Polypeptide treatment device for chemical continuous flow reaction
By designing a peptide processing device that is easy to install and uses shaking for mixing, the problems of inconvenient reagent addition and insufficient mixing in existing devices have been solved, thereby improving reaction efficiency.
Patent Information
- Application Number
- CN202520365876.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-04
- Publication Date
- 2026-01-30
- Estimated Expiration
- 2035-03-04
AI Technical Summary
Existing peptide processing devices are not convenient for adding chemical reagents at any time in continuous chemical reactions, and are not convenient for shaking and mixing, resulting in low reaction efficiency.
A device comprising a housing, a storage bottle, a reaction bottle, a peristaltic pump, and an eccentric wheel was designed. The reaction bottle is conveniently installed and shaken for mixing through a clamping plate, a damper, and a drive motor. The peristaltic pump is used to adjust the amount of reagent added, and the eccentric wheel drives the support frame to shake to promote mixing.
This allows for convenient addition of chemical reagents and thorough mixing and reaction, improving the effectiveness and efficiency of the equipment.
Smart Images

Figure CN223846934U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to polypeptide processing technical field, concretely is a kind of polypeptide processing device of chemical continuous flow reaction. BACKGROUND
[0002] Polypeptide is the biomolecule that by multiple amino acids is connected by peptide bond, plays an important role in organism, such as as hormone, enzyme or antibody etc. In laboratory, polypeptide processing is an important component of biochemical research, such as;
[0003] The authorized announcement No. CN215842385U provides a kind of biological polypeptide production pretreatment device, including collection tank and fixed in the water supply mechanism of collection tank inside top, the bottom of the collection tank is equipped with liquid outlet pipe, and the side of collection tank is equipped with inlet pipe, the inlet pipe is fixedly connected with airflow dispersion component outside the one end of the inside of inlet pipe that extends into collection tank, the inside of one end of the liquid outlet pipe connected with collection tank bottom is equipped with pressure switch component, the pressure switch component includes arc plate, and arc plate is fixed in the inside edge of liquid outlet pipe port, the side of arc plate is movably connected with switch plate, and the bottom end of arc plate is equipped with torsion spring.The utility model, by the pressure switch component of being set, water mist can be prevented in a certain time from entering liquid outlet pipe, improve the absorption rate of water mist to gas;By the airflow dispersion component of being set, the dispersion effect of gas into collection tank can be improved.
[0004] In combination with prior art scheme and actual production and processing, the polypeptide processing device still has the following defects at present: inconvenient to add chemical reagent for chemical continuous flow reaction in the process, so that the device is not easy to add different chemical reagents according to the reaction condition, reduce the use effect of device, at the same time, inconvenient to shock mix the chemical reagent being reacted in the process of device use, so that chemical reagent is not easy to fully mixed reaction in the process of reaction, reduce the reaction efficiency of device, therefore, the utility model provides a kind of polypeptide processing device of chemical continuous flow reaction to solve the problems raised in the above. UTILITY MODEL CONTENTS
[0005] The utility model aims at providing a kind of polypeptide processing device of chemical continuous flow reaction to solve the problems raised in the above background art in the process, inconvenient to add chemical reagent for chemical continuous flow reaction, so that the device is not easy to add different chemical reagents according to the reaction condition, reduce the use effect of device, at the same time, inconvenient to shock mix the chemical reagent being reacted in the process of device use, so that chemical reagent is not easy to fully mixed reaction in the process of reaction, reduce the reaction efficiency of device.
[0006] To achieve the above object, the utility model provides the following technical scheme: A kind of polypeptide processing device of chemical continuous flow reaction, comprising: machine body shell, and the liquid storage bottle of machine body shell outside setting, still including:
[0007] Machine cover, it is installed in the upside of machine body shell, and the inside of machine body shell is provided with first support frame, the inside of first support frame is provided with first damper, and the inside of first damper is provided with support rod, the outside of support rod is provided with first guide block, and the inside of support rod is provided with second support frame, the upside of second support frame is provided with limit component, and the inside of limit component is provided with reaction bottle, the lower end of reaction bottle is provided with connecting port, and the lower end of connecting port is connected with corrugated hose, the lower end of corrugated hose is provided with infusion pipeline, and the outside of infusion pipeline is provided with first peristaltic pump, the lower end of liquid storage bottle is provided with guide rod, and the inside of liquid storage bottle is provided with observation plate, the lower end of infusion pipeline is provided with electromagnetic valve, and the lower end of electromagnetic valve is provided with second peristaltic pump.
