Sample incubation device for immunodetection equipment and immunodetection equipment

Abstract

The utility model discloses a sample incubation device for immunodetection equipment and the immunodetection equipment. The sample incubation device comprises a base, a sample incubation device and a sample incubation device, the incubation module and the sample module are respectively and movably arranged on the base and are arranged side by side along the moving direction; the connecting module comprises a buckle assembly and a connecting piece, the buckle assembly is arranged on the side, facing the sample module, of the incubation module, and the connecting piece is arranged on the side, facing the incubation module, of the sample module and detachably connected with the buckle assembly; the driving part is in driving connection with the incubation module. The sample incubation device for the immunodetection equipment has the advantages that the structure is simple, the occupied space and the manufacturing cost are reduced, and miniaturization design is facilitated.

Description

Technical Field

[0001] This application belongs to the field of immunoassay equipment technology, specifically relating to a sample incubation device and immunoassay equipment for use in immunoassay equipment. Background Technology

[0002] The design of the incubation module and sample module of existing immunoassay devices (such as chemiluminescence immunoassay analyzers) and the driving mechanism that drives the above two modules is not reasonable enough. As a result, the overall layout of the sample incubation device and immunoassay device occupies a large space and has high manufacturing cost. It has low versatility in clinical departments and emergency laboratory settings, which is not conducive to the promotion and use of immunoassay devices. Utility Model Content

[0003] The purpose of this application is to provide a sample incubation device and an immunoassay device for use in immunoassay equipment. The sample incubation device for immunoassay equipment has the advantages of simple structure, reduced space occupation and manufacturing cost, and facilitates miniaturization design.

[0004] To achieve the above objectives, the first aspect of this application provides a sample incubation apparatus for an immunoassay device, the sample incubation apparatus comprising:

[0005] Base;

[0006] The incubation module and the sample module are movably mounted on the base and arranged side by side along the direction of movement;

[0007] The connection module includes a snap-fit ​​assembly and a connector. The snap-fit ​​assembly is located on the side of the incubation module facing the sample module, and the connector is located on the side of the sample module facing the incubation module and is detachably connected to the snap-fit ​​assembly.

[0008] The driver is connected to the incubation module driver.

[0009] In embodiments of this application, the snap-fit ​​assembly includes:

[0010] The housing has an internal receiving groove with an opening facing the connector;

[0011] The engaging member is movably disposed in the receiving groove, and a locking space is formed on the engaging member that can be opened and closed to accommodate the locking end of the connecting member.

[0012] In embodiments of this application, the sample incubation device further includes a plurality of support members disposed below the base and used to jointly support the base, a first space being formed between the plurality of support members, and a driving member being disposed vertically in the first space.

[0013] In embodiments of this application, a second space recessed from top to bottom is formed on the base, and the sample incubation device further includes:

[0014] The drive wheel is horizontally positioned in the second space and is driven by the drive components.

[0015] The driven wheel is arranged horizontally in the second space and is spaced apart from the driving wheel along the length of the base;

[0016] The drive belt is fitted over the outside of the driving and driven pulleys, and the incubation module is connected to the drive belt.

[0017] In an embodiment of this application, a hollow portion is formed on the bottom wall of the second space.

[0018] In embodiments of this application, the sample incubation apparatus further includes:

[0019] The guide rail is set on the base and located on one side of the width direction of the second space. The direction of the guide rail is distributed with the length direction of the base.

[0020] The first slider is movably mounted on the guide rail and connected to the incubation module;

[0021] The second slider is movably mounted on the guide rail and connected to the sample module.

[0022] In embodiments of this application, the sample incubation device further includes a first magnetic component and a second magnetic component. The first magnetic component is disposed on the side of the sample module away from the incubation module, and the second magnetic component is disposed on the base and is used to magnetically connect with the first magnetic component.

[0023] In embodiments of this application, the sample incubation apparatus further includes:

[0024] The first baffle is set on the incubation module;

[0025] The first detection piece is set on the base and located at the suction station, and is used to detect whether the first baffle has reached the suction station.

[0026] In embodiments of this application, the sample incubation apparatus further includes:

[0027] The second baffle is set on the incubation module and is close to the sample module of the first baffle;

[0028] The second inspection piece is set on the base and located at the connection station, and is used to detect whether the second baffle has reached the connection station.

[0029] A second aspect of this application provides an immunoassay device, which includes the sample incubation apparatus described above for use in immunoassay devices.

