Adapter, rotor assembly and centrifuge

Abstract

The utility model provides an adapter, a rotor assembly and a centrifugal machine. Wherein the adapter is provided with a plurality of assembling holes, the assembling holes are used for assembling the centrifugal tubes, and the inner surface of at least one of the assembling holes is connected with the outer surface of the side wall of the adapter, so that when the centrifugal tubes are assembled in the assembling holes, part of the side wall of each centrifugal tube is exposed on the outer side of the side wall of the adapter. Compared with the mode that all the assembling holes are located in the adapter, part (at least one) of the assembling holes are moved outwards to be connected with the side wall, the internal available space can be increased to a certain degree, and more centrifugal tubes can be contained by changing the layout of the assembling holes located in the adapter.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of centrifuge equipment, in particular to an adapter, a rotor assembly and a centrifuge. BACKGROUND

[0002] Centrifuge is a commonly used device in scientific research process, which mainly utilizes the centrifugal force generated by the rotor assembly to separate different density and different particle size substances in the suspension or emulsion.

[0003] Generally, centrifuge needs to be matched with centrifuge tube or centrifuge bottle for use, but centrifuge tubes or centrifuge bottles of different capacities are different in size, and an adapter is needed to assist in fixing during centrifugation. How to make the adapter fix as many centrifuge tubes as possible is a problem to be solved. SUMMARY

[0004] In order to solve the above problems, the present application provides an adapter, which has a plurality of assembly holes for assembling centrifuge tubes, wherein the inner surface of at least one of the assembly holes is connected with the outer surface of the side wall of the adapter, so that when the centrifuge tube is assembled with the assembly hole, part of the side wall of the centrifuge tube is exposed outside the side wall of the adapter.

[0005] Compared with all assembly holes located inside the adapter, moving part (at least one) of the assembly holes to the side wall can increase the available space inside to a certain extent, and more centrifuge tubes can be accommodated by changing the layout of the assembly holes inside.

[0006] The present application also provides a rotor assembly, which comprises a receiving groove, and the receiving groove is assembled with the above-mentioned adapter.

[0007] The present application also provides a centrifuge, which comprises a main machine and the above-mentioned rotor assembly, and the main machine is used for controlling the rotation of the rotor assembly. BRIEF DESCRIPTION OF DRAWINGS

[0008] Figure 1 It is a structural schematic diagram of centrifuge main machine;

[0009] Figure 2 It is a schematic diagram of working principle of horizontal rotor;

[0010] Figure 3 It is a schematic diagram of working principle of angle rotor;

[0011] Figure 4 It is a schematic diagram of 400 milliliter centrifuge bottle;

[0012] Figure 5 It is a schematic diagram of 15 milliliter centrifuge tube;

[0013] Figure 6 It is a structural schematic diagram of adapter for 15 milliliter centrifuge tube;

[0014] Figure 7 Top view of the adapter for 15ml centrifuge tube;

[0015] Figure 8 Schematic view of the structure of the adapter for 50ml centrifuge tube;

[0016] Figure 9 Top view of the adapter for 50ml centrifuge tube;

[0017] Figure 10 Schematic view of the interface of different components after centrifugation for centrifuge tube in inclined posture;

[0018] Figure 11 Schematic view of the interface of different components after centrifugation for centrifuge tube in horizontal posture.

[0019] BRIEF DESCRIPTION OF DRAWINGS

[0020] centrifuge 1,

[0021] main machine 10, rotating shaft 100,

[0022] rotor assembly 20, horizontal rotor 20a, angular rotor 20b, accommodating groove 200,

[0023] adapter 25, assembly hole 250, side wall 251, notch 252, end face 253, hand holding part 254, positioning part 255. DETAILED DESCRIPTION

[0024] The present application will be further described below in conjunction with the accompanying drawings and some embodiments. The following embodiments are mainly used to exemplarily illustrate the technical solutions of the present application, and thus cannot limit the protection scope of the present application.

