Detection device based on biosensor

Abstract

The utility model discloses a detection device based on biosensor, relates to pesticide residue detection field, including detection base and detection mechanism, the detection mechanism includes elevating beam, horizontal slide plate and biosensor, horizontal slide plate is provided on the elevating beam in sliding mode, biosensor is installed at the bottom of horizontal slide plate, and the horizontal slide plate is fixed on the elevating beam. Two sample tables are arranged on the detection base in the moving direction of the horizontal sliding plate in a spaced mode, the sample tables and the lifting beam have the freedom degree of moving in the height direction of the detection base, and the two sample tables alternately ascend to detection positions. According to the sample table, an operator can synchronously carry out sample replacement and preparation work on another sample table at a non-detection position, so that continuous detection work is realized, the intermittent operation mode of'detection-shutdown sample replacement-re-detection 'of a traditional single sample table is thoroughly changed, and the overall detection period of batch samples is greatly shortened.

Description

Technical Field

[0001] This utility model relates to the field of pesticide residue detection, specifically a detection device based on biosensors. Background Technology

[0002] Pesticide residue detection is a crucial step in ensuring food safety, environmental protection, and agricultural product quality. With increasing public concern about food safety, higher demands are being placed on the sensitivity, efficiency, and ease of operation of detection technologies. Biosensors, with their advantages of high specificity, rapid response, and low cost, have gradually become one of the core technologies in the field of pesticide residue detection. They convert biological signals into detectable physicochemical signals through the specific binding of biorecognition elements (such as enzymes, antibodies, and microorganisms) to pesticide molecules, enabling quantitative or qualitative analysis of pesticide residues.

[0003] However, traditional devices often employ a single sample stage design. When conducting batch testing of samples, after the previous sample is tested, it is necessary to wait for the next sample to be replaced before continuing the testing operation. The sample replacement process is cumbersome, requiring frequent manual handling of samples and making it impossible to form continuous testing operations. This results in an excessively long testing cycle, making it difficult to meet the needs of rapid batch testing, especially unsuitable for high-throughput testing scenarios such as agricultural product wholesale markets and customs quarantine. Secondly, the sample positioning accuracy is insufficient. Pesticide residue detection has strict requirements on the relative position of the biosensor and the sample. The sample stage of existing devices lacks stable guidance and quick limiting mechanisms. After the sample dish is placed, it is prone to displacement and shaking, resulting in insufficient contact or positional deviation between the detection end of the biosensor and the sample, which in turn affects the accuracy and repeatability of the test results. Utility Model Content

[0004] The purpose of this invention is to overcome the shortcomings of the prior art and provide a detection device based on biosensors to address the deficiencies of the prior art.

[0005] The purpose of this utility model is achieved through the following technical solution: a detection device based on a biosensor, including a detection base and a detection mechanism. The detection mechanism includes a lifting beam, a horizontal sliding plate, and a biosensor. The horizontal sliding plate is slidably mounted on the lifting beam. The biosensor is installed at the bottom of the horizontal sliding plate. Two sample stages are spaced apart on the detection base along the moving direction of the horizontal sliding plate. Both the sample stages and the lifting beam have the freedom to move along the height direction of the detection base. The two sample stages alternately rise to the detection position.

[0006] Furthermore, a drive cavity is provided inside the detection base, and a lifting rod is fixed to the bottom of the sample stage. The lifting rod is movably inserted into the drive cavity and connected to a rack. A gear is provided between the two racks, and both racks mesh with the gear. The gear is rotatably connected to the detection base through a main shaft. A motor is installed on the side wall of the detection base, and the output shaft of the motor is connected to the main shaft.

[0007] Furthermore, guide rails are vertically installed on both sides of the lifting rod, the guide rails are fixedly connected to the sample stage, and the detection base has through holes for the guide rails to pass through, the through holes being connected to the drive cavity.

[0008] Furthermore, a limiting groove is formed on the top surface of the sample stage, and the sample dish is placed in the limiting groove. Multiple pressure rods are slidably inserted through the side wall of the limiting groove along its own circumference.