[0030] As shown in the above technical solution, the sample incubation device includes a base, an incubation module, a sample module, a connecting module, and a driving component. The incubation module and the sample module are movably mounted on the base and arranged side-by-side along the direction of movement. The connecting module includes a snap-fit ​​assembly and a connector. The snap-fit ​​assembly is located on the side of the incubation module facing the sample module, and the connector is located on the side of the sample module facing the incubation module and is detachably connected to the snap-fit ​​assembly. The driving component is driven to connect with the incubation module. By providing detachable snap-fit ​​assemblies and connectors on the incubation module and the sample module respectively, the sample incubation device requires only one driving component to achieve the simultaneous movement of both the incubation module and the sample module or the movement of the incubation module alone. This reduces the number of components in the sample incubation device, reduces the overall space occupied by the sample incubation device and the manufacturing cost, and helps to reduce the size of the sample incubation device and the immunoassay device. In addition, the above configuration also allows the immunoassay device to only require one sample aspiration module to aspirate the sample and reagents into the incubation module respectively, reducing the number of components in the immunoassay device, which helps to further reduce the overall size of the immunoassay device and improve the versatility and applicability of the immunoassay device.

[0031] Other features and advantages of the embodiments of this application will be described in detail in the following detailed description section. Attached Figure Description

[0032] The accompanying drawings are provided to further illustrate the embodiments of this application and form part of the specification. They are used together with the following detailed description to explain the embodiments of this application, but do not constitute a limitation on the embodiments of this application. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without any inventive effort. In the drawings:

[0033] Figure 1 This is a schematic diagram of the sample incubation device from a first-view perspective in an embodiment of this application;

[0034] Figure 2 This is a schematic diagram of the sample incubation device from a second perspective in an embodiment of this application;

[0035] Figure 3 This is a schematic diagram of the sample incubation device from a third-view perspective in an embodiment of this application;

[0036] Figure 4 This is a partial structural schematic diagram of the sample incubation device in an embodiment of this application.

[0037] Explanation of reference numerals in the attached figures

[0038] 1-Base; 101-Second space; 102-Hollowed-out part; 2-Incubation module; 3-Sample module; 301-Sample carrier; 302-Sample tube; 4-Connecting module; 401-Snap-on assembly; 402-Connector; 5-Driver; 6-Support; 601-First space; 7-Driving wheel; 8-Driven wheel; 9-Transmission belt; 10-Guide rail; 11-First slider; 12-Second slider; 13-First magnetic component; 14-Second magnetic component; 15-First baffle; 16-First detection component; 17-Second baffle; 18-Second detection component. Detailed Implementation

[0039] The specific embodiments of this application will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit this application.

[0040] Embodiments of this application provide a sample incubation device for an immunoassay device, such as... Figures 1-3 As shown, the sample incubation device includes:

[0041] Base 1;

[0042] The incubation module 2 and the sample module 3 are movably mounted on the base 1 and arranged side by side along the direction of movement;

[0043] The connection module 4 includes a snap-fit ​​assembly 401 and a connector 402. The snap-fit ​​assembly 401 is disposed on the side of the incubation module 2 facing the sample module 3, and the connector 402 is disposed on the side of the sample module 3 facing the incubation module 2 and is detachably connected to the snap-fit ​​assembly 401.

[0044] Driver 5 is connected to incubation module 2.

[0045] Specifically, the immunoassay device in this embodiment can be a chemiluminescence immunoassay analyzer. The sample module 3 includes a sample tube 302 and a sample holder 301 for loading the sample tube 302. The sample tube 302 is used to hold the sample. The incubation module 2 is used to incubate the sample and reagents. The drive component 5 can be a motor. Further, the immunoassay device in this embodiment also includes a sample aspiration module and a reagent module. The sample aspiration module is vertically and vertically mounted at one end of the base 1 along its length and can move along the width of the base 1. The reagent module is located on one side of the sample incubation device and is used to hold the reagents.

[0046] When samples and reagents need to be drawn into incubation module 2 for incubation, drive component 5 drives incubation module 2 to move towards sample module 3, so that the latching component 401 on incubation module 2 and the connector 402 on sample module 3 are connected together. After the latching component 401 and connector 402 are connected, drive component 5 drives incubation module 2 with sample module 3 to move towards the aspiration module, so that the aspiration module can perform aspiration operation. After the aspiration operation is completed, drive component 5 drives incubation module 2 with sample module 3 back to the initial position, so that the latching component 401 and connector 402 are separated and the sample tube 302 on sample module 3 is replaced. Further, after the latching component 401 and connector 402 are separated, drive component 5 can drive incubation module 2 to move away from sample module 3 again according to actual needs. For example, drive incubation module 2 to move below aspiration module, so that aspiration module can perform reagent aspiration operation (in this embodiment, reagent aspiration operation means using aspiration module to draw reagents from reagent module into incubation module 2).

