Filtering device for serum pretreatment

Abstract

The utility model discloses a filtering device for serum pretreatment, which relates to the technical field of filtering devices and comprises a cavity, the top of the cavity is in threaded connection with an upper cover, a sleeve plug is arranged in the middle of the inside of the cavity, and the outer surface of the top of the sleeve plug is sleeved with a stainless steel framework. A wire-wound filter element is arranged on the outer surface of the stainless steel framework, a feeding pipe is arranged at the top of the upper cover, the bottom of the feeding pipe extends to one side of the wire-wound filter element in the cavity, a clamping block is arranged at the top of the feeding pipe, a pressurizing pipe is arranged on one side of the cavity, and a bottom plate is arranged at the bottom end of the cavity; the bottom of the sleeve plug penetrates through the bottom plate of the cavity and extends to the bottom of the bottom plate. According to the filter device for serum pretreatment, a series of structures are arranged, so that serum can be completely filtered by the filter device for serum pretreatment, the filter membrane is prevented from being blocked by larger particles and impurities in the serum to influence the filtering effect, the filter device is convenient to disassemble and replace, and the operation steps are simple and efficient.

Description

TECHNICAL FIELD

[0001] The utility model relates to filter device technical field, concretely is a kind of filter device for serum pretreatment. BACKGROUND

[0002] In the cell culture process, serum is a very important component, it provides a variety of nutrient components required for cell growth, however, serum can also contain impurities, such as microorganisms, protein precipitation, etc., these impurities can affect the success rate of cell culture and the repeatability of results, therefore, the serum needs to be filtered.

[0003] At present, serum filtration is mostly using 0.2 μm cellulose acetate filter membrane to directly filter to remove impurities and microorganisms in serum, but because the filter membrane is thin, the impurities in serum can accumulate at the top of the filter screen when filtering, affecting the filtering effect. SUMMARY

[0004] The utility model aims at providing a kind of filter device for serum pretreatment to solve the problems raised in the above background.

[0005] To achieve the above object, the utility model provides the following technical scheme: a kind of filter device for serum pretreatment, including cavity, the top of the cavity is threadedly connected with upper cover, the inside intermediate position of the cavity is provided with bushing, the top outer surface of the bushing is sleeved with stainless steel framework, the outer surface of the stainless steel framework is provided with wire-wound filter core, the top of the upper cover is provided with feeding pipe, and the bottom of feeding pipe extends to the side of wire-wound filter core inside cavity, the top of the feeding pipe is provided with clamping block, one side of the cavity is provided with pressurizing pipe, the bottom end of the cavity is provided with bottom plate, the bottom of the bushing extends to the bottom of bottom plate and penetrates the bottom plate of cavity, the extension end of the bushing is threadedly connected with sleeve pipe, the inside of the sleeve pipe is provided with filter membrane, the bottom of the sleeve pipe is threadedly connected with serum discharge pipe.

[0006] Preferably, the top of the clamping block is provided with upper column, the upper column is L-shaped component, the bottom of the upper column is sleeved with bottom column, the bottom end of the bottom column is provided with cross bar, the one end of the cross bar is hingedly installed with support, the one end of the support is connected with the outer surface of feeding pipe and the connecting column, the bottom of clamping block is matched with feeding pipe, when clamping block is clamped in the top of feeding pipe, the inside of cavity is in sealed state, when pulling out clamping block and connecting hose to convey blood in the top of feeding pipe, the bottom of upper column extends upward from the inside of bottom column, then rotate clamping block to leave the top of feeding pipe through support, to facilitate connecting hose in the top of feeding pipe.

[0007] Preferably, the connecting column is provided with a limiting block at the side edge close to the crossbar position, when the clamping block is rotated to the top of the feeding pipe, the crossbar is blocked by the limiting block and cannot continue to rotate, facilitating the installation of the clamping block on the top of the feeding pipe, and guaranteeing the sealing property of the cavity.

[0008] Preferably, the bottom plate is provided with a support column at the bottom of each corner, and the bottom ends of the four support columns are connected with a base, so that the serum pretreatment filter device can be stably placed on a plane, and the support column lifts the bottom plate, so that the bottom of the serum discharge pipe has a certain height, facilitating the placement of the serum storage device below the serum discharge pipe.

