing arm are rotatably connected to the two connecting blocks respectively.

[0009] Preferably, the pressurizing assembly further includes a connecting ring, which is fixedly connected to the sealing ring and slidably connected to the inner wall of the heating cylinder.

[0010] Compared with the prior art, the significant advantages of this utility model are:

[0011] Firstly, in this invention, the trifluoromethylpyridine compound solution to be filtered is poured into a heating cylinder. The heating cylinder can be plugged in and its walls can be heated, thereby heating the trifluoromethylpyridine compound and increasing its solubility, thus preventing the trifluoromethylpyridine compound from precipitating crystals during the filtration process.

[0012] Secondly, in this invention, during filtration, two rods can be inserted into two slots respectively to fix the support. Then, the screw is rotated. When the screw rotates, it will drive the piston to move downward. When the piston moves downward, it will squeeze the trifluoromethylpyridine compound solution below. The effect of suction filtration is achieved by pressurization, so that the denser trifluoromethylpyridine compound solution can pass through the filter membrane. The trifluoromethylpyridine compound solution that passes through the filter membrane will be discharged from the funnel. The filtered trifluoromethylpyridine compound solution can be collected by placing a container under the heating cylinder in advance. Attached Figure Description

[0013] The present invention will be further explained below with reference to the accompanying drawings and embodiments:

[0014] Figure 1 This is a three-dimensional structural schematic diagram of the present invention;

[0015] Figure 2 This is a three-dimensional structural diagram of the pressurizing component in this utility model;

[0016] Figure 3 This is a cross-sectional view of the internal structure of this utility model;

[0017] Figure 4 This is an exploded view of the filter component in this utility model.

[0018] Explanation of reference numerals in the attached figures:

[0019] 1. Heating cylinder; 2. Filter assembly; 21. Sealing ring; 22. Filter membrane; 23. Funnel; 24. Sliding rod; 25. Slide groove; 26. Spring; 3. Pressurizing assembly; 31. Piston; 32. Connecting ring; 33. Bracket; 34. Insert rod; 35. Slot; 36. Screw; 37. Connecting block; 38. Swing rod. Detailed Implementation

[0020] The present invention will now be described in detail, and the technical solutions in the embodiments of the present invention will be clearly and completely described. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present invention.

[0021] This utility model provides an improved thermal filtration treatment device for trifluoromethylpyridine pharmaceutical intermediates. The technical solution of this utility model is as follows:

[0022] like Figures 1-4 As shown, a thermal filtration device for trifluoromethylpyridine pharmaceutical intermediates includes a heating cylinder 1. A filter assembly 2 is installed inside the heating cylinder 1. The filter assembly 2 includes a sealing ring 21, a filter membrane 22, a funnel 23, a sliding rod 24, a sliding groove 25, and a spring 26. The sealing ring 21 is slidably connected to the inner wall of the heating cylinder 1. The filter membrane 22 is disposed on the sealing ring 21. The funnel 23 is fixedly connected to the bottom of the sealing ring 21. The sliding groove 25 is formed on the inner wall of the heating cylinder 1. The sliding rod 24 is fixedly connected to the sealing ring 21 and slidably connected inside the sliding groove 25. The spring 26 is fixedly connected between the sliding rod 24 and the inner wall of the sliding groove 25. A pressure assembly 3 is also installed inside the heating cylinder 1.

[0023] Furthermore, the pressurizing component 3 includes a piston 31 and a screw 36. The piston 31 is slidably connected to the inside of the heating cylinder 1, and one end of the screw 36 is rotatably connected to the piston 31. The screw 36 can be manually rotated, which causes the piston 31 to move downward. The trifluoromethylpyridine compound solution has a high density and is difficult to pass through the filter membrane 22 by its own gravity. However, the downward movement of the piston 31 can generate pressure, allowing the high-density trifluoromethylpyridine compound solution to pass through the filter membrane 22.

[0024] Furthermore, the pressurizing assembly 3 also includes a bracket 33, insert rods 34, and slots 35. The bracket 33 is threaded onto the screw 36. The two insert rods 34 are fixedly connected to both ends of the bracket 33. The two slots 35 are opened on the heating cylinder 1. The two insert rods 34 are slidably connected to the inside of the two slots 35. The bracket 33 can be fixed by inserting the insert rods 34 into the slots 35, which facilitates the rotation of the screw 36.

[0025] Furthermore, the pressurizing assembly 3 also includes a connecting block 37 and a rocker arm 38. The two connecting blocks 37 are respectively disposed on the bracket 33 and the piston 31. One connecting block 37 is fixedly connected to the bracket 33, and the other connecting block 37 is slidably connected to the piston 31. The two ends of the rocker arm 38 are rotatably connected to the two connecting blocks 37 respectively. When the piston 31 moves down, the connecting block 37 located on the piston 31 will slide, and swing along with the rocker arm 38, so that the piston 31 can move in the vertical direction.