[0047] In this embodiment, the sample incubation device, by providing detachable snap-fit ​​components 401 and connectors 402 on the incubation module 2 and sample module 3 respectively, allows the device to achieve joint movement of both incubation module 2 and sample module 3 or individual movement of incubation module 2 with only one driving component 5. This reduces the number of components in the sample incubation device, thereby reducing the overall space occupied and manufacturing cost, and contributing to a smaller size for both the sample incubation device and the immunoassay device. Furthermore, the above-mentioned design allows the immunoassay device to require only one aspiration module to separately aspirate samples and reagents into the incubation module 2, further reducing the number of components and improving the overall size of the immunoassay device, thus enhancing its versatility and applicability.

[0048] In one embodiment of this application, the snap-fit ​​assembly 401 includes:

[0049] The housing has an internal receiving groove with an opening facing the connector 402;

[0050] The engaging member is movably disposed in the receiving groove, and a locking space is formed on the engaging member that can be opened and closed to accommodate the locking end of the connecting member 402.

[0051] Specifically, in this embodiment, the connector 402 can be selected as a ball catch (the locking end of the connector 402 is the locking ball of the ball catch), and the engaging component includes a slide body, an engaging body, an elastic body (not shown in the figure), and a sliding claw body, all of which are disposed in the receiving groove. A closed M-shaped pressing self-locking groove is formed on the slide body; the engaging body is hinged to the end of the slide body facing the connector 402 and is used to lock the connector 402; the elastic body can be selected as a torsion spring and is located at the end of the receiving groove away from the engaging body, and is used to drive the engaging body to move to open the locking space; one end of the sliding claw body is connected to the housing, and the other end passes through the inside of the elastic body and slides in cooperation with the M-shaped pressing self-locking groove, and is used to drive the slide body to slide out or move into the receiving groove. When the incubation module 2 and the sample module 3 need to be connected, the incubation module 2 moves toward the sample module 3 and the connector 402 presses the locking member with a first preset force. The connector 402 pushes the locking body and the slide body together into the receiving groove. As the locking body slides in, the opening of the receiving groove of the housing forces the slide body and the locking body to close and hold the connector 402 (i.e., close the locking space). At the same time, the sliding claw moves along the sliding section on the upper side of the M-shaped pressing self-locking groove. After moving to the end, the external force is removed, the elastic body rebounds against the slide body, and the sliding claw then slides into and locks into the M-shaped recess in the middle of the M-shaped pressing self-locking groove, locking the connector 402. When it is necessary to separate the incubation module 2 and the sample module 3, the incubation module 2 moves toward the sample module 3 and the connector 402 presses the locking member with a second preset force (in this embodiment, the second preset force is greater than the first preset force). The sliding claw slides out to the sliding section under the M-shaped pressing self-locking groove, and then the incubation module 2 stops moving toward the sample module 3 to remove the second preset force. The elastic body pushes against the sliding body and pops out together with the locking member. When the locking member slides out of the opening of the receiving groove, the connector 402 is opened and released, and the connector 402 and the locking member are separated.

[0052] In another embodiment of this application, the connecting module 4 may also be a press-type bead, a press-type ball buckle, or a press-type lock that can be purchased directly. The press-type bead, press-type ball buckle, and press-type lock all have a detachable buckle assembly 401 and a connector 402, and all have self-locking and spring-opening functions.

[0053] In one embodiment of this application, the sample incubation device further includes a plurality of support members 6 disposed below the base 1 and used to jointly support the base 1, a first space 601 is formed between the plurality of support members 6, and a drive member 5 is disposed vertically in the first space 601.

[0054] Specifically, in this embodiment, there are two support members 6. The two support members 6 are distributed at intervals along the length of the base 1 below the base 1. A first space 601 is formed between the two support members 6. The drive member 5 is vertically arranged in the first space 601 and connected to the bottom of the base 1. The above arrangement ensures that the installation of the drive member 5 does not increase the overall size of the sample incubation device, thereby improving the utilization rate of the internal space of the sample incubation device.

[0055] In one embodiment of this application, such as Figure 4 As shown, a second space 101 is formed on the base 1, which is recessed from top to bottom. The sample incubation device also includes:

[0056] The drive wheel 7 is horizontally positioned in the second space 101 and is driven by the drive component 5.

[0057] The driven wheel 8 is arranged horizontally in the second space 101 and is distributed at intervals with the driving wheel 7 along the length of the base 1.

[0058] The transmission belt 9 is fitted on the outside of the driving wheel 7 and the driven wheel 8, and the incubation module 2 is connected to the transmission belt 9.