[0009] Furthermore, an annular groove is formed around the limiting circular groove in the sample stage, and a drive ring is rotatably installed in the annular groove. The rotation axis of the drive ring is coaxial with the limiting circular groove. Multiple arc-shaped grooves are formed on the top surface of the drive ring, and each of the multiple arc-shaped grooves corresponds to a multiple pressure rod. The arc-shaped grooves are eccentrically set with the drive ring, and a drive shaft is provided in the arc-shaped groove. The pressure rod is fixedly connected to the drive shaft.

[0010] Furthermore, the end of the pressure rod away from the drive shaft is arc-shaped, and the side wall of the limiting circular groove is provided with a guide hole for the pressure rod to pass through.

[0011] Furthermore, the top surface of the sample stage is provided with a driving arc groove that connects to the annular groove. The driving arc groove is concentrically arranged with the driving ring. A lever is slidably arranged in the driving arc groove, and the lever is fixedly connected to the driving ring.

[0012] Furthermore, a tension spring is provided inside the annular groove, and the two ends of the tension spring are respectively connected to the sample stage and the drive ring.

[0013] Furthermore, the detection mechanism also includes a U-shaped bracket with its opening facing upwards. The lifting beam is located inside the opening of the U-shaped bracket. A guide rail is vertically fixed to the side wall of the U-shaped bracket, and a slide rail seat is slidably arranged on the guide rail. The slide rail seat is fixedly connected to the lifting beam. A linear drive device is vertically installed on the U-shaped bracket, and the telescopic shaft of the linear drive device is connected to the lifting beam.

[0014] Furthermore, the bottom surface of the lifting beam is provided with a lead screw groove, a lead screw is rotatably disposed in the lead screw groove, a lead screw slider is threadedly fitted on the lead screw, the lead screw slider is slidably adapted to the lead screw groove, a lead screw motor is installed on the lifting beam, and the output shaft of the lead screw motor is connected to the lead screw.

[0015] The beneficial effects of this utility model are:

[0016] 1. Employing a dual-sample-stage alternating operation design, the two sample stages can alternately rise to the detection position. During actual testing, while one sample stage is in the detection position working with the biosensor to complete the detection task, the operator can simultaneously perform sample replacement and preparation work on the other sample stage, which is not in the detection position. After the current sample is tested, there is no need to wait for sample replacement; by alternating the raising and lowering of the sample stages and the movement of the horizontal sliding plate, the operator can quickly switch to the next sample for testing. This continuous testing mode completely changes the intermittent operation mode of the traditional single-sample-stage "detection-stop for sample replacement-re-detection" process, significantly shortening the overall testing cycle for batch samples. It effectively meets the testing efficiency requirements of high-throughput testing scenarios such as agricultural product wholesale markets and customs quarantine, while reducing manual waiting time and lowering labor costs.

[0017] 2. The limiting groove on the top surface of the sample stage can initially position the sample dish. At the same time, multiple pressure rods sliding through the side wall of the limiting groove can clamp and fix the sample dish from the circumferential direction. The operation is simple and quick, and can effectively prevent the sample dish from shifting or tipping over due to vibration or movement of the mechanism during the test. This avoids the contamination problem caused by sample leakage and ensures the stable and orderly progress of the test operation. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the biosensor-based detection device of this utility model. Figure 1 ;

[0019] Figure 2 This is a schematic diagram of the internal structure of the detection base in the biosensor-based detection device of this utility model;

[0020] Figure 3 This is a schematic diagram of the biosensor-based detection device of this utility model. Figure 2 ;

[0021] Figure 4 This is a schematic diagram of the internal structure of the sample stage in the biosensor-based detection device of this utility model;

[0022] Figure 5 This is a schematic diagram of the biosensor-based detection device of this utility model. Figure 3