[0009] Preferably, the outer surface of the sleeve plug inside the cavity is provided with two rubber rings, and the top of the sleeve plug is matched with the stainless steel framework, so that when the stainless steel is inserted into the sleeve plug, the rubber ring is attached to the inner wall of the stainless steel framework, reducing the gap and improving the sealing property.

[0010] Preferably, the top outer surface of the wire-wound filter element is provided with a metal cover, and the top end of the metal cover is provided with an auxiliary handle, so that the top of the wire-wound filter element is protected, the blood injected into the cavity is prevented from adhering to the top of the wire-wound filter element and affecting filtration, and the wire-wound filter element can be pulled out through the auxiliary handle when it is disassembled, so that the steps are simple and the operation is convenient.

[0011] Compared with the prior art, the blood serum pretreatment filter device has the following beneficial effects:

[0012] 1. The blood serum pretreatment filter device is provided with a wire-wound filter element inside the cavity and a sleeve at the bottom of the sleeve plug, so that when the cavity is injected with serum and then pressurized, the serum is permeated into the wire-wound filter element, the larger particles and impurities in the filtered serum are captured in the wire-wound filter element, the preliminarily filtered serum enters the sleeve inside the sleeve plug and is subjected to secondary filtration by the filter membrane, bacteria and other microorganisms in the serum are removed, the blood serum pretreatment filter device can completely filter the serum, and the filter membrane is prevented from being blocked by the larger particles and impurities in the serum to affect the filtration effect.

[0013] 2. The blood serum pretreatment filter device is provided with a stainless steel framework inserted on the top of the sleeve plug and a sleeve threadedly connected between the sleeve plug and the serum discharge pipe, so that the device can be easily disassembled and replaced, and the operation steps are simple and efficient. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0015] Figure 2 It is a schematic diagram of the overall structure of the utility model; Figure 1 It is an enlarged schematic diagram of the structure at A in the utility model;

[0016] Figure 3The cavity structure split state schematic view of the utility model;

[0017] Figure 4 The cavity structure part section schematic view of the utility model;

[0018] Figure 5 The line winding filter core structure part section schematic view of the utility model.

[0019] In the figure: 1, cavity;2, pressurizing pipe;3, support column;4, serum discharge pipe;5, base;6, bottom plate;7, clamping block;8, feeding pipe;9, upper cover;10, limiting block;11, support;12, cross bar;13, bottom column;14, upper column;15, connecting column;16, sleeve;17, filter membrane;18, metal cover;19, auxiliary handle;20, sleeve plug;21, rubber ring;22, stainless steel framework;23, line winding filter core. DETAILED DESCRIPTION

[0020] The technical scheme in the embodiments of the utility model will be described clearly and completely below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0021] In the description of the utility model, it should be explained that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the utility model and simplifying the description, and is not indicative or suggestive of the device or element indicated must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model. In addition, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicative or suggestive of relative importance.