[0025] Unless otherwise defined, the technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present application belongs; the terms used herein are mainly for the purpose of describing specific embodiments, and are not intended to limit the present application; the terms "include", "have", "contain" and other synonymous words with the same or similar meanings in the specification and claims of the present application and the above description of drawings are intended to cover non-exclusive inclusion.

[0026] In the description of the embodiments of the present application, the technical terms "first", "second" and the like mainly play the role of facilitating the distinction between different objects, and cannot be understood as explicitly or implicitly indicating relative importance or implicitly indicating the number, specific order or primary and secondary relationship of the indicated technical features. In the description of the embodiments of the present application, the meaning of "a plurality of" is two or more, unless otherwise specifically limited.

[0027] In this document, the terms "specific feature," "structure" or "characteristic" that is described in any one embodiment can be included in at least one embodiment or in a combination of at least two embodiments of the present disclosure. It can be understood by those skilled in the art that the embodiments described herein can be combined with other embodiments herein or other embodiments outside herein.

[0028] In the description of the embodiments of the present application, the technical terms used to indicate the position or positional relationship, such as "center", "lengthwise", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like, are mainly used to facilitate the description of the embodiments of the present application and simplify the description, and are not considered to be the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present application.

[0029] In various embodiments of the present application, unless otherwise explicitly specified and limited, the technical terms "set", "mount", "assemble", "connect", "connect", "fix" and the like should be understood in a broad sense. For example, it can include fixed connection, detachable connection or integral molding; it can include at least one of mechanical connection and electrical connection; it can include direct connection or indirect connection through intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of the present application according to the specific circumstances.

[0030] The centrifuge can be applied to the field of life science such as genomics to nanotechnology, and can separate, concentrate, extract and prepare samples under the action of centrifugal force by using the sedimentation coefficient, buoyancy and density difference of the centrifuged sample material, for example, serum / blood cell separation, protein purification, or nucleic acid sample purification, etc.

[0031] Referring to Figure 1 , the centrifuge 1 can include a host 10 and a rotor assembly 20. The host 10 is used to control the rotation of the rotor assembly 20. The host 10 can include a control module and a motor coupled to the control module. The rotor assembly 20 can be connected with the rotating shaft 100 of the motor and rotate under the driving of the rotating shaft 100.

[0032] The rotor assembly 20 can be divided into horizontal rotor 20a and angle rotor 20b according to different types. Most of the rotor assemblies 20 of the centrifuges on the market can be disassembled, and generally can be used with different types and different specifications of rotor assemblies 20. In Figure 1 , the horizontal rotor 20a and the angle rotor 20b can be used with the host 10.

[0033] Referring toFigure 2 The horizontal rotor 20a is also called swing-out rotor, swing-down rotor. The centrifuge tubes are placed in the swing-baskets, which are hung on the horizontal rotor 20a in a symmetrical manner. When the rotor is rotated, the swing-baskets are swung from the vertical position to the horizontal position by the centrifugal force, so it is also called swing-out rotor and swing-down rotor.

[0034] Referring to Figure 3 The angle rotor 20b is short for fixed-angle rotor. The angle θ between the centrifuge tube containing the solution and the rotation shaft 100 is formed during the manufacture of the rotor and can never be changed. The angle range is generally between 14° and 40°. During the centrifugation, the centrifuge tube is fixed, the sample is reoriented, the smaller the angle between the centrifuge tube and the rotation shaft 100, the greater the reorientation, and the higher the centrifugation efficiency.

[0035] Both the angle rotor 20b and the horizontal rotor 20a include a receiving groove 200. The receiving groove 200 can be fitted with an adapter 25. On the horizontal rotor 20a, the receiving groove 200 is usually formed on the swing-baskets.