[0023] In the diagram, 1-detection base, 2-lifting beam, 3-horizontal slide plate, 4-biosensor, 5-sample stage, 6-drive cavity, 7-lifting rod, 8-rack, 9-gear, 10-spindle, 11-motor, 12-guide rail, 13-limiting groove, 14-pressure rod, 15-annular groove, 16-drive ring, 17-arc groove, 18-drive shaft, 19-guide hole, 20-drive arc groove, 21-lever, 22-tension spring, 23-U-shaped bracket, 24-guide rail, 25-linear drive device, 26-screw groove, 27-screw, 28-screw motor. Detailed Implementation

[0024] Example 1

[0025] like Figures 1 to 5 As shown, the biosensor-based detection device includes a detection base 1 and a detection mechanism. The detection mechanism includes a lifting beam 2, a horizontal sliding plate 3, and a biosensor 4. The horizontal sliding plate 3 is slidably mounted on the lifting beam 2, and the biosensor 4 is installed at the bottom of the horizontal sliding plate 3. Two sample stages 5 are spaced apart on the detection base 1 along the moving direction of the horizontal sliding plate 3. Both the sample stages 5 and the lifting beam 2 have the freedom to move along the height direction of the detection base 1. The two sample stages 5 alternately rise to the detection position. First, a sample dish is placed on the lower sample stage 5, which is lower in height to facilitate accurate placement of the sample dish. Then, the sample stage 5 carrying the sample dish moves upward to the detection position, while the sample stage 5 without the sample dish moves downward to the loading position. The movement of plate 3 causes the biosensor 4 to switch positions between the two sample stages 5. The lifting beam 2 drives the biosensor 4 to extend into the sample dish for pesticide residue detection. This detection method is a mature technology. The biosensor equipment can be directly installed on the horizontal sliding plate 3. While detecting, the next sample to be tested is placed on the lower sample stage 5. After the sample is tested, the two sample stages 5 switch positions, and the next sample can be tested directly without waiting for sample replacement. This achieves continuous detection operation, greatly shortens the overall detection cycle of batch samples, effectively meets the detection efficiency requirements of high-throughput detection scenarios such as agricultural product wholesale markets and customs quarantine, and reduces manual waiting time and labor costs.

[0026] Example 2

[0027] Based on Example 1, such as Figures 1 to 5As shown, the detection mechanism also includes a U-shaped bracket 23 with its opening facing upwards. The lifting beam 2 is located inside the opening of the U-shaped bracket 23. A guide rail 24 is vertically fixed to the side wall of the U-shaped bracket 23. A slide rail seat is slidably arranged on the guide rail 24. The slide rail seat is fixedly connected to the lifting beam 2. A linear drive device 25 is vertically installed on the U-shaped bracket 23. The telescopic shaft of the linear drive device 25 is connected to the lifting beam 2. The linear drive device 25 is a cylinder, hydraulic cylinder, or linear motor. The linear drive device 25 drives the lifting beam 2 to move up and down, so that the detection head of the biosensor 4 can be inserted into or removed from the sample dish.

[0028] Furthermore, the bottom surface of the lifting beam 2 is provided with a lead screw groove 26, and a lead screw 27 is rotatably installed in the lead screw groove 26. A lead screw slider is threaded onto the lead screw 27 and slides within the lead screw groove 26. A horizontal slide plate 3 is installed on the lead screw slider. A lead screw motor 28 is installed on the lifting beam 2. The output shaft of the lead screw motor 28 is connected to the lead screw 27. The lead screw motor 28 drives the lead screw 27 to rotate, causing the lead screw slider to drive the horizontal slide plate 3 to move linearly along the axial direction of the lead screw 27. This allows the horizontal slide plate 3 to drive the biosensor 4 to switch positions between the two sample stages 5, enabling the biosensor 4 to detect pesticide residues in the samples on the two sample stages 5.