[0022] As Figures 1 to 5As shown, the serum pretreatment filter device of the embodiment includes a cavity 1, a top of the cavity 1 is threadedly connected with an upper cover 9, the upper cover 9 seals the top of the cavity 1, and the inside of the cavity 1 is in a sealed state when the serum pretreatment filter is used, so as to facilitate pressurization, a sleeve plug 20 is arranged at an intermediate position inside the cavity 1, a stainless steel framework 22 is sleeved on the top outer surface of the sleeve plug 20, a wire-wound filter element 23 is arranged on the outer surface of the stainless steel framework 22, a plurality of holes are arranged on the outer surface of the stainless steel framework 22, the stainless steel framework 22 is matched with the sleeve plug 20, the stainless steel framework 22 is sleeved on the outer surface of the sleeve plug 20, and the wire-wound filter element 23 is fixed inside the cavity 1, when the cavity 1 is injected with the serum to be filtered, the serum will pass through the wire-wound filter element 23, the wire-wound filter element 23 is composed of a filtering material, and can capture larger particles and impurities in the serum to be filtered inside the wire-wound filter element 23, the filtered serum enters the inside of the stainless steel framework 22 through the holes on the outer surface of the stainless steel framework 22, and then falls into the inside of the sleeve plug 20, an upper end of the upper cover 9 is provided with a feeding pipe 8, a bottom of the feeding pipe 8 extends to one side of the wire-wound filter element 23 inside the cavity 1, the feeding pipe 8 can be connected with a hose to put the serum to be filtered into the cavity 1, the top of the feeding pipe 8 is provided with a clamping block 7, one side of the cavity 1 is provided with a pressurizing pipe 2, the pressurizing pipe 2 can be connected with a manual pressurizing device or a pressurizing machine, after the serum is injected, the clamping block 7 is installed on the top of the feeding pipe 8, the feeding pipe 8 is sealed, and then air is injected into the cavity 1 through the pressurizing pipe 2 to pressurize the serum, so that the serum can be infiltrated and filtered into the wire-wound filter element 23, the filtering efficiency is improved, a bottom end of the cavity 1 is provided with a bottom plate 6, a bottom of the sleeve plug 20 extends to the bottom of the bottom plate 6 through the bottom plate 6 of the cavity 1, a sleeve pipe 16 is threadedly connected with an extension end of the sleeve plug 20, a filter membrane 17 is arranged in the inside of the sleeve pipe 16, a serum discharge pipe 4 is threadedly connected with a bottom of the sleeve pipe 16, the filter membrane 17 is a 0.2 μm cellulose acetate filter paper, which can effectively remove bacteria and other microorganisms in the serum, after the serum filtered by the wire-wound filter element 23 enters the inside of the sleeve pipe 16 through the sleeve plug 20, the serum is secondarily filtered by the filter membrane 17, and then is discharged into a storage device through the serum discharge pipe 4, the sleeve pipe 16 is threadedly connected with the sleeve plug 20 and the serum discharge pipe 4 respectively, and is convenient to disassemble and replace.

[0023] Specifically, the top of the clamping block 7 is provided with an upper column 14, which is an L-shaped part. The bottom of the upper column 14 is sleeved with a bottom column 13. The bottom end of the bottom column 13 is provided with a horizontal rod 12. One end of the horizontal rod 12 is hingedly installed with a support 11. One end of the support 11 is connected with the outer surface of the feeding pipe 8 through a connecting column 15. The bottom of the clamping block 7 matches the feeding pipe 8. When the clamping block 7 is clamped on the top of the feeding pipe 8, the inside of the cavity 1 is in a sealed state. When the clamping block 7 is pulled out and the hose is connected on the top of the feeding pipe 8 to transport blood, the bottom of the upper column 14 extends upward from the inside of the bottom column 13. Then, the clamping block 7 is rotated to leave the top of the feeding pipe 8 through the support 11, which is convenient for connecting the hose on the top of the feeding pipe 8.

[0024] Further, the connecting column 15 is provided with a limiting block 10 at one side edge close to the horizontal rod 12. When the clamping block 7 is rotated to be directly above the feeding pipe 8, the horizontal rod 12 is blocked by the limiting block 10 and cannot continue to rotate, which is convenient for installing the clamping block 7 on the top of the feeding pipe 8 and ensuring the sealing of the cavity 1.

[0025] Further, the bottom end of the bottom plate 6 is provided with a support column 3 at each corner position. The bottom ends of the four support columns 3 are commonly connected with a base 5. The support column 3 and the base 5 are used in cooperation, so that the serum pre-treatment filtering device can be stably placed on a plane. The support column 3 lifts the bottom plate 6, so that the bottom of the serum discharge pipe 4 has a certain height, which is convenient for placing the serum storage device below the serum discharge pipe 4.

[0026] Further, the outer surface of the plug 20 inside the cavity 1 is provided with two rubber rings 21. The top of the plug 20 matches a stainless steel framework 22. When the stainless steel is inserted into the inside of the plug 20, the rubber ring 21 adheres to the inner wall of the stainless steel framework 22, which reduces the gap and improves the sealing performance.