[0026] Furthermore, the pressurizing assembly 3 also includes a connecting ring 32, which is fixedly connected to the sealing ring 21 and slidably connected to the inner wall of the heating cylinder 1. The inner wall of the connecting ring 32 is beveled, and the bottom of the piston 31 can fit against the connecting ring 32. When the trifluoromethylpyridine compound solution is about to be completely filtered, the piston 31 will fit against the connecting ring 32 so that the solution can be more easily squeezed onto the filter membrane 22.

[0027] The specific working method is as follows: The trifluoromethylpyridine compound solution to be filtered is poured into heating cylinder 1. Heating cylinder 1 is electrically powered, and its walls can be heated, thus increasing the solubility of the trifluoromethylpyridine compound and preventing crystal precipitation during filtration. During filtration, two rods 34 are inserted into two slots 35 to fix the support 33. Then, the screw 36 is rotated. As the screw 36 rotates, it moves the piston 31 downwards, compressing the trifluoromethylpyridine compound solution below. This pressure-based filtration achieves the effect of suction, allowing the denser trifluoromethylpyridine compound solution to be filtered. The trifluoromethylpyridine compound solution passing through the filter membrane 22 will be discharged from the funnel 23. A container placed below the heating cylinder 1 in advance can be used to collect the filtered trifluoromethylpyridine compound solution. Since the piston 31 can be pressurized and the heating cylinder 1 can be heated during the entire filtration process, not only can the filtration effect be improved, but also the crystal precipitation of trifluoromethylpyridine compounds can be avoided and intercepted by the filter membrane 22. If the pressure is too high during the downward movement of the piston 31, the filter membrane 22 can move downward with the sealing ring 21 and move downward in the slide groove 25 along with the slide rod 24, squeezing the spring 26. After the filtration process is completed, the spring 26 can reset the sealing ring 21 and the filter membrane 22.

[0028] The technical means disclosed in this utility model are not limited to those described above, but also include technical solutions composed of equivalent substitutions of the above technical features. Matters not covered in this utility model are common knowledge to those skilled in the art.

Claims

1. A thermal filtration apparatus for trifluoromethylpyridine pharmaceutical intermediates, comprising a heating cylinder (1), characterized in that: The heating cylinder (1) is equipped with a filter assembly (2), which includes a sealing ring (21), a filter membrane (22), a funnel (23), a slide rod (24), a groove (25), and a spring (26). The sealing ring (21) is slidably connected to the inner wall of the heating cylinder (1), the filter membrane (22) is disposed on the sealing ring (21), the funnel (23) is fixedly connected to the bottom of the sealing ring (21), the groove (25) is opened on the inner wall of the heating cylinder (1), the slide rod (24) is fixedly connected to the sealing ring (21), and the slide rod (24) is slidably connected to the inside of the groove (25). The spring (26) is fixedly connected between the slide rod (24) and the inner wall of the groove (25). The heating cylinder (1) is also equipped with a pressurizing assembly (3).

2. The thermal filtration treatment apparatus for trifluoromethylpyridine pharmaceutical intermediates according to claim 1, characterized in that: The pressurizing assembly (3) includes a piston (31) and a screw (36). The piston (31) is slidably connected to the inside of the heating cylinder (1), and one end of the screw (36) is rotatably connected to the piston (31).

3. The thermal filtration treatment apparatus for trifluoromethylpyridine pharmaceutical intermediates according to claim 2, characterized in that: The pressurizing assembly (3) also includes a bracket (33), insert rods (34) and slots (35). The bracket (33) is threaded onto the screw (36). The two insert rods (34) are fixedly connected to both ends of the bracket (33). The two slots (35) are opened on the heating cylinder (1). The two insert rods (34) are slidably connected to the inside of the two slots (35).

4. The thermal filtration treatment apparatus for trifluoromethylpyridine pharmaceutical intermediates according to claim 3, characterized in that: The pressurizing assembly (3) also includes a connecting block (37) and a rocker arm (38). The two connecting blocks (37) are respectively disposed on the bracket (33) and the piston (31). One connecting block (37) is fixedly connected to the bracket (33), and the other connecting block (37) is slidably connected to the piston (31). The two ends of the rocker arm (38) are rotatably connected to the two connecting blocks (37) respectively.

5. The thermal filtration treatment apparatus for trifluoromethylpyridine pharmaceutical intermediates according to claim 4, characterized in that: The pressurizing assembly (3) also includes a connecting ring (32), which is fixedly connected to the sealing ring (21) and slidably connected to the inner wall of the heating cylinder (1).

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