[0059] Specifically, the second space 101 is recessed downwards from the top surface of the base 1 and is in the shape of a groove. The length direction of the second space 101 is consistent with the length direction of the base 1. The driving wheel 7 is located in the second space 101 at the end of the base 1 away from the sample absorption module, and the driven wheel 8 is located in the second space 101 at the end of the base 1 close to the sample absorption module. When the driving component 5 rotates, it drives the driving wheel 7, the transmission belt 9, and the driven wheel 8 to rotate. The transmission belt 9 then drives the incubation module 2 to move along the length direction of the base 1. The driving wheel 7, the transmission belt 9, and the driven wheel 8 are located in the recessed second space 101 on the base 1 without increasing the overall size of the sample incubation device. This enhances the compactness of the installation between the components of the sample incubation device and is conducive to realizing the miniaturization design of the sample incubation device.

[0060] In one embodiment of this application, a hollow portion 102 is formed on the bottom wall of the second space 101. Specifically, the driving end of the driving member 5 passes through the hollow portion 102 and is connected to the driving wheel 7. The hollow portion 102 helps to reduce the material used in the sample incubation device and reduce the overall weight of the sample incubation device, which is beneficial to achieving a lightweight design of the sample incubation device.

[0061] In one embodiment of this application, the sample incubation apparatus further includes:

[0062] The guide rail 10 is set on the base 1 and located on one side of the width direction of the second space 101. The setting direction of the guide rail 10 is distributed with the length direction of the base 1.

[0063] The first slider 11 is movably mounted on the guide rail 10 and connected to the incubation module 2;

[0064] The second slider 12 is movably mounted on the guide rail 10 and connected to the sample module 3.

[0065] Specifically, in this embodiment, there are two guide rails 10, two first sliders 11, and two second sliders 12. The two guide rails 10 are respectively positioned above each other on both sides of the width direction of the second space 101. The two first sliders 11 are movably mounted on the two guide rails 10, with one first slider 11 connected to one side of the width direction of the incubation module 2 and the other first slider 11 connected to the other side of the width direction of the incubation module 2. Similarly, the two second sliders 12 are movably mounted on the two guide rails 10, with one second slider 12 connected to one side of the width direction of the sample module 3 and the other second slider 12 connected to the other side of the width direction of the sample module 3. This configuration enhances the connection stability and smoothness of movement between the incubation module 2, the sample module 3, and other components, further improving the practicality of the sample incubation device.

[0066] In one embodiment of this application, the sample incubation device further includes a first magnetic element 13 and a second magnetic element 14. The first magnetic element 13 is disposed on the side of the sample module 3 away from the incubation module 2, and the second magnetic element 14 is disposed on the base 1 and is used to magnetically connect with the first magnetic element 13.

[0067] Specifically, both the first magnetic component 13 and the second magnetic component 14 are made of magnets. The second magnetic component 14 is located at the end of the base 1 furthest from the sample suction module. When the incubation module 2 is not connected to the sample module 3, the first magnetic component 13 and the second magnetic component 14 are attracted together, thus keeping the sample module 3 stable on the base 1 and preventing it from moving arbitrarily due to external forces. This improves the ease of connection between the snap-fit ​​assembly 401 and the connector 402. When the incubation module 2 is connected to the sample module 3 and needs to be moved, the incubation module 2 and the sample module 3 are subjected to a pulling force towards the sample suction module under the driving action of the driving component 5. When this pulling force is greater than the attraction force between the first magnetic component 13 and the second magnetic component 14, the first magnetic component 13 and the second magnetic component 14 separate, allowing the sample module 3 to move along with the incubation module 2. The above structure is simple and allows the sample module 3 to switch between a stable state and a moving state according to usage requirements.

[0068] In one embodiment of this application, the sample incubation apparatus further includes:

[0069] The first baffle 15 is set on the incubation module 2;

[0070] The first detection piece 16 is set on the base 1 and located at the suction station, and is used to detect whether the first baffle 15 has reached the suction station.

[0071] Specifically, the first baffle 15 is disposed on the vertical side wall of the incubation module 2, and the first detection element 16 can be a photoelectric sensor and is located on the vertical side wall of the base 1. An aspiration station is formed on the guide rail 10. When the first baffle 15 extends into the detection groove of the first detection element 16, it can be detected by the first detection element 16, indicating that the first baffle 15 has reached the aspiration station. The incubation module 2 can cooperate with the aspiration module at the current position to perform aspiration operation or reagent aspiration operation. It is not appropriate to continue moving. The first baffle and the first detection element 16 are set to restrict the movement of the incubation module 2 toward the direction of the aspiration module, so as to prevent the incubation module 2 and the sample module 3 from falling off the guide rail 10.