[0029] Example 3

[0030] Based on Example 2, such as Figure 1 and Figure 2 As shown, a drive cavity 6 is provided inside the detection base 1, and a lifting rod 7 is fixed to the bottom of the sample stage 5. The lifting rod 7 is movably inserted into the drive cavity 6 and connected to a rack 8. A gear 9 is provided between the two racks 8, and both racks 8 mesh with the gear 9. The gear 9 is rotatably connected to the detection base 1 through a main shaft 10. A motor 11 is installed on the side wall of the detection base 1, and the output shaft of the motor 11 is connected to the main shaft 10. The motor 11 drives the gear 9 to rotate through the main shaft 10. Since the two racks 8 are arranged opposite each other and both racks 8 mesh with the gear 9, when the gear 9 drives one rack 8 to move upward, it simultaneously drives the other rack 8 to move downward. Thus, the two sample stages 5 can move in opposite directions through a single drive source, realizing the alternating switching between loading and detection of the two sample stages 5.

[0031] Furthermore, guide rails 12 are vertically installed on both sides of the lifting rod 7. The guide rails 12 are fixedly connected to the sample stage 5. The detection base 1 has through holes for the guide rails 12 to pass through. The through holes are connected to the drive cavity 6. The guide rails 12 guide the movement of the sample stage 5, making the movement of the sample stage 5 more stable.

[0032] Example 4

[0033] Based on Example 3, such as Figures 1 to 4 As shown, a limiting groove 13 is formed on the top surface of the sample stage 5. The sample dish is placed in the limiting groove 13. Multiple pressure rods 14 slide along the side wall of the limiting groove 13 in its circumferential direction. An annular groove 15 is formed around the limiting groove 13 inside the sample stage 5. A drive ring 16 is rotatably installed in the annular groove 15. The rotation axis of the drive ring 16 is coaxial with the limiting groove 13. Multiple arc-shaped grooves 17 are formed on the top surface of the drive ring 16. Each arc-shaped groove 17 corresponds to one of the multiple pressure rods 14. The arc-shaped grooves 17 are eccentrically set with the drive ring 16. A drive shaft 18 is set in the arc-shaped groove 17. The pressure rods 14 are fixedly connected to the drive shaft 18. The end of the rod 14 away from the drive shaft 18 is arc-shaped. The side wall of the limiting groove 13 is provided with a guide hole 19 for the pressure rod 14 to pass through. Initially, the pressure rod 14 is not inserted into the limiting groove 13. The sample dish is placed into the limiting groove 13, and then the drive ring 16 is rotated to guide the pressure rod 14 through the guide hole 19. This causes the arc-shaped groove 17 to drive the pressure rod 14 to move closer to the sample dish through the drive shaft 18, thereby clamping the sample dish in the limiting groove 13. This effectively prevents the sample dish from shifting or tipping over due to vibration or movement of the mechanism during the detection process, thus avoiding the contamination problem caused by sample leakage and ensuring the stable and orderly progress of the detection operation.

[0034] Example 5

[0035] Based on Example 4, such as Figures 1 to 4 As shown, the top surface of the sample stage 5 is provided with a driving arc groove 20 that connects to the annular groove 15. The driving arc groove 20 is concentrically arranged with the driving ring 16. A lever 21 is slidably arranged in the driving arc groove 20 and is fixedly connected to the driving ring 16. A tension spring 22 is arranged in the annular groove 15. The two ends of the tension spring 22 are respectively connected to the sample stage 5 and the driving ring 16. When the tension spring 22 is in the normal state, the arc end of the pressure rod 14 extends into the limiting circular groove 13. When placing the sample dish, the lever 21 is deflected, causing the lever 21 to drive the driving ring 16 to deflect, causing the driving ring 16 to stretch the tension spring 22 and move the pressure rod 14 into the guide hole 19, so that the sample dish can be smoothly placed into the limiting circular groove 13. Then the lever 21 is released, and the driving ring 16 is reset under the force of the tension spring 22, so that the pressure rod 14 presses against the sample dish under the action of the tension spring 22, realizing the clamping and limiting of the sample dish and improving the stability of the detection.

Claims

1. A detection device based on a biosensor, characterized in that, The device includes a detection base (1) and a detection mechanism. The detection mechanism includes a lifting beam (2), a horizontal sliding plate (3), and a biosensor (4). The horizontal sliding plate (3) is slidably mounted on the lifting beam (2). The biosensor (4) is mounted on the bottom of the horizontal sliding plate (3). Two sample stages (5) are spaced apart on the detection base (1) along the moving direction of the horizontal sliding plate (3). Both the sample stages (5) and the lifting beam (2) have the freedom to move along the height direction of the detection base (1). The two sample stages (5) alternately rise to the detection position.