[0036] In some devices, the receiving groove 200 can accommodate a 400-milliliter centrifuge bottle. Referring to Figure 4 The outer diameter of the 400-milliliter centrifuge bottle is 80 millimeters. Therefore, the inner diameter of the receiving groove 200 is usually equal to or slightly larger than 80 millimeters to stably fix the 400-milliliter centrifuge bottle. In this case, the outer diameter of the adapter 25 is 80 millimeters. In this way, a 100-milliliter or 15-milliliter centrifuge tube can also be stably fixed in the above-mentioned centrifuge bottle through the adapter 25.

[0037] If the receiving groove 200 of this specification is used to centrifuge a small-capacity centrifuge tube, such as the 15-milliliter centrifuge tube in Figure 5 , or a 50-milliliter or 100-milliliter centrifuge tube, the adapter 25 needs to be used.

[0038] Referring to Figure 6 , Figure 7 , Figure 8 and Figure 9 The adapter 25 can have a plurality of fitting holes 250 for fitting the centrifuge tube. Among them, the inner surface of at least one of the fitting holes 250 (for example, the fitting hole 250a in Figure 6 ) is connected to the outer surface of the side wall 251 of the adapter 25, so that when the centrifuge tube is fitted with the fitting hole 250a, part of the side wall 251 of the centrifuge tube is exposed outside the side wall 251 of the adapter 25.

[0039] By moving some of the assembly holes 250 (at least one, for example, assembly hole 250a) to the side wall 251, the available space inside the adapter 25 can be increased to some extent, and more centrifuge tubes can be accommodated by changing the layout of the assembly holes 250 inside the adapter 25. See Figure 7 where the dashed part represents the arrangement area of the caps when the 15ml centrifuge tubes are assembled. In this way, nine assembly holes 250 can be provided in the adapter 25 with a diameter of 80mm, and one assembly hole 250 is added compared with the conventional adapter 25.

[0040] The area where the inner surface of the assembly hole 250a and the outer surface of the side wall 251 of the adapter 25 are connected forms a gap 252, and the average width of the gap 252 is less than the average value of the inner diameter of the assembly hole 250. That is, the average width of the gap 252 is less than the outer diameter of the centrifuge tube. In this way, the centrifuge tube can be prevented from falling off from the gap 252.

[0041] See Figure 7 and Figure 9 The distance between the centers of at least two assembly holes 250 is between 22.3mm and 35mm. The diameter of the 15mm centrifuge tube is about 17mm, and the diameter of the cap is about 22.3mm. Therefore, the distance between the assembly holes 250 should not be less than 22.3mm, so that the caps do not interfere with each other when the centrifuge tubes are assembled. Further, the distance between the centers of two assembly holes 250 can be 22.5mm, so that a certain margin is left to reduce the influence of manufacturing errors of the cap or the adapter 25. Similarly, the distance between the centers of two assembly holes 250 can be 34.7mm, so that the assembly holes 250 can be assembled with 50ml centrifuge tubes.

[0042] At least two of the plurality of assembly holes 250 are arranged in parallel. In this way, the processing of the adapter 25 can be facilitated. The material of the adapter 25 can be PA, POM, PP or other plastic materials with good toughness and strength. In this way, the adapter 25 can be integrally formed by injection molding.

[0043] The axial direction of the plurality of assembly holes 250 is parallel to the axial direction of the adapter 25. In this way, when the adapter 25 is used with the horizontal rotor 20a, the adapter 25 will change from a vertical state to a horizontal state during centrifugation. See Figure 10 and Figure 11 Since the axial direction of the assembly holes 250 is parallel to the axial direction of the adapter 25, when the adapter 25 is in the horizontal state, the centrifuge tubes in the assembly holes 250 are also in the horizontal state. During centrifugation, the components with higher density will move to the end farther from the rotation shaft 100, i.e., to the bottom of the centrifuge tube.