[0072] In one embodiment of this application, the sample incubation apparatus further includes:

[0073] The second baffle 17 is disposed on the incubation module 2 and is close to the sample module 3 of the first baffle 15;

[0074] The second detection component 18 is set on the base 1 and located at the connection station, and is used to detect whether the second baffle 17 has reached the connection station.

[0075] Specifically, the second detection element 18 can be a photoelectric sensor and is located on the vertical side wall of the base 1. A connection station is formed on the guide rail 10. When the second baffle 17 extends into the detection groove of the second detection element 18, it can be detected by the second detection element 18, indicating that the second baffle 17 has reached the connection station. The incubation module 2 can connect or separate from the sample module 3 at the current position. It is not suitable to continue moving away from the sampling module. The second detection element 18 is set to restrict the movement of the incubation module 2 away from the sampling module.

[0076] Another embodiment of this application provides an immunoassay device, which includes the sample incubation device for immunoassay devices described in the above embodiments.

[0077] In the description of this application, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0078] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between components; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0079] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0080] Although embodiments of this application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting this application. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of this application.

Claims

1. A sample incubation device for an immunoassay detector, characterized in that, The sample incubation device includes: Base (1); The incubation module (2) and the sample module (3) are respectively movably mounted on the base (1) and arranged side by side along the moving direction; The connecting module (4) includes a snap-fit ​​assembly (401) and a connector (402). The snap-fit ​​assembly (401) is disposed on the side of the incubation module (2) facing the sample module (3), and the connector (402) is disposed on the side of the sample module (3) facing the incubation module (2) and is detachably connected to the snap-fit ​​assembly (401). The driving component (5) is driven to be connected to the incubation module (2).

2. The sample incubation device for an immunoassay device according to claim 1, characterized in that, The snap-fit ​​assembly (401) includes: The housing has an internal receiving groove with an opening facing the connector (402); A locking member is movably disposed in the receiving groove, and the locking member has an opening and closing locking space for accommodating the locking end of the connector (402).

3. The sample incubation device for an immunoassay device according to claim 1, characterized in that, The sample incubation device further includes a plurality of support members (6) disposed below the base (1) and used to jointly support the base (1), a first space (601) is formed between the plurality of support members (6), and the drive member (5) is disposed vertically in the first space (601).

4. The sample incubation device for an immunoassay device according to claim 3, characterized in that, A second space (101) is formed on the base (1) that is recessed from top to bottom, and the sample incubation device further includes: The drive wheel (7) is arranged horizontally in the second space (101) and is drivenly connected to the drive member (5); The driven wheel (8) is arranged horizontally in the second space (101) and is spaced apart from the driving wheel (7) along the length of the base (1); A drive belt (9) is fitted on the outside of the drive wheel (7) and the driven wheel (8), and the incubation module (2) is connected to the drive belt (9).

5. The sample incubation device for an immunoassay device according to claim 4, characterized in that, A hollow section (102) is formed on the bottom wall of the second space (101).

6. The sample incubation device for an immunoassay device according to claim 4, characterized in that, The sample incubation device also includes: A guide rail (10) is disposed on the base (1) and located on one side of the width direction of the second space (101). The arrangement direction of the guide rail (10) is distributed with the length direction of the base (1). The first slider (11) is movably disposed on the guide rail (10) and connected to the incubation module (2); The second slider (12) is movably mounted on the guide rail (10) and connected to the sample module (3).

7. The sample incubation device for an immunoassay device according to claim 1, characterized in that, The sample incubation device further includes a first magnetic component (13) and a second magnetic component (14). The first magnetic component (13) is disposed on the side of the sample module (3) away from the incubation module (2), and the second magnetic component (14) is disposed on the base (1) and is used to magnetically connect with the first magnetic component (13).

8. The sample incubation apparatus for an immunoassay device according to any one of claims 1-7, characterized in that, The sample incubation device also includes: A first baffle (15) is disposed on the incubation module (2); The first detection element (16) is set on the base (1) and located at the suction station, and is used to detect whether the first baffle (15) has reached the suction station.

9. The sample incubation device for an immunoassay device according to claim 8, characterized in that, The sample incubation device also includes: A second baffle (17) is disposed on the incubation module (2) and is located near the sample module (3) on the first baffle (15); The second detection element (18) is set on the base (1) and located at the connection station, and is used to detect whether the second baffle (17) has reached the connection station.

10. An immunoassay device, characterized in that, The immunoassay device includes a sample incubation apparatus for immunoassay devices according to any one of claims 1-9.

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