[0008] In a possible implementation, the limit component includes a clamping plate mounted on the upper side of the second support frame, the inner side of the clamping plate is provided with an anti-slip pad, and the outer side of the clamping plate is provided with a second damper, and the lower end of the clamping plate is provided with a second guide block.
[0009] In a possible implementation, the clamping plate is symmetrically arranged about the central axis of the second support frame, and the anti-slip pad is arranged on opposite sides of the clamping plate.
[0010] In a possible implementation, the second guide block is slidably arranged opposite to the second support frame, and the longitudinal section of the second guide block is in a "T" shape structure.
[0011] In a possible implementation, the support rod is slidably arranged opposite to the first guide block and the first support frame, and the first guide block is symmetrically arranged about the central axis of the support rod.
[0012] In a possible implementation, the liquid storage bottle is slidably arranged opposite to the guide rod, and the liquid storage bottle is arranged opposite to the machine body shell.
[0013] In a possible implementation, the reaction bottle is arranged opposite to the connecting port.
[0014] In a possible implementation, the lower end of the second support frame is provided with an eccentric wheel, and the front end of the eccentric wheel is provided with a driving motor.
[0015] In a possible implementation, the longitudinal section of the eccentric wheel is in an elliptical structure, and the eccentric wheel is rotatably arranged opposite to the machine body shell.
[0016] Compared with the prior art, the polypeptide processing device for chemical continuous flow reaction has the advantages that: the chemical reagent can be added at any time for chemical continuous flow reaction in the process, different chemical reagents can be added according to the reaction condition, the use effect of the device is improved, the chemical reagent being reacted can be shaken and mixed in the process of use of the device, the chemical reagent can be fully mixed and reacted in the process of reaction, the reaction efficiency of the device is improved, and the device has better use effect, and the specific contents are shown as follows.
[0017] 1. The second damper cooperates with the second guide block to push the clamping plate to displace inward, so that the clamping plate cooperates with the non-slip pad to clamp the reaction bottle in the middle of the second support frame, convenient for the operator to conveniently clamp and dismount the reaction bottle, and improve the maintenance and cleaning efficiency of the device.
[0018] 2. The body shell cooperates with the guide rod to fix the liquid storage bottle outside the body shell, so that the first peristaltic pump pours the chemical reagent stored in the liquid storage bottle into the reaction bottle through the infusion pipeline for chemical reaction, which is convenient for the device to adjust the reagent adding amount of the device according to different reaction needs, and improves the reaction effect of the device.
[0019] 3. The driving motor cooperates with the eccentric wheel to push the second support frame to oscillate and displace left and right in the body shell along the support rod and the first guide block, so that the chemical reagent in the reaction bottle can be fully mixed and reacted, and the processing effect of the device is improved. BRIEF DESCRIPTION OF DRAWINGS
[0020] Figure 1 It is a front view cross-sectional structure schematic view of the utility model;
[0021] Figure 2 It is a side view cross-sectional structure schematic view of the utility model;
[0022] Figure 3 It is a top view cross-sectional structure schematic view of the utility model;
[0023] Figure 4 It is a front view cross-sectional structure schematic view of the utility model Figure 1 It is an enlarged structure schematic view of A in the utility model;
[0024] Figure 5 It is a clamping plate and second guide block connection integral structure schematic view of the utility model.