[0027] Further, the top outer surface of the wire-wound filter element 23 is provided with a metal cover 18. The top end of the metal cover 18 is provided with an auxiliary handle 19. The metal cover 18 protects the top of the wire-wound filter element 23, which avoids the blood injected into the inside of the cavity 1 from sticking to the top of the wire-wound filter element 23 and affecting the filtration. When the wire-wound filter element 23 is disassembled, the wire-wound filter element 23 can be pulled out through the auxiliary handle 19, which is simple in steps and convenient to operate.

[0028] The use method of the embodiment is as follows: when the filter device for serum pretreatment is used, the clamping block 7 is pulled out, the bottom of the upper column 14 extends upward from the inside of the bottom column 13, then the clamping block 7 is rotated to be separated from the top of the feeding pipe 8 through the support 11, the soft tube is connected to the top of the feeding pipe 8 to convey blood, after the serum injection is completed, the clamping block 7 is installed on the top of the feeding pipe 8 to seal the feeding pipe 8, then air is injected into the cavity 1 through the pressurizing pipe 2 to pressurize the serum, so that the serum can penetrate into the inside of the wire-wound filter element 23 to improve the filtering efficiency, the serum in the cavity 1 can pass through the wire-wound filter element 23, the wire-wound filter element 23 is composed of a group of filter materials, and can capture larger particles and impurities in the serum to be filtered in the inside of the wire-wound filter element 23, the filtered serum enters the inside of the stainless steel framework 22 through the holes on the outer surface of the stainless steel framework 22, and then falls into the inside of the sleeve plug 20, after the serum filtered by the wire-wound filter element 23 enters the inside of the sleeve pipe 16 through the sleeve plug 20, the serum is secondarily filtered by the filter membrane 17, and then is discharged to a storage device through the serum discharge pipe 4, the sleeve pipe 16 is threadedly connected with the sleeve plug 20 and the serum discharge pipe 4, so that the sleeve pipe 16 can be conveniently disassembled and replaced.

[0029] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and not for limiting the present application, although the present application has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A filtering device for the pre-treatment of serum comprising a chamber (1), characterized in that: The top of the cavity (1) is threadedly connected with an upper cover (9), a sleeve plug (20) is arranged at the middle position of the inner part of the cavity (1), the top outer surface of the sleeve plug (20) is sleeved with a stainless steel framework (22), the outer surface of the stainless steel framework (22) is provided with a wire-wound filter element (23), the top of the upper cover (9) is provided with a feeding pipe (8), the bottom of the feeding pipe (8) extends to one side of the wire-wound filter element (23) inside the cavity (1), the top of the feeding pipe (8) is provided with a clamping block (7), one side of the cavity (1) is provided with a pressurizing pipe (2), the bottom end of the cavity (1) is provided with a bottom plate (6), the bottom of the sleeve plug (20) extends through the bottom plate (6) of the cavity (1) to the bottom of the bottom plate (6), the extended end of the sleeve plug (20) is threadedly connected with a sleeve pipe (16), the inside of the sleeve pipe (16) is provided with a filter membrane (17), the bottom of the sleeve pipe (16) is threadedly connected with a serum discharge pipe (4).

2. The filter device for serum pretreatment according to claim 1, characterized in that: The top of the clamping block (7) is provided with an upper column (14), the upper column (14) is an L-shaped part, the bottom of the upper column (14) is sleeved with a bottom column (13), the bottom end of the bottom column (13) is provided with a cross rod (12), one end of the cross rod (12) is hingedly installed with a support (11), one end of the support (11) and the outer surface of the feeding pipe (8) are jointly connected with a connecting column (15).

3. The filter device for serum pretreatment according to claim 2, characterized in that: The connecting column (15) is provided with a limiting block (10) at the position close to the cross rod (12) at one side edge.

4. The filter device for serum pretreatment according to claim 1, characterized in that: The bottom end of the bottom plate (6) is provided with a supporting column (3) at the four corner positions, the bottom ends of the four supporting columns (3) are jointly connected with a base (5).

5. The filter device for serum pretreatment according to claim 1, characterized in that: The outer surface of the sleeve plug (20) inside the cavity (1) is provided with two rubber rings (21).

6. The filter device for serum pretreatment according to claim 1, characterized in that: The top outer surface of the wire-wound filter element (23) is provided with a metal cover (18), the top end of the metal cover (18) is provided with an auxiliary handle (19).

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