[0044] In addition, seeFigure 10 and Figure 11 When the centrifuge tube is set in a slanted way during centrifugation (the axial direction of the centrifuge tube is not perpendicular to the vertical axis), the interface of different components (parallel to the vertical axis) is also slanted to the axial direction of the centrifuge tube. Therefore, when the user takes out the centrifuge tube, the interface of different components is also slanted to the axial direction of the centrifuge tube. Such an interface is not conducive to subsequent separation and sampling.

[0045] However, when the assembly hole 250 is parallel to the axial direction of the adapter 25, and is used with the horizontal rotor 20a. During centrifugation, the interface of different components is perpendicular to the axial direction of the centrifuge tube. Such an interface is conducive to subsequent separation and sampling.

[0046] In addition, the adapter can have a hand-held portion 254 arranged on the end face 253. The hand-held portion 254 is arranged away from the assembly hole. The main function of the hand-held portion 254 is that after centrifugation, the experimenter can hold the hand-held portion 254 to take out the adapter and the centrifuge tube from the accommodation groove. The arrangement position of the hand-held portion 254 can be determined according to the situation, for example, it can be arranged in the central region of the end face 253, or it can be arranged in the region close to the boundary of the end face 253. The number of hand-held portions 254 can be two, and they can be in the shape of a strip. The hand-held portion 254 can be integrally formed with the adapter, which can reduce the production process, improve the production efficiency, and reduce the production cost. The two hand-held portions 254 can be arranged oppositely or integrally.

[0047] In addition, the adapter can have a positioning portion 255 arranged on the side wall and protruding outward. Correspondingly, the accommodation groove can be provided with a positioning groove. When the adapter is arranged in the accommodation groove, the positioning portion 255 of the adapter can be placed in the positioning groove to limit the rotation of the adapter in the accommodation groove.

[0048] Finally, it should be noted that: the above embodiments are mainly used to illustrate the technical solutions of the present application, and should not be understood as a limitation on the present application; the foregoing embodiments have been described in detail and specifically, and a person of ordinary skill in the art can modify the technical solutions recorded in the foregoing embodiments, or replace part or all of the technical features; and these modifications or replacements cannot make the corresponding technical solutions and the technical solutions of the present application constitute different inventions, and thus should be covered in the scope of the claims and the specification of the present application. Especially, in the absence of structural conflicts or combination barriers, the technical features mentioned in each embodiment can be combined in any way, and these combinations still should not be considered as deviating from the scope of the technical solutions of the present application.

Claims

1. An adapter, characterized in that, The adapter comprises a plurality of assembly holes for assembling centrifuge tubes, wherein the inner surface of at least one of the assembly holes is connected to the outer surface of the sidewall of the adapter, so that when a centrifuge tube is assembled with the assembly hole, part of the sidewall of the centrifuge tube is exposed outside the sidewall of the adapter.

2. The adapter of claim 1, wherein the area where the inner surface of the assembly hole is connected to the outer surface of the sidewall of the adapter forms a gap, and the average width of the gap is less than the average value of the inner diameter of the assembly hole.

3. The adapter of claim 1, wherein the outer diameter of the adapter is 80 mm.

4. The adapter of claim 1, wherein at least two of the plurality of assembly holes are arranged in parallel.

5. The adapter of claim 1, wherein the axial direction of the plurality of assembly holes is parallel to the axial direction of the adapter.

6. The adapter of claim 1, wherein the adapter has a hand-holding portion arranged on the end surface thereof, and the hand-holding portion is arranged offset from the assembly holes.

7. The adapter of claim 1, wherein the adapter has a positioning portion arranged on the sidewall thereof and protruding outward.

8. The adapter of claim 1, wherein the distance between the centers of at least two assembly holes is between 22.3 mm and 35 mm. The centrifuge comprises a housing and the rotor assembly of claim 9, and the housing is used to control the rotation of the rotor assembly.

9. A rotor assembly characterized by, The centrifuge comprises a housing and the rotor assembly of claim 9, and the housing is used to control the rotation of the rotor assembly.

10. A centrifuge characterized by, ​

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