[0025] In the figure: 1, the machine body shell; 2, the machine cover; 3, the first support frame; 4, the first damper; 5, the support rod; 6, the first guide block; 7, the second support frame; 8, the limiting assembly; 801, the clamping plate; 802, the non-slip pad; 803, the second damper; 804, the second guide block; 9, the reaction bottle; 10, the eccentric wheel; 11, the driving motor; 12, the connecting port; 13, the corrugated hose; 14, the infusion pipeline; 15, the first peristaltic pump; 16, the liquid storage bottle; 17, the guide rod; 18, the observation plate; 19, the electromagnetic valve; 20, the second peristaltic pump. DETAILED DESCRIPTION
[0026] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0027] Please refer to Figures 1-5 The utility model provides a kind of technical scheme: a kind of polypeptide processing device of chemical continuous flow reaction, comprising: machine body shell 1, and the liquid storage bottle 16 being arranged outside machine body shell 1, further comprising:
[0028] Machine cover 2 is installed in the upper side of machine body shell 1, and the inside of machine body shell 1 is provided with first support frame 3, the inside of first support frame 3 is provided with first damper 4, and the inside of first damper 4 is provided with support rod 5, the outside of support rod 5 is provided with first guide block 6, and the inside of support rod 5 is provided with second support frame 7, the upper side of second support frame 7 is provided with limiting assembly 8, and the inside of limiting assembly 8 is provided with reaction bottle 9, the lower end of reaction bottle 9 is provided with connecting port 12, and the lower end of connecting port 12 is connected with corrugated hose 13, the lower end of corrugated hose 13 is provided with infusion pipeline 14, and the outside of infusion pipeline 14 is provided with first peristaltic pump 15, the lower end of liquid storage bottle 16 is provided with guide rod 17, and the inside of liquid storage bottle 16 is provided with observation plate 18, the lower end of infusion pipeline 14 is provided with electromagnetic valve 19, and the lower end of electromagnetic valve 19 is provided with second peristaltic pump 20, to constitute complete polypeptide processing device.
[0029] As Figure 1 , Figure 4 and Figure 5As shown, the limiting assembly 8 comprises a clamping plate 801 mounted on the upper side of the second support frame 7, the inner side of the clamping plate 801 is provided with a non-slip pad 802, and the outer side of the clamping plate 801 is provided with a second damper 803, and the lower end of the clamping plate 801 is provided with a second guide block 804, the clamping plate 801 is symmetrically arranged about the central axis of the second support frame 7, the non-slip pad 802 is arranged opposite to the clamping plate 801, the second guide block 804 is slidably arranged opposite to the second support frame 7, and the longitudinal section of the second guide block 804 is in the shape of a "T" letter. During use of the device, the clamping plate 801 is pulled outward, so that the clamping plate 801 is displaced outward along the second guide block 804 to press the second damper 803, facilitating the operator to install the reaction bottle 9 on the upper side of the connecting port 12, and at the same time, the pulling of the clamping plate 801 is released, so that the second damper 803 pushes the clamping plate 801 to reset inward along the second guide block 804 to fix the reaction bottle 9 on the inner side of the second support frame 7, facilitating the operator to conveniently clamp and dismount the reaction bottle 9, and improving the maintenance and cleaning efficiency of the device.
[0030] As shown in Figure 1 , Figure 2 and Figure 3 , the liquid storage bottle 16 is slidably arranged opposite to the guide rod 17, and the liquid storage bottle 16 is arranged opposite to the machine body shell 1, and the reaction bottle 9 is arranged opposite to the connecting port 12. During use of the device, the required chemical reagent is poured into the inside of the liquid storage bottle 16, and at the same time, the liquid storage bottle 16 is installed on the outside of the machine body shell 1 along the guide rod 17, so that the first peristaltic pump 15 pours the chemical reagent stored in the inside of the liquid storage bottle 16 into the inside of the reaction bottle 9 through the infusion pipeline 14 to perform chemical reaction, facilitating the device to adjust the amount of reagent added by the device according to different reaction needs, and improving the reaction effect of the device.
[0031] As shown in Figure 1 , Figure 2 and Figure 3 , the lower end of the second support frame 7 is provided with an eccentric wheel 10, and the front end of the eccentric wheel 10 is provided with a driving motor 11. The longitudinal section of the eccentric wheel 10 is in the shape of an ellipse, and the eccentric wheel 10 is rotatably arranged opposite to the machine body shell 1. The support rod 5 is slidably arranged opposite to the first guide block 6 and the first support frame 3, and the first guide block 6 is symmetrically arranged about the central axis of the support rod 5. During use of the device, the driving motor 11 drives the eccentric wheel 10 to rotate in the inside of the machine body shell 1, so that the eccentric wheel 10 pushes the second support frame 7 to oscillate and displace left and right in the inside of the machine body shell 1 along the support rod 5 and the first guide block 6, facilitating the chemical reagent in the inside of the reaction bottle 9 to be fully mixed and reacted, and improving the processing effect of the device.
