Electromagnetic separation and uniform mixing device for magnetic microspheres

Abstract

The utility model belongs to the technical field of biological detection and analysis devices, and provides an electromagnetic separation and blending device for magnetic microspheres in order to solve the technical problem that the magnetism of permanent magnets of an existing magnetic frame cannot be changed according to requirements, and the electromagnetic separation and blending device comprises a control platform, an electromagnetic separation device and a blending device, the uniform mixing device is connected with the switch box on the outer surface and comprises a base and a power assembly, the base is fixed to the control platform, the uniform mixing device is connected with the electromagnetic separation device through the power assembly, and the power assembly is connected with the switch box, so that the control module can control the electromagnetic separation device to vibrate; the electromagnets are connected in series with the control module and the switch box and used for controlling electrification and magnetic intensity of the electromagnets.

Description

Technical Field

[0001] This invention belongs to the technical field of biological detection and analysis devices. Background Technology

[0002] Magnetic microspheres, as a type of magnetic material, not only possess many of the properties of ordinary polymer microspheres but also exhibit magnetic responsiveness. Therefore, they are widely used in numerous fields such as biomedicine, cell biology, and separation engineering. For example, before sample analysis, magnetic microspheres are often used to separate and purify the target analytes within the sample, followed by further mixing, thereby achieving targeted extraction of the target analytes. Currently, most methods involve placing the sample on a magnetic rack to achieve the separation and purification of the target analytes, followed by mixing on a shaker.

[0003] However, the magnetism of the permanent magnet in the existing magnetic rack cannot be changed according to the needs. When the magnetism of the permanent magnet is too strong, it will cause the magnetic microspheres to agglomerate, or even cause irreversible agglomeration. This makes it difficult to mix the magnetic microspheres afterward, reducing the accuracy of biological detection and analysis. Utility Model Content

[0004] To address the technical problem that the magnetic strength of the permanent magnet of the magnetic frame cannot be changed according to the requirements, this utility model proposes a "magnetic microsphere electromagnetic separation and mixing device".

[0005] Magnetic microsphere electromagnetic separation and mixing device, such as Figure 1 As shown, the device includes a control platform 1, an electromagnetic separation device 2, and a mixing device 3. The control platform 1 includes an internal control module connected to a switch box 4 on the outer surface. The mixing device 3 includes a base 31 and a power assembly 32. The base 31 is fixed on the control platform 1. The mixing device 3 is connected to the electromagnetic separation device 2 through the power assembly 32. The power assembly 32 is connected to the switch box 4, enabling the control module to control the oscillation of the electromagnetic separation device 2. An electromagnet 5 is installed inside the electromagnetic separation device 2. Multiple electromagnets 5 are connected in series with the control module and the switch box 4 to control the energization and magnetic strength of the electromagnets.

[0006] Technical effects:

[0007] This invention connects multiple electromagnets in series in an electromagnetic separation device, and controls the current intensity of these electromagnets via a control module. This allows the magnetism of the electromagnets to be changed as needed, making the magnetic strength controllable and preventing the aggregation of magnetic microspheres, thus increasing the accuracy of biological detection and analysis. After the electromagnets are de-energized, the sample can be directly mixed on the electromagnetic separation and mixing device using a mixing device. The sample no longer needs to be transferred back and forth between the magnetic frame and the oscillator, saving operation steps, improving work efficiency, and solving the problem of the lack of an effective mixing and oscillation mechanism in existing equipment. Attached Figure Description

[0008] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0009] Figure 2 This is an enlarged schematic diagram of the switch box. Detailed Implementation

[0010] The technical solution will now be clearly and completely described with reference to the accompanying drawings in the embodiments of this utility model.

[0011] The electromagnetic separation device 2 comprises a top cover, a bottom plate, and a cylindrical wall forming a chamber, all made of a flexible, elastic material, allowing the power assembly 32 to drive the central part of the electromagnetic separation device 2 to oscillate. Rubber is preferred as the flexible material. Multiple electromagnets are equidistantly mounted on the bottom plate, and the top cover has multiple through holes. The positions of these through holes correspond vertically to the positions of the electromagnets 5, and the through hole sizes are suitable for sample tubes of different specifications, including 2ml, 5ml, 10ml, and 50ml.

[0012] The power assembly 32 includes a motor, an eccentric shaft, and a bearing. The motor is connected to the base 31. The eccentric shaft is mounted on the power output shaft of the motor. The bearing is sleeved on the outside of the eccentric shaft and connected to the inner wall below the electromagnetic separation device. The motor is used to drive the eccentric shaft so that the eccentric shaft drives the bearing to drive the electromagnetic separation device to vibrate and mix.

[0013] like Figure 2 As shown, the switch box 4 includes two self-locking push-button switches 41, two status indicator lights 42, a leakage current protection circuit breaker 43, and a power output socket 44. It is installed on the side of the control platform 1. The two push-button switches control the electromagnet and the power component respectively. For example, when the push-button switch of the power component is pressed, the status indicator light lights up and the motor starts at the same time. When the push-button switch is pressed again, the status indicator light goes out and the motor stops working at the same time. The control of the electromagnet is the same.

[0014] Furthermore, the inclusion of the leakage protection circuit breaker enhances the device's leakage protection performance and improves safety; the power output socket allows for the connection of external electrical control devices, increasing practicality.

[0015] The control module is a control circuit board, and the electrical control part therein is existing technology and will not be described in detail.

[0016] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A magnetic microsphere electromagnetic separation and mixing device, characterized in that, The device includes a control platform (1), an electromagnetic separation device (2), and a mixing device (3). The control platform (1) includes an internal control module connected to a switch box (4) on the outer surface. The mixing device (3) includes a base (31) and a power assembly (32). The base (31) is fixed on the control platform (1). The mixing device (3) is connected to the electromagnetic separation device (2) through the power assembly (32). The power assembly (32) is connected to the switch box (4) so ​​that the control module can control the oscillation of the electromagnetic separation device (2). An electromagnet (5) is installed inside the electromagnetic separation device (2). Multiple electromagnets (5) are connected in series with the control module and the switch box (4) to control the energization and magnetic strength of the electromagnets.

2. The electromagnetic separation and mixing device for magnetic microspheres according to claim 1, characterized in that, The electromagnetic separation device (2) includes an upper cover, a bottom plate, and a cylindrical wall forming a chamber, all made of flexible material with elasticity. Multiple electromagnets are equidistantly installed on the bottom plate. The upper cover has multiple through holes, and the positions of the through holes correspond vertically to the positions of the electromagnets (5).

3. The electromagnetic separation and mixing device for magnetic microspheres according to claim 1, characterized in that, The power assembly (32) includes a motor, an eccentric shaft and a bearing. The motor is connected to the base (31). The eccentric shaft is mounted on the power output shaft of the motor. The bearing is sleeved on the outside of the eccentric shaft and connected to the inner wall below the electromagnetic separation device. The motor is used to drive the eccentric shaft so that the eccentric shaft drives the bearing to drive the electromagnetic separation device to vibrate and mix.

4. The electromagnetic separation and mixing device for magnetic microspheres according to claim 1, characterized in that, The switch box (4) includes two self-locking push-button switches (41), two status indicator lights (42), a residual current circuit breaker (43), and a power output socket (44).

5. The electromagnetic separation and mixing device for magnetic microspheres according to claim 1, characterized in that, The control module is a control circuit board.

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