2. The biosensor-based detection device according to claim 1, characterized in that, The detection base (1) is provided with a drive cavity (6), and the bottom of the sample stage (5) is fixed with a lifting rod (7). The lifting rod (7) is movably inserted into the drive cavity (6) and connected to a rack (8). A gear (9) is provided between the two racks (8). Both racks (8) mesh with the gear (9). The gear (9) is rotatably connected to the detection base (1) through the main shaft (10). A motor (11) is installed on the side wall of the detection base (1). The output shaft of the motor (11) is connected to the main shaft (10).

3. The biosensor-based detection device according to claim 2, characterized in that, The lifting rod (7) has vertical guide rails (12) on both sides. The guide rails (12) are fixedly connected to the sample stage (5). The detection base (1) has through holes for the guide rails (12) to pass through. The through holes are connected to the drive cavity (6).

4. The biosensor-based detection device according to claim 1, characterized in that, The top surface of the sample stage (5) is provided with a limiting circular groove (13), and the sample dish is placed in the limiting circular groove (13). Multiple pressure rods (14) are slidably passed through the side wall of the limiting circular groove (13) along its own circumference.

5. The biosensor-based detection device according to claim 4, characterized in that, An annular groove (15) is provided inside the sample stage (5) around the limiting circular groove (13). A drive ring (16) is rotatably installed inside the annular groove (15). The rotation axis of the drive ring (16) is coaxial with the limiting circular groove (13). Multiple arc-shaped grooves (17) are provided on the top surface of the drive ring (16). The multiple arc-shaped grooves (17) correspond one-to-one with multiple pressure rods (14). The arc-shaped grooves (17) and the drive ring (16) are eccentrically arranged. A drive shaft (18) is provided inside the arc-shaped grooves (17). The pressure rods (14) are fixedly connected to the drive shaft (18).

6. The biosensor-based detection device according to claim 5, characterized in that, The end of the pressure rod (14) away from the drive shaft (18) is arc-shaped, and the side wall of the limiting circular groove (13) is provided with a guide hole (19) for the pressure rod (14) to pass through.

7. The biosensor-based detection device according to claim 5, characterized in that, The top surface of the sample stage (5) is provided with a driving arc groove (20) that connects to the annular groove (15). The driving arc groove (20) is concentrically arranged with the driving ring (16). A lever (21) is slidably arranged in the driving arc groove (20). The lever (21) is fixedly connected to the driving ring (16).

8. The biosensor-based detection device according to claim 7, characterized in that, A tension spring (22) is provided in the annular groove (15), and the two ends of the tension spring (22) are respectively connected to the sample stage (5) and the drive ring (16).

9. The biosensor-based detection device according to claim 1, characterized in that, The detection mechanism also includes a U-shaped bracket (23), the opening of which is facing upwards. The lifting beam (2) is located inside the opening of the U-shaped bracket (23). A guide rail (24) is vertically fixed to the side wall of the U-shaped bracket (23). A slide rail seat is slidably arranged on the guide rail (24). The slide rail seat is fixedly connected to the lifting beam (2). A linear drive device (25) is vertically installed on the U-shaped bracket (23). The telescopic shaft of the linear drive device (25) is connected to the lifting beam (2).

10. The biosensor-based detection device according to claim 9, characterized in that, The bottom surface of the lifting beam (2) is provided with a lead screw groove (26), and a lead screw (27) is rotatably arranged in the lead screw groove (26). A lead screw slider is threaded on the lead screw (27), and the lead screw slider is slidably adapted to the lead screw groove (26). The horizontal slide plate (3) is installed on the lead screw slider. A lead screw motor (28) is installed on the lifting beam (2), and the output shaft of the lead screw motor (28) is connected to the lead screw (27).

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