[0032] The standard parts used in the utility model can be purchased from the market, the special-shaped parts can be ordered according to the description and the drawings, the specific connection mode of each part adopts the conventional means such as bolts, rivets and welding in the prior art, the machinery, parts and equipment adopt conventional models in the prior art, the conventional connection mode in the prior art is adopted for circuit connection, and details are not described herein, and the contents not described in detail in the description belong to the prior art known by the person skilled in the art.
[0033] Although the utility model is described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or make equivalent replacement to part of the technical features, and any modification, equivalent replacement, improvement and the like within the spirit and principle of the utility model should be included in the protection scope of the utility model.
Claims
1. A polypeptide processing device for chemical continuous flow reactions, comprising: The utility model provides a portable reaction bottle, and the machine body shell (1) and the liquid storage bottle (16) outside the machine body shell (1) are characterized by further comprising: The machine cover (2) is installed on the upside of the machine body shell (1), and the inside of the machine body shell (1) is provided with the first support frame (3), the inside of the first support frame (3) is provided with the first damper (4), the inside of the first damper (4) is provided with the support rod (5), the outside of the support rod (5) is provided with the first guide block (6), the inside of the support rod (5) is provided with the second support frame (7), the upside of the second support frame (7) is provided with the limiting assembly (8), the inside of the limiting assembly (8) is provided with the reaction bottle (9), the lower end of the reaction bottle (9) is provided with the connecting port (12), the lower end of the connecting port (12) is connected with the corrugated hose (13), the lower end of the corrugated hose (13) is provided with the infusion pipeline (14), the outside of the infusion pipeline (14) is provided with the first peristaltic pump (15), the lower end of the liquid storage bottle (16) is provided with the guide rod (17), the inside of the liquid storage bottle (16) is provided with the observation plate (18), the lower end of the infusion pipeline (14) is provided with the electromagnetic valve (19), and the lower end of the electromagnetic valve (19) is provided with the second peristaltic pump (20).
2. A polypeptide treatment device for chemical continuous flow reactions according to claim 1, characterized in that: The limiting assembly (8) comprises the clamping plate (801) installed on the upside of the second support frame (7), the inside of the clamping plate (801) is provided with the antiskid pad (802), the outside of the clamping plate (801) is provided with the second damper (803), and the lower end of the clamping plate (801) is provided with the second guide block (804).
3. A polypeptide treatment device for chemical continuous flow reactions according to claim 2, wherein: The clamping plate (801) is symmetrically arranged about the central axis of the second support frame (7), and the antiskid pad (802) is arranged opposite the clamping plate (801).
4. The polypeptide treatment device for chemical continuous flow reactions according to claim 2, characterized in that: The second guide block (804) is slidably arranged opposite the second support frame (7), and the longitudinal section of the second guide block (804) is in the shape of a "T".
5. The polypeptide treatment device for chemical continuous flow reactions according to claim 1, characterized in that: The support rod (5) is slidably arranged opposite the first guide block (6) and the first support frame (3), and the first guide block (6) is symmetrically arranged about the central axis of the support rod (5).
6. The polypeptide treatment device for chemical continuous flow reactions according to claim 1, characterized in that: The liquid storage bottle (16) is slidably arranged opposite the guide rod (17), and the liquid storage bottle (16) is arranged opposite the machine body shell (1).
7. The polypeptide treatment device for chemical continuous flow reactions according to claim 1, characterized in that: The reaction bottle (9) is arranged opposite the connecting port (12).
8. The polypeptide treatment device for chemical continuous flow reactions according to claim 1, characterized in that: The lower end of the second support frame (7) is provided with the eccentric wheel (10), and the front end of the eccentric wheel (10) is provided with the driving motor (11).
9. A polypeptide treatment device for chemical continuous flow reactions according to claim 8, wherein: The longitudinal section of the eccentric wheel (10) is in the shape of an ellipse, and the eccentric wheel (10) is rotatably arranged opposite the machine body shell (1).
Citation Information
Patent Citations
Biological polypeptide production pretreatment device
CN215842385U